Insulin resistance prevents AMPK-induced tau dephosphorylation through akt-mediated increase in AMPKSer-485 phosphorylation

Journal of Biological Chemistry

Volumn 290, Issue 31, 2015, Pages 19146-119157

  Kim, Bhumsoo ^a   Figueroa Romero, Claudia ^a   Pacut, Crystal ^a   Backus, Carey ^a   Feldman, Eva L ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; METABOLISM; NEURODEGENERATIVE DISEASES;

ALZHEIMER DISEASE; DEPHOSPHORYLATIONS; INSULIN RESISTANCE; METABOLIC SYNDROMES; RISK FACTORS;

PHOSPHORYLATION;

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; SERINE; TAU PROTEIN; THREONINE; ADENYLATE KINASE; PHOSPHOSERINE; PROTEIN KINASE B;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INSULIN RESISTANCE; MOUSE; NONHUMAN; OBESITY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; RAT; RISK FACTOR; UPREGULATION; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; CELL LINE; COMPLICATION; DIABETES COMPLICATIONS; LIPID DIET; METABOLISM; MOUSE MUTANT; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING;

ADENYLATE KINASE; ALZHEIMER DISEASE; ANIMALS; CELL LINE; DIABETES COMPLICATIONS; DIET, HIGH-FAT; HUMANS; INSULIN RESISTANCE; MICE, INBRED C57BL; MICE, OBESE; OBESITY; PHOSPHORYLATION; PHOSPHOSERINE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; RISK FACTORS; TAU PROTEINS;

EID: 84940497802     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.636852     Document Type: Article

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