4-acetoxyphenol prevents RPE oxidative stress–induced necrosis by functioning as an NRF2 stabilizer

Investigative Ophthalmology and Visual Science

Volumn 56, Issue 9, 2015, Pages 5048-5059

  Hanus, Jakub ^a   Kolkin, Alexander ^a   Chimienti, Julia ^a   Botsay, Sara ^b   Wang, Shusheng ^a,c  

^a Tulane University   (United States)

^b Southern Eye Bank ^*  (United States)

^c TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

4 Acetoxyphenol (4 AC); Age related macular degeneration; Geographic atrophy; Necrosis; NF E2 related factor 2 (NRF2)

Indexed keywords

REACTIVE OXYGEN METABOLITE; TERT BUTYL HYDROPEROXIDE; TRANSCRIPTION FACTOR NRF2;

APOPTOSIS; CELL LINE; CELL SURVIVAL; DRUG EFFECTS; HUMAN; METABOLISM; NECROSIS; OXIDATIVE STRESS; PATHOLOGY; PIGMENT EPITHELIUM; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; HUMANS; NECROSIS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RETINAL PIGMENT EPITHELIUM; TERT-BUTYLHYDROPEROXIDE;

EID: 84939808880     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.15-16401     Document Type: Article

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