Oxidative stress protection by exogenous delivery of rhhsp70 chaperone to the retinal pigment epithelium (RPE), a possible therapeutic strategy against RPE degeneration

Pharmaceutical Research

Volumn 32, Issue 1, 2015, Pages 211-221

  Subrizi, Astrid ^a   Toropainen, Elisa ^b   Ramsay, Eva ^a   Airaksinen, Anu J ^a   Kaarniranta, Kai ^b,c   Urtti, Arto ^a,b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

AMD; Hsp70; Oxidative stress; Protein delivery; RPE

Indexed keywords

HEAT SHOCK PROTEIN 70; HYDROGEN PEROXIDE; INTERLEUKIN 6; RECOMBINANT PROTEIN;

ANIMAL; CELL LINE; CELL SURVIVAL; CULTURE TECHNIQUE; DRUG EFFECTS; HUMAN; IMMUNOLOGY; INTRAVITREAL DRUG ADMINISTRATION; MACULAR DEGENERATION; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; PIG; PIGMENT EPITHELIUM; SECRETION (PROCESS); TISSUE DISTRIBUTION;

ANIMALS; CELL CULTURE TECHNIQUES; CELL LINE; CELL SURVIVAL; HSP70 HEAT-SHOCK PROTEINS; HUMANS; HYDROGEN PEROXIDE; INTERLEUKIN-6; INTRAVITREAL INJECTIONS; MACULAR DEGENERATION; OXIDATIVE STRESS; RECOMBINANT PROTEINS; RETINAL PIGMENT EPITHELIUM; SWINE; TISSUE DISTRIBUTION;

EID: 84939878208     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-014-1456-6     Document Type: Article

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