메뉴 건너뛰기




Volumn 412, Issue , 2015, Pages 290-301

Activin A, B and AB decrease progesterone production by down-regulating StAR in human granulosa cells

Author keywords

Activin A; Activin AB; Activin B; Human granulosa cells; Progesterone; StAR

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXY 1 METHYLTETRALIN; 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; ACTIVIN; ACTIVIN A; ACTIVIN AB; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYELOPID; PROTEIN KINASE B; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; UNCLASSIFIED DRUG; ACTIVIN RECEPTOR 1; ACVR1B PROTEIN, HUMAN; PHOSPHOPROTEIN; PROGESTERONE; PROTEIN SERINE THREONINE KINASE; SMAD2 PROTEIN, HUMAN; SMAD3 PROTEIN, HUMAN; TGF-BETA TYPE I RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

EID: 84939469540     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2015.05.016     Document Type: Article
Times cited : (43)

References (41)
  • 1
    • 0032402288 scopus 로고    scopus 로고
    • Activin A stimulates meiotic maturation of human oocytes and modulates granulosa cell steroidogenesis in vitro
    • Alak B.M., Coskun S., Friedman C.I., Kennard E.A., Kim M.H., Seifer D.B. Activin A stimulates meiotic maturation of human oocytes and modulates granulosa cell steroidogenesis in vitro. Fertil. Steril 1998, 70:1126-1130.
    • (1998) Fertil. Steril , vol.70 , pp. 1126-1130
    • Alak, B.M.1    Coskun, S.2    Friedman, C.I.3    Kennard, E.A.4    Kim, M.H.5    Seifer, D.B.6
  • 2
    • 33750402400 scopus 로고    scopus 로고
    • Activin B can signal through both ALK4 and ALK7 in gonadotrope cells
    • Bernard D.J., Lee K.B., Santos M.M. Activin B can signal through both ALK4 and ALK7 in gonadotrope cells. Reprod. Biol. Endocrinol 2006, 4:52.
    • (2006) Reprod. Biol. Endocrinol , vol.4 , pp. 52
    • Bernard, D.J.1    Lee, K.B.2    Santos, M.M.3
  • 3
    • 34247539528 scopus 로고    scopus 로고
    • A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling
    • Brown K.A., Pietenpol J.A., Moses H.L. A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling. J. Cell. Biochem 2007, 101:9-33.
    • (2007) J. Cell. Biochem , vol.101 , pp. 9-33
    • Brown, K.A.1    Pietenpol, J.A.2    Moses, H.L.3
  • 5
    • 84899843876 scopus 로고    scopus 로고
    • Oocyte-derived BMP15 but not GDF9 down-regulates connexin43 expression and decreases gap junction intercellular communication activity in immortalized human granulosa cells
    • Chang H.M., Cheng J.C., Taylor E., Leung P.C. Oocyte-derived BMP15 but not GDF9 down-regulates connexin43 expression and decreases gap junction intercellular communication activity in immortalized human granulosa cells. Mol. Hum. Reprod 2014, 20:373-383.
    • (2014) Mol. Hum. Reprod , vol.20 , pp. 373-383
    • Chang, H.M.1    Cheng, J.C.2    Taylor, E.3    Leung, P.C.4
  • 6
    • 84924984415 scopus 로고    scopus 로고
    • Recombinant BMP4 and BMP7 down-regulate pentraxin 3 in human granulosa cells
    • jc20142496
    • Chang H.M., Cheng J.C., Fang L., Qiu X., Klausen C., Taylor E.L., et al. Recombinant BMP4 and BMP7 down-regulate pentraxin 3 in human granulosa cells. J. Clin. Endocrinol. Metab 2015, 100:E365-E374. jc20142496.
