Hyperinsulinemia enhances hepatic expression of the fatty acid transporter Cd36 and provokes hepatosteatosis and hepatic insulin resistance

Journal of Biological Chemistry

Volumn 290, Issue 31, 2015, Pages 19034-19043

  Steneberg, Pär ^a   Sykaras, Alexandros G ^a   Backlund, Fredrik ^a   Straseviciene, Jurate ^a   Söderström, Ingegerd ^b   Edlund, Helena ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN;

FAT ACCUMULATION; HEPATIC EXPRESSION; HEPATIC INSULIN RESISTANCE; HYPERINSULINEMIA; INSULIN RESISTANCE;

FATTY ACIDS;

CD36 ANTIGEN; FATTY ACID TRANSPORTER; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; C57BL 6 MOUSE; CD36 GENE; CONTROLLED STUDY; DISEASE COURSE; DYSGLYCEMIA; FATTY ACID OXIDATION; FATTY LIVER; GENE TARGETING; HUMAN; HUMAN CELL; HYPERINSULINEMIA; INSULIN RESISTANCE; LIPOGENESIS; LIPOPROTEIN SECRETION; LIVER CELL; LIVER PERFUSION; MALE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PPAR GAMMA GENE; PRIORITY JOURNAL; SUGAR INTAKE; ANIMAL; C3H MOUSE; C57BL MOUSE; CBA MOUSE; GENETICS; HEPG2 CELL LINE; LIVER; METABOLISM; PHYSIOLOGY;

ANIMALS; ANTIGENS, CD36; FATTY LIVER; HEP G2 CELLS; HUMANS; INSULIN; INSULIN RESISTANCE; LIVER; MALE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED CBA; PPAR GAMMA;

EID: 84940532511     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.640292     Document Type: Article

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