Proteomic profiling of human retinal pigment epithelium exposed to an advanced glycation-modified substrate

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 250, Issue 3, 2012, Pages 349-359

  Glenn, J V ^a,d   Mahaffy, H ^a,d   Dasari, S ^a,d   Oliver, M ^b   Chen, M ^a,b   Boulton, M E ^c   Xu, H ^a,b   Curry, W J ^a   Stitt, Alan W ^a,b  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b Waters MS Technologies Centre   (United Kingdom)

^c UNIVERSITY OF FLORIDA   (United States)

^d QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Advanced glycation endproducts; Bruch's membrane; RPE; Ubiquitin carboxyterminal hydrolase 1

Indexed keywords

ADVANCED GLYCATION END PRODUCT; AMINOACYLASE; BINDING PROTEIN; C MYC PROMOTER BINDING PROTEIN; CALMODULIN; CALRETICULIN; CATHEPSIN D; CONTRACTILE PROTEIN; GALECTIN 1; GLUTATHIONE PEROXIDASE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN BETA 1; LYMPHOTOXIN; MYOSIN LIGHT CHAIN; MYOSIN LIGHT POLYPEPTIDE 6; NEURON SPECIFIC ENOLASE; NUCLEOPHOSMIN; PEROXIDE; PHOSPHATASE; PHOSPHOGLYCERATE KINASE; PHOSPHOHISTIDINE PHOSPHATASE; PROTEIN DISULFIDE ISOMERASE; PROTEOME; SUPEROXIDE DISMUTASE; THIOREDOXIN DEPENDENT PEROXIDE; TRIOSEPHOSPHATE ISOMERASE; UBIQUITIN THIOLESTERASE; UNCLASSIFIED DRUG; EYE PROTEIN; UCHL1 PROTEIN, HUMAN;

AGED; AGING; ARTICLE; BASEMENT MEMBRANE; CELL CULTURE; CONTROLLED STUDY; DENSITOMETRY; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOCYTOCHEMISTRY; MONOLAYER CULTURE; NUCLEOTIDE SEQUENCE; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEOMICS; TWO DIMENSIONAL GEL ELECTROPHORESIS; UPREGULATION; BRUCH MEMBRANE; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; METABOLISM; PROTEIN MICROARRAY; TANDEM MASS SPECTROMETRY;

BRUCH MEMBRANE; CELLS, CULTURED; DENSITOMETRY; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; EYE PROTEINS; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; IMMUNOHISTOCHEMISTRY; PROTEIN ARRAY ANALYSIS; PROTEOMICS; RETINAL PIGMENT EPITHELIUM; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; UBIQUITIN THIOLESTERASE; UP-REGULATION;

EID: 84861144268     PISSN: 0721832X     EISSN: 1435702X     Source Type: Journal    
DOI: 10.1007/s00417-011-1856-9     Document Type: Article

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