-
1
-
-
84965822602
-
Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay
-
Alley MC, Scudiero DA, Monks A, Hursey ML, Czerwinski MJ, Fine DL, Abbott BJ, Mayo JG, Shoemaker RH, Boyd MR,. 1988. Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay. Cancer Res 48: 589-601.
-
(1988)
Cancer Res
, vol.48
, pp. 589-601
-
-
Alley, M.C.1
Scudiero, D.A.2
Monks, A.3
Hursey, M.L.4
Czerwinski, M.J.5
Fine, D.L.6
Abbott, B.J.7
Mayo, J.G.8
Shoemaker, R.H.9
Boyd, M.R.10
-
2
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
Balaban RS, Nemoto S, Finkel T,. 2005. Mitochondria, oxidants, and aging. Cell 120: 483-495.
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
3
-
-
0033083310
-
Elevation of mitochondrial transmembrane potential and reactive oxygen intermediate levels are early events and occur independently from activation of caspases in Fas signaling
-
Banki K, Hutter E, Gonchoroff NJ, Perl A,. 1999. Elevation of mitochondrial transmembrane potential and reactive oxygen intermediate levels are early events and occur independently from activation of caspases in Fas signaling. J Immunol 162: 1466-1479.
-
(1999)
J Immunol
, vol.162
, pp. 1466-1479
-
-
Banki, K.1
Hutter, E.2
Gonchoroff, N.J.3
Perl, A.4
-
4
-
-
0023130372
-
Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing
-
Carmichael J, DeGraff WG, Gazdar AF, Minna JD, Mitchell JB,. 1987. Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing. Cancer Res 47: 936-942.
-
(1987)
Cancer Res
, vol.47
, pp. 936-942
-
-
Carmichael, J.1
Degraff, W.G.2
Gazdar, A.F.3
Minna, J.D.4
Mitchell, J.B.5
-
5
-
-
84866998904
-
Mitochondria in traumatic brain injury and mitochondrial-targeted multipotential therapeutic strategies
-
Cheng G, Kong RH, Zhang LM, Zhang JN,. 2012. Mitochondria in traumatic brain injury and mitochondrial-targeted multipotential therapeutic strategies. Br J Pharmacol 167: 699-719.
-
(2012)
Br J Pharmacol
, vol.167
, pp. 699-719
-
-
Cheng, G.1
Kong, R.H.2
Zhang, L.M.3
Zhang, J.N.4
-
6
-
-
0037204586
-
Role of mitochondria in serum withdrawal-induced apoptosis of immortalized neuronal precursors
-
Colombaioni L, Colombini L, Garcia-Gil M,. 2002. Role of mitochondria in serum withdrawal-induced apoptosis of immortalized neuronal precursors. Brain Res Dev Brain Res 134: 93-102.
-
(2002)
Brain Res Dev Brain Res
, vol.134
, pp. 93-102
-
-
Colombaioni, L.1
Colombini, L.2
Garcia-Gil, M.3
-
7
-
-
0033042094
-
Novel effects of FCCP [carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone] on amyloid precursor protein processing
-
Connop BP, Thies RL, Beyreuther K, Ida N, Reiner PB,. 1999. Novel effects of FCCP [carbonyl cyanide p-(trifluoromethoxy)phenylhydrazone] on amyloid precursor protein processing. J Neurochem 72: 1457-1465.
-
(1999)
J Neurochem
, vol.72
, pp. 1457-1465
-
-
Connop, B.P.1
Thies, R.L.2
Beyreuther, K.3
Ida, N.4
Reiner, P.B.5
-
8
-
-
19444387198
-
Free radicals and antioxidants in human health: Current status and future prospects
-
Devasagayam TP, Tilak JC, Boloor KK, Sane KS, Ghaskadbi SS, Lele RD,. 2004. Free radicals and antioxidants in human health: Current status and future prospects. J Assoc Physicians India 52: 794-804.
-
(2004)
J Assoc Physicians India
, vol.52
, pp. 794-804
-
-
Devasagayam, T.P.1
Tilak, J.C.2
Boloor, K.K.3
Sane, K.S.4
Ghaskadbi, S.S.5
Lele, R.D.6
-
9
-
-
0029053451
-
Superoxide radical and superoxide dismutases
-
Fridovich I,. 1995. Superoxide radical and superoxide dismutases. Annu Rev Biochem 64: 97-112.
