-
1
-
-
0032568920
-
Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis
-
Antinozzi P.A., Segall L., Prentki M., McGarry J.D., Newgard C.B. Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis. J. Biol. Chem. 273:1998;16146-16154
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16146-16154
-
-
Antinozzi, P.A.1
Segall, L.2
Prentki, M.3
McGarry, J.D.4
Newgard, C.B.5
-
2
-
-
0026550830
-
Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines
-
Asfari M., Janjic D., Meda P., Li G., Halban P.A., Wollheim C.B. Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology. 130:1992;167-178
-
(1992)
Endocrinology
, vol.130
, pp. 167-178
-
-
Asfari, M.1
Janjic, D.2
Meda, P.3
Li, G.4
Halban, P.A.5
Wollheim, C.B.6
-
3
-
-
0022878020
-
Insulin secretory responses of a clonal cell line of simian virus 40-transformed B cells
-
Ashcroft S.J., Hammonds P., Harrison D.E. Insulin secretory responses of a clonal cell line of simian virus 40-transformed B cells. Diabetologia. 29:1986;727-733
-
(1986)
Diabetologia
, vol.29
, pp. 727-733
-
-
Ashcroft, S.J.1
Hammonds, P.2
Harrison, D.E.3
-
4
-
-
0019131883
-
Glucagon secreting clones of rat islet cell tumor
-
Bhathena S.J., Voyles N.R., Oie H.K., Smith S.S., Gazdar A.F., Recant L. Glucagon secreting clones of rat islet cell tumor. Horm. Metab. Res. 12:1980;632-633
-
(1980)
Horm. Metab. Res.
, vol.12
, pp. 632-633
-
-
Bhathena, S.J.1
Voyles, N.R.2
Oie, H.K.3
Smith, S.S.4
Gazdar, A.F.5
Recant, L.6
-
5
-
-
0020070165
-
Insulin, glucagon, and somatostatin receptors on cultured cells and clones from rat islet cell tumor
-
Bhathena S.J., Oie H.K., Gazdar A.F., Voyles N.R., Wilkins S.D., Recant L. Insulin, glucagon, and somatostatin receptors on cultured cells and clones from rat islet cell tumor. Diabetes. 31:1982;521-531
-
(1982)
Diabetes
, vol.31
, pp. 521-531
-
-
Bhathena, S.J.1
Oie, H.K.2
Gazdar, A.F.3
Voyles, N.R.4
Wilkins, S.D.5
Recant, L.6
-
6
-
-
0041994085
-
The anatomy, organization and ultrastructure of the islets of Langerhans
-
Pickup, J., Williams, G. (Eds.), Blackwell, Oxford, 1997
-
Bishop, A.E., Polak, J.M., 1997. The anatomy, organization and ultrastructure of the islets of Langerhans. In: Pickup, J., Williams, G. (Eds.), Textbook of Diabetes, Blackwell, Oxford, 1997, pp. 6.1-6.16.
-
(1997)
Textbook of Diabetes
, pp. 61-616
-
-
Bishop, A.E.1
Polak, J.M.2
-
7
-
-
0022517433
-
Calcium dependency and free calcium concentrations during insulin secretion in a hamster beta cell line
-
Boyd A.E., Hill R.S., Oberwetter J.M., Berg M. Calcium dependency and free calcium concentrations during insulin secretion in a hamster beta cell line. J. Clin. Invest. 77:1986;774-781
-
(1986)
J. Clin. Invest.
, vol.77
, pp. 774-781
-
-
Boyd, A.E.1
Hill, R.S.2
Oberwetter, J.M.3
Berg, M.4
-
8
-
-
0001205038
-
A transplantable insulinoma in the rat
-
Chick W.L., Warren S., Chute R.N., Like A.A., Lauris V., Kitchen K.C. A transplantable insulinoma in the rat. Proc. Natl. Acad. Sci. U.S.A. 74:1977;628-632
-
(1977)
Proc. Natl. Acad. Sci. U.S.A.
