Farming of Plant-Based Veterinary Vaccines and Their Applications for Disease Prevention in Animals

Advances in Virology

Volumn 2015, Issue , 2015, Pages

  Liew, Pit Sze ^a   Hair Bejo, Mohd ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; NEWCASTLE DISEASE VIRUS;

EID: 84940399036     PISSN: 16878639     EISSN: 16878647     Source Type: Journal    
DOI: 10.1155/2015/936940     Document Type: Review

References (88)

1. O. S. Lau and S. S. M. Sun, "Plant seeds as bioreactors for recombinant protein production," Biotechnology Advances, vol. 27, no. 6, pp. 1015-1022, 2009.
2. A.M. Walmsley and C. J. Arntzen, "Plants for delivery of edible vaccines," Current Opinion in Biotechnology, vol. 11, no. 2, pp. 126-129, 2000.
3. E. P. Rybicki, "Plant-produced vaccines: promise and reality," Drug Discovery Today, vol. 14, no. 1-2, pp. 16-24, 2009.
4. L. Santi, "Plant derived veterinary vaccines," Veterinary Research Communications, vol. 33, no. 1, supplement, pp. S61-S66, 2009.
5. J. J. Joensuu, V. Niklander-Teeri, and J. E. Brandle, "Transgenic plants for animal health: plant-made vaccine antigens for animal infectious disease control," Phytochemistry Reviews, vol. 7, no. 3, pp. 553-577, 2008.
6. A. Spk, R. M. Twyman, R. Fischer, J. K. C. Ma, and P. A. C. Sparrow, "Evolution of a regulatory framework for pharmaceuticals derived from genetically modified plants," Trends in Biotechnology, vol. 26, no. 9, pp. 506-517, 2008.
7. G. A. De Zoeten, J. R. Penswick, M. A. Horisberger, P. Ahl, M. Schultze, and T. Hohn, "The expression, localization, and effect of a human interferon in plants," Virology, vol. 172, no. 1, pp. 213-222, 1989.
8. A. Hiatt, R. Cafferkey, andK. Bowdish, "Production of antibodies in transgenic plants," Nature, vol. 342, no. 6245, pp. 76-78, 1989.
9. P. C. Sijmons, B. M. M. Dekker, B. Schrammeijer, T. C. Verwoerd, P. J. M. Van Den Elzen, and A. Hoekema, "Production of correctly processed human serum albumin in transgenic plants," Nature Biotechnology, vol. 8, no. 3, pp. 217-221, 1990.
10. M. Pujol, N. I. Ramez, M. Ayala et al., "An integral approach towards a practical application for a plant-made monoclonal antibody in vaccine purification," Vaccine, vol. 23, no. 15, pp. 1833-1837, 2005.
11. J. K.-C. Ma, E. Barros, R. Bock et al., "Molecular farming for new drugs and vaccines. Current perspectives on the production of pharmaceuticals in transgenic plants,"EMBOReports, vol. 6, no. 7, pp. 593-599, 2005.
12. E. E. Hood, D. R. Witcher, S. Maddock et al., "Commercial production of avidin fromtransgenic maize: characterization of transformant, production, processing, extraction and purification," Molecular Breeding, vol. 3, no. 4, pp. 291-306, 1997.
13. D. R. Witcher, E. E. Hood, D. Peterson et al., "Commercial production of-glucuronidase (GUS): a model system for the production of proteins in plants,"Molecular Breeding, vol. 4, no. 4, pp. 301-312, 1998.
14. S. L. Woodard, J. M. Mayor, M. R. Bailey et al., "Maize (Zea mays)-derived bovine trypsin: characterization of the first large-scale, commercial protein product from transgenic plants," Biotechnology and Applied Biochemistry, vol. 38, no. 2, pp. 123-130, 2003.
15. H. S. Mason, D. M.-K. Lam, and C. J. Arntzen, "Expression of hepatitis B surface antigen in transgenic plants," Proceedings of the National Academy of Sciences of the United States of America, vol. 89, no. 24, pp. 11745-11749, 1992.
16. J. Kapusta, A. Modelska, M. Figlerowicz et al., "A plant-derived edible vaccine against hepatitis B virus," The FASEB Journal, vol. 13, no. 13, pp. 1796-1799, 1999.
17. Y. Thanavala, M. Mahoney, S. Pal et al., "Immunogenicity in humans of an edible vaccine for hepatitis B," Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 9, pp. 3378-3382, 2005.
