The mucosal adjuvant cyclic di-AMP exerts immune stimulatory effects on dendritic cells and macrophages

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Škrnjug, Ivana ^a   Rueckert, Christine ^a   Libanova, Rimma ^a,b   Lienenklaus, Stefan ^a   Weiss, Siegfried ^a   Guzmán, Carlos A ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b Boehringer Ingelheim Veterinary Research Center GmbH and Co KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE PHOSPHATE; BETA INTERFERON; CONCANAVALIN A; CYCLIC DINUCLEOTIDE BIS (39,59) CYCLIC DIMERIC ADENOSINE MONOPHOSPHATE; IMMUNOLOGICAL ADJUVANT; UNCLASSIFIED DRUG; CYCLIC DIADENOSINE PHOSPHATE; DINUCLEOSIDE PHOSPHATE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL SUBPOPULATION; CELL SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; FEMALE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE ACTIVATION; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; T LYMPHOCYTE ACTIVATION; TARGET CELL; UPREGULATION; ANIMAL; BIOSYNTHESIS; CYTOLOGY; DRUG EFFECTS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; LYMPHOID TISSUE; MACROPHAGE; METABOLISM; MUCOSA; T LYMPHOCYTE SUBPOPULATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; COSTIMULATORY AND INHIBITORY T-CELL RECEPTORS; DENDRITIC CELLS; DINUCLEOSIDE PHOSPHATES; FEMALE; HUMANS; INTERFERON-BETA; LYMPHOCYTE ACTIVATION; LYMPHOID TISSUE; MACROPHAGES; MICE; MUCOUS MEMBRANE; T-LYMPHOCYTE SUBSETS;

EID: 84899717979     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0095728     Document Type: Article

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