Hyperinduction of host beta interferon by a Listeria monocytogenes strain naturally overexpressing the multidrug efflux pump MdrT

Infection and Immunity

Volumn 80, Issue 4, 2012, Pages 1537-1545

  Schwartz, Kierstyn T ^a   Carleton, Joshua D ^a   Quillin, Sarah J ^a   Rollins, Stuart D ^a   Portnoy, Daniel A ^b   Leber, Jess H ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BETA INTERFERON; BRTA PROTEIN; MULTIDRUG RESISTANCE PROTEIN; UNCLASSIFIED DRUG; BIS(3',5') CYCLIC DIGUANYLIC ACID; BIS(3',5')-CYCLIC DIGUANYLIC ACID; CARRIER PROTEIN; CYCLIC GMP; DRUG DERIVATIVE;

ALLELE; ANIMAL CELL; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; CLONE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME REPRESSION; GENE OVEREXPRESSION; GENETIC ANALYSIS; IN VIVO STUDY; LISTERIA MONOCYTOGENES; LOSS OF FUNCTION MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; DNA SEQUENCE; GENE; GENETICS; IMMUNOLOGY; MACROPHAGE; METABOLISM; MICROBIOLOGY; NUCLEOTIDE SEQUENCE; PATHOGENICITY;

ANIMALS; BACTERIAL PROTEINS; BASE SEQUENCE; CELLS, CULTURED; CYCLIC GMP; GENES, MDR; INTERFERON-BETA; LISTERIA MONOCYTOGENES; MACROPHAGES; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED C57BL; SEQUENCE ANALYSIS, DNA;

EID: 84860788934     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.06286-11     Document Type: Article

References (42)