18. H. S. Mason, T. A. Haq, J. D. Clements, and C. J. Arntzen, "Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): potatoes expressing a synthetic LT-B gene," Vaccine, vol. 16, no. 13, pp. 1336-1343, 1998.
19. C. O. Tacket, M. F. Pasetti, R. Edelman, J. A. Howard, and S. Streatfield, "Immunogenicity of recombinant LT-B delivered orally to humans in transgenic corn," Vaccine, vol. 22, no. 31-32, pp. 4385-4389, 2004.
20. H. S. Mason, J. M. Ball, J.-J. Shi, X. Jiang, M. K. Estes, and C. J. Arntzen, "Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice," Proceedings of the National Academy of Sciences of the United States of America, vol. 93, no. 11, pp. 5335-5340, 1996.
21. P. Vermij and E. Waltz, "USDA approves the first plant-based vaccine," Nature Biotechnology, vol. 24, no. 3, pp. 233-234, 2006.
22. J. K. Ma, "The caries vaccine: a growing prospect," Dental Update, vol. 26, no. 9, pp. 374-380, 1999.
23. D. W. Pascual, "Vaccines are for dinner," Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 26, pp. 10757-10758, 2007.
24. J. Tregoning, P. Maliga, G. Dougan, and P. J. Nixon, "New advances in the production of edible plant vaccines: chloroplast expression of a tetanus vaccine antigen, TetC," Phytochemistry, vol. 65, no. 8, pp. 989-994, 2004.
25. G. J. O'Brien, C. J. Bryant, C. Voogd, H. B. Greenberg, R. C. Gardner, and A. R. Bellamy, "Rotavirus VP6 expressed by PVX vectors in Nicotiana benthamiana coats PVX rods and also assembles into viruslike particles," Virology, vol. 270, no. 2, pp. 444-453, 2000.
26. Z. Huang, I. Dry, D. Webster, R. Strugnell, and S. Wesselingh, "Plant-derived measles virus hemagglutinin protein induces neutralizing antibodies in mice," Vaccine, vol. 19, no. 15-16, pp. 2163-2171, 2001.
27. D. E. Webster, M. L. Cooney, Z. Huang et al., "Successful boosting of a DNA measles immunization with an oral plantderived measles virus vaccine," Journal of Virology, vol. 76, no. 15, pp. 7910-7912, 2002.
28. L. McLain, Z. Durrani, L. A. Wisniewski, C. Porta, G. P. Lomonossoff, and N. J. Dimmock, "Stimulation of neutralizing antibodies to human immunodeficiency virus type 1 in three strains of mice immunized with a 22 amino acid peptide of gp41 expressed on the surface of a plant virus," Vaccine, vol. 14, no. 8, pp. 799-810, 1996.
29. G. G. Zhang, L. Rodrigues, B. Rovinski, and K. A. White, "Production ofHIV-1 p24 protein in transgenic tobacco plants," Applied Biochemistry and Biotechnology-Part B Molecular Biotechnology, vol. 20, no. 2, pp. 131-136, 2002.
30. A. Meyers, E. Chakauya, E. Shephard et al., "Expression of HIV-1 antigens in plants as potential subunit vaccines," BMC Biotechnology, vol. 8, no. 1, article 53, 2008.
31. E. S. Tackaberry, A. K. Dudani, F. Prior et al., "Development of biopharmaceuticals in plant expression systems: cloning, expression and immunological reactivity of human cytomegalovirus glycoprotein B (UL55) in seeds of transgenic tobacco," Vaccine, vol. 17, no. 23-24, pp. 3020-3029, 1999.
32. H. Belanger, N. Fleysh, C. O. X. Shannon et al., "Human respiratory syncytial virus vaccine antigen produced in plants," The FASEB Journal, vol. 14, no. 14, pp. 2323-2328, 2000.
33. J. S. Sandhu, S. F. Krasnyanski, L. L. Domier, S. S. Korban, M. D. Osadjan, and D. E. Buetow, "Oral immunization of mice with transgenic tomato fruit expressing respiratory syncytial virus-F protein induces a systemic immune response," Transgenic Research, vol. 9, no. 2, pp. 127-135, 2000.
34. F. R. Brennan, T. D. Jones, M. Longstaff et al., "Immunogenicity of peptides derived from a fibronectin-binding protein of S. aureus expressed on two different plant viruses," Vaccine, vol. 17, no. 15-16, pp. 1846-1857, 1999.
35. F. R. Brennan, T. D. Jones, L. B. Gilleland et al., "Pseudomonas aeruginosa outer-membrane protein F epitopes are highly immunogenic in mice when expressed on a plant virus," Microbiology, vol. 145, no. 1, pp. 211-220, 1999.