    • (2015) J. Clin. Endocrinol. Metab , vol.100 , pp. E365-E374
    • Chang, H.M.1    Cheng, J.C.2    Fang, L.3    Qiu, X.4    Klausen, C.5    Taylor, E.L.6
  • 7
    • 84922222110 scopus 로고    scopus 로고
    • Recombinant BMP4 and BMP7 increase activin A production by up-regulating inhibin betaA subunit and furin expression in human granulosa-lutein cells
    • jc20143026
    • Chang H.M., Cheng J.C., Klausen C., Leung P.C. Recombinant BMP4 and BMP7 increase activin A production by up-regulating inhibin betaA subunit and furin expression in human granulosa-lutein cells. J. Clin. Endocrinol. Metab 2015, 100:E375-E386. jc20143026.
    • (2015) J. Clin. Endocrinol. Metab , vol.100 , pp. E375-E386
    • Chang, H.M.1    Cheng, J.C.2    Klausen, C.3    Leung, P.C.4
  • 9
    • 33747597788 scopus 로고    scopus 로고
    • Activin inhibits the human Pit-1 gene promoter through the p38 kinase pathway in a Smad-independent manner
    • de Guise C., Lacerte A., Rafiei S., Reynaud R., Roy M., Brue T., et al. Activin inhibits the human Pit-1 gene promoter through the p38 kinase pathway in a Smad-independent manner. Endocrinology 2006, 147:4351-4362.
    • (2006) Endocrinology , vol.147 , pp. 4351-4362
    • de Guise, C.1    Lacerte, A.2    Rafiei, S.3    Reynaud, R.4    Roy, M.5    Brue, T.6
  • 10
    • 0033602186 scopus 로고    scopus 로고
    • A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3
    • Dennler S., Huet S., Gauthier J.M. A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3. Oncogene 1999, 18:1643-1648.
    • (1999) Oncogene , vol.18 , pp. 1643-1648
    • Dennler, S.1    Huet, S.2    Gauthier, J.M.3
  • 11
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • Derynck R., Zhang Y.E. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 2003, 425:577-584.
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 13
    • 0036212281 scopus 로고    scopus 로고
    • Expression and localization of activin receptors, Smads, and beta glycan to the postnatal rat ovary
    • Drummond A.E., Le M.T., Ethier J.F., Dyson M., Findlay J.K. Expression and localization of activin receptors, Smads, and beta glycan to the postnatal rat ovary. Endocrinology 2002, 143:1423-1433.
    • (2002) Endocrinology , vol.143 , pp. 1423-1433
    • Drummond, A.E.1    Le, M.T.2    Ethier, J.F.3    Dyson, M.4    Findlay, J.K.5
  • 15
    • 0030989636 scopus 로고    scopus 로고
    • Development, validation and application of a two-site enzyme-linked immunosorbent assay for activin-AB
    • Evans L.W., Muttukrishna S., Knight P.G., Groome N.P. Development, validation and application of a two-site enzyme-linked immunosorbent assay for activin-AB. J. Endocrinol 1997, 153:221-230.
    • (1997) J. Endocrinol , vol.153 , pp. 221-230
    • Evans, L.W.1    Muttukrishna, S.2    Knight, P.G.3    Groome, N.P.4
  • 16
    • 84910020605 scopus 로고    scopus 로고
    • TGF-beta1 downregulates StAR expression and decreases progesterone production through Smad3 and ERK1/2 signaling pathways in human granulosa cells
    • Fang L., Chang H.M., Cheng J.C., Leung P.C., Sun Y.P. TGF-beta1 downregulates StAR expression and decreases progesterone production through Smad3 and ERK1/2 signaling pathways in human granulosa cells. J. Clin. Endocrinol. Metab 2014, 99:E2234-E2243.