, vol.74
, pp. 628-632
-
-
Chick, W.L.1
Warren, S.2
Chute, R.N.3
Like, A.A.4
Lauris, V.5
Kitchen, K.C.6
-
9
-
-
0025612085
-
Modulation of glucose-induced insulin secretion from a rat clonal beta-cell line
-
Clark S.A., Burnham B.L., Chick W.L. Modulation of glucose-induced insulin secretion from a rat clonal beta-cell line. Endocrinology. 127:1990;2779-2788
-
(1990)
Endocrinology
, vol.127
, pp. 2779-2788
-
-
Clark, S.A.1
Burnham, B.L.2
Chick, W.L.3
-
10
-
-
0030948732
-
Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression
-
Clark S.A., Quaade C., Constandy H., Hansen P., Halban P., Ferber S., Newgard C.B., Normington K. Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression. Diabetes. 46:1997;958-967
-
(1997)
Diabetes
, vol.46
, pp. 958-967
-
-
Clark, S.A.1
Quaade, C.2
Constandy, H.3
Hansen, P.4
Halban, P.5
Ferber, S.6
Newgard, C.B.7
Normington, K.8
-
11
-
-
0025374590
-
Regulation of insulin secretion from β-cell lines derived from transgenic mice insulinomas resembles that of normal β-cells
-
D'Ambra R., Surana M., Efrat S., Starr R.G., Fleischer N. Regulation of insulin secretion from β-cell lines derived from transgenic mice insulinomas resembles that of normal β-cells. Endocrinology. 126:1990;2815-2822
-
(1990)
Endocrinology
, vol.126
, pp. 2815-2822
-
-
D'Ambra, R.1
Surana, M.2
Efrat, S.3
Starr, R.G.4
Fleischer, N.5
-
13
-
-
0023785113
-
Proglucagon gene expression and posttranslational processing in a hamster islet cell line
-
Drucker D.J., Philippe J., Mojsov S. Proglucagon gene expression and posttranslational processing in a hamster islet cell line. Endocrinology. 123:1988;1861-1867
-
(1988)
Endocrinology
, vol.123
, pp. 1861-1867
-
-
Drucker, D.J.1
Philippe, J.2
Mojsov, S.3
-
14
-
-
0000181874
-
Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene
-
Efrat S., Linde S., Kofod H., Spector D., Delannoy M., Grant S., Hanahan D., Baekkeskov S. Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene. Proc. Natl. Acad. Sci. U.S.A. 85:1988a;9037-9041
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 9037-9041
-
-
Efrat, S.1
Linde, S.2
Kofod, H.3
Spector, D.4
Delannoy, M.5
Grant, S.6
Hanahan, D.7
Baekkeskov, S.8
-
15
-
-
0024074541
-
Glucagon gene regulatory region directs oncoprotein expression to neurons and pancreatic α cells
-
Efrat S., Teitelman G., Anwar M., Ruggiero D., Hanahan D. Glucagon gene regulatory region directs oncoprotein expression to neurons and pancreatic α cells. Neuron. 1:1988;605-613
-
(1988)
Neuron
, vol.1
, pp. 605-613
-
-
Efrat, S.1
Teitelman, G.2
Anwar, M.3
Ruggiero, D.4
Hanahan, D.5
-
16
-
-
0027233478
-
Murine insulinoma cell line with normal glucose-regulated insulin secretion
-
Efrat S., Leiser M., Surana M., Tal M., Fusco-Demane D., Fleischer N. Murine insulinoma cell line with normal glucose-regulated insulin secretion. Diabetes. 42:1993;901-907
-
(1993)
Diabetes
, vol.42
, pp. 901-907
-
-
Efrat, S.1
Leiser, M.2
Surana, M.3
Tal, M.4
Fusco-Demane, D.5
Fleischer, N.6
-
17
-
-
0028938747
-
Conditional transformation of a pancreatic beta-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene
-
Efrat S., Fusco-DeMane D., Lemberg H., al Emran O., Wang X. Conditional transformation of a pancreatic beta-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene. Proc. Natl. Acad. Sci. U.S.A. 92:1995;3576-3580
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 3576-3580
-
-
Efrat, S.1
Fusco-Demane, D.2
Lemberg, H.3
Al Emran, O.4
Wang, X.5
-
18
-
-
0032773593
-
Genetically engineered pancreatic beta-cell lines for therapy of diabetes
-
Efrat S. Genetically engineered pancreatic beta-cell lines for therapy of diabetes. Ann. NY Acad. Sci. 18:1998;286-293
-
(1998)
Ann. NY Acad. Sci.
