Regulation of putative fatty acid transporters and acyl-CoA synthetase in liver and adipose tissue in ob/ob mice

Diabetes

Volumn 48, Issue 1, 1999, Pages 121-127

  Memon, Riaz A ^a,b   Fuller, John ^a,b   Moser, Arthur H ^a,b   Smith, Pamela J ^c   Grunfeld, Carl ^a,b   Feingold, Kenneth R ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; FATTY ACID BINDING PROTEIN; LONG CHAIN FATTY ACID COENZYME A LIGASE;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ESTERIFICATION; FATTY ACID OXIDATION; FATTY ACID TRANSPORT; HYPERLIPIDEMIA; LIPID METABOLISM; LIVER MICROSOME; LIVER MITOCHONDRION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL;

ADIPOSE TISSUE; ANIMALS; ANTIGENS, CD36; CARRIER PROTEINS; COENZYME A LIGASES; FATTY ACID TRANSPORT PROTEINS; FATTY ACID-BINDING PROTEINS; FATTY ACIDS; LIVER; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED C57BL; MYELIN P2 PROTEIN; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; OBESITY; ORGANIC ANION TRANSPORTERS; REPRESSOR PROTEINS; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 0032933114     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.48.1.121     Document Type: Article

References (51)

1. Nestel P, Goldrick B: Obesity: changes in lipid metabolism and the role of insulin. Clin Endocrinol Metab 5:313-335, 1976
2. Schonfeld G, Kelski C, Howald MA: Characterization of the plasma lipoproteins of the genetically obese hyperlipoproteinemic Zucker fatty rat. J Lipid Res 15:457-164, 1974
3. Nishina PM, Lowe S, Wang J, Piagen B: Characterization of plasma lipids in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow. Metabolism 43:549-553, 1994
4. Zucker LM: Fat mobilization in vitro and in vivo in the genetically obese Zucker rat "fatty." J Lipid Res 13:234-243, 1972
5. Martin RJ: In vivo lipogenesis, and enzyme levels in adipose and liver tissues from pair-fed genetically obese and lean rats. Life Sci 14:1447-1453, 1974
6. Memon RA, Grunfeld C, Moser AH, Feingold KR: Fatty acid synthesis in obese insulin resistant diabetic mice. Horm Metab Res 26:85-87, 1994
7. Schonfeld G, Pfleger B: Overproduction of very low density lipoproteins by livers of genetically obese rats. Am J Physiol 220:1178-1181, 1971
8. Wang CS, Fukuda N, Ontko JA: Studies on the mechanism of hypertriglyceridemia in the genetically obese Zucker rat. J Lipid Res 25:571-579, 1984
9. Hartman AD: Lipoprotein lipase activities in adipose tissues and muscle in the Obese Zucker rat. Am J Physiol 241:E108-E115, 1981
10. Rath EA, Hems DA, Beloff-Chain A: lipoprotein lipase activities in tissues of normal and genetically obese (ob/ob) mice. Diabetologia 10:261-260, 1974
11. Fukuda N, Azain MJ, Ontko JA: Altered hepatic metabolism of free fatty acids underlying hypersecretion of very low density lipoproteins in the genetically obese Zucker rats. J Biol Chem 257:14066-14072, 1982
12. Azain MJ, Fukuda N, Chao F, Yamamoto M, Ontko JA: Contribution of fatty acid and sterol synthesis to triglyceride and cholesterol secretion by the perfused rat liver in genetic hyperlipidemia and obesity. J Biol Chem 260:174-181, 1985
13. Faergeman NM, Knudsen J: Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling. Biol J 323:1-12, 1997
14. Berk PD: How do long chain free fatty acids cross cell membranes? Proc Soc Expl Biol Med 212:1-4, 1996
15. Hamilton JA: Fatty acid transport: difficult or easy? J Lipid Res 39:467-481, 1998
16. Zakim D: Fatty acids enter cells by simple diffusion. Proc Soc Expl Biol Med 212:5-14, 1996
17. Kamp K, Zakim D, Zhang F, Noy N, Hamilton JA: Fatty acid flip-flop in phospholipid bilayers is extremely fast. Biochemistry 34:11928-11937, 1995
18. Trigatti B, Gerber GE: The effect of intracellular pH on long-chain fatty acid uptake in 3T3-L1 adipocytes: evidence that uptake involves the passive diffusion of protonated long-chain fatty acids across the plasma membrane. Biochem J 313:487-494, 1996
19. Civelek VN, Hamilton JA, Tornheim K, Kelly KL, Corkey BE: Intrazellular pH in adipocytes: effects of free fatty acid diffusion across the plasma membrane, lipolytic agonists and insulin. Proc Natl Acad Sci U S A 93:10139-10144, 1990
20. Schaffer JE, Lodish HF: Molecular mechanisms of long chain fatty acid uptake. Trends Cardiovasc Med 5:218-224, 1995
21. Abumrad NA, Park PR, Park CR: Permeation of long chain fatty acids into adipocytes: kinetics, specificity, and evidence for involvement of a membrane protein. J Biol Chem 259:8946-8953, 1984
22. Stremmel W, Strohmeyer G, Berk PD: Hepatocellular uptake of oleate is energy dependent, sodium linked and inhibited by an antibody to a plasma membrane fatty acid binding protein. Proc Natl Acad Sci U S A 83:3584-3588, 1986
23. Stremmel W: Fatty acid uptake by isolated rat heart myocytes represents a carrier mediated transport process. J Clin Invest 81:844-852, 1988
