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Volumn 40, Issue 6, 2014, Pages 652-659

Plasminogen activator inhibitor-1 in aging

Author keywords

fibrosis; metabolic syndrome; PAI 1; thrombosis; vascular sclerosis

Indexed keywords

PLASMINOGEN ACTIVATOR INHIBITOR 1;

EID: 84939884913     PISSN: 00946176     EISSN: 10989064     Source Type: Journal    
DOI: 10.1055/s-0034-1384635     Document Type: Article
Times cited : (56)

References (100)
  • 1
    • 0026591870 scopus 로고
    • Thrombosis and cardiovascular risk in the elderly
    • Tracy R. P., Bovill E. G. Thrombosis and cardiovascular risk in the elderly. Arch Pathol Lab Med: 1992; 116 12 1307 1312
    • (1992) Arch Pathol Lab Med , vol.116 , Issue.12 , pp. 1307-1312
    • Tracy, R.P.1    Bovill, E.G.2
  • 3
    • 0033055408 scopus 로고    scopus 로고
    • The natural course of atherosclerosis. Part II: Vascular remodeling
    • Kiechl S., Willeit J.; Bruneck Study Group. The natural course of atherosclerosis. Part II: vascular remodeling. Arterioscler Thromb Vasc Biol: 1999; 19 6 1491 1498
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , Issue.6 , pp. 1491-1498
    • Kiechl, S.1    Willeit, J.2
  • 4
    • 0028342850 scopus 로고
    • Factor VII and fibrinogen levels as risk factors for venous thrombosis. A case-control study of plasma levels and DNA polymorphisms-the Leiden Thrombophilia Study (LETS)
    • Koster T., Rosendaal F. R., Reitsma P. H., van der Velden P. A., Briët E., Vandenbroucke J. P. Factor VII and fibrinogen levels as risk factors for venous thrombosis. A case-control study of plasma levels and DNA polymorphisms-the Leiden Thrombophilia Study (LETS). Thromb Haemost: 1994; 71 6 719 722
    • (1994) Thromb Haemost , vol.71 , Issue.6 , pp. 719-722
    • Koster, T.1    Rosendaal, F.R.2    Reitsma, P.H.3    Van Der Velden, P.A.4    Briët, E.5    Vandenbroucke, J.P.6
  • 7
    • 0024568021 scopus 로고
    • In: Coller B. ed. Progress in Hemostasis and Thrombosis Philadelphia, PA WB Saunders Company
    • Loskutoff D. J., Sawdey M., Mimuro J. Type 1 plasminogen activator inhibitor. In: Coller B., ed. Progress in Hemostasis and Thrombosis. Philadelphia, PA WB Saunders Company: 1988; 87 115
    • (1988) Type 1 Plasminogen Activator Inhibitor , pp. 87-115
    • Loskutoff, D.J.1    Sawdey, M.2    Mimuro, J.3
  • 8
    • 0031742314 scopus 로고    scopus 로고
    • A pathological role of increased expression of plasminogen activator inhibitor-1 in human or animal disorders
    • Yamamoto K., Saito H. A pathological role of increased expression of plasminogen activator inhibitor-1 in human or animal disorders. Int J Hematol: 1998; 68 4 371 385
    • (1998) Int J Hematol , vol.68 , Issue.4 , pp. 371-385
    • Yamamoto, K.1    Saito, H.2
  • 9
    • 16344393174 scopus 로고    scopus 로고
    • Aging and plasminogen activator inhibitor-1 (PAI-1) regulation: Implication in the pathogenesis of thrombotic disorders in the elderly
    • Yamamoto K., Takeshita K., Kojima T., Takamatsu J., Saito H. Aging and plasminogen activator inhibitor-1 (PAI-1) regulation: implication in the pathogenesis of thrombotic disorders in the elderly. Cardiovasc Res: 2005; 66 276 285
    • (2005) Cardiovasc Res , vol.66 , pp. 276-285
    • Yamamoto, K.1    Takeshita, K.2    Kojima, T.3    Takamatsu, J.4    Saito, H.5
  • 10
    • 0029745109 scopus 로고    scopus 로고
    • The serpin PAI-1 inhibits cell migration by blocking integrin alpha v beta 3 binding to vitronectin
    • Stefansson S., Lawrence D. A. The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin. Nature: 1996; 383 6599 441 443
    • (1996) Nature , vol.383 , Issue.6599 , pp. 441-443
    • Stefansson, S.1    Lawrence, D.A.2
  • 11
    • 0032826035 scopus 로고    scopus 로고
    • Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure
    • Heymans S., Luttun A., Nuyens D., et al. Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure. Nat Med: 1999; 5 10 1135 1142
    • (1999) Nat Med , vol.5 , Issue.10 , pp. 1135-1142
    • Heymans, S.1    Luttun, A.2    Nuyens, D.3
  • 12
    • 34250694859 scopus 로고    scopus 로고
    • Reactive site-dependent phenotypic alterations in plasminogen activator inhibitor-1 transgenic mice
    • Eren M., Gleaves L. A., Atkinson J. B., King L. E., Declerck P. J., Vaughan D. E. Reactive site-dependent phenotypic alterations in plasminogen activator inhibitor-1 transgenic mice. J Thromb Haemost: 2007; 5 7 1500 1508
    • (2007) J Thromb Haemost , vol.5 , Issue.7 , pp. 1500-1508
    • Eren, M.1    Gleaves, L.A.2    Atkinson, J.B.3    King, L.E.4    Declerck, P.J.5    Vaughan, D.E.6
  • 13
    • 0025946943 scopus 로고
    • Regulation of PAI-1 gene expression
    • Loskutoff D. J. Regulation of PAI-1 gene expression. Fibrinolysis: 1991; 5 197 206
    • (1991) Fibrinolysis , vol.5 , pp. 197-206
    • Loskutoff, D.J.1
  • 14
    • 0025949379 scopus 로고
    • Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-α, and transforming growth factor-β
    • Sawdey M. S., Loskutoff D. J. Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-α, and transforming growth factor-β J Clin Invest: 1991; 88 4 1346 1353
    • (1991) J Clin Invest , vol.88 , Issue.4 , pp. 1346-1353
    • Sawdey, M.S.1    Loskutoff, D.J.2
  • 15
    • 0029888356 scopus 로고    scopus 로고
    • Fibrin deposition in tissues from endotoxin-treated mice correlates with decreases in the expression of urokinase-type but not tissue-type plasminogen activator
    • Yamamoto K., Loskutoff D. J. Fibrin deposition in tissues from endotoxin-treated mice correlates with decreases in the expression of urokinase-type but not tissue-type plasminogen activator. J Clin Invest: 1996; 97 11 2440 2451
    • (1996) J Clin Invest , vol.97 , Issue.11 , pp. 2440-2451
    • Yamamoto, K.1    Loskutoff, D.J.2
  • 16
    • 0030050952 scopus 로고    scopus 로고
    • Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor- α and lipopolysaccharide
    • Samad F., Yamamoto K., Loskutoff D. J. Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor- α and lipopolysaccharide. J Clin Invest: 1996; 97 1 37 46
    • (1996) J Clin Invest , vol.97 , Issue.1 , pp. 37-46
    • Samad, F.1    Yamamoto, K.2    Loskutoff, D.J.3
