-
1
-
-
70350716934
-
The perplexing functions and surprising origins of Legionella pneumophila type IV secretion effectors
-
Franco I.S., Shuman H.A., Charpentier X. The perplexing functions and surprising origins of Legionella pneumophila type IV secretion effectors. Cell. Microbiol. 2009, 11:1435-1443.
-
(2009)
Cell. Microbiol.
, vol.11
, pp. 1435-1443
-
-
Franco, I.S.1
Shuman, H.A.2
Charpentier, X.3
-
2
-
-
34547217380
-
Effector proteins translocated by Legionella pneumophila: strength in numbers
-
Ninio S., Roy C.R. Effector proteins translocated by Legionella pneumophila: strength in numbers. Trends Microbiol. 2007, 15:372-380.
-
(2007)
Trends Microbiol.
, vol.15
, pp. 372-380
-
-
Ninio, S.1
Roy, C.R.2
-
3
-
-
33847183077
-
Cooperation of Toll-like receptor signals in innate immune defence
-
Trinchieri G., Sher A. Cooperation of Toll-like receptor signals in innate immune defence. Nat. Rev. Immunol. 2007, 7:179-190.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 179-190
-
-
Trinchieri, G.1
Sher, A.2
-
4
-
-
74549167783
-
Regulation of adaptive immunity by the innate immune system
-
Iwasaki A., Medzhitov R. Regulation of adaptive immunity by the innate immune system. Science 2010, 327:291-295.
-
(2010)
Science
, vol.327
, pp. 291-295
-
-
Iwasaki, A.1
Medzhitov, R.2
-
5
-
-
79951679142
-
Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses
-
Barber G.N. Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses. Curr. Opin. Immunol. 2011, 23:10-20.
-
(2011)
Curr. Opin. Immunol.
, vol.23
, pp. 10-20
-
-
Barber, G.N.1
-
6
-
-
77957745555
-
Type I interferon: friend or foe?
-
Trinchieri G. Type I interferon: friend or foe?. J. Exp. Med. 2010, 207:2053-2063.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2053-2063
-
-
Trinchieri, G.1
-
7
-
-
71049179767
-
Interferons direct an effective innate response to Legionella pneumophila infection
-
Plumlee C.R., Lee C., Beg A.A., Decker T., Shuman H.A., Schindler C. Interferons direct an effective innate response to Legionella pneumophila infection. J. Biol. Chem. 2009, 284:30058-30066.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 30058-30066
-
-
Plumlee, C.R.1
Lee, C.2
Beg, A.A.3
Decker, T.4
Shuman, H.A.5
Schindler, C.6
-
8
-
-
3142705098
-
Type I IFN protects permissive macrophages from Legionella pneumophila infection through an IFN-gamma-independent pathway
-
Schiavoni G., Mauri C., Carlei D., Belardelli F., Pastoris M.C., Proietti E. Type I IFN protects permissive macrophages from Legionella pneumophila infection through an IFN-gamma-independent pathway. J. Immunol. 2004, 173:1266-1275.
-
(2004)
J. Immunol.
, vol.173
, pp. 1266-1275
-
-
Schiavoni, G.1
Mauri, C.2
Carlei, D.3
Belardelli, F.4
Pastoris, M.C.5
Proietti, E.6
-
9
-
-
34548406570
-
Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways
-
Coers J., Vance R.E., Fontana M.F., Dietrich W.F. Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways. Cell. Microbiol. 2007, 9:2344-2357.
-
(2007)
Cell. Microbiol.
, vol.9
, pp. 2344-2357
-
-
Coers, J.1
Vance, R.E.2
Fontana, M.F.3
Dietrich, W.F.4
-
10
-
-
67651091732
-
Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system
-
Vance R.E., Isberg R.R., Portnoy D.A. Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system. Cell Host Microbe 2009, 6:10-21.