    • (2014) J. Clin. Endocrinol. Metab , vol.99 , pp. E2234-E2243
    • Fang, L.1    Chang, H.M.2    Cheng, J.C.3    Leung, P.C.4    Sun, Y.P.5
  • 17
    • 0036085519 scopus 로고    scopus 로고
    • Activin A, estradiol, and free insulin-like growth factor I in follicular fluid preceding the experimental assumption of follicle dominance in cattle
    • Ginther O.J., Beg M.A., Bergfelt D.R., Kot K. Activin A, estradiol, and free insulin-like growth factor I in follicular fluid preceding the experimental assumption of follicle dominance in cattle. Biol. Reprod 2002, 67:14-19.
    • (2002) Biol. Reprod , vol.67 , pp. 14-19
    • Ginther, O.J.1    Beg, M.A.2    Bergfelt, D.R.3    Kot, K.4
  • 18
    • 33244482452 scopus 로고    scopus 로고
    • Bovine follicle development is associated with divergent changes in activin-A, inhibin-A and follistatin and the relative abundance of different follistatin isoforms in follicular fluid
    • Glister C., Groome N.P., Knight P.G. Bovine follicle development is associated with divergent changes in activin-A, inhibin-A and follistatin and the relative abundance of different follistatin isoforms in follicular fluid. J. Endocrinol 2006, 188:215-225.
    • (2006) J. Endocrinol , vol.188 , pp. 215-225
    • Glister, C.1    Groome, N.P.2    Knight, P.G.3
  • 19
    • 0037351880 scopus 로고    scopus 로고
    • The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly
    • Greenwald J., Groppe J., Gray P., Wiater E., Kwiatkowski W., Vale W., et al. The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly. Mol. Cell 2003, 11:605-617.
    • (2003) Mol. Cell , vol.11 , pp. 605-617
    • Greenwald, J.1    Groppe, J.2    Gray, P.3    Wiater, E.4    Kwiatkowski, W.5    Vale, W.6
  • 20
    • 0032521185 scopus 로고    scopus 로고
    • The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse
    • Gu Z., Nomura M., Simpson B.B., Lei H., Feijen A., van den Eijnden-van Raaij J., et al. The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse. Genes Dev 1998, 12:844-857.
    • (1998) Genes Dev , vol.12 , pp. 844-857
    • Gu, Z.1    Nomura, M.2    Simpson, B.B.3    Lei, H.4    Feijen, A.5    van den Eijnden-van Raaij, J.6
  • 21
    • 0027239557 scopus 로고
    • Inhibin, activin, and follistatin. Potential roles in ovarian physiology
    • Hillier S.G., Miro F. Inhibin, activin, and follistatin. Potential roles in ovarian physiology. Ann. N. Y. Acad. Sci 1993, 687:29-38.
    • (1993) Ann. N. Y. Acad. Sci , vol.687 , pp. 29-38
    • Hillier, S.G.1    Miro, F.2
  • 22
    • 0036085920 scopus 로고    scopus 로고
    • SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
    • Inman G.J., Nicolas F.J., Callahan J.F., Harling J.D., Gaster L.M., Reith A.D., et al. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol. Pharmacol 2002, 62:65-74.
    • (2002) Mol. Pharmacol , vol.62 , pp. 65-74
    • Inman, G.J.1    Nicolas, F.J.2    Callahan, J.F.3    Harling, J.D.4    Gaster, L.M.5    Reith, A.D.6
  • 23
    • 0035058474 scopus 로고    scopus 로고
    • Potential local regulatory functions of inhibins, activins and follistatin in the ovary
    • Knight P.G., Glister C. Potential local regulatory functions of inhibins, activins and follistatin in the ovary. Reproduction 2001, 121:503-512.
    • (2001) Reproduction , vol.121 , pp. 503-512
    • Knight, P.G.1    Glister, C.2
  • 25
    • 84910017322 scopus 로고    scopus 로고
    • Activin A, B, and AB increase human trophoblast cell invasion by up-regulating N-cadherin
    • Li Y., Klausen C., Cheng J.C., Zhu H., Leung P.C. Activin A, B, and AB increase human trophoblast cell invasion by up-regulating N-cadherin. J. Clin. Endocrinol. Metab 2014, 99:E2216-E2225.
