메뉴 건너뛰기




Volumn 152, Issue 8, 2011, Pages 3143-3154

Suppression of AMPK activation via S485 phosphorylation by IGF-I during hyperglycemia is mediated by AKT activation in vascular smooth muscle cells

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; SHORT HAIRPIN RNA; SOMATOMEDIN C;

EID: 79960746886     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-0155     Document Type: Article
Times cited : (95)

References (45)
  • 1
    • 34249794018 scopus 로고    scopus 로고
    • Hyperglycemia alters the responsiveness of smooth muscle cells to insulin-like growth factor-I
    • DOI 10.1210/en.2006-1440
    • Maile LA, Capps BE, Ling Y, Xi G, Clemmons DR 2007 Hyperglycemia alters the responsiveness of smooth muscle cells to insulin-like growth factor-I. Endocrinology 148:2435-2443 (Pubitemid 46997046)
    • (2007) Endocrinology , vol.148 , Issue.5 , pp. 2435-2443
    • Maile, L.A.1    Capps, B.E.2    Ling, Y.3    Xi, G.4    Clemmons, D.R.5
  • 2
    • 47749131217 scopus 로고    scopus 로고
    • Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells
    • Radhakrishnan Y, Maile LA, Ling Y, Graves LM, Clemmons DR 2008 Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells. J Biol Chem 283:16320-16331
    • (2008) J Biol Chem , vol.283 , pp. 16320-16331
    • Radhakrishnan, Y.1    Maile, L.A.2    Ling, Y.3    Graves, L.M.4    Clemmons, D.R.5
  • 3
    • 0031717105 scopus 로고    scopus 로고
    • The AMP-activated/SNF1 protein kinase subfamily:metabolic sensors of the eukaryotic cell?
    • Hardie DG, Carling D, Carslon M 1998 The AMP-activated/SNF1 protein kinase subfamily:metabolic sensors of the eukaryotic cell? Annu Rev Biochem 67:821-855
    • (1998) Annu Rev Biochem , vol.67 , pp. 821-855
    • Hardie, D.G.1    Carling, D.2    Carslon, M.3
  • 4
    • 0347318052 scopus 로고    scopus 로고
    • The AMP-activated protein kinase cascade - A unifying system for energy control
    • DOI 10.1016/j.tibs.2003.11.005
    • Carling D 2004 The AMP-activated protein kinase cascade: a unifying system for energy control. Trends Biochem Sci 29:18-24 (Pubitemid 38068476)
    • (2004) Trends in Biochemical Sciences , vol.29 , Issue.1 , pp. 18-24
    • Carling, D.1
  • 5
    • 0345167800 scopus 로고    scopus 로고
    • TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
    • DOI 10.1016/S0092-8674(03)00929-2
    • Inoki K, Zhu T, Guan KL 2003 TSC2 mediates cellular energy response to control cell growth and survival. Cell 115:577-590 (Pubitemid 37506046)
    • (2003) Cell , vol.115 , Issue.5 , pp. 577-590
    • Inoki, K.1    Zhu, T.2    Guan, K.-L.3
  • 6
    • 34547105803 scopus 로고    scopus 로고
    • Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794
    • DOI 10.1074/jbc.M610101200
    • Tzatsos A, Tsichlis PN 2007 Energy depletion inhibits phosphatdylinositol 3-kinase/AKt signaling and induces apoptosis via AMP activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794. J Biol Chem 282:18069-18082 (Pubitemid 47100251)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.25 , pp. 18069-18082
    • Tzatsos, A.1    Tsichlis, P.N.2
  • 7
    • 77954831536 scopus 로고    scopus 로고
    • AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation
    • Ning J, Clemmons DR 2010 AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation. Mol Endocrinol 24:1218-1229
    • (2010) Mol Endocrinol , vol.24 , pp. 1218-1229
    • Ning, J.1    Clemmons, D.R.2
  • 9
    • 50649099634 scopus 로고    scopus 로고
