Plant-based vaccines: Unique advantages

Vaccine

Volumn 19, Issue 17-19, 2001, Pages 2742-2748

  Streatfield, Stephen J ^a   Jilka, Joseph M ^a   Hood, Elizabeth E ^a   Turner, Debra D ^b   Bailey, Michele R ^a   Mayor, Jocelyne M ^a   Woodard, Susan L ^a   Beifuss, Katherine K ^a   Horn, Michael E ^a   Delaney, Donna E ^a   Tizard, Ian R ^b   Howard, John A ^a  

^a Prodigene Inc   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Escherichia coli heat labile enterotoxin (LT); Plant vaccines; Transmissible gastroenteritis virus (TGEV)

Indexed keywords

ANTIGEN; BACTERIAL TOXIN; DRUG VEHICLE; EDIBLE VACCINE; ENTEROTOXIN B; EPITOPE; ESCHERICHIA COLI ENTEROTOXIN; LIVE VACCINE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; CONFERENCE PAPER; CONTROLLED STUDY; CORN; CORONAVIRUS; DIARRHEA; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG SAFETY; DRUG STABILITY; ENVIRONMENTAL TEMPERATURE; GASTROENTERITIS; IMMUNE RESPONSE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT SEED; PRIORITY JOURNAL; SWINE; TRANSGENIC PLANT; VACCINE PRODUCTION;

ANIMALS; BACTERIAL TOXINS; BIOTECHNOLOGY; ENTEROTOXINS; ESCHERICHIA COLI PROTEINS; MICE; MICE, INBRED BALB C; PLANTS, GENETICALLY MODIFIED; PLASMIDS; RHIZOBIUM; TRANSFORMATION, GENETIC; TRANSMISSIBLE GASTROENTERITIS VIRUS; VACCINES, SYNTHETIC; VIRAL PROTEINS; ZEA MAYS;

EID: 0035925713     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(00)00512-0     Document Type: Conference Paper

References (22)

1. Expression of hepatitis B surface antigen in transgenic plants
2. Expression of cholera toxin B subunit oligomers in transgenic potato plants
3. Expression of immunogenic glycoprotein S polypeptides from transmissible gastroenteritis coronavirus in transgenic plants
4. Oral immunization with a recombinant bacterial antigen produced in transgenic plants
5. Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice
6. Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): Potatoes expressing a synthetic LT-B gene
7. Efficacy of a food plant-based oral cholera toxin B subunit vaccine
8. Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato
9. Human immune responses to a novel Norwalk virus vaccine delivered in transgenic potatoes
10. The epidemiology of cholera and enterotoxigenic E. coli diarrheal disease
11. Epidemiology of travellers' diarrhea and relative importance of various pathogens
12. Crystal structure of a cholera toxin-related heat-labile enterotoxin from E. coli
13. Oral B-subunit whole-cell vaccines against cholera and enterotoxigenic Escherichia coli diarrhea
14. Double-blind, randomized, placebo controlled pilot study evaluating efficacy and reactogenicity of an oral ETEC B-subunit-inactivated whole cell vaccine against travelers' diarrhea (preliminary report)
15. Molecular biology of transmissible gastroenteritis virus
16. Immunity to transmissible gastroenteritis virus and porcine respiratory coronavirus infections in swine
17. Commercial production of avidin from transgenic maize: Characterization of transformant, production, processing, extraction and purification
18. High efficiency transformation of maize (Zea mays L.) mediated by Agrobacterium tumefaciens
19. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
20. Sealed adult mice: New model for enterotoxin evaluation
21. Features of oral immunization
22. Induction and assessment of immunity at enteromucosal surfaces in humans: Implications for vaccine development