, vol.18
, pp. 286-293
-
-
Efrat, S.1
-
19
-
-
0028286784
-
GLUT-2 gene transfer into insulinoma cells confers both low and high affinity glucose-stimulated insulin release. Relationship to glucokinase activity
-
Ferber S., BeltrandelRio H., Johnson J.H., Noel R.J., Cassidy L.E., Clark S., Becker T.C., Hughes S.D., Newgard C.B. GLUT-2 gene transfer into insulinoma cells confers both low and high affinity glucose-stimulated insulin release. Relationship to glucokinase activity. J. Biol. Chem. 269:1994;11523-11529
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 11523-11529
-
-
Ferber, S.1
Beltrandelrio, H.2
Johnson, J.H.3
Noel, R.J.4
Cassidy, L.E.5
Clark, S.6
Becker, T.C.7
Hughes, S.D.8
Newgard, C.B.9
-
20
-
-
0031659962
-
Functional analysis of a conditionally transformed pancreatic beta-cell line
-
Fleischer N., Chen C., Surana M., Leiser M., Rossetti L., Pralong W., Efrat S. Functional analysis of a conditionally transformed pancreatic beta-cell line. Diabetes. 47:1998;1419-1425
-
(1998)
Diabetes
, vol.47
, pp. 1419-1425
-
-
Fleischer, N.1
Chen, C.2
Surana, M.3
Leiser, M.4
Rossetti, L.5
Pralong, W.6
Efrat, S.7
-
21
-
-
0009611219
-
Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor
-
Gazdar A.F., Chick W.L., Oie H.K., Sims H.L., King D.L., Weir G.C., Lauris V. Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor. Proc. Natl. Acad. Sci. U.S.A. 77:1980;3519-3523
-
(1980)
Proc. Natl. Acad. Sci. U.S.A.
, vol.77
, pp. 3519-3523
-
-
Gazdar, A.F.1
Chick, W.L.2
Oie, H.K.3
Sims, H.L.4
King, D.L.5
Weir, G.C.6
Lauris, V.7
-
23
-
-
0024817825
-
Functional pancreatic beta-cell line from SV40 T-antigen transgenic mouse
-
Gilligan A., Jewett L., Simon D., Damjanov I., Matschinsky F.M., Weik H., Pinkert C., Knowles B.B. Functional pancreatic beta-cell line from SV40 T-antigen transgenic mouse. Diabetes. 38:1989;1056-1062
-
(1989)
Diabetes
, vol.38
, pp. 1056-1062
-
-
Gilligan, A.1
Jewett, L.2
Simon, D.3
Damjanov, I.4
Matschinsky, F.M.5
Weik, H.6
Pinkert, C.7
Knowles, B.B.8
-
24
-
-
0025269469
-
Comparison of cytokine effects on mouse pancreatic α-cell and β-cell lines
-
Hamaguchi K., Leiter E.H. Comparison of cytokine effects on mouse pancreatic α-cell and β-cell lines. Diabetes. 39:1990;415-425
-
(1990)
Diabetes
, vol.39
, pp. 415-425
-
-
Hamaguchi, K.1
Leiter, E.H.2
-
25
-
-
0025878776
-
NIT-1, a pancreatic beta-cell line established from a transgenic NOD/Lt mouse
-
Hamaguchi K., Gaskins H.R., Leiter E.H. NIT-1, a pancreatic beta-cell line established from a transgenic NOD/Lt mouse. Diabetes. 40:1991;842-849
-
(1991)
Diabetes
, vol.40
, pp. 842-849
-
-
Hamaguchi, K.1
Gaskins, H.R.2
Leiter, E.H.3
-
26
-
-
0021888904
-
Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes
-
Hanahan D. Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. Nature. 315:1985;115-122
-
(1985)
Nature
, vol.315
, pp. 115-122
-
-
Hanahan, D.1
-
27
-
-
0031831420
-
Reconstitution of glucotoxic HIT-T15 cells with somatostatin transcription factor-1 partially restores insulin promoter activity
-
Harmon J.S., Tanaka Y., Olson L.K., Robertson R.P. Reconstitution of glucotoxic HIT-T15 cells with somatostatin transcription factor-1 partially restores insulin promoter activity. Diabetes. 47:1998;900-904
-
(1998)
Diabetes
, vol.47
, pp. 900-904
-
-
Harmon, J.S.1
Tanaka, Y.2
Olson, L.K.3
Robertson, R.P.4
-
28
-
-
0030916753
-
Regulation of insulin secretion from novel engineered insulinoma cell lines
-
Hohmeier H.E., BeltrandelRio H., Clark S.A., Henkel-Rieger R., Normington K., Newgard C.B. Regulation of insulin secretion from novel engineered insulinoma cell lines. Diabetes. 46:1997;968-977
-
(1997)
Diabetes
, vol.46
, pp. 968-977
-
-
Hohmeier, H.E.1
Beltrandelrio, H.2
Clark, S.A.3
Henkel-Rieger, R.4
Normington, K.5
Newgard, C.B.6
-
30
-
-
0347511005
-
Inflammatory mechanisms in diabetes: Lessons from the beta-cell
-
Hohmeier H.E., Tran V.V., Chen G., Gasa R., Newgard C.B. Inflammatory mechanisms in diabetes: lessons from the beta-cell. Int. J. Obes. Relat. Metab. Disord. 27:2003;S12-S16
-
(2003)
Int. J. Obes. Relat. Metab. Disord.
