-
1
-
-
0037283601
-
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes
-
Kahn SE. The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes. Diabetologia 2003; 46:3-19. (Pubitemid 36237741)
-
(2003)
Diabetologia
, vol.46
, Issue.1
, pp. 3-19
-
-
Kahn, S.E.1
-
2
-
-
12744263199
-
Islet adaptation to insulin resistance: Mechanisms and implications for interventions
-
Ahrén B, Pacini G. Islet adaptation to insulin resistance: Mechanisms and implications for interventions. Diabetes Obes Metab 2005; 7:2-8.
-
(2005)
Diabetes Obes Metab
, vol.7
, pp. 2-8
-
-
Ahrén, B.1
Pacini, G.2
-
3
-
-
0024834748
-
Toward physiological understanding of glucose tolerance. Minimal-model approach
-
Bergman RN. Toward physiological understanding of glucose tolerance. Minimal-model approach. Diabetes 1989; 38:1512-27.
-
(1989)
Diabetes
, vol.38
, pp. 1512-1527
-
-
Bergman, R.N.1
-
4
-
-
0029816099
-
Failure to adequately adapt reduced insulin sensitivity with increased insulin secretion in women with impaired gluose tolerance
-
DOI 10.1007/s001250050559
-
Larsson H, Ahrén B. Failure to adequately adapt reduced insulin sensitivity with increased insulin secretion in women with impaired glucose tolerance. Diabetologia 1996; 39:1099-107. (Pubitemid 26275941)
-
(1996)
Diabetologia
, vol.39
, Issue.9
, pp. 1099-1107
-
-
Larsson, H.1
Ahren, B.2
-
5
-
-
18644376240
-
Type 2 diabetes, insulin secretion and β-cell mass
-
Ahrén B. Type 2 diabetes, insulin secretion and β-cell mass. Curr Mol Med 2005; 5:275-86.
-
(2005)
Curr Mol Med
, vol.5
, pp. 275-286
-
-
Ahrén, B.1
-
6
-
-
0042822112
-
Increased beta-cell apoptosis prevents adaptive increase in betacell mass in mouse model of type 2 diabetes: Evidence for role of islet amyloid formation rather than direct action of amyloid
-
Butler AE, Janson J, Soeller WC, Butler PC. Increased beta-cell apoptosis prevents adaptive increase in betacell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid. Diabetes 2003; 52:2304-14.
-
(2003)
Diabetes
, vol.52
, pp. 2304-2314
-
-
Butler, A.E.1
Janson, J.2
Soeller, W.C.3
Butler, P.C.4
-
7
-
-
0037677695
-
Increased islet volume but unchanged islet number in ob/ob mice
-
Bock T, Pakkenberg B, Bushcard K. Increased islet volume but unchanged islet number in ob/ob mice. Diabetes 2003; 52:1716-22. (Pubitemid 36792462)
-
(2003)
Diabetes
, vol.52
, Issue.7
, pp. 1716-1722
-
-
Bock, T.1
Pakkenberg, B.2
Buschard, K.3
-
8
-
-
0037219411
-
β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes
-
Butler A, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes. Diabetes 2003; 52:102-10.
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
9
-
-
0021777067
-
Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited
-
Klöppel G, Löhr M, Habich K, Oberholzer M, Heitz PU. Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited. Surv Synth Pathol 1985; 4:110-25.
-
(1985)
Surv Synth Pathol
, vol.4
, pp. 110-125
-
-
Klöppel, G.1
Löhr, M.2
Habich, K.3
Oberholzer, M.4
Heitz, P.U.5
-
10
-
-
25444455671
-
Regulation of pancreatic betacell mass
-
Bouwens L, Rooman I. Regulation of pancreatic betacell mass. Physiol Rev 2005; 85:1255-70.
-
(2005)
Physiol Rev
, vol.85
, pp. 1255-1270
-
-
Bouwens, L.1
Rooman, I.2
-
11
-
-
35448986170
-
The replication of β-cells in normal physiology, in disease and for therapy
-
Butler PC, Meier JJ, Butler AE, Bhushan A. The replication of β-cells in normal physiology, in disease and for therapy. Nat Clin Pract Endocrinol Metab 2007; 3:758-68.
