MAPK signaling downstream to TLR4 contributes to paclitaxel-induced peripheral neuropathy

Brain, Behavior, and Immunity

Volumn 49, Issue , 2015, Pages 255-266

  Li, Yan ^a   Zhang, Hongmei ^a   Kosturakis, Alyssa K ^a,e   Cassidy, Ryan M ^b   Zhang, Haijun ^a,f   Kennamer Chapman, Ross M ^b   Jawad, Abdul Basit ^b   Colomand, Cecilia M ^c   Harrison, Daniel S ^d   Dougherty, Patrick M ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF TEXAS AT BROWNSVILLE   (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^f UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Chemotherapy; Dorsal root ganglion; ERK1 2; NF B; P38; Spinal dorsal horn

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PACLITAXEL; TOLL LIKE RECEPTOR 4; ANTINEOPLASTIC AGENT; TLR4 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DORSAL ROOT; DOSE TIME EFFECT RELATION; DRUG EFFICACY; DRUG RESPONSE; GLIA CELL; HYPERSENSITIVITY; MALE; MOUSE; NERVE CELL; NONHUMAN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SPINAL CORD NERVE CELL; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; RAT; SIGNAL TRANSDUCTION; SPINAL GANGLION; SPRAGUE DAWLEY RAT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; GANGLIA, SPINAL; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; NF-KAPPA B; PACLITAXEL; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; RATS, SPRAGUE-DAWLEY; TOLL-LIKE RECEPTOR 4;

EID: 84940611752     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2015.06.003     Document Type: Article

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