A functional and putative physiological role of calcitriol in Patched1/Smoothened interaction

Journal of Biological Chemistry

Volumn 290, Issue 32, 2015, Pages 19614-19628

  Linder, Benedikt ^a   Weber, Susanne ^b   Dittmann, Kai ^a   Adamski, Jerzy ^b   Hahn, Heidi ^a   Uhmann, Anja ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY;

CYSTEINE-RICH DOMAINS; DIRECT INTERACTIONS; ITRACONAZOLE; PHYSIOLOGICAL ROLES; SIGNAL TRANSMITTING; VITAMIN-D;

FINANCIAL MARKETS;

CALCITRIOL; COLECALCIFEROL 24 HYDROXYLASE; ITRACONAZOLE; PROTEIN PATCHED 1; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; CELL SURFACE RECEPTOR; G PROTEIN COUPLED RECEPTOR; LUCIFERASE; PATCHED RECEPTORS; PROTEIN BINDING; SMO PROTEIN, HUMAN;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG MECHANISM; DRUG POTENTIATION; ENZYME INHIBITION; EXTRACELLULAR SPACE; GENE EXPRESSION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PTCH GENE; SIGNAL TRANSDUCTION; VITAMIN METABOLISM; ANIMAL; CELL LINE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; KERATINOCYTE; METABOLISM; PROTEIN TERTIARY STRUCTURE; REPORTER GENE;

ERINACEIDAE;

ANIMALS; BINDING SITES; CALCITRIOL; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; GENE EXPRESSION REGULATION; GENES, REPORTER; HEK293 CELLS; HUMANS; ITRACONAZOLE; KERATINOCYTES; LUCIFERASES; MICE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84939621422     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.646141     Document Type: Article

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