-
(2007)
Nat Clin Pract Endocrinol Metab
, vol.3
, pp. 758-768
-
-
Butler, P.C.1
Meier, J.J.2
Butler, A.E.3
Bhushan, A.4
-
12
-
-
66449093171
-
Meeting the demand for insulin: Molecular mechanisms of adaptive postnatal β-cell mass expansion
-
Sachdeva MM, Stoffers DA. Meeting the demand for insulin: molecular mechanisms of adaptive postnatal β-cell mass expansion. Mol Endocrinol 2009; 23:747-58.
-
(2009)
Mol Endocrinol
, vol.23
, pp. 747-758
-
-
Sachdeva, M.M.1
Stoffers, D.A.2
-
13
-
-
38749108893
-
B cells can be generated from endogenous progenitors in injured adult mouse pancreas
-
Xu X, D'Hoker J, Stangé G, Bonné S, De Leu N, Xiao X, et al. B cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell 2008; 132:197-207.
-
(2008)
Cell
, vol.132
, pp. 197-207
-
-
Xu, X.1
D'Hoker, J.2
Stangé, G.3
Bonné, S.4
De Leu, N.5
Xiao, X.6
-
14
-
-
0031016595
-
Dissociated insulinotropic sensitivity to glucose and carbachol in high-fat diuet-induced insulin resistance in C57BL/6J mice
-
Ahrén B, Simonsson E, Scheurink AJ, Mulder H, Myrsén U, Sundler F. Dissociated insulinotropic sensitivity to glucose and carbachol in high-fat diuet-induced insulin resistance in C57BL/6J mice. Metabolism 1997; 46:97-106.
-
(1997)
Metabolism
, vol.46
, pp. 97-106
-
-
Ahrén, B.1
Simonsson, E.2
Scheurink, A.J.3
Mulder, H.4
Myrsén, U.5
Sundler, F.6
-
15
-
-
3543009434
-
The high-fat diet-fed mouse: A model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes
-
Winzell MS, Ahrén B. The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes. Diabetes 2004; 53:215-9.
-
(2004)
Diabetes
, vol.53
, pp. 215-219
-
-
Winzell, M.S.1
Ahrén, B.2
-
16
-
-
33845189881
-
Temporal and dietary fat content-dependent islet adaptation to high-fat feeding-induced glucose intolerance in mice
-
DOI 10.1016/j.metabol.2006.09.008, PII S0026049506003398
-
Winzell MS, Magnusson C, Ahrén B. Temporal and dietary fat content-dependent islet adaptation to high-fat feeding-induced glucose intolerance in mice. Metabolism 2007; 56:122-8. (Pubitemid 44855020)
-
(2007)
Metabolism: Clinical and Experimental
, vol.56
, Issue.1
, pp. 122-128
-
-
Winzell, M.S.1
Magnusson, C.2
Ahren, B.3
-
17
-
-
0036785664
-
Insufficient islet compensation to insulin resistance vs reduced glucose effectiveness in glucose-intolerant mice
-
Ahrén B, Pacini G. Insufficient islet compensation to insulin resistance vs reduced glucose effectiveness in glucose-intolerant mice. Am J Physiol 2002; 283:738-44.
-
(2002)
Am J Physiol
, vol.283
, pp. 738-744
-
-
Ahrén, B.1
Pacini, G.2
-
18
-
-
0032486135
-
Potentiated beta-cell response to non-glucose stimuli in insulin-resistant CX57BL/6J mice
-
Simonsson E, Ahrén B. Potentiated beta-cell response to non-glucose stimuli in insulin-resistant CX57BL/6J mice. Eur J Pharmacol 1998; 350:243-50.
-
(1998)
Eur J Pharmacol
, vol.350
, pp. 243-250
-
-
Simonsson, E.1
Ahrén, B.2
-
19
-
-
23944525524
-
Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release: Evidence for specificity of impaired beta cell adaptation
-
Hull RL, Kodama K, Utzschneider KM, Carr DB, Prigeon RL, Kahn SE. Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release: evidence for specificity of impaired beta cell adaptation. Diabetologia 2005; 48:1350-8.
-
(2005)
Diabetologia
, vol.48
, pp. 1350-1358
-
-
Hull, R.L.1
Kodama, K.2
Utzschneider, K.M.3
Carr, D.B.4
Prigeon, R.L.5
Kahn, S.E.6
-
20
-
-
52749093177
-
Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet
-
Ebato C, Uchida T, Arakawa M, Komatsu M, Ueno T, Komiya K, et al. Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet. Cell Metab 2008; 8:325-32.
