메뉴 건너뛰기




Volumn 97, Issue 11, 1996, Pages 2440-2451

Fibrin deposition in tissues from endotoxin-treated mice correlates with decreases in the expression of urokinase-type but not tissue-type plasminogen activator

Author keywords

endotoxemia; gene expression; plasminogen activator inhibitor 1; thrombosis; tissue factor

Indexed keywords

AMINOCAPROIC ACID; ANTIFIBRINOLYTIC AGENT; ENDOTOXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; FIBRIN; MESSENGER RNA; OLIGONUCLEOTIDE; PLASMINOGEN ACTIVATOR INHIBITOR 1; THROMBOPLASTIN; TISSUE PLASMINOGEN ACTIVATOR; UROKINASE;

EID: 0029888356     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118691     Document Type: Article
Times cited : (187)

References (59)
  • 1
    • 0023898074 scopus 로고
    • Biology of disease: Acute inflammation and microthrombosis induced by endotoxin, interleukin-1, and tumor necrosis factor and their implication in gram-negative infection
    • Cybulsky, M.I., M.K.W. Chan, and H.Z. Movat. 1988. Biology of disease: acute inflammation and microthrombosis induced by endotoxin, interleukin-1, and tumor necrosis factor and their implication in gram-negative infection. Lab. Invest. 58:365-378.
    • (1988) Lab. Invest. , vol.58 , pp. 365-378
    • Cybulsky, M.I.1    Chan, M.K.W.2    Movat, H.Z.3
  • 2
    • 8944241418 scopus 로고
    • Disseminated intravascular coagulation and the kidney
    • Butterworth & Co., London
    • Kincaid-Smith, P., and J.A. Whitworth. 1989. Disseminated intravascular coagulation and the kidney. In Hemostasis and the Kidney. Butterworth & Co., London. 191-198.
    • (1989) Hemostasis and the Kidney , pp. 191-198
    • Kincaid-Smith, P.1    Whitworth, J.A.2
  • 3
    • 0001914635 scopus 로고
    • Pathology of sepsis, septic shock, and multiple organ failure
    • Society of Critical Care Medicine, Fullerton, CA
    • Coalson, J.J. 1986. Pathology of sepsis, septic shock, and multiple organ failure. In Perspective on Sepsis and Septic Shock. Society of Critical Care Medicine, Fullerton, CA. 27-59.
    • (1986) Perspective on Sepsis and Septic Shock , pp. 27-59
    • Coalson, J.J.1
  • 4
    • 0023079312 scopus 로고
    • Endotoxins and disease mechanisms
    • Morrison, D.C., and J.L. Ryan. 1987. Endotoxins and disease mechanisms. Annu. Rev. Med. 38:417-432.
    • (1987) Annu. Rev. Med. , vol.38 , pp. 417-432
    • Morrison, D.C.1    Ryan, J.L.2
  • 5
    • 0023089665 scopus 로고
    • Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro
    • Moore, K.L., S.P. Andreoli, N.L. Esmon, C.T. Esmon, and N.U. Bang. 1987. Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro. J. Clin. Invest. 79:124-130.
    • (1987) J. Clin. Invest. , vol.79 , pp. 124-130
    • Moore, K.L.1    Andreoli, S.P.2    Esmon, N.L.3    Esmon, C.T.4    Bang, N.U.5
  • 6
    • 0025875990 scopus 로고
    • The structural biology of expression and function of tissue factor
    • Edgington, T.S., N. Mackman, K. Brand, and W. Ruf. 1991. The structural biology of expression and function of tissue factor. Thromb. Haemostasis. 66:67-79.
    • (1991) Thromb. Haemostasis. , vol.66 , pp. 67-79
    • Edgington, T.S.1    Mackman, N.2    Brand, K.3    Ruf, W.4
  • 7
    • 0019957155 scopus 로고
    • Binding of human Factor VII and VIIa to monocytes
    • Broze, G.J., Jr. 1982. Binding of human Factor VII and VIIa to monocytes. J. Clin. Invest. 70:526-535.
