-
1
-
-
0033373623
-
A dietary intervention (high carbohydrate) during the neonatal period causes islet dysfunction in rats
-
COI: 1:CAS:528:DC%2BD3cXhs1yjtg%3D%3D
-
Aalinkeel R, Srinivasan M, Kalhan SC, Laychock SG, Patel MS (1999) A dietary intervention (high carbohydrate) during the neonatal period causes islet dysfunction in rats. Am J Physiol Endocrinol Metab 277:E1061–E1069
-
(1999)
Am J Physiol Endocrinol Metab
, vol.277
, pp. 1061-1069
-
-
Aalinkeel, R.1
Srinivasan, M.2
Kalhan, S.C.3
Laychock, S.G.4
Patel, M.S.5
-
2
-
-
0027994097
-
Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels
-
COI: 1:CAS:528:DyaK2cXlsV2nur4%3D
-
Becker TC, BeltrandelRio H, Noel RJ, Johnson JH, Newgard CB (1994) Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels. J Biol Chem 269:21234–21238
-
(1994)
J Biol Chem
, vol.269
, pp. 21234-21238
-
-
Becker, T.C.1
BeltrandelRio, H.2
Noel, R.J.3
Johnson, J.H.4
Newgard, C.B.5
-
3
-
-
84884860377
-
Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes
-
Birkenfeld AL, Shulman GI (2014) Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes. Hepatology 59:713–723
-
(2014)
Hepatology
, vol.59
, pp. 713-723
-
-
Birkenfeld, A.L.1
Shulman, G.I.2
-
4
-
-
0032030866
-
Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation
-
COI: 1:CAS:528:DyaK1cXhs1yqsLY%3D
-
Bollheimer LC, Skelly RH, Chester MW, McGarry JD, Rhodes CJ (1998) Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation. J Clin Invest 101:1094
-
(1998)
J Clin Invest
, vol.101
, pp. 1094
-
-
Bollheimer, L.C.1
Skelly, R.H.2
Chester, M.W.3
McGarry, J.D.4
Rhodes, C.J.5
-
5
-
-
77951891625
-
Flavanols and anthocyanins in cardiovascular health: a review of current evidence
-
de Pascual-Teresa S, Moreno DA, García-Viguera C (2010) Flavanols and anthocyanins in cardiovascular health: a review of current evidence. Int J Mol Sci 11:1679–1703
-
(2010)
Int J Mol Sci
, vol.11
, pp. 1679-1703
-
-
de Pascual-Teresa, S.1
Moreno, D.A.2
García-Viguera, C.3
-
6
-
-
33947373424
-
Glucotoxicity inhibits late steps of insulin exocytosis
-
COI: 1:CAS:528:DC%2BD2sXjvVOhtro%3D
-
Dubois M, Vacher P, Roger B, Huyghe D, Vandewalle B, Kerr-Conte J, Pattou F, Moustaïd-Moussa N, Lang J (2007) Glucotoxicity inhibits late steps of insulin exocytosis. Endocrinology 148:1605–1614
-
(2007)
Endocrinology
, vol.148
, pp. 1605-1614
-
-
Dubois, M.1
Vacher, P.2
Roger, B.3
Huyghe, D.4
Vandewalle, B.5
Kerr-Conte, J.6
Pattou, F.7
Moustaïd-Moussa, N.8
Lang, J.9
-
7
-
-
0035042679
-
β-cell mass dynamics in Zucker diabetic fatty rats rosiglitazone prevents the rise in net cell death
-
COI: 1:CAS:528:DC%2BD3MXkvFSgur0%3D
-
Finegood DT, McArthur MD, Kojwang D, Thomas MJ, Topp BG, Leonard T, Buckingham RE (2001) β-cell mass dynamics in Zucker diabetic fatty rats rosiglitazone prevents the rise in net cell death. Diabetes 50:1021–1029