  • 17
    • 0037154259 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 is a major stress-regulated gene: Implications for stress-induced thrombosis in aged individuals
    • Yamamoto K., Takeshita K., Shimokawa T., et al. Plasminogen activator inhibitor-1 is a major stress-regulated gene: implications for stress-induced thrombosis in aged individuals. Proc Natl Acad Sci U S A: 2002; 99 2 890 895
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.2 , pp. 890-895
    • Yamamoto, K.1    Takeshita, K.2    Shimokawa, T.3
  • 18
    • 1542289735 scopus 로고    scopus 로고
    • Increased expression of plasminogen activator inhibitor-1 in cardiomyocytes contributes to cardiac fibrosis after myocardial infarction
    • Takeshita K., Hayashi M., Iino S., et al. Increased expression of plasminogen activator inhibitor-1 in cardiomyocytes contributes to cardiac fibrosis after myocardial infarction. Am J Pathol: 2004; 164 2 449 456
    • (2004) Am J Pathol , vol.164 , Issue.2 , pp. 449-456
    • Takeshita, K.1    Hayashi, M.2    Iino, S.3
  • 19
    • 0026646590 scopus 로고
    • Substrate-bound fibrinogen, fibrin and other cell attachment-promoting proteins as a scaffold for cultured vascular smooth muscle cells
    • Naito M., Funaki C., Hayashi T., et al. Substrate-bound fibrinogen, fibrin and other cell attachment-promoting proteins as a scaffold for cultured vascular smooth muscle cells. Atherosclerosis: 1992; 96 2-3 227 234
    • (1992) Atherosclerosis , vol.96 , Issue.23 , pp. 227-234
    • Naito, M.1    Funaki, C.2    Hayashi, T.3
  • 20
    • 0025147158 scopus 로고
    • Factors influencing the accumulation in fibrous plaques of lipid derived from low density lipoprotein. II. Preferential immobilization of lipoprotein (a) (Lp(a))
    • Smith E. B., Cochran S. Factors influencing the accumulation in fibrous plaques of lipid derived from low density lipoprotein. II. Preferential immobilization of lipoprotein (a) (Lp(a)). Atherosclerosis: 1990; 84 2-3 173 181
    • (1990) Atherosclerosis , vol.84 , Issue.23 , pp. 173-181
    • Smith, E.B.1    Cochran, S.2
  • 21
    • 0034672348 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 deficiency protects against atherosclerosis progression in the mouse carotid artery
    • Eitzman D. T., Westrick R. J., Xu Z., Tyson J., Ginsburg D. Plasminogen activator inhibitor-1 deficiency protects against atherosclerosis progression in the mouse carotid artery. Blood: 2000; 96 13 4212 4215
    • (2000) Blood , vol.96 , Issue.13 , pp. 4212-4215
    • Eitzman, D.T.1    Westrick, R.J.2    Xu, Z.3    Tyson, J.4    Ginsburg, D.5
  • 22
    • 44449098793 scopus 로고    scopus 로고
    • Progression of symptomatic intracranial large artery atherosclerosis is associated with a proinflammatory state and impaired fibrinolysis
    • Arenillas J. F., Alvarez-Sabín J., Molina C. A., et al. Progression of symptomatic intracranial large artery atherosclerosis is associated with a proinflammatory state and impaired fibrinolysis. Stroke: 2008; 39 5 1456 1463
    • (2008) Stroke , vol.39 , Issue.5 , pp. 1456-1463
    • Arenillas, J.F.1    Alvarez-Sabín, J.2    Molina, C.A.3
  • 23
    • 0025734531 scopus 로고
    • Increased plasma plasminogen activator inhibitor 1 levels. A possible link between insulin resistance and atherothrombosis
    • Juhan-Vague I., Alessi M. C., Vague P. Increased plasma plasminogen activator inhibitor 1 levels. A possible link between insulin resistance and atherothrombosis. Diabetologia: 1991; 34 7 457 462
    • (1991) Diabetologia , vol.34 , Issue.7 , pp. 457-462
    • Juhan-Vague, I.1    Alessi, M.C.2    Vague, P.3
  • 24
    • 0026650622 scopus 로고
    • Increased type 1 plasminogen activator inhibitor gene expression in atherosclerotic human arteries
    • Schneiderman J., Sawdey M. S., Keeton M. R., et al. Increased type 1 plasminogen activator inhibitor gene expression in atherosclerotic human arteries. Proc Natl Acad Sci U S A: 1992; 89 15 6998 7002
    • (1992) Proc Natl Acad Sci U S A , vol.89 , Issue.15 , pp. 6998-7002
    • Schneiderman, J.1    Sawdey, M.S.2    Keeton, M.R.3
  • 25
    • 0028260690 scopus 로고
    • Plasminogen activator inhibitor-1 expression in human liver and healthy or atherosclerotic vessel walls
    • Chomiki N., Henry M., Alessi M. C., Anfosso F., Juhan-Vague I. Plasminogen activator inhibitor-1 expression in human liver and healthy or atherosclerotic vessel walls. Thromb Haemost: 1994; 72 1 44 53
    • (1994) Thromb Haemost , vol.72 , Issue.1 , pp. 44-53
    • Chomiki, N.1    Henry, M.2    Alessi, M.C.3    Anfosso, F.4    Juhan-Vague, I.5
  • 26
    • 0029921312 scopus 로고    scopus 로고
    • Molecular markers of senescence in fibroblast-like cultures
    • Cristofalo V. J., Pignolo R. J. Molecular markers of senescence in fibroblast-like cultures. Exp Gerontol: 1996; 31 1-2 111 123
    • (1996) Exp Gerontol , vol.31 , Issue.12 , pp. 111-123
    • Cristofalo, V.J.1    Pignolo, R.J.2
  • 27
    • 34548186667 scopus 로고    scopus 로고
    • Cellular senescence: When bad things happen to good cells
    • Campisi J., d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol: 2007; 8 9 729 740
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.9 , pp. 729-740
    • Campisi, J.1    D'Adda Di Fagagna, F.2
  • 28
    • 0033752717 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor type 1 is a potential target in renal fibrogenesis
    • Rerolle J. P., Hertig A., Nguyen G., Sraer J. D., Rondeau E. P. Plasminogen activator inhibitor type 1 is a potential target in renal fibrogenesis. Kidney Int: 2000; 58 5 1841 1850
    • (2000) Kidney Int , vol.58 , Issue.5 , pp. 1841-1850
    • Rerolle, J.P.1    Hertig, A.2    Nguyen, G.3    Sraer, J.D.4    Rondeau, E.P.5
  • 29
    • 0031049715 scopus 로고    scopus 로고
    • Modulation of plasminogen activator inhibitor-1 in vivo: A new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition
    • Oikawa T., Freeman M., Lo W., Vaughan D. E., Fogo A. Modulation of plasminogen activator inhibitor-1 in vivo: a new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition. Kidney Int: 1997; 51 1 164 172
    • (1997) Kidney Int , vol.51 , Issue.1 , pp. 164-172
