-
1
-
-
41849119497
-
A brief introduction to FOXOlogy
-
Burgering BM. A brief introduction to FOXOlogy. Oncogene 2008; 27:2258-62.
-
(2008)
Oncogene
, vol.27
, pp. 2258-2262
-
-
Burgering, B.M.1
-
2
-
-
0034661826
-
Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues
-
Furuyama T, Nakazawa T, Nakano I, Mori N. Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues. Biochem J 2000; 349:629-34.
-
(2000)
Biochem J
, vol.349
, pp. 629-634
-
-
Furuyama, T.1
Nakazawa, T.2
Nakano, I.3
Mori, N.4
-
4
-
-
41849087003
-
FOXO animal models reveal a variety of diverse roles for FOXO transcription factors
-
Arden KC. FOXO animal models reveal a variety of diverse roles for FOXO transcription factors. Oncogene 2008; 27:2345-50.
-
(2008)
Oncogene
, vol.27
, pp. 2345-2350
-
-
Arden, K.C.1
-
5
-
-
1542267804
-
Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification
-
Hosaka T, Biggs WH, 3rd, Tieu D, Boyer AD, Varki NM, Cavenee WK, et al. Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. Proc Natl Acad Sci USA 2004; 101:2975-80.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2975-2980
-
-
Hosaka, T.1
Biggs III, W.H.2
Tieu, D.3
Boyer, A.D.4
Varki, N.M.5
Cavenee, W.K.6
-
6
-
-
0038152845
-
Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a
-
Castrillon DH, Miao L, Kollipara R, Horner JW, DePinho RA. Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a. Science 2003; 301:215-8.
-
(2003)
Science
, vol.301
, pp. 215-218
-
-
Castrillon, D.H.1
Miao, L.2
Kollipara, R.3
Horner, J.W.4
DePinho, R.A.5
-
7
-
-
53249095869
-
Codependent activators direct myoblast-specific MyoD transcription
-
Hu P, Geles KG, Paik JH, DePinho RA, Tjian R. Codependent activators direct myoblast-specific MyoD transcription. Dev Cell 2008; 15:534-46.
-
(2008)
Dev Cell
, vol.15
, pp. 534-546
-
-
Hu, P.1
Geles, K.G.2
Paik, J.H.3
DePinho, R.A.4
Tjian, R.5
-
8
-
-
33846295218
-
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
-
Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, et al. FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell 2007; 128:309-23.
-
(2007)
Cell
, vol.128
, pp. 309-323
-
-
Paik, J.H.1
Kollipara, R.2
Chu, G.3
Ji, H.4
Xiao, Y.5
Ding, Z.6
-
9
-
-
33846419112
-
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
-
Tothova Z, Kollipara R, Huntly BJ, Lee BH, Castrillon DH, Cullen DE, et al. FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 2007; 128:325-39.
-
(2007)
Cell
, vol.128
, pp. 325-339
-
-
Tothova, Z.1
Kollipara, R.2
Huntly, B.J.3
Lee, B.H.4
Castrillon, D.H.5
Cullen, D.E.6
-
10
-
-
34249281690
-
Stressing the role of FoxO proteins in lifespan and disease
-
van der Horst A, Burgering BM. Stressing the role of FoxO proteins in lifespan and disease. Nat Rev Mol Cell Biol 2007; 8:440-50.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 440-450
-
-
Van Der Horst, A.1
Burgering, B.M.2
-
11
-
-
0036787607
-
Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1
-
Nakae J, Biggs WH, 3rd, Kitamura T, Cavenee WK, Wright CV, Arden KC, et al. Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. Nat Genet 2002; 32:245-53.
-
(2002)
Nat Genet
, vol.32
, pp. 245-253
-
-
Nakae, J.1
Biggs III, W.H.2
Kitamura, T.3
Cavenee, W.K.4
Wright, C.V.5
Arden, K.C.6
-
12
-
-
69049096002
-
p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription
-
Chiacchiera F, Matrone A, Ferrari E, Ingravallo G, Lo Sasso G, Murzilli S, et al. p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription. Cell Death Differ 2009; 16:1203-14.