-
(2001)
Diabetes
, vol.50
, pp. 1021-1029
-
-
Finegood, D.T.1
McArthur, M.D.2
Kojwang, D.3
Thomas, M.J.4
Topp, B.G.5
Leonard, T.6
Buckingham, R.E.7
-
8
-
-
0036287834
-
Comparison of the secretory properties of four insulin-secreting cell lines
-
COI: 1:CAS:528:DC%2BD38XlslSitrg%3D
-
Hamid M, McCluskey J, McClenaghan N, Flatt P (2002) Comparison of the secretory properties of four insulin-secreting cell lines. Endocr Res 28:35–47
-
(2002)
Endocr Res
, vol.28
, pp. 35-47
-
-
Hamid, M.1
McCluskey, J.2
McClenaghan, N.3
Flatt, P.4
-
9
-
-
0029920943
-
Defective fatty acid-mediated-cell compensation in Zucker diabetic fatty rats
-
COI: 1:CAS:528:DyaK28XhsFehtr8%3D
-
Hirose H, Lee YH, Inman LR, Nagasawa Y, Johnson JH, Unger RH (1996) Defective fatty acid-mediated-cell compensation in Zucker diabetic fatty rats. J Biol Chem 271:5633–5637
-
(1996)
J Biol Chem
, vol.271
, pp. 5633-5637
-
-
Hirose, H.1
Lee, Y.H.2
Inman, L.R.3
Nagasawa, Y.4
Johnson, J.H.5
Unger, R.H.6
-
10
-
-
8344271936
-
Cell lines derived from pancreatic islets
-
COI: 1:CAS:528:DC%2BD2cXpslGms7o%3D
-
Hohmeier HE, Newgard CB (2004) Cell lines derived from pancreatic islets. Mol Cell Endocrinol 228:121–128
-
(2004)
Mol Cell Endocrinol
, vol.228
, pp. 121-128
-
-
Hohmeier, H.E.1
Newgard, C.B.2
-
12
-
-
11244279678
-
Insulin secretion by bioactive anthocyanins and anthocyanidins present in fruits
-
COI: 1:CAS:528:DC%2BD2cXhtVOru7jO
-
Jayaprakasam B, Vareed SK, Olson LK, Nair MG (2005) Insulin secretion by bioactive anthocyanins and anthocyanidins present in fruits. J Agric Food Chem 53:28–31
-
(2005)
J Agric Food Chem
, vol.53
, pp. 28-31
-
-
Jayaprakasam, B.1
Vareed, S.K.2
Olson, L.K.3
Nair, M.G.4
-
13
-
-
31044449046
-
Amelioration of obesity and glucose intolerance in high-fat-fed C57BL/6 mice by anthocyanins and ursolic acid in Cornelian cherry (Cornus mas)
-
COI: 1:CAS:528:DC%2BD2MXht1ynsrzF
-
Jayaprakasam B, Olson LK, Schutzki RE, Tai M-H, Nair MG (2006) Amelioration of obesity and glucose intolerance in high-fat-fed C57BL/6 mice by anthocyanins and ursolic acid in Cornelian cherry (Cornus mas). J Agric Food Chem 54:243–248
-
(2006)
J Agric Food Chem
, vol.54
, pp. 243-248
-
-
Jayaprakasam, B.1
Olson, L.K.2
Schutzki, R.E.3
Tai, M.-H.4
Nair, M.G.5
-
14
-
-
10044223312
-
Bioavailability of phenolic compounds
-
COI: 1:CAS:528:DC%2BD2cXpt1Wrs7o%3D
-
Karakaya S (2004) Bioavailability of phenolic compounds. Crit Rev Food Sci 44:453–464
-
(2004)
Crit Rev Food Sci
, vol.44
, pp. 453-464
-
-
Karakaya, S.1
-
15
-
-
70449713491
-
Problems associated with glucose toxicity: role of hyperglycemia-induced oxidative stress
-
COI: 1:CAS:528:DC%2BD1MXhtFSju77J
-