    • (2014) J. Clin. Endocrinol. Metab , vol.99 , pp. E2216-E2225
    • Li, Y.1    Klausen, C.2    Cheng, J.C.3    Zhu, H.4    Leung, P.C.5
  • 26
    • 0030200118 scopus 로고    scopus 로고
    • Long-term growth and steroidogenic potential of human granulosa-lutein cells immortalized with SV40 large T antigen
    • Lie B.L., Leung E., Leung P.C., Auersperg N. Long-term growth and steroidogenic potential of human granulosa-lutein cells immortalized with SV40 large T antigen. Mol. Cell. Endocrinol 1996, 120:169-176.
    • (1996) Mol. Cell. Endocrinol , vol.120 , pp. 169-176
    • Lie, B.L.1    Leung, E.2    Leung, P.C.3    Auersperg, N.4
  • 27
    • 0031685620 scopus 로고    scopus 로고
    • TGF-beta signal transduction
    • Massague J. TGF-beta signal transduction. Annu. Rev. Biochem 1998, 67:753-791.
    • (1998) Annu. Rev. Biochem , vol.67 , pp. 753-791
    • Massague, J.1
  • 28
    • 0034678908 scopus 로고    scopus 로고
    • Transcriptional control by the TGF-beta/Smad signaling system
    • Massague J., Wotton D. Transcriptional control by the TGF-beta/Smad signaling system. EMBO J. 2000, 19:1745-1754.
    • (2000) EMBO J. , vol.19 , pp. 1745-1754
    • Massague, J.1    Wotton, D.2
  • 29
    • 0028929864 scopus 로고
    • Different phenotypes for mice deficient in either activins or activin receptor type II
    • Matzuk M.M., Kumar T.R., Bradley A. Different phenotypes for mice deficient in either activins or activin receptor type II. Nature 1995, 374:356-360.
    • (1995) Nature , vol.374 , pp. 356-360
    • Matzuk, M.M.1    Kumar, T.R.2    Bradley, A.3
  • 30
    • 0025790153 scopus 로고
    • Development-related effects of recombinant activin on steroid synthesis in rat granulosa cells
    • Miro F., Smyth C.D., Hillier S.G. Development-related effects of recombinant activin on steroid synthesis in rat granulosa cells. Endocrinology 1991, 129:3388-3394.
    • (1991) Endocrinology , vol.129 , pp. 3388-3394
    • Miro, F.1    Smyth, C.D.2    Hillier, S.G.3
  • 31
    • 0029834358 scopus 로고    scopus 로고
    • Changes in peripheral serum levels of total activin A during the human menstrual cycle and pregnancy
    • Muttukrishna S., Fowler P.A., George L., Groome N.P., Knight P.G. Changes in peripheral serum levels of total activin A during the human menstrual cycle and pregnancy. J. Clin. Endocrinol. Metab 1996, 81:3328-3334.
    • (1996) J. Clin. Endocrinol. Metab , vol.81 , pp. 3328-3334
    • Muttukrishna, S.1    Fowler, P.A.2    George, L.3    Groome, N.P.4    Knight, P.G.5
  • 32
    • 0030238387 scopus 로고    scopus 로고
    • Transgenic mice in the analysis of reproductive development and function
    • Nishimori K., Matzuk M.M. Transgenic mice in the analysis of reproductive development and function. Rev. Reprod 1996, 1:203-212.
    • (1996) Rev. Reprod , vol.1 , pp. 203-212
    • Nishimori, K.1    Matzuk, M.M.2
  • 33
    • 0035827581 scopus 로고    scopus 로고
    • Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts
    • Piek E., Ju W.J., Heyer J., Escalante-Alcalde D., Stewart C.L., Weinstein M., et al. Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts. J. Biol. Chem 2001, 276:19945-19953.