-
(2009)
Cell Death Differ
, vol.16
, pp. 1203-1214
-
-
Chiacchiera, F.1
Matrone, A.2
Ferrari, E.3
Ingravallo, G.4
Lo Sasso, G.5
Murzilli, S.6
-
13
-
-
70349644002
-
Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism
-
Chiacchiera F, Simone C. Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism. Autophagy 2009; 5:1030-3.
-
(2009)
Autophagy
, vol.5
, pp. 1030-1033
-
-
Chiacchiera, F.1
Simone, C.2
-
15
-
-
77951887477
-
p38α is required for ovarian cancer cell metabolism and survival
-
in press
-
Matrone A, Grossi V, Chiacchiera F, Fina E, Cappellari M, Loverro G, et al. p38α is required for ovarian cancer cell metabolism and survival. Int J Gynecol Cancer 2010; in press.
-
(2010)
Int J Gynecol Cancer
-
-
Matrone, A.1
Grossi, V.2
Chiacchiera, F.3
Fina, E.4
Cappellari, M.5
Loverro, G.6
-
16
-
-
41849108086
-
Many forks in the path: Cycling with FoxO
-
Ho KK, Myatt SS, Lam EW. Many forks in the path: cycling with FoxO. Oncogene 2008; 27:2300-11.
-
(2008)
Oncogene
, vol.27
, pp. 2300-2311
-
-
Ho, K.K.1
Myatt, S.S.2
Lam, E.W.3
-
17
-
-
33745841375
-
FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal
-
You H, Pellegrini M, Tsuchihara K, Yamamoto K, Hacker G, Erlacher M, et al. FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal. J Exp Med 2006; 203:1657-63.
-
(2006)
J Exp Med
, vol.203
, pp. 1657-1663
-
-
You, H.1
Pellegrini, M.2
Tsuchihara, K.3
Yamamoto, K.4
Hacker, G.5
Erlacher, M.6
-
18
-
-
0036839685
-
Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D
-
Schmidt M, Fernandez de Mattos S, van der Horst A, Klompmaker R, Kops GJ, Lam EW, et al. Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D. Mol Cell Biol 2002; 22:7842-52.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7842-7852
-
-
Schmidt, M.1
Fernandez De Mattos, S.2
Van Der Horst, A.3
Klompmaker, R.4
Kops, G.J.5
Lam, E.W.6
-
19
-
-
34347357584
-
Induction of Mxi1-SRalpha by FOXO3a contributes to repression of Myc-dependent gene expression
-
Delpuech O, Griffiths B, East P, Essafi A, Lam EW, Burgering B, et al. Induction of Mxi1-SRalpha by FOXO3a contributes to repression of Myc-dependent gene expression. Mol Cell Biol 2007; 27:4917-30.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4917-4930
-
-
Delpuech, O.1
Griffiths, B.2
East, P.3
Essafi, A.4
Lam, E.W.5
Burgering, B.6
-
20
-
-
36448940798
-
FoxO3 controls autophagy in skeletal muscle in vivo
-
Mammucari C, Milan G, Romanello V, Masiero E, Rudolf R, Del Piccolo P, et al. FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab 2007; 6:458-71.
-
(2007)
Cell Metab
, vol.6
, pp. 458-471
-
-
Mammucari, C.1
Milan, G.2
Romanello, V.3
Masiero, E.4
Rudolf, R.5
Del Piccolo, P.6
-
21
-
-
36448968532
-
FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells
-
Zhao J, Brault JJ, Schild A, Cao P, Sandri M, Schiaffino S, et al. FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab 2007; 6:472-83.
