Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells

Chemico-Biological Interactions

Volumn 240, Issue , 2015, Pages 12-21

  Lin, Chih Li ^a,b   Huang, Wen Nung ^a   Li, Hsin Hua ^a   Huang, Chien Ning ^a   Hsieh, Sam ^c   Lai, Copper ^d   Lu, Fung Jou ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c Unitira Applied Materials Corp   (Taiwan)

^d Fluxtek International Corp   (Taiwan)

Author keywords

AMP activated protein kinase; Amyloid ; Forkhead box protein O3a; Hydrogen rich water; Sirtuin 1

Indexed keywords

CASPASE 3; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; HYDROGEN PEROXIDE; HYDROGEN RICH WATER; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; NEUROPROTECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; SIRTUIN 1; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, MOUSE; HYDROGEN; SCAVENGER; WATER;

ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG MECHANISM; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL NECROSIS; NEUROBLASTOMA CELL LINE; OXIDATIVE STRESS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SK N MC CELL LINE; UPREGULATION; APOPTOSIS; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; NERVE CELL; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; AMYLOID BETA-PEPTIDES; APOPTOSIS; CELL LINE, TUMOR; FORKHEAD TRANSCRIPTION FACTORS; FREE RADICAL SCAVENGERS; HUMANS; HYDROGEN; NEURONS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIRTUIN 1; WATER;

EID: 84939783007     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.07.013     Document Type: Article

References (40)

