Autophagy inhibition enhances isorhamnetin.induced mitochondria.dependent apoptosis in non-small cell lung cancer cells

Molecular Medicine Reports

Volumn 12, Issue 4, 2015, Pages 5796-5806

  Ruan, Yushu ^a   Hu, Ke ^a   Chen, Hongbo ^b  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b TSINGHUA UNIVERSITY   (China)

Author keywords

3 methyladenine; Apoptosis; Autophagy; Caspase; Isorhamnetin; Lung cancer

Indexed keywords

3 METHYLADENINE; CASPASE 3; CASPASE 9; CHLOROQUINE; CYTOCHROME C; ISORHAMNETIN; MICROTUBULE ASSOCIATED PROTEIN 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; 3-METHYLADENINE; 3-METHYLQUERCETIN; ADENINE; ANTINEOPLASTIC AGENT; CASPASE; HYDROXYCHLOROQUINE; MAP1LC3A PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; QUERCETIN;

A549 CELL LINE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CANCER INHIBITION; CELL PROLIFERATION; CELL VACUOLE; COLONY FORMATION; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; MOUSE; NON SMALL CELL LUNG CANCER; NONHUMAN; PROTEIN EXPRESSION; TUMOR VOLUME; TUMOR XENOGRAFT; ANALOGS AND DERIVATIVES; ANIMAL; CARCINOMA, NON-SMALL-CELL LUNG; DOSE RESPONSE; DRUG EFFECTS; DRUG POTENTIATION; DRUG SCREENING; EPITHELIUM CELL; GENE EXPRESSION; GENETICS; LUNG NEOPLASMS; METABOLISM; NUDE MOUSE; PATHOLOGY; SECRETION (PROCESS); TUMOR CELL LINE;

ADENINE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; AUTOPHAGY; CARCINOMA, NON-SMALL-CELL LUNG; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; EPITHELIAL CELLS; GENE EXPRESSION; HUMANS; HYDROXYCHLOROQUINE; LUNG NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, NUDE; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; QUERCETIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84940549928     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4148     Document Type: Article

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