-
(2007)
Cell Metab
, vol.6
, pp. 472-483
-
-
Zhao, J.1
Brault, J.J.2
Schild, A.3
Cao, P.4
Sandri, M.5
Schiaffino, S.6
-
22
-
-
34249096247
-
Gene expression profiling identifies FKBP39 as an inhibitor of autophagy in larval Drosophila fat body
-
Juhász G, Puskás LG, Komonyi O, Erdi B, Maróy P, Neufeld TP, Sass M. Gene expression profiling identifies FKBP39 as an inhibitor of autophagy in larval Drosophila fat body. Cell Death Differ 2007; 14:1181-90.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1181-1190
-
-
Juhász, G.1
Puskás, L.G.2
Komonyi, O.3
Erdi, B.4
Maróy, P.5
Neufeld, T.P.6
Sass, M.7
-
23
-
-
11144357466
-
IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
-
Hu MC, Lee DF, Xia W, Golfman LS, Ou-Yang F, Yang JY, et al. IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell 2004; 117:225-37.
-
(2004)
Cell
, vol.117
, pp. 225-237
-
-
Hu, M.C.1
Lee, D.F.2
Xia, W.3
Golfman, L.S.4
Ou-Yang, F.5
Yang, J.Y.6
-
24
-
-
38849139580
-
ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation
-
Yang JY, Zong CS, Xia W, Yamaguchi H, Ding Q, Xie X, et al. ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation. Nat Cell Biol 2008; 10:138-48.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 138-148
-
-
Yang, J.Y.1
Zong, C.S.2
Xia, W.3
Yamaguchi, H.4
Ding, Q.5
Xie, X.6
-
25
-
-
36549065662
-
FoxO tumor suppressors and BCR-ABL-induced leukemia: A matter of evasion of apoptosis
-
Jagani Z, Singh A, Khosravi-Far R. FoxO tumor suppressors and BCR-ABL-induced leukemia: a matter of evasion of apoptosis. Biochim Biophys Acta 2008; 1785:63-84.
-
(2008)
Biochim Biophys Acta
, vol.1785
, pp. 63-84
-
-
Jagani, Z.1
Singh, A.2
Khosravi-Far, R.3
-
26
-
-
33745316089
-
Identification of a tumour suppressor network opposing nuclear Akt function
-
Trotman LC, Alimonti A, Scaglioni PP, Koutcher JA, Cordon-Cardo C, Pandolfi PP. Identification of a tumour suppressor network opposing nuclear Akt function. Nature 2006; 441:523-7.
-
(2006)
Nature
, vol.441
, pp. 523-527
-
-
Trotman, L.C.1
Alimonti, A.2
Scaglioni, P.P.3
Koutcher, J.A.4
Cordon-Cardo, C.5
Pandolfi, P.P.6
-
27
-
-
36849061266
-
Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity
-
Kikuno N, Shiina H, Urakami S, Kawamoto K, Hirata H, Tanaka Y, et al. Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity. Oncogene 2007; 26:7647-55.
-
(2007)
Oncogene
, vol.26
, pp. 7647-7655
-
-
Kikuno, N.1
Shiina, H.2
Urakami, S.3
Kawamoto, K.4
Hirata, H.5
Tanaka, Y.6
-
28
-
-
47949126042
-
FOXO3a mediates the androgen-dependent regulation of FLIP and contributes to TRAIL-induced apoptosis of LNCaP cells
-
Cornforth AN, Davis JS, Khanifar E, Nastiuk KL, Krolewski JJ. FOXO3a mediates the androgen-dependent regulation of FLIP and contributes to TRAIL-induced apoptosis of LNCaP cells. Oncogene 2008; 27:4422-33.
-
(2008)
Oncogene
, vol.27
, pp. 4422-4433
-
-
Cornforth, A.N.1
Davis, J.S.2
Khanifar, E.3
Nastiuk, K.L.4
Krolewski, J.J.5
-
29
-
-
1642332084
-
Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation
-
Seoane J, Le HV, Shen L, Anderson SA, Massagué J. Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation. Cell 2004; 117:211-23.
-
(2004)
Cell
, vol.117
, pp. 211-223
-
-
Seoane, J.1
Le, H.V.2
Shen, L.3
Anderson, S.A.4
Massagué, J.5
-
30
-
-
34848861463
-
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor
-
Greer EL, Oskoui PR, Banko MR, Maniar JM, Gygi MP, Gygi SP, et al. The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J Biol Chem 2007; 282:30107-19.