-
(1995)
Annu Rev Biochem
, vol.64
, pp. 97-112
-
-
Fridovich, I.1
-
10
-
-
0001255850
-
Eckols, novel phlorotannins with a dibenzo-p-dioxin skeleton possing inhibitory effects on α2-macroglobulin from the brown alga Ecklonia kurome Okamura
-
Fukuyama Y, Miura I, Kinzyo Z, Mori H, Kido M, Nakayama Y, Takahashi M, Ochi M,. 1985. Eckols, novel phlorotannins with a dibenzo-p-dioxin skeleton possing inhibitory effects on α2-macroglobulin from the brown alga Ecklonia kurome Okamura. Chem Lett 14: 739-742.
-
(1985)
Chem Lett
, vol.14
, pp. 739-742
-
-
Fukuyama, Y.1
Miura, I.2
Kinzyo, Z.3
Mori, H.4
Kido, M.5
Nakayama, Y.6
Takahashi, M.7
Ochi, M.8
-
11
-
-
0037975597
-
Cytokines and BCR-ABL mediate suppression of TRAIL-induced apoptosis through inhibition of forkhead FOXO3a transcription factor
-
Ghaffari S, Jagani Z, Kitidis C, Lodish HF, Khosravi-Far R,. 2003. Cytokines and BCR-ABL mediate suppression of TRAIL-induced apoptosis through inhibition of forkhead FOXO3a transcription factor. Proc Natl Acad Sci USA 100: 6523-6528.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 6523-6528
-
-
Ghaffari, S.1
Jagani, Z.2
Kitidis, C.3
Lodish, H.F.4
Khosravi-Far, R.5
-
12
-
-
34848861463
-
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor
-
Greer EL, Oskoui PR, Banko MR, Maniar JM, Gygi MP, Gygi SP, Brunet A,. 2007. The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J Biol Chem 282: 30107-30119.
-
(2007)
J Biol Chem
, vol.282
, pp. 30107-30119
-
-
Greer, E.L.1
Oskoui, P.R.2
Banko, M.R.3
Maniar, J.M.4
Gygi, M.P.5
Gygi, S.P.6
Brunet, A.7
-
13
-
-
77952741468
-
Metformin reduces intracellular reactive oxygen species levels by upregulating expression of the antioxidant thioredoxin via the AMPK-FOXO3 pathway
-
Hou X, Song J, Li XN, Zhang L, Wang X, Chen L, Shen YH,. 2010. Metformin reduces intracellular reactive oxygen species levels by upregulating expression of the antioxidant thioredoxin via the AMPK-FOXO3 pathway. Biochem Biophys Res Commun 396: 199-205.
-
(2010)
Biochem Biophys Res Commun
, vol.396
, pp. 199-205
-
-
Hou, X.1
Song, J.2
Li, X.N.3
Zhang, L.4
Wang, X.5
Chen, L.6
Shen, Y.H.7
-
14
-
-
79958004725
-
Eckol suppresses maintenance of stemness and malignancies in glioma stem-like cells
-
Hyun KH, Yoon CH, Kim RK, Lim EJ, An S, Park MJ, Hyun JW, Suh Y, Kim MJ, Lee SJ,. 2011. Eckol suppresses maintenance of stemness and malignancies in glioma stem-like cells. Toxicol Appl Pharmacol 254: 32-40.
-
(2011)
Toxicol Appl Pharmacol
, vol.254
, pp. 32-40
-
-
Hyun, K.H.1
Yoon, C.H.2
Kim, R.K.3
Lim, E.J.4
An, S.5
Park, M.J.6
Hyun, J.W.7
Suh, Y.8
Kim, M.J.9
Lee, S.J.10
-
15
-
-
27744511937
-
Eckol isolated from Ecklonia cava attenuates oxidative stress induced cell damage in lung fibroblast cells
-
Kang KA, Lee KH, Chae S, Zhang R, Jung MS, Lee Y, Kim SY, Kim HS, Joo HG, Park JW, Ham YM, Lee NH, Hyun JW,. 2005. Eckol isolated from Ecklonia cava attenuates oxidative stress induced cell damage in lung fibroblast cells. FEBS Lett 579: 6295-6304.