1. Auerbuch V, Brockstedt DG, Meyer-Morse N, O'Riordan M, Portnoy DA. 2004. Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes. J. Exp. Med. 200:527-533.
2. Aureli P, et al. 2000. An outbreak of febrile gastroenteritis associated with corn contaminated by Listeria monocytogenes. N. Engl. J. Med. 342:1236-1241.
3. Begley M, Gahan CG, Hill C. 2002. Bile stress response in Listeria mono-cytogenes LO28: adaptation, cross-protection, and identification of genetic loci involved in bile resistance. Appl. Environ. Microbiol. 68:6005- 6012.
4. Begley M, Hill C, Gahan CG. 2003. Identification and disruption of btlA, a locus involved in bile tolerance and general stress resistance in Listeria monocytogenes. FEMS Microbiol. Lett. 218:31-38.
5. Begley M, Kerr C, Hill C. 2009. Exposure to bile influences biofilm formation by Listeria monocytogenes. Gut Pathog. 1:11.
6. Begley M, Sleator RD, Gahan CG, Hill C. 2005. Contribution of three bile-associated loci, bsh, pva, and btlB, to gastrointestinal persistence and bile tolerance of Listeria monocytogenes. Infect. Immun. 73:894 -904.
7. Burdette DL, et al. 2011. STING is a direct innate immune sensor of cyclic di-GMP. Nature 478:515-518.
8. Carrero JA, Calderon B, Unanue ER. 2004. Type I interferon sensitizes lymphocytes to apoptosis and reduces resistance to Listeria infection. J. Exp. Med. 200:535-540.
9. CDC. 1989. Listeriosis associated with consumption of turkey franks. MMWR Morb. Mortal. Wkly. Rep. 38:267-268.
10. CDC. 1998. Multistate outbreak of listeriosis-United States, 1998. MMWR Morb. Mortal. Wkly. Rep. 47:1085-1086.
11. Crimmins GT, et al. 2008. Listeria monocytogenes multidrug resistance transporters activate a cytosolic surveillance pathway of innate immunity. Proc. Natl. Acad. Sci. U. S. A. 105:10191-10196.
12. Edman DC, Pollock MB, Hall ER. 1968. Listeria monocytogenes L forms. I. Induction, maintenance, and biological characteristics. J. Bacteriol. 96: 352-357.
13. Glaser P, et al. 2001. Comparative genomics of Listeria species. Science 294:849-852.
14. Gray MJ, et al. 2004. Listeria monocytogenes isolates from foods and humans form distinct but overlapping populations. Appl. Environ. Microbiol. 70:5833-5841.
15. Haque A, et al. 2011. Type I interferons suppress CD4 T-cell-dependent parasite control during blood-stage Plasmodium infection. Eur. J. Immunol. 41:2688-2698.
16. Jonquieres R, Bierne H, Mengaud J, Cossart P. 1998. The inlA gene of Listeria monocytogenes LO28 harbors a nonsense mutation resulting in release of internalin. Infect. Immun. 66:3420-3422.
17. Leber JH, et al. 2008. Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen. PLoS Pathog. 4:e6.
18. Lecuit M, et al. 1999. A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes. EMBO J. 18:3956-3963.
19. Lecuit M, et al. 2001. A transgenic model for listeriosis: role of internalin in crossing the intestinal barrier. Science 292:1722-1725.
20. Lyon GJ, Novick RP. 2004. Peptide signaling in Staphylococcus aureus and other Gram-positive bacteria. Peptides 25:1389-1403.
21. Manca C, et al. 2005. Hypervirulent M. tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak-Stat pathway. J. Interferon Cytokine Res. 25:694-701.
22. Maniatis T, et al. 1998. Structure and function of the interferon-beta enhanceosome. Cold Spring Harb. Symp. Quant. Biol. 63:609-620.
23. Mascola L, Lieb L, Chiu J, Fannin SL, Linnan MJ. 1988. Listeriosis: an uncommon opportunistic infection in patients with acquired immunodeficiency syndrome. A report of five cases and a review of the literature. Am. J. Med. 84:162-164.
24. McCaffrey RL, et al. 2004. A specific gene expression program triggered by Gram-positive bacteria in the cytosol. Proc. Natl. Acad. Sci. U. S. A. 101:11386-11391.
25. Monk IR, Casey PG, Cronin M, Gahan CGM, Hill C. 2008. Development of multiple strain competitive index assays for Listeria monocytogenes using pIMC, a new site-specific intergrative vector. BMC Microbiol. 8:96. doi:10.1186/1471-2180-8-96.
26. O'Connell RM, et al. 2004. Type I interferon production enhances susceptibility to Listeria monocytogenes infection. J. Exp. Med. 200:437-445.
27. O'Riordan M, Yi CH, Gonzales R, Lee KD, Portnoy DA. 2002. Innate recognition of bacteria by a macrophage cytosolic surveillance pathway. Proc. Natl. Acad. Sci. U. S. A. 99:13861-13866.
28. Portnoy DA, Chakraborty T, Goebel W, Cossart P. 1992. Molecular determinants of Listeria monocytogenes pathogenesis. Infect. Immun. 60: 1263-1267.
29. Quillin SJ, Schwartz KT, Leber JH. 2011. The novel Listeria monocytogenes bile sensor BrtA controls expression of the cholic acid efflux pump MdrT. Mol. Microbiol. 81:129-142.
30. Ramos JL, et al. 2005. The TetR family of transcriptional repressors. Microbiol. Mol. Biol. Rev. 69:326-356.
31. Rayamajhi M, Humann J, Penheiter K, Andreasen K, Lenz LL. 2010. Induction of IFN-αβ enables Listeria monocytogenes to suppress macrophage activation by IFN-γ. J. Exp. Med. 207:327-337.
32. Reutterer B, et al. 2008. Type I IFN are host modulators of strain-specific Listeria monocytogenes virulence. Cell. Microbiol. 10:1116-1129.
33. Riedel CU, et al. 2009. AgrD-dependent quorum sensing affects biofilm formation, invasion, virulence and global gene expression profiles in Listeria monocytogenes. Mol. Microbiol. 71:1177-1189.
34. Romling U. 2008. Great times for small molecules: c-di-AMP, a second messenger candidate in Bacteria and Archaea. Sci. Signal. 1:pe39.
35. Sauer JD, et al. 2011. The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides. Infect. Immun. 79:688-694.
36. Stanley SA, Johndrow JE, Manzanillo P, Cox JS. 2007. The type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis. J. Immunol. 178: 3143-3152.
37. Stockinger S, et al. 2004. IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR- and Nod2-independent mechanism. J. Immunol. 173:7416-7425.
38. Van Bambeke F, Balzi E, Tulkens PM. 2000. Antibiotic efflux pumps. Biochem. Pharmacol. 60:457-470.
39. Vazquez-Boland JA, et al. 2001. Listeria pathogenesis and molecular virulence determinants. Clin. Microbiol. Rev. 14:584-640.
40. Vicente MF, Baquero F, Perez-Diaz JC. 1985. Cloning and expression of the Listeria monocytogenes haemolysin in Escherichia coli. FEMS Microbiology Lett. 30:77-79.
41. Wiedmann M, et al. 1997. Ribotypes and virulence gene polymorphisms suggest three distinct Listeria monocytogenes lineages with differences in pathogenic potential. Infect. Immun. 65:2707-2716.
42. Woodward JJ, Iavarone AT, Portnoy DA. 2010. c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response. Science 328:1703-1705.