, vol.27
-
-
Hohmeier, H.E.1
Tran, V.V.2
Chen, G.3
Gasa, R.4
Newgard, C.B.5
-
31
-
-
0027360242
-
Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets
-
Ishihara H., Asano T., Tsukuda K., Katagiri H., Inukai K., Anai M., Kikuchi M., Yazaki Y., Miyazaki J.I., Oka Y. Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets. Diabetologia. 36:1993;1139-1145
-
(1993)
Diabetologia
, vol.36
, pp. 1139-1145
-
-
Ishihara, H.1
Asano, T.2
Tsukuda, K.3
Katagiri, H.4
Inukai, K.5
Anai, M.6
Kikuchi, M.7
Yazaki, Y.8
Miyazaki, J.I.9
Oka, Y.10
-
32
-
-
8344231685
-
A preliminary report concerning tumors observed in Syrian hamsters
-
Kirkman H.A. A preliminary report concerning tumors observed in Syrian hamsters. Stanford Med. Bull. 20:1962;163
-
(1962)
Stanford Med. Bull.
, vol.20
, pp. 163
-
-
Kirkman, H.A.1
-
33
-
-
0028577616
-
Clonal insulinoma cell line that stably maintains correct glucose responsiveness
-
Knaack D., Fiore D.M., Surana M., Leiser M., Laurance M., Fusco-DeMane D., Hegre O.D., Fleischer N., Efrat S. Clonal insulinoma cell line that stably maintains correct glucose responsiveness. Diabetes. 43:1994;1413-1417
-
(1994)
Diabetes
, vol.43
, pp. 1413-1417
-
-
Knaack, D.1
Fiore, D.M.2
Surana, M.3
Leiser, M.4
Laurance, M.5
Fusco-Demane, D.6
Hegre, O.D.7
Fleischer, N.8
Efrat, S.9
-
34
-
-
0036319371
-
Pancreatic beta-cell growth and survival-a role in obesity-linked type 2 diabetes?
-
Lingohr M.K., Buettner R., Rhodes C.J. Pancreatic beta-cell growth and survival-a role in obesity-linked type 2 diabetes? Trends Mol. Med. 8:2002;375-384
-
(2002)
Trends Mol. Med.
, vol.8
, pp. 375-384
-
-
Lingohr, M.K.1
Buettner, R.2
Rhodes, C.J.3
-
35
-
-
0037022527
-
13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS)
-
Lu D., Mulder H., Zhao P., Burgess S.C., Jensen M.V., Kamzolova S., Newgard C.B., Sherry A.D. 13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS). Proc. Natl. Acad. Sci. U.S.A. 99:2002;2708-2713
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 2708-2713
-
-
Lu, D.1
Mulder, H.2
Zhao, P.3
Burgess, S.C.4
Jensen, M.V.5
Kamzolova, S.6
Newgard, C.B.7
Sherry, A.D.8
-
36
-
-
0030858390
-
Impaired expression of transcription factor IUF1 in a pancreatic beta-cell line derived from a patient with persistent hyperinsulinaemic hypoglycaemia of infancy (nesidioblastosis)
-
Macfarlane W.M., Cragg H., Docherty H.M., Read M.L., James R.F., Aynsley-Green A., Docherty K. Impaired expression of transcription factor IUF1 in a pancreatic beta-cell line derived from a patient with persistent hyperinsulinaemic hypoglycaemia of infancy (nesidioblastosis). FEBS Lett. 413:1997;304-308
-
(1997)
FEBS Lett.