Kawahito S, Kitahata H, Oshita S (2009) Problems associated with glucose toxicity: role of hyperglycemia-induced oxidative stress. World J Gastroenterol 15:4137–4142
-
(2009)
World J Gastroenterol
, vol.15
, pp. 4137-4142
-
-
Kawahito, S.1
Kitahata, H.2
Oshita, S.3
-
16
-
-
70449133334
-
Diabetes and apoptosis: lipotoxicity
-
COI: 1:CAS:528:DC%2BD1MXhtlKjsrnJ
-
Kusminski CM, Shetty S, Orci L, Unger RH, Scherer PE (2009) Diabetes and apoptosis: lipotoxicity. Apoptosis 14:1484–1495
-
(2009)
Apoptosis
, vol.14
, pp. 1484-1495
-
-
Kusminski, C.M.1
Shetty, S.2
Orci, L.3
Unger, R.H.4
Scherer, P.E.5
-
17
-
-
77953885976
-
Bog bilberry (Vaccinium uliginosum L.) extract reduces cultured Hep-G2, Caco-2, and 3T3-L1 cell viability, affects cell cycle progression, and has variable effects on membrane permeability
-
COI: 1:CAS:528:DC%2BC3cXkvFCqt7k%3D
-
Liu J, Zhang W, Jing H, Popovich DG (2010a) Bog bilberry (Vaccinium uliginosum L.) extract reduces cultured Hep-G2, Caco-2, and 3T3-L1 cell viability, affects cell cycle progression, and has variable effects on membrane permeability. J Food Sci 75:H103–H107
-
(2010)
J Food Sci
, vol.75
, pp. 103-107
-
-
Liu, J.1
Zhang, W.2
Jing, H.3
Popovich, D.G.4
-
18
-
-
78651062672
-
Identification of anthocyanin components of wild Chinese blueberries and amelioration of light-induced retinal damage in pigmented rabbit using whole berries
-
Liu Y, Song X, Han Y, Zhou F, Zhang D, Ji B, Hu J, Lv Y, Cai S, Wei Y (2010b) Identification of anthocyanin components of wild Chinese blueberries and amelioration of light-induced retinal damage in pigmented rabbit using whole berries. J Agric Food Chem 59:356–363
-
(2010)
J Agric Food Chem
, vol.59
, pp. 356-363
-
-
Liu, Y.1
Song, X.2
Han, Y.3
Zhou, F.4
Zhang, D.5
Ji, B.6
Hu, J.7
Lv, Y.8
Cai, S.9
Wei, Y.10
-
19
-
-
81255195808
-
Inhibitory effect of blueberry polyphenolic compounds on oleic acid-induced hepatic steatosis in vitro
-
COI: 1:CAS:528:DC%2BC3MXhtlajur3N
-
Liu Y, Wang D, Zhang D, Lv Y, Wei Y, Wu W, Zhou F, Tang M, Mao T, Li M (2011) Inhibitory effect of blueberry polyphenolic compounds on oleic acid-induced hepatic steatosis in vitro. J Agric Food Chem 59:12254–12263
-
(2011)
J Agric Food Chem
, vol.59
, pp. 12254-12263
-
-
Liu, Y.1
Wang, D.2
Zhang, D.3
Lv, Y.4
Wei, Y.5
Wu, W.6
Zhou, F.7
Tang, M.8
Mao, T.9
Li, M.10
-
20
-
-
12344305124
-
Mitochondrial dysfunction and type 2 diabetes
-
COI: 1:CAS:528:DC%2BD2MXksFyhtw%3D%3D
-
Lowell BB, Shulman GI (2005) Mitochondrial dysfunction and type 2 diabetes. Science 307:384–387
-
(2005)
Science
, vol.307
, pp. 384-387
-
-
Lowell, B.B.1
Shulman, G.I.2
-
21
-
-
0036318319
-
Lipotoxicity in human pancreatic islets and the protective effect of metformin
-
COI: 1:CAS:528:DC%2BD38XhtVaqsLs%3D
-