    • Oikawa, T.1    Freeman, M.2    Lo, W.3    Vaughan, D.E.4    Fogo, A.5
  • 30
    • 0030882822 scopus 로고    scopus 로고
    • The kidneys of mice with autoimmune disease acquire a hypofibrinolytic/procoagulant state that correlates with the development of glomerulonephritis and tissue microthrombosis
    • Yamamoto K., Loskutoff D. J. The kidneys of mice with autoimmune disease acquire a hypofibrinolytic/procoagulant state that correlates with the development of glomerulonephritis and tissue microthrombosis. Am J Pathol: 1997; 151 3 725 734
    • (1997) Am J Pathol , vol.151 , Issue.3 , pp. 725-734
    • Yamamoto, K.1    Loskutoff, D.J.2
  • 31
    • 20244388950 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition attenuates hypofibrinolysis and reduces cardiac perivascular fibrosis in genetically obese diabetic mice
    • Zaman A. K., Fujii S., Sawa H., et al. Angiotensin-converting enzyme inhibition attenuates hypofibrinolysis and reduces cardiac perivascular fibrosis in genetically obese diabetic mice. Circulation: 2001; 103 25 3123 3128
    • (2001) Circulation , vol.103 , Issue.25 , pp. 3123-3128
    • Zaman, A.K.1    Fujii, S.2    Sawa, H.3
  • 32
    • 0035859783 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 deficiency prevents hypertension and vascular fibrosis in response to long-term nitric oxide synthase inhibition
    • Kaikita K., Fogo A. B., Ma L., Schoenhard J. A., Brown N. J., Vaughan D. E. Plasminogen activator inhibitor-1 deficiency prevents hypertension and vascular fibrosis in response to long-term nitric oxide synthase inhibition. Circulation: 2001; 104 7 839 844
    • (2001) Circulation , vol.104 , Issue.7 , pp. 839-844
    • Kaikita, K.1    Fogo, A.B.2    Ma, L.3    Schoenhard, J.A.4    Brown, N.J.5    Vaughan, D.E.6
  • 33
    • 0023197175 scopus 로고
    • Urokinase-type plasminogen activator: Proenzyme, receptor, and inhibitors
    • Blasi F., Vassalli J. D., Dano K. Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitors. J Cell Biol: 1987; 104 4 801 804
    • (1987) J Cell Biol , vol.104 , Issue.4 , pp. 801-804
    • Blasi, F.1    Vassalli, J.D.2    Dano, K.3
  • 34
    • 0029118192 scopus 로고
    • Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse
    • Olman M. A., Mackman N., Gladson C. L., Moser K. M., Loskutoff D. J. Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse. J Clin Invest: 1995; 96 3 1621 1630
    • (1995) J Clin Invest , vol.96 , Issue.3 , pp. 1621-1630
    • Olman, M.A.1    Mackman, N.2    Gladson, C.L.3    Moser, K.M.4    Loskutoff, D.J.5
  • 35
    • 0030054203 scopus 로고    scopus 로고
    • Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene
    • Eitzman D. T., McCoy R. D., Zheng X., et al. Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene. J Clin Invest: 1996; 97 1 232 237
    • (1996) J Clin Invest , vol.97 , Issue.1 , pp. 232-237
    • Eitzman, D.T.1    McCoy, R.D.2    Zheng, X.3
  • 36
    • 0028912882 scopus 로고
    • Angiotensin II regulates the expression of plasminogen activator inhibitor-1 in cultured endothelial cells. A potential link between the renin-angiotensin system and thrombosis
    • Vaughan D. E., Lazos S. A., Tong K. Angiotensin II regulates the expression of plasminogen activator inhibitor-1 in cultured endothelial cells. A potential link between the renin-angiotensin system and thrombosis. J Clin Invest: 1995; 95 3 995 1001
    • (1995) J Clin Invest , vol.95 , Issue.3 , pp. 995-1001
    • Vaughan, D.E.1    Lazos, S.A.2    Tong, K.3
  • 37
    • 0042878465 scopus 로고    scopus 로고
    • Pleiotropic effects of angiotensin II receptor blocker in hypertensive patients
    • Koh K. K., Ahn J. Y., Han S. H., et al. Pleiotropic effects of angiotensin II receptor blocker in hypertensive patients. J Am Coll Cardiol: 2003; 42 5 905 910
    • (2003) J Am Coll Cardiol , vol.42 , Issue.5 , pp. 905-910
    • Koh, K.K.1    Ahn, J.Y.2    Han, S.H.3
  • 38
    • 4344603861 scopus 로고    scopus 로고
    • Bradykinin decreases plasminogen activator inhibitor-1 expression and facilitates matrix degradation in the renal tubulointerstitium under angiotensin-converting enzyme blockade
    • Okada H., Watanabe Y., Kikuta T., et al. Bradykinin decreases plasminogen activator inhibitor-1 expression and facilitates matrix degradation in the renal tubulointerstitium under angiotensin-converting enzyme blockade. J Am Soc Nephrol: 2004; 15 9 2404 2413
    • (2004) J Am Soc Nephrol , vol.15 , Issue.9 , pp. 2404-2413
    • Okada, H.1    Watanabe, Y.2    Kikuta, T.3
  • 39
    • 0032407095 scopus 로고    scopus 로고
    • Effect of activation and inhibition of the renin-angiotensin system on plasma PAI-1
    • Brown N. J., Agirbasli M. A., Williams G. H., Litchfield W. R., Vaughan D. E. Effect of activation and inhibition of the renin-angiotensin system on plasma PAI-1. Hypertension: 1998; 32 6 965 971
    • (1998) Hypertension , vol.32 , Issue.6 , pp. 965-971
    • Brown, N.J.1    Agirbasli, M.A.2    Williams, G.H.3    Litchfield, W.R.4    Vaughan, D.E.5
  • 40
    • 0035955754 scopus 로고    scopus 로고
    • ENOS activity is reduced in senescent human endothelial cells: Preservation by hTERT immortalization
    • Matsushita H., Chang E., Glassford A. J., Cooke J. P., Chiu C. P., Tsao P. S. eNOS activity is reduced in senescent human endothelial cells: Preservation by hTERT immortalization. Circ Res: 2001; 89 9 793 798
    • (2001) Circ Res , vol.89 , Issue.9 , pp. 793-798
    • Matsushita, H.1    Chang, E.2    Glassford, A.J.3    Cooke, J.P.4    Chiu, C.P.5    Tsao, P.S.6
  • 41
    • 33750944018 scopus 로고    scopus 로고
    • Endothelial cellular senescence is inhibited by nitric oxide: Implications in atherosclerosis associated with menopause and diabetes
    • Hayashi T., Matsui-Hirai H., Miyazaki-Akita A., et al. Endothelial cellular senescence is inhibited by nitric oxide: implications in atherosclerosis associated with menopause and diabetes. Proc Natl Acad Sci U S A: 2006; 103 45 17018 17023
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.45 , pp. 17018-17023
    • Hayashi, T.1    Matsui-Hirai, H.2    Miyazaki-Akita, A.3
  • 42
    • 0031797874 scopus 로고    scopus 로고