36. J. Staczek, M. Bendahmane, L. B. Gilleland, R.N. Beachy, and H. E. Gilleland Jr., "Immunization with a chimeric tobacco mosaic virus containing an epitope of outer membrane protein F of Pseudomonas aeruginosa provides protection against challenge with P. aeruginosa," Vaccine, vol. 18, no. 21, pp. 2266-2274, 2000.
37. T. H. Turpen, S. J. Reinl, Y. Charoenvit, S. L. Hoffman, V. Fallarme, and L. K. Grill, "Malaria epitopes expressed on the surface of recombinant tobacco mosaic virus," Nature Biotechnology, vol. 13, no. 1, pp. 53-57, 1995.
38. F. Sala, M. M. Rigano, A. Barbante, B. Basso, A. M. Walmsley, and S. Castiglione, "Vaccine antigen production in transgenic plants: strategies, gene constructs and perspectives," Vaccine, vol. 21, no. 7-8, pp. 803-808, 2003.
39. D. M. Floss, D. Falkenburg, and U. Conrad, "Production of vaccines and therapeutic antibodies for veterinary applications in transgenic plants: an overview," Transgenic Research, vol. 16, no. 3, pp. 315-332, 2007.
40. M. M. Rigano and A. M. Walmsley, "Expression systems and developments in plant-made vaccines," Immunology and Cell Biology, vol. 83, no. 3, pp. 271-277, 2005.
41. H. S. Mason, H. Warzecha, T. Mor, and C. J. Arntzen, "Edible plant vaccines: applications for prophylactic and therapeutic molecular medicine," Trends in Molecular Medicine, vol. 8, no. 7, pp. 324-329, 2002.
42. G. Giddings, "Transgenic plants as protein factories," Current Opinion in Biotechnology, vol. 12, no. 5, pp. 450-454, 2001.
43. V. Mett, C. E. Farrance, B. J. Green, and V. Yusibov, "Plants as biofactories," Biologicals, vol. 36, no. 6, pp. 354-358, 2008.
44. J. C. Muskett, N. E. Reed, and D. H. Thornton, "Increased virulence of an infectious bursal disease live virus vaccine after passage in chicks," Vaccine, vol. 3, no. 4, pp. 309-312, 1985.
45. G. Zavala and S. Cheng, "Detection and characterization of avian leukosis virus inMarek's disease vaccines," Avian Diseases, vol. 50, no. 2, pp. 209-215, 2006.
46. S. J. Streatfield and J. A. Howard, "Plant-based vaccines," International Journal for Parasitology, vol. 33, no. 5-6, pp. 479-493, 2003.
47. I. B. H. Wilson, "Glycosylation of proteins in plants and invertebrates," Current Opinion in Structural Biology, vol. 12, no. 5, pp. 569-577, 2002.
48. S. A. Brooks, "Appropriate glycosylation of recombinant proteins for human use,"Molecular Biotechnology, vol. 28, no. 3, pp. 241-255, 2004.
49. C. Saint-Jore-Dupas, L. Faye, and V. Gomord, "From planta to pharma with glycosylation in the toolbox," Trends in Biotechnology, vol. 25, no. 7, pp. 317-323, 2007.
50. R. Fischer, E. Stoger, S. Schillberg, P. Christou, and R. M. Twyman, "Plant-based production of biopharmaceuticals," Current Opinion in Plant Biology, vol. 7, no. 2, pp. 152-158, 2004.
51. Arabidopsis Genome Initiative, "Analysis of the genome sequence of the flowering plant Arabidopsis thaliana," Nature, vol. 408, pp. 796-815, 2000.
52. H. Daniell, S. J. Streatfield, and K. Wycoff, "Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants," Trends in Plant Science, vol. 6, no. 5, pp. 219-226, 2001.
53. R. M. Twyman, E. Stoger, S. Schillberg, P. Christou, and R. Fischer, "Molecular farming in plants: host systems and expression technology," Trends in Biotechnology, vol. 21, no. 12, pp. 570-578, 2003.
54. P. Lerouge, M. Cabanes-Macheteau, C. Rayon, A.-C. Fischette-Lain, V. Gomord, and L. Faye, "N-glycoprotein biosynthesis in plants: recent developments and future trends," PlantMolecular Biology, vol. 38, no. 1-2, pp. 31-48, 1998.