Lupi R, Del Guerra S, Fierabracci V, Marselli L, Novelli M, Patanè G, Boggi U, Mosca F, Piro S, Del Prato S (2002) Lipotoxicity in human pancreatic islets and the protective effect of metformin. Diabetes 51:S134–S137
-
(2002)
Diabetes
, vol.51
, pp. 134-137
-
-
Lupi, R.1
Del Guerra, S.2
Fierabracci, V.3
Marselli, L.4
Novelli, M.5
Patanè, G.6
Boggi, U.7
Mosca, F.8
Piro, S.9
Del Prato, S.10
-
22
-
-
70449602358
-
The anti-diabetic effect of anthocyanins in streptozotocin-induced diabetic rats through glucose transporter 4 regulation and prevention of insulin resistance and pancreatic apoptosis
-
COI: 1:CAS:528:DC%2BD1MXhtlyqu7jM
-
Nizamutdinova IT, Jin YC, Chung JI, Shin SC, Lee SJ, Seo HG, Lee JH, Chang KC, Kim HJ (2009) The anti-diabetic effect of anthocyanins in streptozotocin-induced diabetic rats through glucose transporter 4 regulation and prevention of insulin resistance and pancreatic apoptosis. Mol Nutr Food Res 53:1419–1429
-
(2009)
Mol Nutr Food Res
, vol.53
, pp. 1419-1429
-
-
Nizamutdinova, I.T.1
Jin, Y.C.2
Chung, J.I.3
Shin, S.C.4
Lee, S.J.5
Seo, H.G.6
Lee, J.H.7
Chang, K.C.8
Kim, H.J.9
-
23
-
-
0029829250
-
Differential metabolic effects of adenovirus-mediated glucokinase and hexokinase I overexpression in rat primary hepatocytes
-
O’Doherty RM, Lehman DL, Seoane J, Gómez-Foix AM, Guinovart JJ, Newgard CB (1996) Differential metabolic effects of adenovirus-mediated glucokinase and hexokinase I overexpression in rat primary hepatocytes. J Biol Chem 271:20524–20530
-
(1996)
J Biol Chem
, vol.271
, pp. 20524-20530
-
-
O’Doherty, R.M.1
Lehman, D.L.2
Seoane, J.3
Gómez-Foix, A.M.4
Guinovart, J.J.5
Newgard, C.B.6
-
24
-
-
0030001414
-
Analysis of the signaling pathway involved in the regulation of hexokinase II gene transcription by insulin
-
COI: 1:CAS:528:DyaK28Xkt1Cjs7o%3D
-
Osawa H, Sutherland C, Robey RB, Printz RL, Granner DK (1996) Analysis of the signaling pathway involved in the regulation of hexokinase II gene transcription by insulin. J Biol Chem 271:16690–16694
-
(1996)
J Biol Chem
, vol.271
, pp. 16690-16694
-
-
Osawa, H.1
Sutherland, C.2
Robey, R.B.3
Printz, R.L.4
Granner, D.K.5
-
25
-
-
0036797785
-
Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress
-
COI: 1:CAS:528:DC%2BD38XnvFGru78%3D
-
Piro S, Anello M, Di Pietro C, Lizzio MN, Patane G, Rabuazzo AM, Vigneri R, Purrello M, Purrello F (2002) Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress. Metabolism 51:1340–1347
-
(2002)
Metabolism
, vol.51
, pp. 1340-1347
-
-
Piro, S.1
Anello, M.2
Di Pietro, C.3
Lizzio, M.N.4
Patane, G.5
Rabuazzo, A.M.6
Vigneri, R.7
Purrello, M.8
Purrello, F.9
-
26
-
-
0036153256
-
Mini review: secondary β-cell failure in type 2 diabetes—a convergence of glucotoxicity and lipotoxicity
-
COI: 1:CAS:528:DC%2BD38XosFWltg%3D%3D
-