-
(2007)
J Biol Chem
, vol.282
, pp. 30107-30119
-
-
Greer, E.L.1
Oskoui, P.R.2
Banko, M.R.3
Maniar, J.M.4
Gygi, M.P.5
Gygi, S.P.6
-
31
-
-
67749111502
-
The LKB1-AMPK pathway: Metabolism and growth control in tumour suppression
-
Shackelford DB, Shaw RJ. The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat Rev Cancer 2009; 9:563-75.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 563-575
-
-
Shackelford, D.B.1
Shaw, R.J.2
-
32
-
-
14444272759
-
STK11 mutations in Peutz-Jeghers syndrome and sporadic colon cancer
-
Resta N, Simone C, Mareni C, Montera M, Gentile M, Susca F, et al. STK11 mutations in Peutz-Jeghers syndrome and sporadic colon cancer. Cancer Res 1998; 58:4799-801.
-
(1998)
Cancer Res
, vol.58
, pp. 4799-4801
-
-
Resta, N.1
Simone, C.2
Mareni, C.3
Montera, M.4
Gentile, M.5
Susca, F.6
-
33
-
-
58649110598
-
Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation
-
Zheng B, Jeong JH, Asara JM, Yuan YY, Granter SR, Chin L, et al. Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation. Mol Cell 2009; 33:237-47.
-
(2009)
Mol Cell
, vol.33
, pp. 237-247
-
-
Zheng, B.1
Jeong, J.H.2
Asara, J.M.3
Yuan, Y.Y.4
Granter, S.R.5
Chin, L.6
-
34
-
-
33748153690
-
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth
-
Inoki K, Ouyang H, Zhu T, Lindvall C, Wang Y, Zhang X, et al. TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell 2006; 126:955-68.
-
(2006)
Cell
, vol.126
, pp. 955-968
-
-
Inoki, K.1
Ouyang, H.2
Zhu, T.3
Lindvall, C.4
Wang, Y.5
Zhang, X.6
-
35
-
-
66149129259
-
Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells
-
Zhou J, Huang W, Tao R, Ibaragi S, Lan F, Ido Y, et al. Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells. Oncogene 2009; 28:1993-2002.
-
(2009)
Oncogene
, vol.28
, pp. 1993-2002
-
-
Zhou, J.1
Huang, W.2
Tao, R.3
Ibaragi, S.4
Lan, F.5
Ido, Y.6
-
37
-
-
43049121395
-
Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt
-
Fulco M, Cen Y, Zhao P, Hoffman EP, McBurney MW, Sauve AA, et al. Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Dev Cell 2008; 14:661-73.
-
(2008)
Dev Cell
, vol.14
, pp. 661-673
-
-
Fulco, M.1
Cen, Y.2
Zhao, P.3
Hoffman, E.P.4
McBurney, M.W.5
Sauve, A.A.6
-
38
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004; 303:2011-5.
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
-
39
-
-
70349633673
-
Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin
-
Li XN, Song J, Zhang L, LeMaire SA, Hou X, Zhang C, et al. Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin. Diabetes 2009; 58:2246-57.
-
(2009)
Diabetes
, vol.58
, pp. 2246-2257
-
-
Li, X.N.1
Song, J.2
Zhang, L.3
LeMaire, S.A.4
Hou, X.5
Zhang, C.6
-
40
-
-
67650882500
-
AMPKalpha1 regulates the antioxidant status of vascular endothelial cells
-
Colombo SL, Moncada S. AMPKalpha1 regulates the antioxidant status of vascular endothelial cells. Biochem J 2009; 421:163-9.
-
(2009)
Biochem J
, vol.421
, pp. 163-169
-
-
Colombo, S.L.1
Moncada, S.2
-
41
-
-
0002458132
-
The effect of retarded growth upon the length of life span and upon the ultimate body size
-
McCay CM, Crowell MF, Maynard LA. The effect of retarded growth upon the length of life span and upon the ultimate body size. J Nutr 1935; 10:63-79.
-
(1935)
J Nutr
, vol.10
, pp. 63-79
-
-
McCay, C.M.1
Crowell, M.F.2
Maynard, L.A.3
-
42
-
-
22744452215
-
Food restriction, evolution and ageing
-
Kirkwood TB, Shanley DP. Food restriction, evolution and ageing. Mech Ageing Dev 2005; 126:1011-6.