    • P66shc negatively regulates insulin-like growth factor I signal transduction via inhibition of p52shc binding to Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 leading to impaired growth factor receptor-bound protein-2 membrane recruitment
    • Xi G, Shen X, Clemmons DR 2008 p66shc negatively regulates insulin-like growth factor I signal transduction via inhibition of p52shc binding to Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 leading to impaired growth factor receptor-bound protein-2 membrane recruitment. Mol Endocrinol 22:2162-2175
    • (2008) Mol Endocrinol , vol.22 , pp. 2162-2175
    • Xi, G.1    Shen, X.2    Clemmons, D.R.3
  • 10
    • 0034455127 scopus 로고    scopus 로고
    • Thrombospondin and osteopontin bind to insulin-like growth factor (IGF)-binding protein-5 leading to an alteration in IGF-I-stimulated cell growth
    • DOI 10.1210/en.141.3.1100
    • Nam TJ, Busby Jr WH, Rees C, Clemmons DR 2000 Thrombospondin and osteopontin bind to insulin-like growth factor (IGF)-binding protein-5 leading to an alteration in IGF-I-stimulated cell growth. Endocrinology 141:1100-1106 (Pubitemid 32266071)
    • (2000) Endocrinology , vol.141 , Issue.3 , pp. 1100-1106
    • Nam, T.-J.1    Busby Jr., W.H.2    Rees, C.3    Clemmons, D.R.4
  • 11
    • 58149340146 scopus 로고    scopus 로고
    • Integrin-associated protein association with SRC homology 2 domain containing tyrosine phosphatase substrate 1 regulates IGF-I signaling in vivo
    • Maile LA, Capps BE, Miller EC, Aday AW, Clemmons DR 2008 Integrin-associated protein association with SRC homology 2 domain containing tyrosine phosphatase substrate 1 regulates IGF-I signaling in vivo. Diabetes 57:2637-2643
    • (2008) Diabetes , vol.57 , pp. 2637-2643
    • Maile, L.A.1    Capps, B.E.2    Miller, E.C.3    Aday, A.W.4    Clemmons, D.R.5
  • 13
    • 43049121395 scopus 로고    scopus 로고
    • Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt
    • Fulco M, Cen Y, Zhao P, Hoffman EP, McBurney MW, Sauve AA, Sartorelli V 2008 Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Dev Cell 14:661-673
    • (2008) Dev Cell , vol.14 , pp. 661-673
    • Fulco, M.1    Cen, Y.2    Zhao, P.3    Hoffman, E.P.4    McBurney, M.W.5    Sauve, A.A.6    Sartorelli, V.7
  • 16
    • 43049104174 scopus 로고    scopus 로고
    • Glucose regulation of integrin-associated protein cleavage controls the response of vascular smooth muscle cells to insulin-like growth factor-I
    • DOI 10.1210/me.2007-0552
    • Maile LA, Capps BE, Miller EC, Allen LB, Veluvolu U, Aday AW, Clemmons DR 2008 Glucose regulation of integrin-associated protein cleavage controls the response of vascular smooth muscle cells to insulin-like growth factor-I. Mol Endocrinol 22:1226-1237 (Pubitemid 351629621)
    • (2008) Molecular Endocrinology , vol.22 , Issue.5 , pp. 1226-1237
    • Maile, L.A.1    Capps, B.E.2    Miller, E.C.3    Allen, L.B.4    Veluvolu, U.5    Aday, A.W.6    Clemmons, D.R.7
  • 18
    • 51649125241 scopus 로고    scopus 로고
    • IGFBP-5 regulates muscle cell differentiation by binding to IGF-II and switching on the IGF-II autoregulation loop
    • Ren H, Yin P, Duan C 2008 IGFBP-5 regulates muscle cell differentiation by binding to IGF-II and switching on the IGF-II autoregulation loop. J Cell Biol 182:979-991
    • (2008) J Cell Biol , vol.182 , pp. 979-991
    • Ren, H.1    Yin, P.2    Duan, C.3
  • 19
    • 0033304619 scopus 로고    scopus 로고
    • Roles of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in stimulation of vascular smooth muscle cell migration and deoxyribonucleic acid synthesis by insulin-like growth factor-I