24. Turcotte LP, Kiens B, Richter EA: Saturation kinetics of palmitate uptake in perfused skeletal muscle. FEBS Lett 279:327-329, 1991
25. Stremmel W, Strohmeyer G, Borchard Y, Kochwa S, Berk PD: Isolation and partial characterization of a fatty acid binding protein in rat liver plasma membranes. Proc Natl Acad Sci U S A 82:4-8, 1985
26. Abumrad NA, El-Maghrabi MR, Amri EZ, Lopez E, Grimaldi PA: Cloning of a rat adipocyte membrane protein implicated in binding or transport of long chain fatty acids that is induced during preadipocyte differetiation: homology with human CD36. J Biol Chem 268:17665-17668, 1993
27. Schaffer JE, Lodish HF: Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. Cell 79:427-436, 1994
28. Isola LM, Zhou SL, Kiang CL, Stump DD, Bradbury MW, Berk PD: 3T3 fibroblasts transfected with a cDNA for mitochondria asparatate aminotransferase express plasma membrane fatty acid-binding protein and saturable fatty acid uptake. Proc natl Acad Sci U S A 92:9806-9870, 1995
29. Ibrahimi A, Sfeir Z, Magharaie H, Amri EZ, Grimaldi P, Abumrad NA: Expression of the CD36 homolog (FAT) in fibroblast cells: effects on fatty acid transport. Proc Natl Acad Sci U S A 93:2046-2651, 1996
30. Veerkamp JH: Fatty acid transport and fatty acid binding proteins. Proc Nutr Soc 54:23-37, 1995
31. Glatz JFC, van der Vusse GC: Cellular fatty acid binding proteins: their functions and physiological significance. Prog Lipid Res 35:243-282, 1996
32. Suzuki H, Kawarabayasi Y, Kondo J, Abe T, Nishikawa K, Kimura S, Hashimoto T, Yamamoto T: Structure and regulation of rat long-chain acyl-CoA synthetase. J Biol Chem 265:8681-8685, 1990
33. Miyazawa S, Hashimoto T, Yokota S: Identity of long-chain acyl-CoA synthetase of microsomes, mitochondria and peroxisomes in rat liver. J Biochem 98:723-733, 1985
34. Berk PD, Zhou SL, Kiang CL, Stump D, Bradbury M, Isola LM: Uptake of long chain free fatty acids is selectively up-regulated in adipocytes of Zucker rats with genetic obesity and non-insulin-dependent diabetes mellitus. J Biol Chem 272:8830-8835, 1997
35. Misra A, Grag A: Leptin, its receptor and obesity. J Invest Med 44:540-548, 1996
36. Mattingly JR, Rodriguez FJ, Gordon J, Iriatre A, Martinez-Carrion M: Molecular cloning and in vivo expression of a precursor to rat liver mitochondrial aspartate aminotransferase. Biochem Biophys Res Commun 149:859-865, 1987
37. Weiner F, Smith PJ, Wertheimer S, Rubin CS: Regulation of gene expression by insulin and tumor necrosis factor in 3T3-L1 cells: modulation of the transcription of genes encoding acyl-CoA synthatase and stearoyl-CoA desaturase-1. J Biol Chem 200:23525-23528, 1991
38. Chomezynski P, Sacchi N: Single step method of RNA Isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159, 1987
39. Feingold KR, Hardardottir I, Memon RA, Krul EJT, Moser AH, Taylor JM, Grunfeld C: Effect of endotoxin on cholesterol biosynthesis and distribution in serum lipoproteins in Syrian hamsters. J Lipid Res 34:2147-2158, 1993
40. Tanaka T, Hosaka K, Hoshimaru M, Numa S: Purification and properties of longchain acyl-CoA synthetase from rat liver. Eur J Biochem 98:165-172, 1979
41. Memon RA, Fuller J, Smith PJ, Moser AH, Feingold KR, Grunfeld C: In vivo regulation of acyl-CoA synthetase mRNA and activity by endotoxin and cytokines. Am J Physiol 275:E64-E72, 1998
42. Fleischer S, Kervina M: Subcellular fractionation of rat liver. Method Enzymol 31:6-41, 1974
43. Flier JS, Cook KS, Usher P, Spiegelman BM: Severely impaired adipsin expression in genetic and acquired obesity. Science 237:405-408, 1987
44. Memon RA, Feingold KR, Moser AH, Fuller J, Grunfeld C: Regulation of fatty acid transport protein and fatty acid translocase mRNA levels by endotoxin and cytokines. Am J Physiol 274:E210-E217, 1998
45. Memon RA, Feingold KR, Grunfeld C: The effects of cytokines on intermediary metabolism. Endocrinologist 4:56-63, 1994
46. Martin G, Schoonjans K, Lefebvre AM, Staels B, Auwerx J: Coordinate regulation of the expression of the fatty acid transport protein and the acyl-CoA synthetase genes by PPARα and PPARγ activators. J Biol Chem 272:28210-28217, 1997
47. Shimomura I, Tokunaga K, Jiao S, Funahashi T, Keno Y, Kobatake T, Kotani K, Suzuki H, Yamamoto T, Tarui S, Matsuzawa Y: Marked enhancement of acyl-CoA synthetase activity and mRNA, paralleled to lipoprotein lipase mRNA, in adipose tissue of Zucker obese rats. Biochim Biophys Acta 1124:112-118, 1992
48. Chua SC Jr, Chung WK, Wu-Peng XS, Zhang Y, Liu SM, Tartaglia L, Leibel RL: Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor. Science 271:994-996, 1996
49. Zhang Y, Proneca R, Maffei M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432, 1994
50. Tartaglia LA: The leptin receptor. J Biol Chem 272:6093-6096, 1997
51. Fei H, Okano HJ, Li C, Lee GH, Zhao C, Darnell R, Friedman JM: Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proc Natl Acad Sci U S A 94:7001-7005, 1997