HDAC6 maintains mitochondrial connectivity under hypoxic stress by suppressing MARCH5/MITOL dependent MFN2 degradation

Biochemical and Biophysical Research Communications

Volumn 464, Issue 4, 2015, Pages 1235-1240

  Kim, Hak June ^a   Nagano, Yoshito ^b   Choi, Su Jin ^a   Park, Song Yi ^a   Kim, Hongtae ^c   Yao, Tso Pang ^d,e   Lee, Joo Yong ^a  

^a Chungnam National University   (South Korea)

^b HIROSHIMA UNIVERSITY   (Japan)

^c Sungkyunkwan University   (South Korea)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

HDAC6; Hypoxia; MARCH5; MFN2; Mitochondrial connectivity

Indexed keywords

HISTONE DEACETYLASE 6; MARCH5 PROTEIN; MITOFUSIN 2; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; GUANOSINE TRIPHOSPHATASE; HDAC6 PROTEIN, MOUSE; HISTONE DEACETYLASE; MARCH5 PROTEIN, MOUSE; MFN2 PROTEIN, MOUSE; MITOCHONDRIAL PROTEIN; MITOL PROTEIN, HUMAN; OXYGEN;

A549 CELL LINE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HYPOXIA; METABOLIC STRESS; MITOCHONDRIAL CONNECTIVITY; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; ANIMAL; CELL HYPOXIA; DOWN REGULATION; METABOLISM; PHYSIOLOGICAL STRESS; PHYSIOLOGY; ULTRASTRUCTURE;

MUS;

ANIMALS; CELL HYPOXIA; DOWN-REGULATION; FEMALE; GTP PHOSPHOHYDROLASES; HISTONE DEACETYLASES; HUMANS; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXYGEN; STRESS, PHYSIOLOGICAL; UBIQUITIN-PROTEIN LIGASES;

EID: 84940461785     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.07.111     Document Type: Article

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