Acute exacerbations of chronic obstructive pulmonary disease are associated with decreased CD4+ & CD8+ T cells and increased growth & differentiation factor-15 (GDF-15) in peripheral blood

Respiratory Research

Volumn 16, Issue 1, 2015, Pages

  Freeman, Christine M ^a,c   Martinez, Carlos H ^c   Todt, Jill C ^c   Martinez, Fernando J ^c   Han, MeiLan K ^c   Thompson, Deborah L ^c   McCloskey, Lisa ^c   Curtis, Jeffrey L ^a,b,c,d  

^a VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Blood biomarkers; COPD; Exacerbation; Flow cytometry; Human; Sputum

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; CD40 ANTIGEN; CD86 ANTIGEN; GROWTH DIFFERENTIATION FACTOR 15; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 15; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; VASCULAR CELL ADHESION MOLECULE 1; GDF15 PROTEIN, HUMAN;

ADAPTIVE IMMUNITY; ADOLESCENT; ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; DENDRITIC CELL; DISEASE EXACERBATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GRANULOCYTE; HUMAN; LONGITUDINAL STUDY; MALE; MIDDLE AGED; OBSERVATIONAL STUDY; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; YOUNG ADULT; ACUTE DISEASE; AGED; BLOOD; DISEASE COURSE; METABOLISM; MONONUCLEAR CELL; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SPUTUM;

ACUTE DISEASE; AGED; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; COHORT STUDIES; DISEASE PROGRESSION; FEMALE; GROWTH DIFFERENTIATION FACTOR 15; HUMANS; LEUKOCYTES, MONONUCLEAR; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SPUTUM;

EID: 84939430795     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/s12931-015-0251-1     Document Type: Article

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