Poitout V, Robertson RP (2002) Mini review: secondary β-cell failure in type 2 diabetes—a convergence of glucotoxicity and lipotoxicity. Endocrinology 143:339–342
-
(2002)
Endocrinology
, vol.143
, pp. 339-342
-
-
Poitout, V.1
Robertson, R.P.2
-
27
-
-
43549108142
-
Glucolipotoxicity: fuel excess and β-cell dysfunction
-
COI: 1:CAS:528:DC%2BD1cXntV2lsbk%3D
-
Poitout V, Robertson RP (2008) Glucolipotoxicity: fuel excess and β-cell dysfunction. Endocr Rev 29:351–366
-
(2008)
Endocr Rev
, vol.29
, pp. 351-366
-
-
Poitout, V.1
Robertson, R.P.2
-
28
-
-
24044513942
-
A review on the role of antioxidants in the management of diabetes and its complications
-
COI: 1:CAS:528:DC%2BD2MXpslygsrk%3D
-
Rahimi R, Nikfar S, Larijani B, Abdollahi M (2005) A review on the role of antioxidants in the management of diabetes and its complications. Biomed Pharmacother 59:365–373
-
(2005)
Biomed Pharmacother
, vol.59
, pp. 365-373
-
-
Rahimi, R.1
Nikfar, S.2
Larijani, B.3
Abdollahi, M.4
-
29
-
-
0842284799
-
β-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes
-
COI: 1:CAS:528:DC%2BD2cXhtlGqtr8%3D
-
Robertson RP, Harmon J, Tran POT, Poitout V (2004) β-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes. Diabetes 53:S119–S124
-
(2004)
Diabetes
, vol.53
, pp. 119-124
-
-
Robertson, R.P.1
Harmon, J.2
Tran, P.O.T.3
Poitout, V.4
-
30
-
-
0034207939
-
Nutrient toxicity in pancreatic β-cell dysfunction
-
COI: 1:CAS:528:DC%2BD3cXntFKqu7k%3D
-
Roche E, Maestre I, Martin F, Fuentes E, Casero J, Reig J, Soria B (2000) Nutrient toxicity in pancreatic β-cell dysfunction. J Physiol Biochem 56:119–128
-
(2000)
J Physiol Biochem
, vol.56
, pp. 119-128
-
-
Roche, E.1
Maestre, I.2
Martin, F.3
Fuentes, E.4
Casero, J.5
Reig, J.6
Soria, B.7
-
31
-
-
84857648468
-
Evaluation of the effects of anthocyanins in type 2 diabetes
-
Sancho RAS, Pastore GM (2011) Evaluation of the effects of anthocyanins in type 2 diabetes. Food Res Int 46:378–386
-
(2011)
Food Res Int
, vol.46
, pp. 378-386
-
-
Sancho, R.A.S.1
Pastore, G.M.2
-
32
-
-
0037592261
-
Dietary cyanidin 3-O-β-D-glucoside-rich purple corn color prevents obesity and ameliorates hyperglycemia in mice
-
COI: 1:CAS:528:DC%2BD3sXmsFOmurw%3D
-
Tsuda T, Horio F, Uchida K, Aoki H, Osawa T (2003) Dietary cyanidin 3-O-β-D-glucoside-rich purple corn color prevents obesity and ameliorates hyperglycemia in mice. J Nutr 133:2125–2130
-
(2003)
J Nutr
, vol.133
, pp. 2125-2130
-
-
Tsuda, T.1
Horio, F.2
Uchida, K.3
Aoki, H.4
Osawa, T.5
-
33
-
-
33644824893
-
Microarray profiling of gene expression in human adipocytes in response to anthocyanins
-
COI: 1:CAS:528:DC%2BD28Xit1ynu70%3D
-
Tsuda T, Ueno Y, Yoshikawa T, Kojo H, Osawa T (2006) Microarray profiling of gene expression in human adipocytes in response to anthocyanins. Biochem Pharmacol 71:1184–1197