    • (1982) J. Clin. Invest. , vol.70 , pp. 526-535
    • Broze Jr., G.J.1
  • 8
    • 0024308270 scopus 로고
    • Regulation of tissue factor gene expression in the monocyte procoagulant response to endotoxin
    • Gregory, S.A., J.H. Morrissey, and T.S. Edgington. 1989. Regulation of tissue factor gene expression in the monocyte procoagulant response to endotoxin. Mol. Cell. Biol. 9:2752-2755.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 2752-2755
    • Gregory, S.A.1    Morrissey, J.H.2    Edgington, T.S.3
  • 9
    • 0025344847 scopus 로고
    • The regulation of tissue factor mRNA in human endothelial cells in response to endotoxin or phorbol ester
    • Crossman, D.C., D.P. Carr, E.G.D. Tuddenham, J.D. Pearson, and J.H. McVey. 1990. The regulation of tissue factor mRNA in human endothelial cells in response to endotoxin or phorbol ester. J. Biol. Chem. 265:9782-9787.
    • (1990) J. Biol. Chem. , vol.265 , pp. 9782-9787
    • Crossman, D.C.1    Carr, D.P.2    Tuddenham, E.G.D.3    Pearson, J.D.4    McVey, J.H.5
  • 10
    • 0020658537 scopus 로고
    • Increased tissue thromboplastin activity in monocytes of patients with meningococcal infection related to an unfavorable prognosis
    • Osterud, B., and T. Flaegstad. 1983. Increased tissue thromboplastin activity in monocytes of patients with meningococcal infection related to an unfavorable prognosis. Thromb. Haemostasis. 49:5-7.
    • (1983) Thromb. Haemostasis. , vol.49 , pp. 5-7
    • Osterud, B.1    Flaegstad, T.2
  • 11
    • 0025213938 scopus 로고
    • Disseminated intravascular coagulation in rabbits induced by administration of endotoxin or tissue factor: Effect of anti-tissue factor antibodies and measurement of plasma extrinsic pathway inhibitor activity
    • Warr, T.A., L.V.M. Rao, and S.I. Rapaport. 1990. Disseminated intravascular coagulation in rabbits induced by administration of endotoxin or tissue factor: effect of anti-tissue factor antibodies and measurement of plasma extrinsic pathway inhibitor activity. Blood. 75:1481-1489.
    • (1990) Blood , vol.75 , pp. 1481-1489
    • Warr, T.A.1    Rao, L.V.M.2    Rapaport, S.I.3
  • 12
    • 0027725139 scopus 로고
    • Expression of tissue factor, thrombomodulin, and E-selectin in baboons with lethal Escherichia coli sepsis
    • Drake, T.A., J. Cheng, A. Chang, and F.B. Taylor. Jr. 1993. Expression of tissue factor, thrombomodulin, and E-selectin in baboons with lethal Escherichia coli sepsis. Am. J. Pathol. 142:1458-1470.
    • (1993) Am. J. Pathol. , vol.142 , pp. 1458-1470
    • Drake, T.A.1    Cheng, J.2    Chang, A.3    Taylor Jr., F.B.4
  • 13
    • 0027732172 scopus 로고
    • Murine tissue factor gene expression in vivo: Tissue and cell specificity and regulation by lipopolysaccharide
    • Mackman, N., M.S. Sawdey, M.R. Keeton, and D.J. Loskutoff. 1993. Murine tissue factor gene expression in vivo: tissue and cell specificity and regulation by lipopolysaccharide. Am. J. Pathol. 143:76-84.
    • (1993) Am. J. Pathol. , vol.143 , pp. 76-84
    • Mackman, N.1    Sawdey, M.S.2    Keeton, M.R.3    Loskutoff, D.J.4
  • 14
    • 0026053146 scopus 로고
    • The plasminogen activator/plasmin system
    • Vassalli, J.D., A. Sappino, and D. Belin. 1991. The plasminogen activator/plasmin system. J. Clin. Invest. 88:1067-1072.