-
(2009)
Cell Host Microbe
, vol.6
, pp. 10-21
-
-
Vance, R.E.1
Isberg, R.R.2
Portnoy, D.A.3
-
11
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
Kanneganti T.D., Ozoren N., Body-Malapel M., Amer A., Park J.H., Franchi L., Whitfield J., Barchet W., Colonna M., Vandenabeele P., Bertin J., Coyle A., Grant E.P., Akira S., Nunez G. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 2006, 440:233-236.
-
(2006)
Nature
, vol.440
, pp. 233-236
-
-
Kanneganti, T.D.1
Ozoren, N.2
Body-Malapel, M.3
Amer, A.4
Park, J.H.5
Franchi, L.6
Whitfield, J.7
Barchet, W.8
Colonna, M.9
Vandenabeele, P.10
Bertin, J.11
Coyle, A.12
Grant, E.P.13
Akira, S.14
Nunez, G.15
-
12
-
-
30444450839
-
Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
-
Stetson D.B., Medzhitov R. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity 2006, 24:93-103.
-
(2006)
Immunity
, vol.24
, pp. 93-103
-
-
Stetson, D.B.1
Medzhitov, R.2
-
13
-
-
73549090166
-
Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila
-
Monroe K.M., McWhirter S.M., Vance R.E. Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila. PLoS Pathog. 2009, 5:e1000665.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Monroe, K.M.1
McWhirter, S.M.2
Vance, R.E.3
-
14
-
-
68049092912
-
RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway
-
Chiu Y.H., Macmillan J.B., Chen Z.J. RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell 2009, 138:576-591.
-
(2009)
Cell
, vol.138
, pp. 576-591
-
-
Chiu, Y.H.1
Macmillan, J.B.2
Chen, Z.J.3
-
15
-
-
79251506939
-
The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the invivo interferon response to Listeria monocytogenes and cyclic dinucleotides
-
Sauer J.D., Sotelo-Troha K., von Moltke J., Monroe K.M., Rae C.S., Brubaker S.W., Hyodo M., Hayakawa Y., Woodward J.J., Portnoy D.A., Vance R.E. The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the invivo interferon response to Listeria monocytogenes and cyclic dinucleotides. Infect. Immun 2011, 79:688-694.
-
(2011)
Infect. Immun
, vol.79
, pp. 688-694
-
-
Sauer, J.D.1
Sotelo-Troha, K.2
von Moltke, J.3
Monroe, K.M.4
Rae, C.S.5
Brubaker, S.W.6
Hyodo, M.7
Hayakawa, Y.8
Woodward, J.J.9
Portnoy, D.A.10
Vance, R.E.11
-
16
-
-
67651125824
-
A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP
-
McWhirter S.M., Barbalat R., Monroe K.M., Fontana M.F., Hyodo M., Joncker N.T., Ishii K.J., Akira S., Colonna M., Chen Z.J., Fitzgerald K.A., Hayakawa Y., Vance R.E. A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP. J. Exp. Med. 2009, 206:1899-1911.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1899-1911
-
-
McWhirter, S.M.1
Barbalat, R.2
Monroe, K.M.3
Fontana, M.F.4
Hyodo, M.5
Joncker, N.T.6
Ishii, K.J.7
Akira, S.8
Colonna, M.9
Chen, Z.J.10
Fitzgerald, K.A.11
Hayakawa, Y.12
Vance, R.E.13
-
17
-
-
77954070545
-
C-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response
-
Woodward J.J., Iavarone A.T., Portnoy D.A. c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response. Science 2010, 328:1703-1705.
-
(2010)
Science
, vol.328
, pp. 1703-1705
-
-
Woodward, J.J.1
Iavarone, A.T.2
Portnoy, D.A.3
-
18
-
-
63049137897
-
Principles of c-di-GMP signalling in bacteria
-
Hengge R. Principles of c-di-GMP signalling in bacteria. Nat. Rev. Microbiol. 2009, 7:263-273.
-
(2009)
Nat. Rev. Microbiol.