55. V. Gomord, A.-C. Fitchette, L. Menu-Bouaouiche et al., "Plantspecific glycosylation patterns in the context of therapeutic protein production," Plant Biotechnology Journal, vol. 8, no. 5, pp. 564-587, 2010.
56. M. Bardor, C. Loutelier-Bourhis, T. Paccalet et al., "Monoclonal C5-1 antibody produced in transgenic alfalfa plants exhibits a N-glycosylation that is homogenous and suitable for glycoengineering into human-compatible structures," Plant Biotechnology Journal, vol. 1, no. 6, pp. 451-462, 2003.
57. J.-Y. Zhou, J.-X. Wu, L.-Q. Cheng et al., "Expression of immunogenic S1 glycoprotein of infectious bronchitis virus in transgenic potatoes," Journal of Virology, vol. 77, no. 16, pp. 9090-9093, 2003.
58. J.-Y. Zhou, L.-Q. Cheng, X.-J. Zheng et al., "Generation of the transgenic potato expressing full-length spike protein of infectious bronchitis virus," Journal of Biotechnology, vol. 111, no. 2, pp. 121-130, 2004.
59. K. S. Gunn, N. Singh, J. Giambrone, and H. Wu, "Using transgenic plants as bioreactors to produce edible vaccines," Journal of Biotech Research, vol. 4, no. 1, pp. 92-99, 2012.
60. P. B. McGarvey, J. Hammond, M. M. Dienelt et al., "Expression of the rabies virus glycoprotein in transgenic tomatoes," Nature Biotechnology, vol. 13, no. 13, pp. 1484-1487, 1995.
61. S. Saldana, F. E. Guadarrama, T. D. J. Olivera Flores et al., "Production of rotavirus-like particles in tomato (Lycopersicon esculentum L.) fruit by expression of capsid proteins VP2 and VP6 and immunological studies," Viral Immunology, vol. 19, no. 1, pp. 42-53, 2006.
62. J. Boothe, C. Nykiforuk, Y. Shen et al., "Seed-based expression systems for plant molecular farming," Plant Biotechnology Journal, vol. 8, no. 5, pp. 588-606, 2010.
63. E. Stger, C. Vaquero, E. Torres et al., "Cereal crops as viable production and storage systems for pharmaceutical scFv antibodies," Plant Molecular Biology, vol. 42, no. 4, pp. 583-590, 2000.
64. T. Nochi, H. Takagi, Y. Yuki et al., "Rice-based mucosal vaccine as a global strategy for cold-chain-and needle-free vaccination," Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 26, pp. 10986-10991, 2007.
65. K. Ramessar, M. Sabalza, T. Capell, and P. Christou, "Maize plants: an ideal production platform for effective and safe molecular pharming," Plant Science, vol. 174, no. 4, pp. 409-419, 2008.
66. S. J. Streatfield, J. M. Jilka, E. E. Hood et al., "Plant-based vaccines: unique advantages," Vaccine, vol. 19, no. 17-19, pp. 2742-2748, 2001.
67. B. J. Lamphear, J. M. Jilka, L. Kesl, M. Welter, J. A. Howard, and S. J. Streatfield, "A corn-based delivery system for animal vaccines: an oral transmissible gastroenteritis virus vaccine boosts lactogenic immunity in swine," Vaccine, vol. 22, no. 19, pp. 2420-2424, 2004.
68. O. Guerrero-Andrade, E. Loza-Rubio, T. Olivera-Flores, T. Fehrvri-Bone, and M. A. Gmez-Lim, "Expression of the Newcastle disease virus fusion protein in transgenic maize and immunological studies," Transgenic Research, vol. 15, no. 4, pp. 455-463, 2006.
69. J. Wu, L. Yu, L. Li, J. Hu, J. Zhou, and X. Zhou, "Oral immunization with transgenic rice seeds expressing VP2 protein of infectious bursal disease virus induces protective immune responses in chickens," Plant Biotechnology Journal, vol. 5, no. 5, pp. 570-578, 2007.
70. J. J. Joensuu, M. Kotiaho, T. H. Teeri et al., "Glycosylated F4 (K88) fimbrial adhesin FaeG expressed in barley endosperm induces ETEC-neutralizing antibodies in mice," Transgenic Research, vol. 15, no. 3, pp. 359-373, 2006.
71. T. Moravec, M. A. Schmidt, E. M. Herman, and T. Woodford-Thomas, "Production of Escherichia coli heat labile toxin (LT) B subunit in soybean seed and analysis of its immunogenicity as an oral vaccine," Vaccine, vol. 25, no. 9, pp. 1647-1657, 2007.