    • (1991) J. Clin. Invest. , vol.88 , pp. 1067-1072
    • Vassalli, J.D.1    Sappino, A.2    Belin, D.3
  • 17
    • 0020472522 scopus 로고
    • Kinetics of the activation of plasminogen by human tissue plasminogen activator: Role of fibrin
    • Hoylaerts, M., D.C. Rijken, H.R. Lijnen, and D. Collen. 1982. Kinetics of the activation of plasminogen by human tissue plasminogen activator: role of fibrin. J. Biol. Chem. 257:2912-2919.
    • (1982) J. Biol. Chem. , vol.257 , pp. 2912-2919
    • Hoylaerts, M.1    Rijken, D.C.2    Lijnen, H.R.3    Collen, D.4
  • 18
    • 0026331304 scopus 로고
    • Basic and clinical aspects of fibrinolysis and thrombolysis
    • Collen, D., and H.R. Lijnen. 1991. Basic and clinical aspects of fibrinolysis and thrombolysis. Blood. 78:3114-3124.
    • (1991) Blood , vol.78 , pp. 3114-3124
    • Collen, D.1    Lijnen, H.R.2
  • 19
    • 0021261963 scopus 로고
    • Concomitant secretion of prourokinase and of a plasminogen activator-specific by cultured human monocytes-macrophages
    • Vassalli, J.-D., J.-M. Dayer, A. Wohlwend, and D. Belin. 1984. Concomitant secretion of prourokinase and of a plasminogen activator-specific by cultured human monocytes-macrophages. J. Exp. Med. 159:1653-1668.
    • (1984) J. Exp. Med. , vol.159 , pp. 1653-1668
    • Vassalli, J.-D.1    Dayer, J.-M.2    Wohlwend, A.3    Belin, D.4
  • 21
    • 0023197175 scopus 로고
    • Urokinase-type plasminogen activator. Proenzyme, receptor, and inhibitors
    • Blasi, F., J. Vassalli, and K. Dano. 1987. Urokinase-type plasminogen activator. Proenzyme, receptor, and inhibitors. J. Cell Biol. 104:801-804.
    • (1987) J. Cell Biol. , vol.104 , pp. 801-804
    • Blasi, F.1    Vassalli, J.2    Dano, K.3
  • 22
    • 0024568021 scopus 로고
    • Type 1 plasminogen activator inhibitor
    • B. Coller, editor. W.B. Saunders Co., Philadelphia
    • Loskutoff, D.J., M. Sawdey, and J. Mimuro. 1988. Type 1 plasminogen activator inhibitor. In Progress in Hemostasis and Thrombosis. B. Coller, editor. W.B. Saunders Co., Philadelphia. 87-115.
    • (1988) Progress in Hemostasis and Thrombosis , pp. 87-115
    • Loskutoff, D.J.1    Sawdey, M.2    Mimuro, J.3
  • 23
    • 0022354051 scopus 로고
    • Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction
    • Hamsten, A., B. Wiman, U. deFaire, and M. Blomback. 1985. Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction. N. Engl. J. Med. 313:1557-1563.
    • (1985) N. Engl. J. Med. , vol.313 , pp. 1557-1563
    • Hamsten, A.1    Wiman, B.2    DeFaire, U.3    Blomback, M.4
  • 24
    • 0024329641 scopus 로고
    • Incidence of increased plasminogen activator inhibitor in patients with deep venous thrombosis and/or pulmonary embolism
    • Tabernero, M.D., A. Estélles, V. Vicente, I. Alberca, and J. Aznar. 1989. Incidence of increased plasminogen activator inhibitor in patients with deep venous thrombosis and/or pulmonary embolism. Thromb. Res. 56:565-570.
    • (1989) Thromb. Res. , vol.56 , pp. 565-570
    • Tabernero, M.D.1    Estélles, A.2    Vicente, V.3    Alberca, I.4    Aznar, J.5
  • 26
    • 0025949379 scopus 로고
    • Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-α, and transforming growth factor-β
    • Sawdey, M.S., and D.J. Loskutoff. 1991. Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-α, and transforming growth factor-β. J. Clin. Invest. 88:1346-1353.