-
(2008)
Cell Metab
, vol.8
, pp. 325-332
-
-
Ebato, C.1
Uchida, T.2
Arakawa, M.3
Komatsu, M.4
Ueno, T.5
Komiya, K.6
-
21
-
-
67349201387
-
Normal islet vascularization is dispensable for expansion of beta-cell mass in response to high-fat diet induced insulin resistance
-
Toyofuku Y, Uchida T, Nakayama S, Hirose T, Kawamori R, Fujitani Y, et al. Normal islet vascularization is dispensable for expansion of beta-cell mass in response to high-fat diet induced insulin resistance. Biochem Biophys Res Commun 2009; 383:303-7.
-
(2009)
Biochem Biophys Res Commun
, vol.383
, pp. 303-307
-
-
Toyofuku, Y.1
Uchida, T.2
Nakayama, S.3
Hirose, T.4
Kawamori, R.5
Fujitani, Y.6
-
22
-
-
77956373690
-
β-Cell failure in diet-induced obese mice stratified according to body weight gain: Secretory dysfunction and altered islet lipid metabolism without steatosis or reduced β-cell mass
-
Peyot ML, Pepin E, Lamontagne J, Lantour MG, Zarrouki B, Lussier R, et al. β-Cell failure in diet-induced obese mice stratified according to body weight gain: Secretory dysfunction and altered islet lipid metabolism without steatosis or reduced β-cell mass. Diabetes 2010;59:2178-87.
-
(2010)
Diabetes
, vol.59
, pp. 2178-2187
-
-
Peyot, M.L.1
Pepin, E.2
Lamontagne, J.3
Lantour, M.G.4
Zarrouki, B.5
Lussier, R.6
-
23
-
-
0032997068
-
Plasma leptin and insulin in C57BL/6J mice on a high-fat diet: Relation to subsequent changes in body weight
-
Ahrén B. Plasma leptin and insulin in C57BL/6J mice on a high-fat diet: relation to subsequent changes in body weight. Acta Physiol Scand 1999; 165:233-40.
-
(1999)
Acta Physiol Scand
, vol.165
, pp. 233-240
-
-
Ahrén, B.1
-
24
-
-
32544435755
-
Insights into fatty acid modulation of panceatic beta-cell function
-
Haber EP, Procopio J, Carvalho CR, Carpinelli AR, Newsholme P, Curi R. Insights into fatty acid modulation of panceatic beta-cell function. Int Rev Cytol 2006; 248:1-41.
-
(2006)
Int Rev Cytol
, vol.248
, pp. 1-41
-
-
Haber, E.P.1
Procopio, J.2
Carvalho, C.R.3
Carpinelli, A.R.4
Newsholme, P.5
Curi, R.6
-
25
-
-
44949143027
-
Glucose and leptin induce apoptosis in human β-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases
-
Maedler K, Schulthess FT, Bielman C, Berney T, Bonny C, Prentki M, et al. Glucose and leptin induce apoptosis in human β-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases. FASEB J 2008; 22:1905-13.
-
(2008)
FASEB J
, vol.22
, pp. 1905-1913
-
-
Maedler, K.1
Schulthess, F.T.2
Bielman, C.3
Berney, T.4
Bonny, C.5
Prentki, M.6
-
26
-
-
0742287922
-
Cocaine- And Amphetamine-regulated Transcript (CART) Is Expressed in Several Islet Cell Types during Rat Development
-
Wierup N, Kuhar M, Nilsson BO, Mulder H, Ekblad E, Sundler F. Cocaine- and amphetamine-regulated transcript (CART) is expressed in several islet cell types during rat development. J Histochem Cytochem 2004; 52:169-77. (Pubitemid 38146575)
-
(2004)
Journal of Histochemistry and Cytochemistry
, vol.52
, Issue.2
, pp. 169-177
-
-
Wierup, N.1
Kuhar, M.2
Nilsson, B.O.3
Mulder, H.4
Ekblad, E.5
Sundler, F.6
-
27
-
-
2442423329
-
Beta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance and deranged islet morphology
-
Härndahl L, Wierup N, Enerbäck S, Mulder H, Manganiello VC, Sundler F, et al. Beta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance and deranged islet morphology. J Biol Chem 2004; 279:15214-22.
-
(2004)
J Biol Chem
, vol.279
, pp. 15214-15222
-
-
Härndahl, L.1
Wierup, N.2
Enerbäck, S.3
Mulder, H.4
Manganiello, V.C.5
Sundler, F.6
|