    • (2001) J. Biol. Chem , vol.276 , pp. 19945-19953
    • Piek, E.1    Ju, W.J.2    Heyer, J.3    Escalante-Alcalde, D.4    Stewart, C.L.5    Weinstein, M.6
  • 35
    • 0027482490 scopus 로고
    • Expression of inhibin/activin subunits and follistatin messenger ribonucleic acids and proteins in ovarian follicles and the corpus luteum during the human menstrual cycle
    • Roberts V.J., Barth S., el-Roeiy A., Yen S.S. Expression of inhibin/activin subunits and follistatin messenger ribonucleic acids and proteins in ovarian follicles and the corpus luteum during the human menstrual cycle. J. Clin. Endocrinol. Metab 1993, 77:1402-1410.
    • (1993) J. Clin. Endocrinol. Metab , vol.77 , pp. 1402-1410
    • Roberts, V.J.1    Barth, S.2    el-Roeiy, A.3    Yen, S.S.4
  • 36
    • 0032483544 scopus 로고    scopus 로고
    • Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling
    • Shi Y., Wang Y.F., Jayaraman L., Yang H., Massague J., Pavletich N.P. Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling. Cell 1998, 94:585-594.
    • (1998) Cell , vol.94 , pp. 585-594
    • Shi, Y.1    Wang, Y.F.2    Jayaraman, L.3    Yang, H.4    Massague, J.5    Pavletich, N.P.6
  • 37
    • 0031692312 scopus 로고    scopus 로고
    • Characterization of inhibin/activin subunit, activin receptor, and follistatin messenger ribonucleic acid in human and mouse oocytes: evidence for activin's paracrine signaling from granulosa cells to oocytes
    • Sidis Y., Fujiwara T., Leykin L., Isaacson K., Toth T., Schneyer A.L. Characterization of inhibin/activin subunit, activin receptor, and follistatin messenger ribonucleic acid in human and mouse oocytes: evidence for activin's paracrine signaling from granulosa cells to oocytes. Biol. Reprod 1998, 59:807-812.
    • (1998) Biol. Reprod , vol.59 , pp. 807-812
    • Sidis, Y.1    Fujiwara, T.2    Leykin, L.3    Isaacson, K.4    Toth, T.5    Schneyer, A.L.6
  • 38
    • 0031807461 scopus 로고    scopus 로고
    • Effects of recombinant activin A on in vitro culture of mouse preantral follicles
    • Smitz J., Cortvrindt R., Hu Y., Vanderstichele H. Effects of recombinant activin A on in vitro culture of mouse preantral follicles. Mol. Reprod. Dev 1998, 50:294-304.
    • (1998) Mol. Reprod. Dev , vol.50 , pp. 294-304
    • Smitz, J.1    Cortvrindt, R.2    Hu, Y.3    Vanderstichele, H.4
  • 40
    • 84861523612 scopus 로고    scopus 로고
    • Activin B is produced early in antral follicular development and suppresses thecal androgen production
    • Young J.M., Henderson S., Souza C., Ludlow H., Groome N., McNeilly A.S. Activin B is produced early in antral follicular development and suppresses thecal androgen production. Reproduction 2012, 143:637-650.
    • (2012) Reproduction , vol.143 , pp. 637-650
    • Young, J.M.1    Henderson, S.2    Souza, C.3    Ludlow, H.4    Groome, N.5    McNeilly, A.S.6
  • 41
    • 11144300244 scopus 로고    scopus 로고
    • MEKK1 transduces activin signals in keratinocytes to induce actin stress fiber formation and migration
    • Zhang L., Deng M., Parthasarathy R., Wang L., Mongan M., Molkentin J.D., et al. MEKK1 transduces activin signals in keratinocytes to induce actin stress fiber formation and migration. Mol. Cell. Biol 2005, 25:60-65.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 60-65
    • Zhang, L.1    Deng, M.2    Parthasarathy, R.3    Wang, L.4    Mongan, M.5    Molkentin, J.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.