, vol.413
, pp. 304-308
-
-
MacFarlane, W.M.1
Cragg, H.2
Docherty, H.M.3
Read, M.L.4
James, R.F.5
Aynsley-Green, A.6
Docherty, K.7
-
37
-
-
0033607678
-
Engineering a glucose-responsive human insulin-secreting cell line from islets of Langerhans isolated from a patient with persistent hyperinsulinemic hypoglycemia of infancy
-
MacFarlane W.M., Chapman J.C., Shepherd R.M., Hashmi M.N., Kamimura N., Cosgrove K.E., O'Brien R.E., Barnes P.D., Hart A.W., Docherty H.M., Lindley K.J., Aynsley-Green A., James R.F., Docherty K., Dunne M.J. Engineering a glucose-responsive human insulin-secreting cell line from islets of Langerhans isolated from a patient with persistent hyperinsulinemic hypoglycemia of infancy. J. Biol. Chem. 274:1999;34059-34066
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34059-34066
-
-
MacFarlane, W.M.1
Chapman, J.C.2
Shepherd, R.M.3
Hashmi, M.N.4
Kamimura, N.5
Cosgrove, K.E.6
O'Brien, R.E.7
Barnes, P.D.8
Hart, A.W.9
Docherty, H.M.10
Lindley, K.J.11
Aynsley-Green, A.12
James, R.F.13
Docherty, K.14
Dunne, M.J.15
-
38
-
-
0022467419
-
Acetylcholine stimulates glucose metabolism by pancreatic islets
-
Meglasson M.D., Najafi H., Matschinsky F.M. Acetylcholine stimulates glucose metabolism by pancreatic islets. Life Sci. 39:1986;1745-1750
-
(1986)
Life Sci.
, vol.39
, pp. 1745-1750
-
-
Meglasson, M.D.1
Najafi, H.2
Matschinsky, F.M.3
-
39
-
-
0023597750
-
Fuel-stimulated insulin secretion by clonal hamster beta-cell line HIT T-15
-
Meglasson M.D., Manning C.D., Najafi H., Matschinsky F.M. Fuel-stimulated insulin secretion by clonal hamster beta-cell line HIT T-15. Diabetes. 36:1987;477-484
-
(1987)
Diabetes
, vol.36
, pp. 477-484
-
-
Meglasson, M.D.1
Manning, C.D.2
Najafi, H.3
Matschinsky, F.M.4
-
40
-
-
0025281303
-
Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: Special reference to expression of glucose transporter isoforms
-
Miyazaki J., Araki K., Yamato E., Ikegami H., Asano T., Shibasaki Y., Oka Y., Yamamura K. Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms. Endocrinology. 127:1990;126-132
-
(1990)
Endocrinology
, vol.127
, pp. 126-132
-
-
Miyazaki, J.1
Araki, K.2
Yamato, E.3
Ikegami, H.4
Asano, T.5
Shibasaki, Y.6
Oka, Y.7
Yamamura, K.8
-
41
-
-
0029071517
-
Metabolic coupling factors in pancreatic beta-cell signal transduction
-
Newgard C.B., McGarry J.D. Metabolic coupling factors in pancreatic beta-cell signal transduction. Ann. Rev. Biochem. 64:1995;689-719
-
(1995)
Ann. Rev. Biochem.
, vol.64
, pp. 689-719
-
-
Newgard, C.B.1
McGarry, J.D.2
-
42
-
-
0030871944
-
Engineered cell lines for insulin replacement in diabetes: Current status and future prospects
-
Newgard C.B., Clark S., BeltrandelRio H., Hohmeier H.E., Quaade C., Normington K. Engineered cell lines for insulin replacement in diabetes: current status and future prospects. Diabetologia. 40(Suppl. 2):1997;S42-S47
-
(1997)
Diabetologia
, vol.40
, Issue.SUPPL. 2
-
-
Newgard, C.B.1
Clark, S.2
Beltrandelrio, H.3
Hohmeier, H.E.4
Quaade, C.5
Normington, K.6
-
43
-
-
0036830460
-
While tinkering with the beta-cell ... metabolic regulatory mechanisms and new therapeutic strategies: American Diabetes Association Lilly Lecture, 2001
-
Newgard C.B. While tinkering with the beta-cell... metabolic regulatory mechanisms and new therapeutic strategies: American Diabetes Association Lilly Lecture, 2001. Diabetes. 51:2002;3141-3150
-
(2002)
Diabetes
, vol.51
, pp. 3141-3150
-
-
Newgard, C.B.1
-
44
-
-
0029662109
-
The βhC-9 pancreatic β-cell line preserves the characteristics of progenitor mouse islets
-
Noda M., Komatsu M., Sharp W.G. The βHC-9 pancreatic β-cell line preserves the characteristics of progenitor mouse islets. Diabetes. 45:1996;1766-1773
-
(1996)
Diabetes
, vol.45
, pp. 1766-1773
-
-
Noda, M.1
Komatsu, M.2
Sharp, W.G.3
-
45
-
-
0030753653
-
Engineering of glycerol-stimulated insulin secretion in islet beta cells. Differential metabolic fates of glucose and glycerol provide insight into mechanisms of stimulus-secretion coupling
-
Noel R.J., Antinozzi P.A., McGarry J.D., Newgard C.B. Engineering of glycerol-stimulated insulin secretion in islet beta cells. Differential metabolic fates of glucose and glycerol provide insight into mechanisms of stimulus-secretion coupling. J. Biol. Chem. 272:1997;18621-18627
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18621-18627
-
-
Noel, R.J.1
Antinozzi, P.A.2
McGarry, J.D.3
Newgard, C.B.4
-
46
-
-
0027237191
-
Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein
-
Olson L.K., Redmon J.B., Towle H.C., Robertson R.P. Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein. J. Clin. Invest. 92:1993;514-519
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 514-519
-
-
Olson, L.K.1
Redmon, J.B.2
Towle, H.C.3
Robertson, R.P.4
-
47
-
-
0032230172
-
Glucose rapidly and reversibly decreases INS-1 cell insulin gene transcription via decrements in STF-1 and C1 activator transcription factor activity
-
Olson L.K., Qian J., Poitout V. Glucose rapidly and reversibly decreases INS-1 cell insulin gene transcription via decrements in STF-1 and C1 activator transcription factor activity. Mol. Endocrinol. 12:1998;207-219
-
(1998)
Mol. Endocrinol.