72. E. Stoger, J. K.-C. Ma, R. Fischer, and P. Christou, "Sowing the seeds of success: pharmaceutical proteins from plants," Current Opinion in Biotechnology, vol. 16, no. 2, pp. 167-173, 2005.
73. K. Dalsgaard, A. Uttentha, T. D. Jones et al., "Plant-derived vaccine protects target animals against a viral disease," Nature Biotechnology, vol. 15, no. 3, pp. 248-252, 1997.
74. S. Castann, M. S. Mar, J. M. Mart-Alonso et al., "Immunization with potato plants expressing VP60 protein protects against rabbit hemorrhagic disease virus," Journal of Virology, vol. 73, no. 5, pp. 4452-4455, 1999.
75. J. M. Mart-Alonso, S. Castann, P. Alonso, F. Parra, and R. Ords, "Oral immunization using tuber extracts from transgenic potato plants expressing rabbit hemorrhagic disease virus capsid protein," Transgenic Research, vol. 12, no. 1, pp. 127-130, 2003.
76. C.-D. Yang, J.-T. Liao, C.-Y. Lai et al., "Induction of protective immunity in swine by recombinant bamboo mosaic virus expressing foot-and-mouth disease virus epitopes," BMC Biotechnology, vol. 7, no. 1, article 62, 2007.
77. T.-H. Chen, T.-H. Chen, C.-C. Hu et al., "Induction of protective immunity in chickens immunized with plant-made chimeric bamboo mosaic virus particles expressing very virulent Infectious bursal disease virus antigen," Virus Research, vol. 166, no. 1-2, pp. 109-115, 2012.
78. E. Gmez, M. S. Lucero, S. Chimeno Zoth, J. M. Carballeda, M. J. Gravisaco, and A. Berinstein, "Transient expression of VP2 in Nicotiana benthamiana and its use as a plant-based vaccine against infectious bursal disease virus," Vaccine, vol. 31, no. 23, pp. 2623-2627, 2013.
79. B. J. Lamphear, S. J. Streatfield, J. M. Jilka et al., "Delivery of subunit vaccines in maize seed," Journal of Controlled Release, vol. 85, no. 1-3, pp. 169-180, 2002.
80. J. A. Howard, "Commercialization of plant-based vaccines from research and development to manufacturing.," Animal Health Research Reviews, vol. 5, no. 2, pp. 243-245, 2004.
81. C. Carrillo, A. Wigdorovitz, J. C. Oliveros et al., "Protective immune response to foot-and-mouth disease virus with VP1 expressed in transgenic plants," Journal of Virology, vol. 72, no. 2, pp. 1688-1690, 1998.
82. A. Wigdorovitz, C. Carrillo, M. J. Dus Santos et al., "Induction of a protective antibody response to foot and mouth disease virus in mice following oral or parenteral immunization with alfalfa transgenic plants expressing the viral structural protein VP1," Virology, vol. 255, no. 2, pp. 347-353, 1999.
83. M. J. D. Santos, A. Wigdorovitz, K. Trono et al., "A novel methodology to develop a foot and mouth disease virus (FMDV) peptide-based vaccine in transgenic plants," Vaccine, vol. 20, no. 7-8, pp. 1141-1147, 2002.
84. C. Carrillo, A. Wigdorovitz, K. Trono et al., "Induction of a virus-specific antibody response to foot and mouth disease virus using the structural protein VP1 expressed in transgenic potato plants," Viral Immunology, vol. 14, no. 1, pp. 49-57, 2001.
85. A. Wigdorovitz, D. M. Prez Filgueira, N. Robertson et al., "Protection of mice against challenge with foot and mouth disease virus (FMDV) by immunization with foliar extracts from plants infected with recombinant tobacco mosaic virus expressing the FMDV structural protein VP1," Virology, vol. 264, no. 1, pp. 85-91, 1999.
86. H. Nick, D. Cursiefen, and H. Becht, "Structural and growth characteristics of infectious bursal disease virus," Journal of Virology, vol. 18, no. 1, pp. 227-234, 1976.
87. H. Wu, N. K. Singh, R. D. Locy, K. Scissum-Gunn, and J. J. Giambrone, "Expression of immunogenic VP2 protein of infectious bursal disease virus inArabidopsis thaliana," Biotechnology Letters, vol. 26, no. 10, pp. 787-792, 2004.
88. H. S. Mason and M. M. Herbst-Kralovetz, "Plant-derived antigens as mucosal vaccines," Current Topics in Microbiology and Immunology, vol. 354, no. 1, pp. 101-120, 2012.