    • (1991) J. Clin. Invest. , vol.88 , pp. 1346-1353
    • Sawdey, M.S.1    Loskutoff, D.J.2
  • 27
    • 4243071616 scopus 로고
    • Kinetics of induction of PAI-1 gene expression on liver endothelial cells and hepatocytes by lipopolysaccharide (LPS)
    • Abstr.
    • Fearns, C., T. Thinnes, K. Roegner, and D.J. Loskutoff. 1993. Kinetics of induction of PAI-1 gene expression on liver endothelial cells and hepatocytes by lipopolysaccharide (LPS). Thromb. Haemostasis. 69:757a. (Abstr.)
    • (1993) Thromb. Haemostasis. , vol.69
    • Fearns, C.1    Thinnes, T.2    Roegner, K.3    Loskutoff, D.J.4
  • 28
    • 0014767655 scopus 로고
    • The importance of intravascular coagulation and inhibition of the fibrinolytic system in experimental fat embolism
    • Saldeen, T. 1970. The importance of intravascular coagulation and inhibition of the fibrinolytic system in experimental fat embolism. J. Trauma. 10: 287-298.
    • (1970) J. Trauma. , vol.10 , pp. 287-298
    • Saldeen, T.1
  • 29
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 30
    • 0023853291 scopus 로고
    • Molecular cloning of complementary DNA to mouse tissue plasminogen activator mRNA and its expression during F9 teratocarcinoma cell differentiation
    • Rickles, R.J., A.L. Darrow, and S. Strickland. 1988. Molecular cloning of complementary DNA to mouse tissue plasminogen activator mRNA and its expression during F9 teratocarcinoma cell differentiation. J. Biol. Chem. 263: 1563-1569.
    • (1988) J. Biol. Chem. , vol.263 , pp. 1563-1569
    • Rickles, R.J.1    Darrow, A.L.2    Strickland, S.3
  • 32
    • 0025122368 scopus 로고
    • The c-myc-regulated gene mrl encodes plasminogen activator inhibitor 1
    • Prendergast, G.C., L.E. Diamond, D. Dahl, and M.D. Cole. 1990. The c-myc-regulated gene mrl encodes plasminogen activator inhibitor 1. Mol. Cell. Biol. 10:1265-1269.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 1265-1269
    • Prendergast, G.C.1    Diamond, L.E.2    Dahl, D.3    Cole, M.D.4
  • 33
    • 0026572480 scopus 로고
    • Structure of the murine tissue factor gene. Chromosome location and conversation of regulatory elements in the promoter
    • Mackman, N., S. Imes, W.H. Maske, B. Taylor, A.J. Lusis, and T.A. Drake. 1992. Structure of the murine tissue factor gene. Chromosome location and conversation of regulatory elements in the promoter. Arterioscler. Thromb. 12:474-483.
    • (1992) Arterioscler. Thromb. , vol.12 , pp. 474-483
    • Mackman, N.1    Imes, S.2    Maske, W.H.3    Taylor, B.4    Lusis, A.J.5    Drake, T.A.6
  • 37
    • 0023056546 scopus 로고
    • Nucleotide sequence of a full-length cDNA for mouse cyloskeletal β-actin mRNA
    • Tokunaga, K., H. Taniguchi, K. Yoda, M. Shimizu, and S. Sakiyama. 1986. Nucleotide sequence of a full-length cDNA for mouse cyloskeletal β-actin mRNA. Nucleic Acids Res. 14:2829.
    • (1986) Nucleic Acids Res. , vol.14 , pp. 2829
    • Tokunaga, K.1    Taniguchi, H.2    Yoda, K.3    Shimizu, M.4    Sakiyama, S.5
  • 38
    • 0026642373 scopus 로고
    • Measurement of gastrin and transforming growth factor a messenger RNA levels in colonic carcinoma cell lines by quantitative polymerase chain reaction
    • Baldwin, G.S., and Q.-X. Zhang. 1992. Measurement of gastrin and transforming growth factor a messenger RNA levels in colonic carcinoma cell lines by quantitative polymerase chain reaction. Cancer Res. 52:2261-2267.