, vol.7
, pp. 263-273
-
-
Hengge, R.1
-
19
-
-
33846916451
-
Bacterial c-di-GMP is an immunostimulatory molecule
-
Karaolis D.K., Means T.K., Yang D., Takahashi M., Yoshimura T., Muraille E., Philpott D., Schroeder J.T., Hyodo M., Hayakawa Y., Talbot B.G., Brouillette E., Malouin F. Bacterial c-di-GMP is an immunostimulatory molecule. J. Immunol. 2007, 178:2171-2181.
-
(2007)
J. Immunol.
, vol.178
, pp. 2171-2181
-
-
Karaolis, D.K.1
Means, T.K.2
Yang, D.3
Takahashi, M.4
Yoshimura, T.5
Muraille, E.6
Philpott, D.7
Schroeder, J.T.8
Hyodo, M.9
Hayakawa, Y.10
Talbot, B.G.11
Brouillette, E.12
Malouin, F.13
-
20
-
-
77954933973
-
3',5'-Cyclic diguanylic acid: a small nucleotide that makes big impacts
-
Yan H., Chen W. 3',5'-Cyclic diguanylic acid: a small nucleotide that makes big impacts. Chem. Soc. Rev. 2010, 39:2914-2924.
-
(2010)
Chem. Soc. Rev.
, vol.39
, pp. 2914-2924
-
-
Yan, H.1
Chen, W.2
-
21
-
-
79955085332
-
Cyclic diguanylate signaling proteins control intracellular growth of Legionella pneumophila
-
Levi A., Folcher M., Jenal U., Shuman H.A. Cyclic diguanylate signaling proteins control intracellular growth of Legionella pneumophila. mBio 2011, 2:e00316-10.
-
(2011)
mBio
, vol.2
-
-
Levi, A.1
Folcher, M.2
Jenal, U.3
Shuman, H.A.4
-
22
-
-
43049087389
-
Structural biochemistry of a bacterial checkpoint protein reveals diadenylate cyclase activity regulated by DNA recombination intermediates
-
Witte G., Hartung S., Buttner K., Hopfner K.P. Structural biochemistry of a bacterial checkpoint protein reveals diadenylate cyclase activity regulated by DNA recombination intermediates. Mol. Cell 2008, 30:167-178.
-
(2008)
Mol. Cell
, vol.30
, pp. 167-178
-
-
Witte, G.1
Hartung, S.2
Buttner, K.3
Hopfner, K.P.4
-
23
-
-
75549090603
-
The Pfam protein families database
-
Finn R.D., Mistry J., Tate J., Coggill P., Heger A., Pollington J.E., Gavin O.L., Gunasekaran P., Ceric G., Forslund K., Holm L., Sonnhammer E.L., Eddy S.R., Bateman A. The Pfam protein families database. Nucleic Acids Res. 2010, 38:D211-D222.
-
(2010)
Nucleic Acids Res.
, vol.38
-
-
Finn, R.D.1
Mistry, J.2
Tate, J.3
Coggill, P.4
Heger, A.5
Pollington, J.E.6
Gavin, O.L.7
Gunasekaran, P.8
Ceric, G.9
Forslund, K.10
Holm, L.11
Sonnhammer, E.L.12
Eddy, S.R.13
Bateman, A.14
-
24
-
-
34250856229
-
Stat2-dependent regulation of MHC class II expression
-
Zhao W., Cha E.N., Lee C., Park C.Y., Schindler C. Stat2-dependent regulation of MHC class II expression. J. Immunol. 2007, 179:463-471.
-
(2007)
J. Immunol.
, vol.179
, pp. 463-471
-
-
Zhao, W.1
Cha, E.N.2
Lee, C.3
Park, C.Y.4
Schindler, C.5
-
25
-
-
0022401274
-
Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirus
-
Blasi E., Mathieson B.J., Varesio L., Cleveland J.L., Borchert P.A., Rapp U.R. Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirus. Nature 1985, 318:667-670.