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 1011-1016
-
-
Kirkwood, T.B.1
Shanley, D.P.2
-
43
-
-
2342647592
-
Longterm calorie restriction is highly effective in reducing the risk for atherosclerosis in humans
-
Fontana L, Meyer TE, Klein S, Holloszy JO. Longterm calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc Natl Acad Sci USA 2004; 101:6659-63.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6659-6663
-
-
Fontana, L.1
Meyer, T.E.2
Klein, S.3
Holloszy, J.O.4
-
44
-
-
19944427435
-
Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease
-
Maswood N, Young J, Tilmont E, Zhang Z, Gash DM, Gerhardt GA, et al. Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease. Proc Natl Acad Sci USA 2004; 101:18171-6.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 18171-18176
-
-
Maswood, N.1
Young, J.2
Tilmont, E.3
Zhang, Z.4
Gash, D.M.5
Gerhardt, G.A.6
-
45
-
-
1542377615
-
Caloric restriction and incidence of breast cancer
-
Michels KB, Ekbom A. Caloric restriction and incidence of breast cancer. Jama 2004; 291:1226-30.
-
(2004)
Jama
, vol.291
, pp. 1226-1230
-
-
Michels, K.B.1
Ekbom, A.2
-
46
-
-
72949117234
-
Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila
-
Epub ahead of print
-
Grandison RC, Piper MD, Partridge L. Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila. Nature 2009; Epub ahead of print.
-
(2009)
Nature
-
-
Grandison, R.C.1
Piper, M.D.2
Partridge, L.3
-
47
-
-
63549108476
-
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans
-
Greer EL, Brunet A. Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans. Aging Cell 2009; 8:113-27.
-
(2009)
Aging Cell
, vol.8
, pp. 113-127
-
-
Greer, E.L.1
Brunet, A.2
-
48
-
-
22744434107
-
Calories do not explain extension of life span by dietary restriction in Drosophila
-
Mair W, Piper MD, Partridge L. Calories do not explain extension of life span by dietary restriction in Drosophila. PLoS Biol 2005; 3:223.
-
(2005)
PLoS Biol
, vol.3
, pp. 223
-
-
Mair, W.1
Piper, M.D.2
Partridge, L.3
-
49
-
-
38349103636
-
Separating cause from effect: How does insulin/IGF signalling control lifespan in worms, flies and mice?
-
Piper MD, Selman C, McElwee JJ, Partridge L. Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice? J Intern Med 2008; 263:179-91.
-
(2008)
J Intern Med
, vol.263
, pp. 179-191
-
-
Piper, M.D.1
Selman, C.2
McElwee, J.J.3
Partridge, L.4
-
50
-
-
47049101814
-
Dietary composition specifies consumption, obesity and lifespan in Drosophila melanogaster
-
Skorupa DA, Dervisefendic A, Zwiener J, Pletcher SD. Dietary composition specifies consumption, obesity and lifespan in Drosophila melanogaster. Aging Cell 2008; 7:478-90.
-
(2008)
Aging Cell
, vol.7
, pp. 478-490
-
-
Skorupa, D.A.1
Dervisefendic, A.2
Zwiener, J.3
Pletcher, S.D.4
-
51
-
-
14844293962
-
The role of insulin and IGF-1 signaling in longevity
-
Katic M, Kahn CR. The role of insulin and IGF-1 signaling in longevity. Cell Mol Life Sci 2005; 62:320-43.
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 320-343
-
-
Katic, M.1
Kahn, C.R.2
-
52
-
-
48549091164
-
Dietary energy restriction modulates the activity of AMP-activated protein kinase, Akt and mammalian target of rapamycin in mammary carcinomas, mammary gland, and liver
-
Jiang W, Zhu Z, Thompson HJ. Dietary energy restriction modulates the activity of AMP-activated protein kinase, Akt and mammalian target of rapamycin in mammary carcinomas, mammary gland, and liver. Cancer Res 2008; 68:5492-9.