    • Imai Y, Clemmons DR 1999 Roles of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in stimulation of vascular smooth muscle cell migration and deoxyribonucleic acid synthesis by insulin-like growth factor-I. Endocrinology 140:4228-4235 (Pubitemid 30647121)
    • (1999) Endocrinology , vol.140 , Issue.9 , pp. 4228-4235
    • Imai, Y.1    Clemmons, D.R.2
  • 20
    • 32944461233 scopus 로고    scopus 로고
    • Thiazolidinediones inhibit insulin-like growth factor-i-induced activation of p70S6 kinase and suppress insulin-like growth factor-I tumor-promoting activity
    • He G, Sung YM, Digiovanni J, Fischer SM 2006 Thiazolidinediones inhibit insulin-like growth factor-i-induced activation of p70S6 kinase and suppress insulin-like growth factor-I tumor-promoting activity. Cancer Res 66:1873-1878
    • (2006) Cancer Res , vol.66 , pp. 1873-1878
    • He, G.1    Sung, Y.M.2    Digiovanni, J.3    Fischer, S.M.4
  • 21
    • 0035374673 scopus 로고    scopus 로고
    • Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1- And epidermal growth factor-dependent extracellular signal-regulated kinase pathway
    • Kim J, Yoon MY, Choi SL, Kang I, Kim SS, Kim YS, Choi YK, Ha J 2001 Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1- and epidermal growth factor-dependent extracellular signal-regulated kinase pathway. J Biol Chem 276:19102-19110
    • (2001) J Biol Chem , vol.276 , pp. 19102-19110
    • Kim, J.1    Yoon, M.Y.2    Choi, S.L.3    Kang, I.4    Kim, S.S.5    Kim, Y.S.6    Choi, Y.K.7    Ha, J.8
  • 23
    • 78751485448 scopus 로고    scopus 로고
    • Insulin receptor substrates Irs1 and Irs2 coordinate skeletal muscle growth and metabolism via the Akt and AMPK pathways
    • Long YC, Cheng Z, Copps KD, White MF 2011 Insulin receptor substrates Irs1 and Irs2 coordinate skeletal muscle growth and metabolism via the Akt and AMPK pathways. Mol Cell Biol 31:430-441
    • (2011) Mol Cell Biol , vol.31 , pp. 430-441
    • Long, Y.C.1    Cheng, Z.2    Copps, K.D.3    White, M.F.4
  • 24
    • 48049113458 scopus 로고    scopus 로고
    • Berberine inhibits platelet-derived growth factor-induced growth and migration partly through an AMPK-dependent pathway in vascular smooth muscle cells
    • Liang KW, Yin SC, Ting CT, Lin SJ, Hsueh CM, Chen CY, Hsu SL 2008 Berberine inhibits platelet-derived growth factor-induced growth and migration partly through an AMPK-dependent pathway in vascular smooth muscle cells. Eur J Pharmacol 590:343-354
    • (2008) Eur J Pharmacol , vol.590 , pp. 343-354
    • Liang, K.W.1    Yin, S.C.2    Ting, C.T.3    Lin, S.J.4    Hsueh, C.M.5    Chen, C.Y.6    Hsu, S.L.7
  • 25
    • 77956528144 scopus 로고    scopus 로고
    • PDK1 recruitment to the SHPS-1 signaling complex enhances insulin-like growth factor-I-stimulated AKT activation and vascular smooth muscle cell survival
    • Shen X, Xi G, Radhakrishnan Y, Clemmons DR 2010 PDK1 recruitment to the SHPS-1 signaling complex enhances insulin-like growth factor-I-stimulated AKT activation and vascular smooth muscle cell survival. J Biol Chem 285:29416-29424
    • (2010) J Biol Chem , vol.285 , pp. 29416-29424
    • Shen, X.1    Xi, G.2    Radhakrishnan, Y.3    Clemmons, D.R.4
  • 26
    • 33646828975 scopus 로고    scopus 로고
    • Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491
    • Horman S, Vertommen D, Heath R, Neumann D, Mouton V, Woods A, Schlattner U, Wallimann T, Carling D, Hue L, Rider MH 2006 Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491. J Biol Chem 281: 5335-5340
    • (2006) J Biol Chem , vol.281 , pp. 5335-5340