    • Natriuretic factors and nitric oxide suppress plasminogen activator inhibitor-1 expression in vascular smooth muscle cells. Role of cGMP in the regulation of the plasminogen system
    • Bouchie J. L., Hansen H., Feener E. P. Natriuretic factors and nitric oxide suppress plasminogen activator inhibitor-1 expression in vascular smooth muscle cells. Role of cGMP in the regulation of the plasminogen system. Arterioscler Thromb Vasc Biol: 1998; 18 11 1771 1779
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , Issue.11 , pp. 1771-1779
    • Bouchie, J.L.1    Hansen, H.2    Feener, E.P.3
  • 43
    • 0033955769 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitor prevents plasminogen activator inhibitor-1 expression in a rat model with cardiovascular remodeling induced by chronic inhibition of nitric oxide synthesis
    • Katoh M., Egashira K., Mitsui T., Chishima S., Takeshita A., Narita H. Angiotensin-converting enzyme inhibitor prevents plasminogen activator inhibitor-1 expression in a rat model with cardiovascular remodeling induced by chronic inhibition of nitric oxide synthesis. J Mol Cell Cardiol: 2000; 32 1 73 83
    • (2000) J Mol Cell Cardiol , vol.32 , Issue.1 , pp. 73-83
    • Katoh, M.1    Egashira, K.2    Mitsui, T.3    Chishima, S.4    Takeshita, A.5    Narita, H.6
  • 44
    • 13244268628 scopus 로고    scopus 로고
    • Pharmacological inhibition and genetic deficiency of plasminogen activator inhibitor-1 attenuates angiotensin II/salt-induced aortic remodeling
    • Weisberg A. D., Albornoz F., Griffin J. P., et al. Pharmacological inhibition and genetic deficiency of plasminogen activator inhibitor-1 attenuates angiotensin II/salt-induced aortic remodeling. Arterioscler Thromb Vasc Biol: 2005; 25 2 365 371
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , Issue.2 , pp. 365-371
    • Weisberg, A.D.1    Albornoz, F.2    Griffin, J.P.3
  • 45
    • 84888206541 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 antagonist TM5441 attenuates Nω-nitro-L-arginine methyl ester-induced hypertension and vascular senescence
    • Boe A. E., Eren M., Murphy S. B., et al. Plasminogen activator inhibitor-1 antagonist TM5441 attenuates Nω-nitro-L-arginine methyl ester-induced hypertension and vascular senescence. Circulation: 2013; 128 21 2318 2324
    • (2013) Circulation , vol.128 , Issue.21 , pp. 2318-2324
    • Boe, A.E.1    Eren, M.2    Murphy, S.B.3
  • 46
    • 0029805074 scopus 로고    scopus 로고
    • Fibrinolytic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. ECAT Study Group. European Concerted Action on Thrombosis and Disabilities
    • Juhan-Vague I., Pyke S. D., Alessi M. C., Jespersen J., Haverkate F., Thompson S. G. Fibrinolytic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. ECAT Study Group. European Concerted Action on Thrombosis and Disabilities. Circulation: 1996; 94 9 2057 2063
    • (1996) Circulation , vol.94 , Issue.9 , pp. 2057-2063
    • Juhan-Vague, I.1    Pyke, S.D.2    Alessi, M.C.3    Jespersen, J.4    Haverkate, F.5    Thompson, S.G.6
  • 47
    • 0022354051 scopus 로고
    • Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction
    • Hamsten A., Wiman B., de Faire U., Blombäck M. Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction. N Engl J Med: 1985; 313 25 1557 1563
    • (1985) N Engl J Med , vol.313 , Issue.25 , pp. 1557-1563
    • Hamsten, A.1    Wiman, B.2    De Faire, U.3    Blombäck, M.4
  • 48
    • 0023185776 scopus 로고
    • Plasminogen activator inhibitor in plasma: Risk factor for recurrent myocardial infarction
    • Hamsten A., de Faire U., Walldius G., et al. Plasminogen activator inhibitor in plasma: risk factor for recurrent myocardial infarction. Lancet: 1987; 2 8549 3 9
    • (1987) Lancet , vol.2 , Issue.8549 , pp. 3-9
    • Hamsten, A.1    De Faire, U.2    Walldius, G.3
  • 49
    • 0042093744 scopus 로고    scopus 로고
    • Acute release of plasminogen activator inhibitor-1 in ST-segment elevation myocardial infarction predicts mortality
    • Collet J. P., Montalescot G., Vicaut E., et al. Acute release of plasminogen activator inhibitor-1 in ST-segment elevation myocardial infarction predicts mortality. Circulation: 2003; 108 4 391 394
    • (2003) Circulation , vol.108 , Issue.4 , pp. 391-394
    • Collet, J.P.1    Montalescot, G.2    Vicaut, E.3
  • 50
    • 84888121848 scopus 로고    scopus 로고
    • Type 1 plasminogen activator inhibitor as a common risk factor for cancer and ischaemic vascular disease: The EPICOR study
    • Iacoviello L., Agnoli C., De Curtis A., et al. Type 1 plasminogen activator inhibitor as a common risk factor for cancer and ischaemic vascular disease: the EPICOR study. BMJ Open: 2013; 3 11 e003725
    • (2013) BMJ Open , vol.3 , Issue.11 , pp. e003725
    • Iacoviello, L.1    Agnoli, C.2    De Curtis, A.3
  • 51
    • 0028901713 scopus 로고
    • Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarction
    • Eriksson P., Kallin B., van 't Hooft F. M., Båvenholm P., Hamsten A. Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarction. Proc Natl Acad Sci U S A: 1995; 92 6 1851 1855
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.6 , pp. 1851-1855
    • Eriksson, P.1    Kallin, B.2    Van 'T Hooft, F.M.3    Båvenholm, P.4    Hamsten, A.5
  • 52
    • 77951904498 scopus 로고    scopus 로고
    • Potentiating effect of endothelial cells on astrocytic plasminogen activator inhibitor type-1 gene expression in an in vitro model of the blood-brain barrier
    • Hultman K., Björklund U., Hansson E., Jern C. Potentiating effect of endothelial cells on astrocytic plasminogen activator inhibitor type-1 gene expression in an in vitro model of the blood-brain barrier. Neuroscience: 2010; 166 2 408 415
    • (2010) Neuroscience , vol.166 , Issue.2 , pp. 408-415
    • Hultman, K.1    Björklund, U.2    Hansson, E.3    Jern, C.4
  • 53
    • 25144460038 scopus 로고    scopus 로고
    • Effects of plasminogen activator inhibitor-1 on ischemic brain injury in permanent and thrombotic middle cerebral artery occlusion models in mice
