Celastrol regulates innate immunity response via NF-B and Hsp70 in human retinal pigment epithelial cells

Pharmacological Research

Volumn 64, Issue 5, 2011, Pages 501-508

  Paimela, Tuomas ^a   Hyttinen, Juha M T ^a   Viiri, Johanna ^a   Ryhänen, Tuomas ^a   Karjalainen, Reijo O ^a   Salminen, Antero ^a,b   Kaarniranta, Kai ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Celastrol; Hsp70; Innate immunity; Nf B; Retinal pigment epithelium

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CELASTROL; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; SERINE; SMALL INTERFERING RNA; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR RELA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENE SILENCING; HEAT SHOCK PROTEIN 70 GENE; HUMAN; HUMAN CELL; IMMUNE RESPONSE GENE; IMMUNOMODULATION; IMMUNOREGULATION; INNATE IMMUNITY; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

EID: 80055015419     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2011.05.027     Document Type: Article

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