-
(2005)
FEBS Lett
, vol.579
, pp. 6295-6304
-
-
Kang, K.A.1
Lee, K.H.2
Chae, S.3
Zhang, R.4
Jung, M.S.5
Lee, Y.6
Kim, S.Y.7
Kim, H.S.8
Joo, H.G.9
Park, J.W.10
Ham, Y.M.11
Lee, N.H.12
Hyun, J.W.13
-
16
-
-
73749083990
-
Up-regulation of Nrf2-mediated heme oxygenase-1 expression by eckol, a phlorotannin compound, through activation of Erk and PI3K/Akt
-
Kim KC, Kang KA, Zhang R, Piao MJ, Kim GY, Kang MY, Lee SJ, Lee NH, Surh YJ, Hyun JW,. 2010. Up-regulation of Nrf2-mediated heme oxygenase-1 expression by eckol, a phlorotannin compound, through activation of Erk and PI3K/Akt. Int J Biochem Cell Biol 42: 297-305.
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 297-305
-
-
Kim, K.C.1
Kang, K.A.2
Zhang, R.3
Piao, M.J.4
Kim, G.Y.5
Kang, M.Y.6
Lee, S.J.7
Lee, N.H.8
Surh, Y.J.9
Hyun, J.W.10
-
17
-
-
0032863928
-
Overexpression of manganese superoxide dismutase protects against mitochondrial-initiated poly (ADP-ribose) polymerase-mediated cell death
-
Kiningham KK, Oberley TD, Lin S, Mattingly CA, St Clair DK,. 1999. Overexpression of manganese superoxide dismutase protects against mitochondrial-initiated poly (ADP-ribose) polymerase-mediated cell death. FASEB J 13: 1601-1610.
-
(1999)
FASEB J
, vol.13
, pp. 1601-1610
-
-
Kiningham, K.K.1
Oberley, T.D.2
Lin, S.3
Mattingly, C.A.4
St Clair, D.K.5
-
18
-
-
0035782650
-
Reactive oxygen species and mitochondrial diseases
-
Kirkinezos IG, Moraes CT,. 2001. Reactive oxygen species and mitochondrial diseases. Semin Cell Dev Biol 12: 449-457.
-
(2001)
Semin Cell Dev Biol
, vol.12
, pp. 449-457
-
-
Kirkinezos, I.G.1
Moraes, C.T.2
-
19
-
-
0037136563
-
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
-
Kops GJ, Dansen TB, Polderman PE, Saarloos I, Wirtz KW, Coffer PJ, Huang TT, Bos JL, Medema RH, Burgering BM,. 2002. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature 419: 316-321.
-
(2002)
Nature
, vol.419
, pp. 316-321
-
-
Kops, G.J.1
Dansen, T.B.2
Polderman, P.E.3
Saarloos, I.4
Wirtz, K.W.5
Coffer, P.J.6
Huang, T.T.7
Bos, J.L.8
Medema, R.H.9
Burgering, B.M.10
-
20
-
-
70349633673
-
Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin
-
Li XN, Song J, Zhang L, LeMaire SA, Hou X, Zhang C, Coselli JS, Chen L, Wang XL, Zhang Y, Shen YH,. 2009. Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin. Diabetes 58: 2246-2257.
-
(2009)
Diabetes
, vol.58
, pp. 2246-2257
-
-
Li, X.N.1
Song, J.2
Zhang, L.3
Lemaire, S.A.4
Hou, X.5
Zhang, C.6
Coselli, J.S.7
Chen, L.8
Wang, X.L.9
Zhang, Y.10
Shen, Y.H.11
-
21
-
-
33947512416
-
Mitochondrial dysfunction in atherosclerosis
-
Madamanchi NR, Runge MS,. 2007. Mitochondrial dysfunction in atherosclerosis. Circ Res 100: 460-473.
-
(2007)
Circ Res
, vol.100
, pp. 460-473
-
-
Madamanchi, N.R.1
Runge, M.S.2
-
22
-
-
30944449237
-
Differential neuronal expression of manganese superoxide dismutase in Alzheimer's disease
-
Marcus DL, Strafaci JA, Freedman ML,. 2006. Differential neuronal expression of manganese superoxide dismutase in Alzheimer's disease. Med Sci Monit 12: BR8-14.
-
(2006)
Med Sci Monit
, vol.12
-
-
Marcus, D.L.1
Strafaci, J.A.2
Freedman, M.L.3
-
23
-
-
0015523099
-
The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase
-
Misra HP, Fridovich I,. 1972. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 247: 3170-3175.
-
(1972)
J Biol Chem
, vol.247
, pp. 3170-3175
-
-
Misra, H.P.1
Fridovich, I.2
-
24
-
-
79959961108
-
The complex biology of FOXO
-
Monsalve M, Olmos Y,. 2011. The complex biology of FOXO. Curr Drug Targets 12: 1322-1350.