    • Nagai N., Suzuki Y., Van Hoef B., Lijnen H. R., Collen D. Effects of plasminogen activator inhibitor-1 on ischemic brain injury in permanent and thrombotic middle cerebral artery occlusion models in mice. J Thromb Haemost: 2005; 3 7 1379 1384
    • (2005) J Thromb Haemost , vol.3 , Issue.7 , pp. 1379-1384
    • Nagai, N.1    Suzuki, Y.2    Van Hoef, B.3    Lijnen, H.R.4    Collen, D.5
  • 54
    • 84866733521 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 and thrombotic cerebrovascular diseases
    • Tjärnlund-Wolf A., Brogren H., Lo E. H., Wang X. Plasminogen activator inhibitor-1 and thrombotic cerebrovascular diseases. Stroke: 2012; 43 10 2833 2839
    • (2012) Stroke , vol.43 , Issue.10 , pp. 2833-2839
    • Tjärnlund-Wolf, A.1    Brogren, H.2    Lo, E.H.3    Wang, X.4
  • 55
    • 78650787293 scopus 로고    scopus 로고
    • Autocrine and paracrine up-regulation of blood-brain barrier function by plasminogen activator inhibitor-1
    • Dohgu S., Takata F., Matsumoto J., et al. Autocrine and paracrine up-regulation of blood-brain barrier function by plasminogen activator inhibitor-1. Microvasc Res: 2011; 81 1 103 107
    • (2011) Microvasc Res , vol.81 , Issue.1 , pp. 103-107
    • Dohgu, S.1    Takata, F.2    Matsumoto, J.3
  • 56
    • 57349155023 scopus 로고    scopus 로고
    • Anti-apoptotic roles of plasminogen activator inhibitor-1 as a neurotrophic factor in the central nervous system
    • Soeda S., Koyanagi S., Kuramoto Y., et al. Anti-apoptotic roles of plasminogen activator inhibitor-1 as a neurotrophic factor in the central nervous system. Thromb Haemost: 2008; 100 6 1014 1020
    • (2008) Thromb Haemost , vol.100 , Issue.6 , pp. 1014-1020
    • Soeda, S.1    Koyanagi, S.2    Kuramoto, Y.3
  • 57
    • 0028008336 scopus 로고
    • Factors responsible for impaired fibrinolysis in obese subjects and NIDDM patients
    • McGill J. B., Schneider D. J., Arfken C. L., Lucore C. L., Sobel B. E. Factors responsible for impaired fibrinolysis in obese subjects and NIDDM patients. Diabetes: 1994; 43 1 104 109
    • (1994) Diabetes , vol.43 , Issue.1 , pp. 104-109
    • McGill, J.B.1    Schneider, D.J.2    Arfken, C.L.3    Lucore, C.L.4    Sobel, B.E.5
  • 58
    • 0022625882 scopus 로고
    • Correlation between blood fibrinolytic activity, plasminogen activator inhibitor level, plasma insulin level, and relative body weight in normal and obese subjects
    • Vague P., Juhan-Vague I., Aillaud M. F., et al. Correlation between blood fibrinolytic activity, plasminogen activator inhibitor level, plasma insulin level, and relative body weight in normal and obese subjects. Metabolism: 1986; 35 3 250 253
    • (1986) Metabolism , vol.35 , Issue.3 , pp. 250-253
    • Vague, P.1    Juhan-Vague, I.2    Aillaud, M.F.3
  • 59
    • 48049113447 scopus 로고    scopus 로고
    • Plasma PAI-1 levels are independently related to fatty liver and hypertriglyceridemia in familial combined hyperlipidemia, involvement of apolipoprotein e
    • Brouwers M. C., Govers-Riemslag J., Schalkwijk C. G., et al. Plasma PAI-1 levels are independently related to fatty liver and hypertriglyceridemia in familial combined hyperlipidemia, involvement of apolipoprotein E. Thromb Res: 2008; 122 4 466 472
    • (2008) Thromb Res , vol.122 , Issue.4 , pp. 466-472
    • Brouwers, M.C.1    Govers-Riemslag, J.2    Schalkwijk, C.G.3
  • 60
    • 15844381594 scopus 로고    scopus 로고
    • Enhanced expression of PAI-1 in visceral fat: Possible contributor to vascular disease in obesity
    • Shimomura I., Funahashi T., Takahashi M., et al. Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nat Med: 1996; 2 7 800 803
    • (1996) Nat Med , vol.2 , Issue.7 , pp. 800-803
    • Shimomura, I.1    Funahashi, T.2    Takahashi, M.3
  • 61
    • 0036230414 scopus 로고    scopus 로고
    • Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: The insulin resistance atherosclerosis study
    • Festa A., D'Agostino R. Jr, Tracy R. P., Haffner S. M.; Insulin Resistance Atherosclerosis Study. Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: the insulin resistance atherosclerosis study. Diabetes: 2002; 51 4 1131 1137
    • (2002) Diabetes , vol.51 , Issue.4 , pp. 1131-1137
    • Festa, A.1    Agostino, R.2    Tracy, R.P.3    Haffner, S.M.4
  • 62
    • 0029827134 scopus 로고    scopus 로고
    • Tissue distribution and regulation of plasminogen activator inhibitor-1 in obese mice
    • Samad F., Loskutoff D. J. Tissue distribution and regulation of plasminogen activator inhibitor-1 in obese mice. Mol Med: 1996; 2 5 568 582
    • (1996) Mol Med , vol.2 , Issue.5 , pp. 568-582
    • Samad, F.1    Loskutoff, D.J.2
  • 63
    • 10744228409 scopus 로고    scopus 로고
    • Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1
    • Ma L. J., Mao S. L., Taylor K. L., et al. Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1. Diabetes: 2004; 53 2 336 346
    • (2004) Diabetes , vol.53 , Issue.2 , pp. 336-346
    • Ma, L.J.1    Mao, S.L.2    Taylor, K.L.3
  • 64
    • 0036145255 scopus 로고    scopus 로고
    • Hyperglycemia induces PAI-1 gene expression in adipose tissue by activation of the hexosamine biosynthetic pathway
    • Gabriely I., Yang X. M., Cases J. A., Ma X. H., Rossetti L., Barzilai N. Hyperglycemia induces PAI-1 gene expression in adipose tissue by activation of the hexosamine biosynthetic pathway. Atherosclerosis: 2002; 160 1 115 122
    • (2002) Atherosclerosis , vol.160 , Issue.1 , pp. 115-122
    • Gabriely, I.1    Yang, X.M.2    Cases, J.A.3    Ma, X.H.4    Rossetti, L.5    Barzilai, N.6
  • 65
    • 0034252457 scopus 로고    scopus 로고
    • Insulin continues to induce plasminogen activator inhibitor 1 gene expression in insulin-resistant mice and adipocytes
    • Samad F., Pandey M., Bell P. A., Loskutoff D. J. Insulin continues to induce plasminogen activator inhibitor 1 gene expression in insulin-resistant mice and adipocytes. Mol Med: 2000; 6 8 680 692
    • (2000) Mol Med , vol.6 , Issue.8 , pp. 680-692
    • Samad, F.1    Pandey, M.2    Bell, P.A.3    Loskutoff, D.J.4
  • 66
    • 80051783566 scopus 로고    scopus 로고
    • Profibrinolytic, antithrombotic, and antiinflammatory effects of an insulin-sensitizing strategy in patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial
    • BARI 2D Investigators.