-
(2008)
Cancer Res
, vol.68
, pp. 5492-5499
-
-
Jiang, W.1
Zhu, Z.2
Thompson, H.J.3
-
53
-
-
68649105257
-
AMP-activated protein kinase and FoxO transcription factors in dietary restriction-induced longevity
-
Greer EL, Banko MR, Brunet A. AMP-activated protein kinase and FoxO transcription factors in dietary restriction-induced longevity. Ann NY Acad Sci 2009; 1170:688-92.
-
(2009)
Ann NY Acad Sci
, vol.1170
, pp. 688-692
-
-
Greer, E.L.1
Banko, M.R.2
Brunet, A.3
-
54
-
-
33750619348
-
Glucose metabolism and cancer
-
Shaw RJ. Glucose metabolism and cancer. Curr Opin Cell Biol 2006; 18:598-608.
-
(2006)
Curr Opin Cell Biol
, vol.18
, pp. 598-608
-
-
Shaw, R.J.1
-
55
-
-
67650480092
-
mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome
-
Shackelford DB, Vasquez DS, Corbeil J, Wu S, Leblanc M, Wu CL, et al. mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome. Proc Natl Acad Sci USA 2009; 106:11137-42.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 11137-11142
-
-
Shackelford, D.B.1
Vasquez, D.S.2
Corbeil, J.3
Wu, S.4
Leblanc, M.5
Wu, C.L.6
-
56
-
-
61349137083
-
A new fork for clinical application: Targeting forkhead transcription factors in cancer
-
Yang JY, Hung MC. A new fork for clinical application: targeting forkhead transcription factors in cancer. Clin Cancer Res 2009; 15:752-7.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 752-757
-
-
Yang, J.Y.1
Hung, M.C.2
-
57
-
-
69249162223
-
Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth
-
Kisfalvi K, Eibl G, Sinnett-Smith J, Rozengurt E. Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. Cancer Res 2009; 69:6539-45.
-
(2009)
Cancer Res
, vol.69
, pp. 6539-6545
-
-
Kisfalvi, K.1
Eibl, G.2
Sinnett-Smith, J.3
Rozengurt, E.4
-
58
-
-
44449103256
-
Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
-
Huang X, Wullschleger S, Shpiro N, McGuire VA, Sakamoto K, Woods YL, et al. Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice. Biochem J 2008; 412:211-21.
-
(2008)
Biochem J
, vol.412
, pp. 211-221
-
-
Huang, X.1
Wullschleger, S.2
Shpiro, N.3
McGuire, V.A.4
Sakamoto, K.5
Woods, Y.L.6
-
59
-
-
20444461067
-
Metformin and reduced risk of cancer in diabetic patients
-
Evans JM, Donnelly LA, Emslie-Smith AM, Alessi DR, Morris AD. Metformin and reduced risk of cancer in diabetic patients. BMJ 2005; 330:1304-5.
-
(2005)
BMJ
, vol.330
, pp. 1304-1305
-
-
Evans, J.M.1
Donnelly, L.A.2
Emslie-Smith, A.M.3
Alessi, D.R.4
Morris, A.D.5
-
60
-
-
69549097703
-
New users of metformin are at low risk of incident cancer: A cohort study among people with type 2 diabetes
-
Libby G, Donnelly LA, Donnan PT, Alessi DR, Morris AD, Evans JM. New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes. Diabetes Care 2009; 32:1620-5.
-
(2009)
Diabetes Care
, vol.32
, pp. 1620-1625
-
-
Libby, G.1
Donnelly, L.A.2
Donnan, P.T.3
Alessi, D.R.4
Morris, A.D.5
Evans, J.M.6
-
61
-
-
60549096247
-
Akt-dependent and -independent mechanisms of mTOR regulation in cancer
-
Memmott RM, Dennis PA. Akt-dependent and -independent mechanisms of mTOR regulation in cancer. Cell Signal 2009; 21:656-64.
-
(2009)
Cell Signal
, vol.21
, pp. 656-664
-
-
Memmott, R.M.1
Dennis, P.A.2
|