Acute exacerbations of chronic obstructive pulmonary disease: Identification of biologic clusters and their biomarkers

American Journal of Respiratory and Critical Care Medicine

Volumn 184, Issue 6, 2011, Pages 662-671

  Bafadhel, Mona ^a   McKenna, Susan ^a   Terry, Sarah ^a   Mistry, Vijay ^a   Reid, Carlene ^a   Haldar, Pranabashis ^a   McCormick, Margaret ^b   Haldar, Koirobi ^a   Kebadze, Tatiana ^c   Duvoix, Annelyse ^d   Lindblad, Kerstin ^e   Patel, Hemu ^f   Rugman, Paul ^b   Dodson, Paul ^b   Jenkins, Martin ^b   Saunders, Michael ^b   Newbold, Paul ^b   Green, Ruth H ^a   Venge, Per ^e   Lomas, David A ^d   Barer, Michael R ^a   Johnston, Sebastian L ^c   Pavord, Ian D ^a   Brightling, Christopher E ^a   more..

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e UPPSALA UNIVERSITY   (Sweden)

^f UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST   (United Kingdom)

Author keywords

Airway inflammation; Chronic obstructive pulmonary disease; Exacerbations; Infection; Phenotypes

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BIOLOGICAL MARKER; CORTICOSTEROID; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 1BETA; PREDNISOLONE;

ADULT; AGED; ARTICLE; BACTERIUM CULTURE; CELL HETEROGENEITY; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ASSESSMENT; CLUSTER ANALYSIS; CONTROLLED STUDY; DIAGNOSTIC TEST; DISEASE ASSOCIATION; DISEASE EXACERBATION; EOSINOPHILIA; FEMALE; HEALTH SERVICE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; RESPIRATORY TRACT INFLAMMATION; SERUM; SPUTUM ANALYSIS;

ADULT; AGED; AGED, 80 AND OVER; BACTERIAL INFECTIONS; BIOLOGICAL MARKERS; CHEMOKINE CXCL10; CLUSTER ANALYSIS; EOSINOPHILS; FEMALE; HUMANS; INFLAMMATION; INTERLEUKIN-1BETA; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; ROC CURVE; SEVERITY OF ILLNESS INDEX; SPUTUM;

EID: 80052936263     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201104-0597OC     Document Type: Article

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