Submicron complex lipid carriers for curcumin delivery to intestinal epithelial cells: Effect of different emulsifiers on bioaccessibility and cell uptake

International Journal of Pharmaceutics

Volumn 494, Issue 1, 2015, Pages 357-369

  Yucel, Cigdem ^a,b   Quagliariello, Vincenzo ^c   Iaffaioli, Rosario Vincenzo ^c   Ferrari, Giovanna ^a,b   Donsì, Francesco ^a,d  

^a UNIVERSITY OF SALERNO   (Italy)

^b ProdAl Scarl ^*  (Italy)

^c NATIONAL CANCER INSTITUTE   (Italy)

^d UNILEVER RESEARCH VLAARDINGEN   (Netherlands)

Author keywords

Cell uptake; Curcumin; HT29 cell line; Lipid based carriers; Simulated digestion; Whey protein isolates

Indexed keywords

AMPHOPHILE; CURCUMIN; GLYCEROL OLEATE; MEDIUM CHAIN TRIACYLGLYCEROL; MILK PROTEIN; PALM OIL; POLYSORBATE 20; STARCH; SUNFLOWER OIL; VEGETABLE OIL; WATER; DRUG CARRIER; EMULSIFYING AGENT; LIPID; POLYSORBATE; WHEY PROTEIN;

ARTICLE; BIODEGRADATION; CELL ADHESION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIGESTION; DISPERSION; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG UPTAKE; ENCAPSULATION; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; INTESTINE EPITHELIUM CELL; MOUTH; NANOFABRICATION; PARTICLE SIZE; PRIORITY JOURNAL; STOMACH; BIOAVAILABILITY; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; DRUG STABILITY; EPITHELIUM CELL; HT 29 CELL LINE; INTESTINE; METABOLISM;

BIOLOGICAL AVAILABILITY; CELL SURVIVAL; CURCUMIN; DIGESTION; DRUG CARRIERS; DRUG STABILITY; EMULSIFYING AGENTS; EPITHELIAL CELLS; HT29 CELLS; HUMANS; INTESTINES; LIPIDS; PARTICLE SIZE; PLANT OILS; POLYSORBATES; STARCH; WHEY PROTEINS;

EID: 84940092870     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.08.039     Document Type: Article

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