    • Horman, S.1    Vertommen, D.2    Heath, R.3    Neumann, D.4    Mouton, V.5    Woods, A.6    Schlattner, U.7    Wallimann, T.8    Carling, D.9    Hue, L.10    Rider, M.H.11
  • 28
    • 33744937886 scopus 로고    scopus 로고
    • Activation of cardiac AMP-activated protein kinase by LKB1 expression or chemical hypoxia is blunted by increased Akt activity
    • DOI 10.1152/ajpheart.01206.2005
    • Soltys CL, Kovacic S, Dyck JR 2006 Activation of cardiac AMP-activated protein kinase by LKB1 expression or chemical hypoxia is blunted by increased Akt activity. Am J Physiol Heart Circ Physiol 290:H2472-H2479 (Pubitemid 43846078)
    • (2006) American Journal of Physiology - Heart and Circulatory Physiology , vol.290 , Issue.6
    • Soltys, C.-L.M.1    Kovacic, S.2    Dyck, J.R.B.3
  • 30
    • 79551601710 scopus 로고    scopus 로고
    • Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1- independent pathway
    • Kitada M, Kume S, Imaizumi N, Koya D 2011 Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1-independent pathway. Diabetes 60:634-643
    • (2011) Diabetes , vol.60 , pp. 634-643
    • Kitada, M.1    Kume, S.2    Imaizumi, N.3    Koya, D.4
  • 31
    • 78649367703 scopus 로고    scopus 로고
    • Losartan inhibits vascular smooth muscle cell proliferation through activation of AMP-activated protein kinase
    • Kim JE, Choi HC 2010 Losartan inhibits vascular smooth muscle cell proliferation through activation of AMP-activated protein kinase. Korean J Physiol Pharmacol 14:299-304
    • (2010) Korean J Physiol Pharmacol , vol.14 , pp. 299-304
    • Kim, J.E.1    Choi, H.C.2
  • 32
    • 33847690643 scopus 로고    scopus 로고
    • Adiponectin actions in the cardiovascular system
    • DOI 10.1016/j.cardiores.2006.10.009, PII S0008636306004664
    • Hopkins TA, Ouchi N, Shibata R, Walsh K 2007 Adiponectin actions in the cardiovascular system. Cardiovasc Res 74:11-18 (Pubitemid 46366942)
    • (2007) Cardiovascular Research , vol.74 , Issue.1 , pp. 11-18
    • Hopkins, T.A.1    Ouchi, N.2    Shibata, R.3    Walsh, K.4
  • 35
    • 79960048104 scopus 로고    scopus 로고
    • Regulation of G1 cell cycle progression: Distinguishing the restriction point from a nutrient-sensing cell growth checkpoints
    • Foster AD, Yellen P, Xu L, Saqcena M 2011 Regulation of G1 cell cycle progression: Distinguishing the restriction point from a nutrient-sensing cell growth checkpoints. Genes and Cancer 1:1124-1131
    • (2011) Genes and Cancer , vol.1 , pp. 1124-1131
    • Foster, A.D.1    Yellen, P.2    Xu, L.3    Saqcena, M.4
  • 36
    • 33745213627 scopus 로고    scopus 로고
    • AMPK and cell proliferation - AMPK as a therapeutic target for atherosclerosis and cancer
    • DOI 10.1113/jphysiol.2006.108324
    • Motoshima H, Goldstein BJ, Igata M, Araki E 2006 AMPK and cell proliferation: AMPK as a therapeutic target for atherosclerosis and cancer. J Physiol 574:63-71 (Pubitemid 43905797)
    • (2006) Journal of Physiology , vol.574 , Issue.1 , pp. 63-71
    • Motoshima, H.1    Goldstein, B.J.2    Igata, M.3    Araki, E.4
  • 37
    • 20844449238 scopus 로고    scopus 로고
    • AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
    • DOI 10.1016/j.molcel.2005.03.027, PII S1097276505012207
    • Jones RG, Plas DR, Kubek S, Buzzai M, Mu J, Xu Y, Birnbaum MJ, Thompson CB 2005 AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell 18:283-293 (Pubitemid 41350534)
    • (2005) Molecular Cell , vol.18 , Issue.3 , pp. 283-293
    • Jones, R.G.1    Plas, D.R.2    Kubek, S.3    Buzzai, M.4    Mu, J.5    Xu, Y.6    Birnbaum, M.J.7    Thompson, C.B.8