, vol.12
, pp. 207-219
-
-
Olson, L.K.1
Qian, J.2
Poitout, V.3
-
48
-
-
0023005768
-
Proglucagon processing in a rat islet cell line resembles phenotype of intestine rather than pancreas
-
Philippe J., Drucker D.J., Mojsov S., Habener J.F. Proglucagon processing in a rat islet cell line resembles phenotype of intestine rather than pancreas. Endocrinology. 119:1986;2833-2839
-
(1986)
Endocrinology
, vol.119
, pp. 2833-2839
-
-
Philippe, J.1
Drucker, D.J.2
Mojsov, S.3
Habener, J.F.4
-
49
-
-
0023155156
-
Multipotential phenotypic expression of genes encoding peptide hormones in rat insulinoma cell lines
-
Philippe J., Chick W.L., Habener J.F. Multipotential phenotypic expression of genes encoding peptide hormones in rat insulinoma cell lines. J. Clin. Invest. 79:1987;351-358
-
(1987)
J. Clin. Invest.
, vol.79
, pp. 351-358
-
-
Philippe, J.1
Chick, W.L.2
Habener, J.F.3
-
50
-
-
0028926254
-
Morphological and functional characterization of beta TC-6 cells-an insulin-secreting cell line derived from transgenic mice
-
Poitout V., Stout L.E., Armstrong M.B., Walseth T.F., Sorenson R.L., Robertson R.P. Morphological and functional characterization of beta TC-6 cells-an insulin-secreting cell line derived from transgenic mice. Diabetes. 44:1995;306-313
-
(1995)
Diabetes
, vol.44
, pp. 306-313
-
-
Poitout, V.1
Stout, L.E.2
Armstrong, M.B.3
Walseth, T.F.4
Sorenson, R.L.5
Robertson, R.P.6
-
51
-
-
0029664752
-
Chronic exposure of betaTC-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator
-
Poitout V., Olson L.K., Robertson R.P. Chronic exposure of betaTC-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator. J. Clin. Invest. 97:1996;1041-1046
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 1041-1046
-
-
Poitout, V.1
Olson, L.K.2
Robertson, R.P.3
-
52
-
-
0025349639
-
Proglucagon processing similar to normal islets in pancreatic α-like cell line derived from transgenic mouse tumor
-
Powers A.C., Efrat S., Mojsov S., Spector D., Habener J.F., Hanahan D. Proglucagon processing similar to normal islets in pancreatic α-like cell line derived from transgenic mouse tumor. Diabetes. 39:1990;406-414
-
(1990)
Diabetes
, vol.39
, pp. 406-414
-
-
Powers, A.C.1
Efrat, S.2
Mojsov, S.3
Spector, D.4
Habener, J.F.5
Hanahan, D.6
-
53
-
-
0020639154
-
Regulation of immunoreactive-insulin release from a rat cell line (RINm5F)
-
Praz G.A., Halban P.A., Wollheim C.B., Blondel B., Strauss A.J., Renold A.E. Regulation of immunoreactive-insulin release from a rat cell line (RINm5F). Biochem. J. 210:1983;345-352
-
(1983)
Biochem. J.
, vol.210
, pp. 345-352
-
-
Praz, G.A.1
Halban, P.A.2
Wollheim, C.B.3
Blondel, B.4
Strauss, A.J.5
Renold, A.E.6
-
54
-
-
0027299925
-
Pancreatic beta cells cultured from individual preneoplastic foci in a multistage tumorigenesis pathway: A potentially general technique for isolating physiologically representative cell lines
-
Radvanyi F., Christgau S., Baekkeskov S., Jolicoeur C., Hanahan D. Pancreatic beta cells cultured from individual preneoplastic foci in a multistage tumorigenesis pathway: a potentially general technique for isolating physiologically representative cell lines. Mol. Cell Biol. 13:1993;4223-4232
-
(1993)
Mol. Cell Biol.