1. B.J. Gilbert The role of amyloid beta in the pathogenesis of Alzheimer's disease J. Clin. Pathol. 66 2013 362 366
2. A.Y. Abramov, L. Canevari, and M.R. Duchen Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase J. Neurosci. Off. J. Soc. Neurosci. 24 2004 565 575
3. D. Paris, T.A. Parker, T. Town, Z. Suo, C. Fang, J. Humphrey, F. Crawford, and M. Mullan Role of peroxynitrite in the vasoactive and cytotoxic effects of Alzheimer's beta-amyloid1-40 peptide Exp. Neurol. 152 1998 116 122
4. G.L. Caldeira, I.L. Ferreira, and A.C. Rego Impaired transcription in Alzheimer's disease: key role in mitochondrial dysfunction and oxidative stress J. Alzheimer's Dis. JAD 34 2013 115 131
5. J.F. Turrens Mitochondrial formation of reactive oxygen species J. Physiol. 552 2003 335 344
6. P.L. de Keizer, B.M. Burgering, and T.B. Dansen Forkhead box o as a sensor, mediator, and regulator of redox signaling Antioxid. Redox Signal. 14 2011 1093 1106
7. Y.S. Hori, A. Kuno, R. Hosoda, and Y. Horio Regulation of FOXOs and p53 by SIRT1 modulators under oxidative stress PLoS One 8 2013 e73875
8. A. Salminen, K. Kaarniranta, and A. Kauppinen Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process Int. J. Mol. Sci. 14 2013 3834 3859
9. A. van der Horst, and B.M. Burgering Stressing the role of FoxO proteins in lifespan and disease, nature reviews Mol. Cell Biol. 8 2007 440 450
10. M. Monsalve, and Y. Olmos The complex biology of FOXO Curr. Drug Targets 12 2011 1322 1350
11. S. Ohta Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine Pharmacol. Ther. 144 2014 1 11
12. G. Song, M. Li, H. Sang, L. Zhang, X. Li, S. Yao, Y. Yu, C. Zong, Y. Xue, and S. Qin Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome J. Lipid Res. 54 2013 1884 1893
13. Y. Hong, A. Shao, J. Wang, S. Chen, H. Wu, D.W. McBride, Q. Wu, X. Sun, and J. Zhang Neuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt/GSK3beta signaling pathway PLoS One 9 2014 e96212
14. J. Shi, F. Yao, C. Zhong, X. Pan, Y. Yang, and Q. Lin Hydrogen saline is protective for acute lung ischaemia/reperfusion injuries in rats Heart, Lung Circ. 21 2012 556 563
15. J. Li, Y. Dong, H. Chen, H. Han, Y. Yu, G. Wang, Y. Zeng, and K. Xie Protective effects of hydrogen-rich saline in a rat model of permanent focal cerebral ischemia via reducing oxidative stress and inflammatory cytokines Brain Res. 1486 2012 103 111
16. K. Ohno, M. Ito, M. Ichihara, and M. Ito Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases Oxid. Med. Cell. Longev. 2012 2012 353152
17. C. Xia, W. Liu, D. Zeng, L. Zhu, X. Sun, and X. Sun Effect of hydrogen-rich water on oxidative stress, liver function, and viral load in patients with chronic hepatitis B Clin. Transl. Sci. 6 2013 372 375
18. S. Matsumoto, T. Ueda, and H. Kakizaki Effect of supplementation with hydrogen-rich water in patients with interstitial cystitis/painful bladder syndrome Urology 81 2013 226 230
19. T. Wang, L. Zhao, M. Liu, F. Xie, X. Ma, P. Zhao, Y. Liu, J. Li, M. Wang, Z. Yang, and Y. Zhang Oral intake of hydrogen-rich water ameliorated chlorpyrifos-induced neurotoxicity in rats Toxicol. Appl. Pharmacol. 280 2014 169 176
20. J. Li, C. Wang, J.H. Zhang, J.M. Cai, Y.P. Cao, and X.J. Sun Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress Brain Res. 1328 2010 152 161
21. J. Ren, Z. Luo, F. Tian, Q. Wang, K. Li, and C. Wang Hydrogen-rich saline reduces the oxidative stress and relieves the severity of trauma-induced acute pancreatitis in rats J. Trauma Acute Care Surg. 72 2012 1555 1561
22. K. Aoki, A. Nakao, T. Adachi, Y. Matsui, and S. Miyakawa Pilot study: effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes Med. Gas Res. 2 2012 12
23. K. Noda, Y. Tanaka, N. Shigemura, T. Kawamura, Y. Wang, K. Masutani, X. Sun, Y. Toyoda, C.A. Bermudez, and A. Nakao Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration Transpl. Int. Off. J. Eur. Soc. Organ Transplant. 25 2012 1213 1222
24. F.J. Lu, J.T. Lin, H.P. Wang, and W.C. Huang A simple, sensitive, non-stimulated photon counting system for detection of superoxide anion in whole blood Experientia 52 1996 141 144
25. J. Zielonka, and B. Kalyanaraman Hydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: another inconvenient truth Free Radic. Biol. Med. 48 2010 983 1001
26. V. Vingtdeux, L. Giliberto, H. Zhao, P. Chandakkar, Q. Wu, J.E. Simon, E.M. Janle, J. Lobo, M.G. Ferruzzi, P. Davies, and P. Marambaud AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism J. Biol. Chem. 285 2010 9100 9113
27. K. Hasegawa, S. Wakino, K. Yoshioka, S. Tatematsu, Y. Hara, H. Minakuchi, N. Washida, H. Tokuyama, K. Hayashi, and H. Itoh Sirt1 protects against oxidative stress-induced renal tubular cell apoptosis by the bidirectional regulation of catalase expression Biochem. Biophys. Res. Commun. 372 2008 51 56
28. S. Gandhi, and A.Y. Abramov Mechanism of oxidative stress in neurodegeneration Oxid. Med. Cell. Longev. 2012 2012 428010
29. C. Cencioni, F. Spallotta, F. Martelli, S. Valente, A. Mai, A.M. Zeiher, and C. Gaetano Oxidative stress and epigenetic regulation in ageing and age-related diseases Int. J. Mol. Sci. 14 2013 17643 17663
30. A. Salminen, and K. Kaarniranta AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network Ageing Res. Rev. 11 2012 230 241
31. H. Amitani, A. Asakawa, K. Cheng, M. Amitani, K. Kaimoto, M. Nakano, M. Ushikai, Y. Li, M. Tsai, J.B. Li, M. Terashi, H. Chaolu, R. Kamimura, and A. Inui Hydrogen improves glycemic control in type1 diabetic animal model by promoting glucose uptake into skeletal muscle PLoS One 8 2013 e53913
32. X. Zhou, Y. Cao, G. Ao, L. Hu, H. Liu, J. Wu, X. Wang, M. Jin, S. Zheng, X. Zhen, N.J. Alkayed, J. Jia, and J. Cheng CaMKKbeta-dependent activation of AMP-activated protein kinase is critical to suppressive effects of hydrogen sulfide on neuroinflammation Antioxid. Redox Signal. 21 2014 1741 1758
33. A. Brunet, L.B. Sweeney, J.F. Sturgill, K.F. Chua, P.L. Greer, Y. Lin, H. Tran, S.E. Ross, R. Mostoslavsky, H.Y. Cohen, L.S. Hu, H.L. Cheng, M.P. Jedrychowski, S.P. Gygi, D.A. Sinclair, F.W. Alt, and M.E. Greenberg Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase Science (New York, N.Y.) 303 2004 2011 2015
34. H. Yao, D. Zhao, S.H. Khan, and L. Yang Role of autophagy in prion protein-induced neurodegenerative diseases Acta Biochim. Biophys. Sinica 45 2013 494 502
35. F. Chiacchiera, and C. Simone The AMPK-FoxO3A axis as a target for cancer treatment Cell Cycle (Georgetown, Tex.) 9 2010 1091 1096
36. V. Kumar, and K.D. Gill Oxidative stress and mitochondrial dysfunction in aluminium neurotoxicity and its amelioration: a review Neurotoxicology 41C 2014 154 166
37. S. Mondragon-Rodriguez, G. Perry, X. Zhu, P.I. Moreira, M.C. Acevedo-Aquino, and S. Williams Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer's disease Oxid. Med. Cell. Longev. 2013 2013 940603
38. Y. Luo, X. Yang, S. Zhao, C. Wei, Y. Yin, T. Liu, S. Jiang, J. Xie, X. Wan, M. Mao, and J. Wu Hydrogen sulfide prevents OGD/R-induced apoptosis via improving mitochondrial dysfunction and suppressing an ROS-mediated caspase-3 pathway in cortical neurons Neurochem. Int. 63 2013 826 831
39. A.D. Kim, K.A. Kang, M.J. Piao, K.C. Kim, J. Zheng, C.W. Yao, J.W. Cha, C.L. Hyun, H.K. Kang, N.H. Lee, and J.W. Hyun Cytoprotective effect of eckol against oxidative stress-induced mitochondrial dysfunction: involvement of the FoxO3a/AMPK pathway J. Cell. Biochem. 115 2014 1403 1411
40. H.H. Li, F.J. Lu, H.C. Hung, G.Y. Liu, T.J. Lai, and C.L. Lin Humic acid increases amyloid beta-induced cytotoxicity by induction of ER stress in human SK-N-MC neuronal cells Int. J. Mol. Sci. 16 2015 10426 10442