    • Sobel B. E., Hardison R. M., Genuth S., et al. BARI 2D Investigators. Profibrinolytic, antithrombotic, and antiinflammatory effects of an insulin-sensitizing strategy in patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial. Circulation: 2011; 124 6 695 703
    • (2011) Circulation , vol.124 , Issue.6 , pp. 695-703
    • Sobel, B.E.1    Hardison, R.M.2    Genuth, S.3
  • 67
    • 77249132284 scopus 로고    scopus 로고
    • Adipose tissue inflammation in obesity and metabolic syndrome
    • Nishimura S., Manabe I., Nagai R. Adipose tissue inflammation in obesity and metabolic syndrome. Discov Med: 2009; 8 41 55 60
    • (2009) Discov Med , vol.8 , Issue.41 , pp. 55-60
    • Nishimura, S.1    Manabe, I.2    Nagai, R.3
  • 68
    • 84861861951 scopus 로고    scopus 로고
    • Stress augments insulin resistance and prothrombotic state: Role of visceral adipose-derived monocyte chemoattractant protein-1
    • Uchida Y., Takeshita K., Yamamoto K., et al. Stress augments insulin resistance and prothrombotic state: role of visceral adipose-derived monocyte chemoattractant protein-1. Diabetes: 2012; 61 6 1552 1561
    • (2012) Diabetes , vol.61 , Issue.6 , pp. 1552-1561
    • Uchida, Y.1    Takeshita, K.2    Yamamoto, K.3
  • 69
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance
    • Hotamisligil G. S., Arner P., Caro J. F., Atkinson R. L., Spiegelman B. M. Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance. J Clin Invest: 1995; 95 5 2409 2415
    • (1995) J Clin Invest , vol.95 , Issue.5 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3    Atkinson, R.L.4    Spiegelman, B.M.5
  • 70
    • 0033536053 scopus 로고    scopus 로고
    • Tumor necrosis factor α is a key component in the obesity-linked elevation of plasminogen activator inhibitor 1
    • Samad F., Uysal K. T., Wiesbrock S. M., Pandey M., Hotamisligil G. S., Loskutoff D. J. Tumor necrosis factor α is a key component in the obesity-linked elevation of plasminogen activator inhibitor 1. Proc Natl Acad Sci U S A: 1999; 96 12 6902 6907
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.12 , pp. 6902-6907
    • Samad, F.1    Uysal, K.T.2    Wiesbrock, S.M.3    Pandey, M.4    Hotamisligil, G.S.5    Loskutoff, D.J.6
  • 71
    • 0031000588 scopus 로고    scopus 로고
    • Elevated expression of transforming growth factor-β in adipose tissue from obese mice
    • Samad F., Yamamoto K., Pandey M., Loskutoff D. J. Elevated expression of transforming growth factor-β in adipose tissue from obese mice. Mol Med: 1997; 3 1 37 48
    • (1997) Mol Med , vol.3 , Issue.1 , pp. 37-48
    • Samad, F.1    Yamamoto, K.2    Pandey, M.3    Loskutoff, D.J.4
  • 72
    • 0024308313 scopus 로고
    • Plasminogen activator inhibitor 1: A new prognostic marker in septic shock
    • Pralong G., Calandra T., Glauser M-P., et al. Plasminogen activator inhibitor 1: a new prognostic marker in septic shock. Thromb Haemost: 1989; 61 3 459 462
    • (1989) Thromb Haemost , vol.61 , Issue.3 , pp. 459-462
    • Pralong, G.1    Calandra, T.2    Glauser, M.-P.3
  • 73
    • 0036172514 scopus 로고    scopus 로고
    • The tissue factor and plasminogen activator inhibitor type-1 response in pediatric sepsis-induced multiple organ failure
    • Green J., Doughty L., Kaplan S. S., Sasser H., Carcillo J. A. The tissue factor and plasminogen activator inhibitor type-1 response in pediatric sepsis-induced multiple organ failure. Thromb Haemost: 2002; 87 2 218 223
    • (2002) Thromb Haemost , vol.87 , Issue.2 , pp. 218-223
    • Green, J.1    Doughty, L.2    Kaplan, S.S.3    Sasser, H.4    Carcillo, J.A.5
  • 74
    • 0026734184 scopus 로고
    • On the fibrinolytic system in aged rats, and its reactivity to endotoxin and cytokines
    • Emeis J. J., Brouwer A., Barelds R. J., Horan M. A., Durham S. K., Kooistra T. On the fibrinolytic system in aged rats, and its reactivity to endotoxin and cytokines. Thromb Haemost: 1992; 67 6 697 701
    • (1992) Thromb Haemost , vol.67 , Issue.6 , pp. 697-701
    • Emeis, J.J.1    Brouwer, A.2    Barelds, R.J.3    Horan, M.A.4    Durham, S.K.5    Kooistra, T.6
  • 75
    • 0036841486 scopus 로고    scopus 로고
    • Aging accelerates endotoxin-induced thrombosis: Increased responses of plasminogen activator inhibitor-1 and lipopolysaccharide signaling with aging
    • Yamamoto K., Shimokawa T., Yi H., et al. Aging accelerates endotoxin-induced thrombosis: increased responses of plasminogen activator inhibitor-1 and lipopolysaccharide signaling with aging. Am J Pathol: 2002; 161 5 1805 1814
    • (2002) Am J Pathol , vol.161 , Issue.5 , pp. 1805-1814
    • Yamamoto, K.1    Shimokawa, T.2    Yi, H.3
  • 76
    • 0034781712 scopus 로고    scopus 로고
    • Augmented age-associated innate immune responses contribute to negative inotropic and lusitropic effects of lipopolysaccharide and interferon gamma
    • Rosas G. O., Zieman S. J., Donabedian M., Vandegaer K., Hare J. M. Augmented age-associated innate immune responses contribute to negative inotropic and lusitropic effects of lipopolysaccharide and interferon gamma. J Mol Cell Cardiol: 2001; 33 10 1849 1859
    • (2001) J Mol Cell Cardiol , vol.33 , Issue.10 , pp. 1849-1859
