Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice

Frontiers in Genetics

Volumn 6, Issue JUL, 2015, Pages

  Johnson, Simon C ^a,b   Yanos, Melana E ^a   Bitto, Alessandro ^a   Castanza, Anthony ^a   Gagnidze, Arni ^a   Gonzalez, Brenda ^b   Gupta, Kanav ^a   Hui, Jessica ^a   Jarvie, Conner ^a   Johnson, Brittany M ^a   Letexier, Nicolas ^a   McCanta, Lanny ^a   Sangesland, Maya ^a   Tamis, Oliver ^a   Uhde, Lauren ^a   Den Ende, Alex Van ^a   Rabinovitch, Peter S ^a   Suh, Yousin ^b   Kaeberlein, Matt ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Aging; Mitochondrial disease; MTOR; Pharmaceutical intervention; Rapamycin

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN;

AGING; ARTICLE; BLOOD LEVEL; BLOOD SAMPLING; BODY WEIGHT; CONTROLLED STUDY; CORRELATION COEFFICIENT; ENCAPSULATION; GENETIC ANALYSIS; LEIGH DISEASE; MORTALITY; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; WEIGHT GAIN;

MAMMALIA; MURINAE; MUS;

EID: 84940102312     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2015.00247     Document Type: Article

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