  • 38
    • 77952163120 scopus 로고    scopus 로고
    • p53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment
    • Feng Z 2010 p53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment. Cold Spring Harb Perspect Biol 2:a001057
    • (2010) Cold Spring Harb Perspect Biol , vol.2
    • Feng, Z.1
  • 39
    • 34248194200 scopus 로고    scopus 로고
    • The regulation of AMPK β1, TSC2, and PTEN expression by p53: Stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways
    • DOI 10.1158/0008-5472.CAN-06-4149
    • Feng Z, Hu W, de Stanchina E, Teresky AK, Jin S, Lowe S, Levine AJ 2007 The regulation of AMPK β1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways. Cancer Res 67:3043-3053 (Pubitemid 46724841)
    • (2007) Cancer Research , vol.67 , Issue.7 , pp. 3043-3053
    • Feng, Z.1    Hu, W.2    De Stanchina, E.3    Teresky, A.K.4    Jin, S.5    Lowe, S.6    Levine, A.J.7
  • 40
    • 0034680932 scopus 로고    scopus 로고
    • Insulin-like growth factor-I extends in vitro replicative life span of skeletal muscle satellite cells by enhancing G1/S cell cycle progression via the activation of phosphatidylinositol 3′kinase/Akt signaling pathway
    • Chakravarthy MV, Abraha TW, Schwartz RJ, Fiorotto ML, Booth FW2000 Insulin-like growth factor-I extends in vitro replicative life span of skeletal muscle satellite cells by enhancing G1/S cell cycle progression via the activation of phosphatidylinositol 3′kinase/Akt signaling pathway. J Biol Chem 17:35942-35952
    • (2000) J Biol Chem , vol.17 , pp. 35942-35952
    • Chakravarthy, M.V.1    Abraha, T.W.2    Schwartz, R.J.3    Fiorotto, M.L.4    Booth, F.W.5
  • 41
    • 77953662891 scopus 로고    scopus 로고
    • Diabetes, hyperglycemia and accelerated atherosclerosis: Evidence supporting a role for endoplasmic reticulum (ER) stress signaling
    • McApline CS, Bowes AJ, Werstuck GH 2010 Diabetes, hyperglycemia and accelerated atherosclerosis: evidence supporting a role for endoplasmic reticulum (ER) stress signaling. Cardiovasc Hematol Disord Drug Targets 10:151-157
    • (2010) Cardiovasc Hematol Disord Drug Targets , vol.10 , pp. 151-157
    • McApline, C.S.1    Bowes, A.J.2    Werstuck, G.H.3
  • 42
    • 77949462458 scopus 로고    scopus 로고
    • AMPK as a metabolic tumor suppressor: Control of metabolism and cell growth
    • Luo Z, Zang M, Guo W 2010 AMPK as a metabolic tumor suppressor: control of metabolism and cell growth. Future Oncol 6:457-470
    • (2010) Future Oncol , vol.6 , pp. 457-470
    • Luo, Z.1    Zang, M.2    Guo, W.3
  • 43
    • 67549131188 scopus 로고    scopus 로고
    • Energy homeostasis and cancer prevention: The AMP-activated protein kinase
    • Phila
    • Fay JR, Steele V, Crowell JA 2009 Energy homeostasis and cancer prevention: the AMP-activated protein kinase. Cancer Prev Res (Phila) 2:301-309
    • (2009) Cancer Prev Res , vol.2 , pp. 301-309
    • Fay, J.R.1    Steele, V.2    Crowell, J.A.3
  • 45
    • 78649816080 scopus 로고    scopus 로고
    • Mammalian target of rapamycin inhibition abrogates insulin-mediated mammary tumor progression in type 2 diabetes
    • Fierz Y, Novosyadlyy R, Vijayakumar A, Yakar S, LeRoith D 2010 Mammalian target of rapamycin inhibition abrogates insulin-mediated mammary tumor progression in type 2 diabetes. Endocr Relat Cancer 17:941-951
    • (2010) Endocr Relat Cancer , vol.17 , pp. 941-951
    • Fierz, Y.1    Novosyadlyy, R.2    Vijayakumar, A.3    Yakar, S.4    LeRoith, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.