    • Rosas, G.O.1    Zieman, S.J.2    Donabedian, M.3    Vandegaer, K.4    Hare, J.M.5
  • 77
    • 0025993463 scopus 로고
    • Elevated plasminogen activator inhibitor levels found in patients with malignant conditions
    • Newland J. R., Haire W. D. Elevated plasminogen activator inhibitor levels found in patients with malignant conditions. Am J Clin Pathol: 1991; 96 5 602 604
    • (1991) Am J Clin Pathol , vol.96 , Issue.5 , pp. 602-604
    • Newland, J.R.1    Haire, W.D.2
  • 78
    • 0025122368 scopus 로고
    • The c-myc-regulated gene mrl encodes plasminogen activator inhibitor 1
    • Prendergast G. C., Diamond L. E., Dahl D., Cole M. D. The c-myc-regulated gene mrl encodes plasminogen activator inhibitor 1. Mol Cell Biol: 1990; 10 3 1265 1269
    • (1990) Mol Cell Biol , vol.10 , Issue.3 , pp. 1265-1269
    • Prendergast, G.C.1    Diamond, L.E.2    Dahl, D.3    Cole, M.D.4
  • 79
    • 15244345941 scopus 로고    scopus 로고
    • The MET oncogene drives a genetic programme linking cancer to haemostasis
    • Boccaccio C., Sabatino G., Medico E., et al. The MET oncogene drives a genetic programme linking cancer to haemostasis. Nature: 2005; 434 7031 396 400
    • (2005) Nature , vol.434 , Issue.7031 , pp. 396-400
    • Boccaccio, C.1    Sabatino, G.2    Medico, E.3
  • 80
    • 0025319263 scopus 로고
    • Plasminogen activator inhibitor-type 1 in Lewis lung carcinoma
    • Kristensen P., Pyke C., Lund L. R., Andreasen P. A., Dano K. Plasminogen activator inhibitor-type 1 in Lewis lung carcinoma. Histochemistry: 1990; 93 6 559 566
    • (1990) Histochemistry , vol.93 , Issue.6 , pp. 559-566
    • Kristensen, P.1    Pyke, C.2    Lund, L.R.3    Andreasen, P.A.4    Dano, K.5
  • 81
    • 0026377425 scopus 로고
    • The plasminogen activation system in human colon cancer: Messenger RNA for the inhibitor PAI-1 is located in endothelial cells in the tumor stroma
    • Pyke C., Kristensen P., Ralfkiaer E., Eriksen J., Dano K. The plasminogen activation system in human colon cancer: messenger RNA for the inhibitor PAI-1 is located in endothelial cells in the tumor stroma. Cancer Res: 1991; 51 15 4067 4071
    • (1991) Cancer Res , vol.51 , Issue.15 , pp. 4067-4071
    • Pyke, C.1    Kristensen, P.2    Ralfkiaer, E.3    Eriksen, J.4    Dano, K.5
  • 82
    • 0028070859 scopus 로고
    • Prognostic impact of urokinase, urokinase receptor, and type 1 plasminogen activator inhibitor in squamous and large cell lung cancer tissue
    • Pedersen H., Brünner N., Francis D., et al. Prognostic impact of urokinase, urokinase receptor, and type 1 plasminogen activator inhibitor in squamous and large cell lung cancer tissue. Cancer Res: 1994; 54 17 4671 4675
    • (1994) Cancer Res , vol.54 , Issue.17 , pp. 4671-4675
    • Pedersen, H.1    Brünner, N.2    Francis, D.3
  • 83
    • 0028321634 scopus 로고
    • Prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in completely resected gastric cancer
    • Nekarda H., Schmitt M., Ulm K., et al. Prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in completely resected gastric cancer. Cancer Res: 1994; 54 11 2900 2907
    • (1994) Cancer Res , vol.54 , Issue.11 , pp. 2900-2907
    • Nekarda, H.1    Schmitt, M.2    Ulm, K.3
  • 84
    • 0033055316 scopus 로고    scopus 로고
    • Prognostic significance of urokinase (uPA) and its inhibitor PAI-1 for survival in advanced ovarian carcinoma stage FIGO IIIc
    • Kuhn W., Schmalfeldt B., Reuning U., et al. Prognostic significance of urokinase (uPA) and its inhibitor PAI-1 for survival in advanced ovarian carcinoma stage FIGO IIIc. Br J Cancer: 1999; 79 11-12 1746 1751
    • (1999) Br J Cancer , vol.79 , Issue.1112 , pp. 1746-1751
    • Kuhn, W.1    Schmalfeldt, B.2    Reuning, U.3
  • 85
    • 0028639208 scopus 로고
    • Impact of urokinase-type plasminogen activator and its inhibitor type 1 on prognosis in cervical cancer of the uterus
    • Kobayashi H., Fujishiro S., Terao T. Impact of urokinase-type plasminogen activator and its inhibitor type 1 on prognosis in cervical cancer of the uterus. Cancer Res: 1994; 54 24 6539 6548
    • (1994) Cancer Res , vol.54 , Issue.24 , pp. 6539-6548
    • Kobayashi, H.1    Fujishiro, S.2    Terao, T.3
  • 87
    • 0031902286 scopus 로고    scopus 로고
    • Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization
    • Bajou K., Noël A., Gerard R. D., et al. Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization. Nat Med: 1998; 4 8 923 928
    • (1998) Nat Med , vol.4 , Issue.8 , pp. 923-928
    • Bajou, K.1    Noël, A.2    Gerard, R.D.3
  • 88
    • 0035911151 scopus 로고    scopus 로고
    • The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies
    • Bajou K., Masson V., Gerard R. D., et al. The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies. J Cell Biol: 2001; 152 4 777 784
    • (2001) J Cell Biol , vol.152 , Issue.4 , pp. 777-784
    • Bajou, K.1    Masson, V.2    Gerard, R.D.3
  • 89
    • 4444376006 scopus 로고    scopus 로고
    • Association of psychosocial risk factors with risk of acute myocardial infarction in 11119 cases and 13648 controls from 52 countries (the INTERHEART study): Case-control study
    • INTERHEART investigators.