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 1184-1197
-
-
Tsuda, T.1
Ueno, Y.2
Yoshikawa, T.3
Kojo, H.4
Osawa, T.5
-
34
-
-
0032986801
-
Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries
-
COI: 1:CAS:528:DyaK1MXlvFCjtg%3D%3D
-
Wang H, Nair MG, Strasburg GM, Chang YC, Booren AM, Gray JI, DeWitt DL (1999) Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries. J Nat Prod 62:294–296
-
(1999)
J Nat Prod
, vol.62
, pp. 294-296
-
-
Wang, H.1
Nair, M.G.2
Strasburg, G.M.3
Chang, Y.C.4
Booren, A.M.5
Gray, J.I.6
DeWitt, D.L.7
-
35
-
-
77955050634
-
Hypolipidemic and antioxidant effects of mulberry (Morus alba L.) fruit in hyperlipidaemia rats
-
COI: 1:CAS:528:DC%2BC3cXptlGhsbg%3D
-
Yang X, Yang L, Zheng H (2010) Hypolipidemic and antioxidant effects of mulberry (Morus alba L.) fruit in hyperlipidaemia rats. Food Chem Toxicol 48:2374–2379
-
(2010)
Food Chem Toxicol
, vol.48
, pp. 2374-2379
-
-
Yang, X.1
Yang, L.2
Zheng, H.3
-
36
-
-
23744447643
-
Mechanisms of oleic acid deterioration in insulin secretion: role in the pathogenesis of type 2 diabetes
-
COI: 1:CAS:528:DC%2BD2MXns1Wlu7g%3D
-
Zhang Y, Xiao M, Niu G, Tan H (2005) Mechanisms of oleic acid deterioration in insulin secretion: role in the pathogenesis of type 2 diabetes. Life Sci 77:2071–2081
-
(2005)
Life Sci
, vol.77
, pp. 2071-2081
-
-
Zhang, Y.1
Xiao, M.2
Niu, G.3
Tan, H.4
-
37
-
-
78751529598
-
Anthocyanins from Chinese bayberry extract protect β cells from oxidative stress-mediated injury via HO-1 upregulation
-
Zhang B, Kang M, Xie Q, Xu B, Sun C, Chen K, Wu Y (2010) Anthocyanins from Chinese bayberry extract protect β cells from oxidative stress-mediated injury via HO-1 upregulation. J Agric Food Chem 59:537–545
-
(2010)
J Agric Food Chem
, vol.59
, pp. 537-545
-
-
Zhang, B.1
Kang, M.2
Xie, Q.3
Xu, B.4
Sun, C.5
Chen, K.6
Wu, Y.7
-
38
-
-
80052933853
-
Comparative study on antioxidant capacity of flavonoids and their inhibitory effects on oleic acid-induced hepatic steatosis in vitro
-
COI: 1:CAS:528:DC%2BC3MXhtV2rtb%2FK
-
Zhang D, Xie L, Jia G, Cai S, Ji B, Liu Y, Wu W, Zhou F, Wang A, Chu L, Wei Y, Liu J, Gao F (2011) Comparative study on antioxidant capacity of flavonoids and their inhibitory effects on oleic acid-induced hepatic steatosis in vitro. Eur J Med Chem 46:4548–4558
-
(2011)
Eur J Med Chem
, vol.46
, pp. 4548-4558
-
-
Zhang, D.1
Xie, L.2
Jia, G.3
Cai, S.4
Ji, B.5
Liu, Y.6
Wu, W.7
Zhou, F.8
Wang, A.9
Chu, L.10
Wei, Y.11
Liu, J.12
Gao, F.13
-
39
-
-
0028268936
-
Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle
-
COI: 1:CAS:528:DyaK2cXktVWntb4%3D
-
Zhou YP, Grill VE (1994) Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle. J Clin Invest 93:870–876
-
(1994)
J Clin Invest
, vol.93
, pp. 870-876
-
-
Zhou, Y.P.1
Grill, V.E.2
|