, vol.13
, pp. 4223-4232
-
-
Radvanyi, F.1
Christgau, S.2
Baekkeskov, S.3
Jolicoeur, C.4
Hanahan, D.5
-
55
-
-
0026757632
-
Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations
-
Robertson R.P., Zhang H.J., Pyzdrowski K.L., Walseth T.F. Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations. J. Clin. Invest. 90:1992;320-325
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 320-325
-
-
Robertson, R.P.1
Zhang, H.J.2
Pyzdrowski, K.L.3
Walseth, T.F.4
-
56
-
-
0027157879
-
Relation between glucose-stimulated insulin secretion and intracellular calcium accumulation studied with a superfusion system of a glucose-responsive pancreatic β-cell line MIN-6
-
Sakurada M., Kanatsuka A., Saitoh T., Makino H., Yamamura K., Miyazawa J.I., Kikuchi M., Yoshida S. Relation between glucose-stimulated insulin secretion and intracellular calcium accumulation studied with a superfusion system of a glucose-responsive pancreatic β-cell line MIN-6. Endocinology. 132:1993;2659-2665
-
(1993)
Endocinology
, vol.132
, pp. 2659-2665
-
-
Sakurada, M.1
Kanatsuka, A.2
Saitoh, T.3
Makino, H.4
Yamamura, K.5
Miyazawa, J.I.6
Kikuchi, M.7
Yoshida, S.8
-
57
-
-
0001481271
-
Insulin synthesis in a clonal cell line of simian virus 40-transformed hamster pancreatic beta cells
-
Santerre R.F., Cook R.A., Crisel R.M., Sharp J.D., Schmidt R.J., Williams D.C., Wilson C.P. Insulin synthesis in a clonal cell line of simian virus 40-transformed hamster pancreatic beta cells. Proc. Natl. Acad. Sci. U.S.A. 78:1981;4339-4343
-
(1981)
Proc. Natl. Acad. Sci. U.S.A.
, vol.78
, pp. 4339-4343
-
-
Santerre, R.F.1
Cook, R.A.2
Crisel, R.M.3
Sharp, J.D.4
Schmidt, R.J.5
Williams, D.C.6
Wilson, C.P.7
-
58
-
-
0034721255
-
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
-
Shapiro A.M., Lakey J.R., Ryan E.A., Korbutt G.S., Toth E., Warnock G.L., Kneteman N.M., Rajotte R.V. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N. Engl. J. Med. 343:2000;230-238
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 230-238
-
-
Shapiro, A.M.1
Lakey, J.R.2
Ryan, E.A.3
Korbutt, G.S.4
Toth, E.5
Warnock, G.L.6
Kneteman, N.M.7
Rajotte, R.V.8
-
59
-
-
0023940073
-
Characteristics of glucokinase of the Kirkman insulinoma
-
Shimizu T., Matchinsky F.M. Characteristics of glucokinase of the Kirkman insulinoma. Metabolism. 37:1988;631-634
-
(1988)
Metabolism
, vol.37
, pp. 631-634
-
-
Shimizu, T.1
Matchinsky, F.M.2
-
60
-
-
0025000804
-
The 64-kDa beta-cell membrane autoantigen and other target molecules of humoral autoimmunity in insulin-dependent diabetes mellitus
-
Sigurdsson E., Baekkeskov S. The 64-kDa beta-cell membrane autoantigen and other target molecules of humoral autoimmunity in insulin-dependent diabetes mellitus. Curr. Top. Microbiol. Immunol. 164:1990;143-168
-
(1990)
Curr. Top. Microbiol. Immunol.
, vol.164
, pp. 143-168
-
-
Sigurdsson, E.1
Baekkeskov, S.2
-
61
-
-
0025736375
-
Transfection with SV40 gene of human pancreatic endocrine cells
-
Soldevilla G., Buscema M., Marini V., Sutton R., James R.F.L., Bloom S.R., Robertson R.P., Mirakian R., Pujol-Borrell R., Bottazzo G.F. Transfection with SV40 gene of human pancreatic endocrine cells. J. Autoimmun. 4:1991;381-396
-
(1991)
J. Autoimmun.
, vol.4
, pp. 381-396
-
-
Soldevilla, G.1
Buscema, M.2
Marini, V.3
Sutton, R.4
James, R.F.L.5
Bloom, S.R.6
Robertson, R.P.7
Mirakian, R.8
Pujol-Borrell, R.9
Bottazzo, G.F.10
-
62
-
-
0345165634
-
Bombesin stimulates insulin secretion by a pancreatic islet cell line
-
Swope S.L., Schonbrunn A. Bombesin stimulates insulin secretion by a pancreatic islet cell line. Proc. Natl. Acad. Sci. U.S.A. 81:1984;1822-1826
-
(1984)
Proc. Natl. Acad. Sci. U.S.A.