-
(2011)
Curr Drug Targets
, vol.12
, pp. 1322-1350
-
-
Monsalve, M.1
Olmos, Y.2
-
25
-
-
40549116687
-
Protective effect of phlorotannin components phloroglucinol and eckol on radiation-induced intestinal injury in mice
-
Moon C, Kim SH, Kim JC, Hyun JW, Lee NH, Park JW, Shin T,. 2008. Protective effect of phlorotannin components phloroglucinol and eckol on radiation-induced intestinal injury in mice. Phytother Res 22: 238-242.
-
(2008)
Phytother Res
, vol.22
, pp. 238-242
-
-
Moon, C.1
Kim, S.H.2
Kim, J.C.3
Hyun, J.W.4
Lee, N.H.5
Park, J.W.6
Shin, T.7
-
26
-
-
0018749490
-
Role of superoxide dismutase in cancer: A review
-
Oberley LW, Buettner GR,. 1979. Role of superoxide dismutase in cancer: A review. Cancer Res 39: 1141-1149.
-
(1979)
Cancer Res
, vol.39
, pp. 1141-1149
-
-
Oberley, L.W.1
Buettner, G.R.2
-
27
-
-
34548451974
-
Reactive oxygen species in mitochondria-mediated cell death
-
Orrenius S,. 2007. Reactive oxygen species in mitochondria-mediated cell death. Drug Metab Rev 39: 443-455.
-
(2007)
Drug Metab Rev
, vol.39
, pp. 443-455
-
-
Orrenius, S.1
-
28
-
-
0033400541
-
Mitochondrial events in the life and death of animal cells: A brief overview
-
Pedersen PL,. 1999. Mitochondrial events in the life and death of animal cells: A brief overview. J Bioenerg Biomembr 31: 291-304.
-
(1999)
J Bioenerg Biomembr
, vol.31
, pp. 291-304
-
-
Pedersen, P.L.1
-
29
-
-
34249792393
-
Role of mitochondria in non-alcoholic fatty liver disease
-
Pessayre D,. 2007. Role of mitochondria in non-alcoholic fatty liver disease. J Gastroenterol Hepatol 22: S20-S27.
-
(2007)
J Gastroenterol Hepatol
, vol.22
-
-
Pessayre, D.1
-
30
-
-
84861910811
-
Eckol inhibits ultraviolet B-induced cell damage in human keratinocytes via a decrease in oxidative stress
-
Piao MJ, Lee NH, Chae S, Hyun JW,. 2012. Eckol inhibits ultraviolet B-induced cell damage in human keratinocytes via a decrease in oxidative stress. Biol Pharm Bull 35: 873-880.
-
(2012)
Biol Pharm Bull
, vol.35
, pp. 873-880
-
-
Piao, M.J.1
Lee, N.H.2
Chae, S.3
Hyun, J.W.4
-
31
-
-
0027325097
-
2+: Their relationship to apoptosis and oncogenesis
-
2+: Their relationship to apoptosis and oncogenesis. FEBS Lett 325: 104-107.
-
(1993)
FEBS Lett
, vol.325
, pp. 104-107
-
-
Richter, C.1
-
32
-
-
0036867101
-
Inhibitory activity of brown algal phlorotannins against glycosidases from the viscera of the turban shell Turbo cornutus
-
Shibata T, Yamaguchi K, Nagayama K, Kawaguchi S, Nakamura T,. 2002. Inhibitory activity of brown algal phlorotannins against glycosidases from the viscera of the turban shell Turbo cornutus. Eur J Phycol 37: 493-500.
-
(2002)
Eur J Phycol
, vol.37
, pp. 493-500
-
-
Shibata, T.1
Yamaguchi, K.2
Nagayama, K.3
Kawaguchi, S.4
Nakamura, T.5
-
33
-
-
0030582372
-
Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene. A predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's disease
-
Shimoda-Matsubayashi S, Matsumine H, Kobayashi T, Nakagawa-Hattori Y, Shimizu Y, Mizuno Y,. 1996. Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene. A predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's disease. Biochem Biophys Res Commun 226: 561-565.