    • (1992) Cancer Res. , vol.52 , pp. 2261-2267
    • Baldwin, G.S.1    Zhang, Q.-X.2
  • 39
    • 0024828121 scopus 로고
    • Quantitation of mRNA by the polymerase chain reaction
    • Wang, A.M., M.V. Doyle, and D.F. Mark. 1989. Quantitation of mRNA by the polymerase chain reaction. Proc. Natl. Acad. Sci. USA. 86:9717-9721.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 9717-9721
    • Wang, A.M.1    Doyle, M.V.2    Mark, D.F.3
  • 40
    • 0030050952 scopus 로고    scopus 로고
    • Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor-α and lipopolysaccharide
    • Samad, F., K. Yamamoto, and D.J. Loskutoff. 1996. Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor-α and lipopolysaccharide. J. Clin. Invest. 97: 37-46.
    • (1996) J. Clin. Invest. , vol.97 , pp. 37-46
    • Samad, F.1    Yamamoto, K.2    Loskutoff, D.J.3
  • 41
    • 0027523918 scopus 로고
    • Cellular localization of type 1 plasminogen activator inhibitor mRNA and protein in murine renal tissue
    • Keeton, M., Y. Eguchi, M. Sawdey, C. Ahn, and D.J. Loskutoff. 1993. Cellular localization of type 1 plasminogen activator inhibitor mRNA and protein in murine renal tissue. Am. J. Pathol. 142:59-70.
    • (1993) Am. J. Pathol. , vol.142 , pp. 59-70
    • Keeton, M.1    Eguchi, Y.2    Sawdey, M.3    Ahn, C.4    Loskutoff, D.J.5
  • 42
    • 0024562002 scopus 로고
    • Promotion and subsequent inhibition of plasminogen activation after administration of intravenous endotoxin to normal subjects
    • Suffredini, A.F., P.C Harpel, and J.E. Parrillo. 1989. Promotion and subsequent inhibition of plasminogen activation after administration of intravenous endotoxin to normal subjects. N. Engl. J. Med. 320:1165-1172.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 1165-1172
    • Suffredini, A.F.1    Harpel, P.C.2    Parrillo, J.E.3
  • 43
    • 0025647250 scopus 로고
    • Experimental endotoxemia in humans: Analysis of cytokine release and coagulation, fibrinolytic, and complement pathways
    • van Deventer, S.J.H., H.R. Buller, J.W. ten Cate, L.A. Aarden, C.E. Hack, and A. Sturk. 1990. Experimental endotoxemia in humans: analysis of cytokine release and coagulation, fibrinolytic, and complement pathways. Blood. 76:2520-2526.
    • (1990) Blood , vol.76 , pp. 2520-2526
    • Van Deventer, S.J.H.1    Buller, H.R.2    Ten Cate, J.W.3    Aarden, L.A.4    Hack, C.E.5    Sturk, A.6
  • 44
    • 0002591417 scopus 로고
    • The absorption, distribution and excretion of epsilon-aminocaproic acid following oral or intravenous administration to man
    • McNicol, G.P., A.P. Fletcher, N. Alkjaersig. and S. Sherry. 1962. The absorption, distribution and excretion of epsilon-aminocaproic acid following oral or intravenous administration to man. J. Lab. Clin. Med. 59:15-21.
    • (1962) J. Lab. Clin. Med. , vol.59 , pp. 15-21
    • McNicol, G.P.1    Fletcher, A.P.2    Alkjaersig, N.3    Sherry, S.4
  • 45
    • 0025232878 scopus 로고
    • In vivo cytokine gene expression in T cell subsets of the autoimmune MRL/Mp-lpr/lpr mouse
    • Murray, L.J., R. Lee, and C. Martens. 1990. In vivo cytokine gene expression in T cell subsets of the autoimmune MRL/Mp-lpr/lpr mouse. Eur. J. Immunol. 20:163-170.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 163-170
    • Murray, L.J.1    Lee, R.2    Martens, C.3
  • 47
    • 0023866970 scopus 로고
    • Tissue plasminogen activator mRNA in murine tissues
    • Rickles, R.J., and S. Strickland. 1988. Tissue plasminogen activator mRNA in murine tissues. FEBS Lett. 229:100-106.