-
(1985)
Nature
, vol.318
, pp. 667-670
-
-
Blasi, E.1
Mathieson, B.J.2
Varesio, L.3
Cleveland, J.L.4
Borchert, P.A.5
Rapp, U.R.6
-
26
-
-
78649258448
-
Convenient synthesis of a propargylated cyclic (3'-5') diguanylic Acid and its "click" conjugation to a biotinylated azide
-
Grajkowski A., Cieslak J., Gapeev A., Schindler C., Beaucage S.L. Convenient synthesis of a propargylated cyclic (3'-5') diguanylic Acid and its "click" conjugation to a biotinylated azide. Bioconjug. Chem. 2010, 21:2147-2152.
-
(2010)
Bioconjug. Chem.
, vol.21
, pp. 2147-2152
-
-
Grajkowski, A.1
Cieslak, J.2
Gapeev, A.3
Schindler, C.4
Beaucage, S.L.5
-
27
-
-
79953056071
-
A semisynthetic Eph receptor tyrosine kinase provides insight into ligand- induced kinase activation
-
Singla N., Erdjument-Bromage H., Himanen J.P., Muir T.W., Nikolov D.B. A semisynthetic Eph receptor tyrosine kinase provides insight into ligand- induced kinase activation. Chem. Biol. 2011, 18:361-371.
-
(2011)
Chem. Biol.
, vol.18
, pp. 361-371
-
-
Singla, N.1
Erdjument-Bromage, H.2
Himanen, J.P.3
Muir, T.W.4
Nikolov, D.B.5
-
28
-
-
77955953184
-
Cyclic di-GMP signaling regulates invasion by Ehrlichia chaffeensis of human monocytes
-
Kumagai Y., Matsuo J., Hayakawa Y., Rikihisa Y. Cyclic di-GMP signaling regulates invasion by Ehrlichia chaffeensis of human monocytes. J. Bacteriol. 2010, 192:4122-4133.
-
(2010)
J. Bacteriol.
, vol.192
, pp. 4122-4133
-
-
Kumagai, Y.1
Matsuo, J.2
Hayakawa, Y.3
Rikihisa, Y.4
-
29
-
-
33745736151
-
Recognition and delivery of effector proteins into eukaryotic cells by bacterial secretion systems
-
Cambronne E.D., Roy C.R. Recognition and delivery of effector proteins into eukaryotic cells by bacterial secretion systems. Traffic 2006, 7:929-939.
-
(2006)
Traffic
, vol.7
, pp. 929-939
-
-
Cambronne, E.D.1
Roy, C.R.2
-
30
-
-
33846014297
-
Critical role for cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
-
Kanneganti T.D., Body-Malapel M., Amer A., Park J.H., Whitfield J., Taraporewala Z.F., Miller D., Patton J.T., Inohara N., Nunez G. Critical role for cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J. Biol. Chem. 2006, 281:36560-36568.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 36560-36568
-
-
Kanneganti, T.D.1
Body-Malapel, M.2
Amer, A.3
Park, J.H.4
Whitfield, J.5
Taraporewala, Z.F.6
Miller, D.7
Patton, J.T.8
Inohara, N.9
Nunez, G.10
-
31
-
-
79959242498
-
Detection of prokaryotic mRNA signifies microbial viability and promotes immunity
-
Sander L.E., Davis M.J., Boekschoten M.V., Amsen D., Dascher C.C., Ryffel B., Swanson J.A., Muller M., Blander J.M. Detection of prokaryotic mRNA signifies microbial viability and promotes immunity. Nature 2011, 474:385-389.
-
(2011)
Nature
, vol.474
, pp. 385-389
-
-
Sander, L.E.1
Davis, M.J.2
Boekschoten, M.V.3
Amsen, D.4
Dascher, C.C.5
Ryffel, B.6
Swanson, J.A.7
Muller, M.8
Blander, J.M.9
-
32
-
-
79959630000
-
Expanding TRAF function: TRAF3 as a tri-faced immune regulator
-
Hacker H., Tseng P.H., Karin M. Expanding TRAF function: TRAF3 as a tri-faced immune regulator. Nat. Rev. Immunol. 2011, 11:457-468.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 457-468
-
-
Hacker, H.1
Tseng, P.H.2
Karin, M.3
|