-
(1996)
Biochem Biophys Res Commun
, vol.226
, pp. 561-565
-
-
Shimoda-Matsubayashi, S.1
Matsumine, H.2
Kobayashi, T.3
Nakagawa-Hattori, Y.4
Shimizu, Y.5
Mizuno, Y.6
-
34
-
-
48049097037
-
Biochemical biomarkers in algae and marine pollution: A review
-
Torres MA, Barros MP, Campos SC, Pinto E, Rajamani S, Sayre RT, Colepicolo P,. 2008. Biochemical biomarkers in algae and marine pollution: A review. Ecotoxicol Environ Saf 71: 1-15.
-
(2008)
Ecotoxicol Environ Saf
, vol.71
, pp. 1-15
-
-
Torres, M.A.1
Barros, M.P.2
Campos, S.C.3
Pinto, E.4
Rajamani, S.5
Sayre, R.T.6
Colepicolo, P.7
-
35
-
-
0037134040
-
DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein
-
Tran H, Brunet A, Grenier JM, Datta SR, Fornace AJ, Jr., DiStefano PS, Chiang LW, Greenberg ME,. 2002. DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science 296: 530-534.
-
(2002)
Science
, vol.296
, pp. 530-534
-
-
Tran, H.1
Brunet, A.2
Grenier, J.M.3
Datta, S.R.4
Fornace, Jr.A.J.5
Distefano, P.S.6
Chiang, L.W.7
Greenberg, M.E.8
-
36
-
-
39849091969
-
Nonalcoholic fatty liver disease and mitochondrial dysfunction
-
Wei Y, Rector RS, Thyfault JP, Ibdah JA,. 2008. Nonalcoholic fatty liver disease and mitochondrial dysfunction. World J Gastroenterol 14: 193-199.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 193-199
-
-
Wei, Y.1
Rector, R.S.2
Thyfault, J.P.3
Ibdah, J.A.4
-
37
-
-
0015848173
-
Superoxide dismutase. Organelle specificity
-
Weisiger RA, Fridovich I,. 1973. Superoxide dismutase. Organelle specificity. J Biol Chem 248: 3582-3592.
-
(1973)
J Biol Chem
, vol.248
, pp. 3582-3592
-
-
Weisiger, R.A.1
Fridovich, I.2
-
38
-
-
48749131954
-
Eckol protects V79-4 lung fibroblast cells against gamma-ray radiation-induced apoptosis via the scavenging of reactive oxygen species and inhibiting of the c-Jun NH(2)-terminal kinase pathway
-
Zhang R, Kang KA, Piao MJ, Ko DO, Wang ZH, Lee IK, Kim BJ, Jeong IY, Shin T, Park JW, Lee NH, Hyun JW,. 2008. Eckol protects V79-4 lung fibroblast cells against gamma-ray radiation-induced apoptosis via the scavenging of reactive oxygen species and inhibiting of the c-Jun NH(2)-terminal kinase pathway. Eur J Pharmacol 591: 114-123.
-
(2008)
Eur J Pharmacol
, vol.591
, pp. 114-123
-
-
Zhang, R.1
Kang, K.A.2
Piao, M.J.3
Ko, D.O.4
Wang, Z.H.5
Lee, I.K.6
Kim, B.J.7
Jeong, I.Y.8
Shin, T.9
Park, J.W.10
Lee, N.H.11
Hyun, J.W.12
-
39
-
-
77954951896
-
Cytoprotective effect of the fruits of Lycium chinense Miller against oxidative stress-induced hepatotoxicity
-
Zhang R, Kang KA, Piao MJ, Kim KC, Kim AD, Chae S, Park JS, Youn UJ, Hyun JW,. 2010. Cytoprotective effect of the fruits of Lycium chinense Miller against oxidative stress-induced hepatotoxicity. J Ethnopharmacol 130: 299-306.
-
(2010)
J Ethnopharmacol
, vol.130
, pp. 299-306
-
-
Zhang, R.1
Kang, K.A.2
Piao, M.J.3
Kim, K.C.4
Kim, A.D.5
Chae, S.6
Park, J.S.7
Youn, U.J.8
Hyun, J.W.9
-
40
-
-
80455176679
-
Applications of post-translational modifications of FoxO family proteins in biological functions
-
Zhao Y, Wang Y, Zhu WG,. 2011. Applications of post-translational modifications of FoxO family proteins in biological functions. J Mol Cell Biol 3: 276-282.
-
(2011)
J Mol Cell Biol
, vol.3
, pp. 276-282
-
-
Zhao, Y.1
Wang, Y.2
Zhu, W.G.3
|