    • (1988) FEBS Lett. , vol.229 , pp. 100-106
    • Rickles, R.J.1    Strickland, S.2
  • 48
    • 0029082279 scopus 로고
    • Endotoxin stimulates murine urokinase-type plasminogen activator receptor gene expression in vivo
    • Almus-Jacobs, F., N. Varki, M.S. Sawdey, and D.J. Loskutoff. 1995. Endotoxin stimulates murine urokinase-type plasminogen activator receptor gene expression in vivo. Am. J. Pathol. 147:688-698.
    • (1995) Am. J. Pathol. , vol.147 , pp. 688-698
    • Almus-Jacobs, F.1    Varki, N.2    Sawdey, M.S.3    Loskutoff, D.J.4
  • 49
    • 0018834461 scopus 로고
    • Gram-negative bacteremia. IV. Re-evaluation of clinical features and treatment in 612 patients
    • Kreger, B., D. Craven, and W. McCabe. 1980. Gram-negative bacteremia. IV. Re-evaluation of clinical features and treatment in 612 patients. Am. J. Med. 68:344-355.
    • (1980) Am. J. Med. , vol.68 , pp. 344-355
    • Kreger, B.1    Craven, D.2    McCabe, W.3
  • 51
  • 52
    • 0014117474 scopus 로고
    • Intravascular coagulation in fluminant meningococcemia
    • McGehee, W.G., S.I. Rapaport, and P.F. Hjort. 1967. Intravascular coagulation in fluminant meningococcemia. Ann. Intern. Med. 67:250-260.
    • (1967) Ann. Intern. Med. , vol.67 , pp. 250-260
    • McGehee, W.G.1    Rapaport, S.I.2    Hjort, P.F.3
  • 53
    • 0020589345 scopus 로고
    • Distribution patterns of microthrombi in disseminated intravascular coagulation
    • Shimamura, K., K. Oka, M. Natazawa, and M. Kojima. 1983. Distribution patterns of microthrombi in disseminated intravascular coagulation. Arch. Pathol. Lab. Med. 107:543-547.
    • (1983) Arch. Pathol. Lab. Med. , vol.107 , pp. 543-547
    • Shimamura, K.1    Oka, K.2    Natazawa, M.3    Kojima, M.4
  • 54
    • 0018166873 scopus 로고
    • Immunoenzymehistochemical detection of fibrin microthrombi during disseminated intravascular coagulation in rats
    • Craane, H., J.J. Emeis, J. Lindeman, and W. Nieuwenhuizen. 1978. Immunoenzymehistochemical detection of fibrin microthrombi during disseminated intravascular coagulation in rats. Histochemistry. 57:97-105.
    • (1978) Histochemistry , vol.57 , pp. 97-105
    • Craane, H.1    Emeis, J.J.2    Lindeman, J.3    Nieuwenhuizen, W.4
  • 56
    • 0014677162 scopus 로고
    • Glomerular capillary thrombosis and acute renal failure after epsilon-amino caproic acid therapy
    • Charytan, C., and D. Purtilio. 1969. Glomerular capillary thrombosis and acute renal failure after epsilon-amino caproic acid therapy. N. Engl. J. Med. 280:1102-1104.
    • (1969) N. Engl. J. Med. , vol.280 , pp. 1102-1104
    • Charytan, C.1    Purtilio, D.2
  • 58
    • 0025821447 scopus 로고
    • Regulation of the tissue factor pathway
    • Rapaport, S.I. 1991. Regulation of the tissue factor pathway. Ann. NY Acad. Sci. 614:51-62.
    • (1991) Ann. NY Acad. Sci. , vol.614 , pp. 51-62
    • Rapaport, S.I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.