Recombinant BMP4 and BMP7 increase activin A production by up-regulating inhibin βA subunit and furin expression in human granulosa-lutein cells

Journal of Clinical Endocrinology and Metabolism

Volumn 100, Issue 3, 2015, Pages E375-E386

  Chang, Hsun Ming ^a   Cheng, Jung Chien ^a   Klausen, Christian ^a   Leung, Peter C K ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; BONE MORPHOGENETIC PROTEIN 4; DORSOMORPHIN; FURIN; INHIBIN A; MESSENGER RNA; OSTEOGENIC PROTEIN 1; SMAD4 PROTEIN; SMALL INTERFERING RNA; ACTIVIN; BMP4 PROTEIN, HUMAN; BMP7 PROTEIN, HUMAN; FURIN PROTEIN, HUMAN; INHIBIN; INHIBIN BETA A SUBUNIT; RECOMBINANT PROTEIN;

ARTICLE; CONTROLLED STUDY; ENZYME IMMUNOASSAY; FEMALE; FURIN GENE; GENE EXPRESSION; GRANULOSA CELL; HUMAN; HUMAN CELL; INHIBIN BETAA GENE; LUTEAL CELL; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN TARGETING; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN PROCESSING;

ACTIVINS; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 7; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FURIN; HUMANS; INHIBIN-BETA SUBUNITS; LUTEAL CELLS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; RECOMBINANT PROTEINS; UP-REGULATION;

EID: 84922222110     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2014-3026     Document Type: Article

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