Smad7 and Smad6 bind to discrete regions of Pellino-1 via their MH2 domains to mediate TGF-β1-induced negative regulation of IL-1R/TLR signaling

Biochemical and Biophysical Research Communications

Volumn 393, Issue 4, 2010, Pages 836-843

  Lee, Youn Sook ^a   Kim, Jun Hwan ^a   Kim, Shin Tae ^b   Kwon, Jae Young ^a   Hong, Suntaek ^b   Kim, Seong Jin ^b   Park, Seok Hee ^a  

^a Sungkyunkwan University   (South Korea)

^b Gachon University   (South Korea)

Author keywords

Anti inflammation; IL 1R TLR; Inhibitory Smads; Pellino 1; TGF

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; PELLINO 1; SCAFFOLD PROTEIN; SMAD6 PROTEIN; SMAD7 PROTEIN; TOLL LIKE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ARTICLE; BRAIN REGION; CONTROLLED STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

ANIMALS; CELL LINE; FEMALE; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICE; MICE, INBRED C57BL; NUCLEAR PROTEINS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, INTERLEUKIN-1; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD6 PROTEIN; TOLL-LIKE RECEPTORS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 77949489953     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.02.094     Document Type: Article

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