    • Rosengren A., Hawken S., Ôunpuu S., et al. INTERHEART investigators. Association of psychosocial risk factors with risk of acute myocardial infarction in 11119 cases and 13648 controls from 52 countries (the INTERHEART study): case-control study. Lancet: 2004; 364 9438 953 962
    • (2004) Lancet , vol.364 , Issue.9438 , pp. 953-962
    • Rosengren, A.1    Hawken, S.2    Ôunpuu, S.3
  • 91
    • 0032952042 scopus 로고    scopus 로고
    • Sympathetic nervous system activity and alpha-adrenergic responsiveness in older hypertensive humans
    • Supiano M. A., Hogikyan R. V., Sidani M. A., Galecki A. T., Krueger J. L. Sympathetic nervous system activity and alpha-adrenergic responsiveness in older hypertensive humans. Am J Physiol: 1999; 276 3 Pt 1 E519 E528
    • (1999) Am J Physiol , vol.276 , Issue.3 , pp. E519-E528
    • Supiano, M.A.1    Hogikyan, R.V.2    Sidani, M.A.3    Galecki, A.T.4    Krueger, J.L.5
  • 92
    • 0025287869 scopus 로고
    • Influence of metoprolol treatment on sympatho-adrenal activation of fibrinolysis
    • Larsson P. T., Wiman B., Olsson G., Angelin B., Hjemdahl P. Influence of metoprolol treatment on sympatho-adrenal activation of fibrinolysis. Thromb Haemost: 1990; 63 3 482 487
    • (1990) Thromb Haemost , vol.63 , Issue.3 , pp. 482-487
    • Larsson, P.T.1    Wiman, B.2    Olsson, G.3    Angelin, B.4    Hjemdahl, P.5
  • 93
    • 2942530422 scopus 로고    scopus 로고
    • Oxidative stress activates the plasminogen activator inhibitor type 1 (PAI-1) promoter through an AP-1 response element and cooperates with insulin for additive effects on PAI-1 transcription
    • Vulin A. I., Stanley F. M. Oxidative stress activates the plasminogen activator inhibitor type 1 (PAI-1) promoter through an AP-1 response element and cooperates with insulin for additive effects on PAI-1 transcription. J Biol Chem: 2004; 279 24 25172 25178
    • (2004) J Biol Chem , vol.279 , Issue.24 , pp. 25172-25178
    • Vulin, A.I.1    Stanley, F.M.2
  • 94
    • 0026740560 scopus 로고
    • Plasminogen activator inhibitor-1 messenger RNA expression is induced in rat hepatocytes in vivo by dexamethasone
    • Konkle B. A., Schuster S. J., Kelly M. D., et al. Plasminogen activator inhibitor-1 messenger RNA expression is induced in rat hepatocytes in vivo by dexamethasone. Blood: 1992; 79 10 2636 2642
    • (1992) Blood , vol.79 , Issue.10 , pp. 2636-2642
    • Konkle, B.A.1    Schuster, S.J.2    Kelly, M.D.3
  • 95
    • 0036891866 scopus 로고    scopus 로고
    • Aging and obesity augment the stress-induced expression of tissue factor gene in the mouse
    • Yamamoto K., Shimokawa T., Yi H., et al. Aging and obesity augment the stress-induced expression of tissue factor gene in the mouse. Blood: 2002; 100 12 4011 4018
    • (2002) Blood , vol.100 , Issue.12 , pp. 4011-4018
    • Yamamoto, K.1    Shimokawa, T.2    Yi, H.3
  • 96
    • 12244263052 scopus 로고    scopus 로고
    • Increased expression of plasminogen activator inhibitor-1 with fibrin deposition in a murine model of aging, Klotho mouse
    • Takeshita K., Yamamoto K., Ito M., et al. Increased expression of plasminogen activator inhibitor-1 with fibrin deposition in a murine model of aging, Klotho mouse. Semin Thromb Hemost: 2002; 28 6 545 554
    • (2002) Semin Thromb Hemost , vol.28 , Issue.6 , pp. 545-554
    • Takeshita, K.1    Yamamoto, K.2    Ito, M.3
  • 97
    • 0028088709 scopus 로고
    • Overexpression of plasminogen activator inhibitor type-1 in senescent fibroblasts from normal subjects and those with Werner syndrome
    • Goldstein S., Moerman E. J., Fujii S., Sobel B. E. Overexpression of plasminogen activator inhibitor type-1 in senescent fibroblasts from normal subjects and those with Werner syndrome. J Cell Physiol: 1994; 161 3 571 579
    • (1994) J Cell Physiol , vol.161 , Issue.3 , pp. 571-579
    • Goldstein, S.1    Moerman, E.J.2    Fujii, S.3    Sobel, B.E.4
  • 98
    • 0029559374 scopus 로고
    • Differential growth state-dependent regulation of plasminogen activator inhibitor type-1 expression in senescent IMR-90 human diploid fibroblasts
    • Mu X. C., Higgins P. J. Differential growth state-dependent regulation of plasminogen activator inhibitor type-1 expression in senescent IMR-90 human diploid fibroblasts. J Cell Physiol: 1995; 165 3 647 657
    • (1995) J Cell Physiol , vol.165 , Issue.3 , pp. 647-657
    • Mu, X.C.1    Higgins, P.J.2
  • 99
    • 0029144441 scopus 로고
    • Differential regulation of plasminogen activator and inhibitor gene transcription by the tumor suppressor p53
    • Kunz C., Pebler S., Otte J., von der Ahe D. Differential regulation of plasminogen activator and inhibitor gene transcription by the tumor suppressor p53. Nucleic Acids Res: 1995; 23 18 3710 3717
    • (1995) Nucleic Acids Res , vol.23 , Issue.18 , pp. 3710-3717
    • Kunz, C.1    Pebler, S.2    Otte, J.3    Von Der Ahe, D.4
  • 100
    • 33746616991 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence
    • Kortlever R. M., Higgins P. J., Bernards R. Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence. Nat Cell Biol: 2006; 8 8 877 884
    • (2006) Nat Cell Biol , vol.8 , Issue.8 , pp. 877-884
    • Kortlever, R.M.1    Higgins, P.J.2    Bernards, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.