Humic acid increases amyloid β-induced cytotoxicity by induction of ER stress in human SK-N-MC neuronal cells

International Journal of Molecular Sciences

Volumn 16, Issue 5, 2015, Pages 10426-10442

  Li, Hsin Hua ^a   Lu, Fung Jou ^a   Hung, Hui Chih ^b   Liu, Guang Yaw ^a   Lai, Te Jen ^a,c   Lin, Chih Li ^a,c  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Amyloid ; Endoplasmic reticulum stress; Humic acid; PPAR coactivator 1 ; Sirtuin 1

Indexed keywords

AMYLOID BETA PROTEIN; CASPASE 3; HUMIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; X BOX BINDING PROTEIN 1; CINNAMIC ACID DERIVATIVE; HUMIC SUBSTANCE; PERK KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PPARGC1A PROTEIN, HUMAN; PROTEIN KINASE R; SALUBRINAL; SIRT1 PROTEIN, HUMAN; SIRTUIN 1; THIOUREA; TRANSCRIPTION FACTOR;

ABSORPTION CHROMATOGRAPHY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENDOPLASMIC RETICULUM STRESS; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MTT ASSAY; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; DRUG EFFECTS; HUMIC SUBSTANCE; METABOLISM; NERVE CELL; TOXICITY; TUMOR CELL LINE;

AMYLOID BETA-PEPTIDES; CELL LINE, TUMOR; CINNAMATES; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; HUMANS; HUMIC SUBSTANCES; NEURONS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA; SIRTUIN 1; THIOUREA; TRANSCRIPTION FACTORS;

EID: 84929353023     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms160510426     Document Type: Article

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