, vol.81
, pp. 1822-1826
-
-
Swope, S.L.1
Schonbrunn, A.2
-
63
-
-
0022618344
-
Isolation of glucagons-secreting cell lines by cloning insulinoma cells
-
Takaki R., Ono J., Nakamura M., Yokogawa Y., Kumae S., Hiraoka T., Yamaguchi K., Hamaguchi K., Uchida S. Isolation of glucagons-secreting cell lines by cloning insulinoma cells. In Vitro Cell Develop. Biol. 22:1986;120-126
-
(1986)
In Vitro Cell Develop. Biol.
, vol.22
, pp. 120-126
-
-
Takaki, R.1
Ono, J.2
Nakamura, M.3
Yokogawa, Y.4
Kumae, S.5
Hiraoka, T.6
Yamaguchi, K.7
Hamaguchi, K.8
Uchida, S.9
-
64
-
-
0026569910
-
Glucose transporter isotypes switch in T-antigen-transformed pancreatic beta cells growing in culture and in mice
-
Tal M., Thorens B., Surana M., Fleischer N., Lodish H.F., Hanahan D., Efrat S. Glucose transporter isotypes switch in T-antigen-transformed pancreatic beta cells growing in culture and in mice. Mol. Cell Biol. 12:1992;422-432
-
(1992)
Mol. Cell Biol.
, vol.12
, pp. 422-432
-
-
Tal, M.1
Thorens, B.2
Surana, M.3
Fleischer, N.4
Lodish, H.F.5
Hanahan, D.6
Efrat, S.7
-
65
-
-
17744372474
-
Beta-cell differentiation from a human pancreatic cell line in vitro and in vivo
-
de la Tour D., Halvorsen T., Demeterco C., Tyrberg B., Itkin-Ansari P., Loy M., Yoo S.J., Hao E., Bossie S., Levine F. Beta-cell differentiation from a human pancreatic cell line in vitro and in vivo. Mol. Endocrinol. 15:2001;476-483
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 476-483
-
-
De La Tour, D.1
Halvorsen, T.2
Demeterco, C.3
Tyrberg, B.4
Itkin-Ansari, P.5
Loy, M.6
Yoo, S.J.7
Hao, E.8
Bossie, S.9
Levine, F.10
-
66
-
-
0037645822
-
Discrete and complementary mechanisms of protection of beta-cells against cytokine-induced and oxidative damage achieved by bcl-2 overexpression and a cytokine selection strategy
-
Tran V.V., Chen G., Newgard C.B., Hohmeier H.E. Discrete and complementary mechanisms of protection of beta-cells against cytokine-induced and oxidative damage achieved by bcl-2 overexpression and a cytokine selection strategy. Diabetes. 52:2003;1423-1432
-
(2003)
Diabetes
, vol.52
, pp. 1423-1432
-
-
Tran, V.V.1
Chen, G.2
Newgard, C.B.3
Hohmeier, H.E.4
-
67
-
-
0031029972
-
Isolation and characterization of a cell line from the epithelial cells of the human fetal pancreas
-
Wang S., Beattie G.M., Mally M.I., Cirulli V., Itkin-Ansari P., Lopez A.D., Hayek A., Levine F. Isolation and characterization of a cell line from the epithelial cells of the human fetal pancreas. Cell Transplant. 6:1997;59-67
-
(1997)
Cell Transplant.
, vol.6
, pp. 59-67
-
-
Wang, S.1
Beattie, G.M.2
Mally, M.I.3
Cirulli, V.4
Itkin-Ansari, P.5
Lopez, A.D.6
Hayek, A.7
Levine, F.8
-
68
-
-
0029797647
-
Regulation of insulin secretion by phospholipase C
-
Zawalich W.S., Zawalich K.C. Regulation of insulin secretion by phospholipase C. Am. J. Physiol. 271:1996;E409-E416
-
(1996)
Am. J. Physiol.
, vol.271
-
-
Zawalich, W.S.1
Zawalich, K.C.2
-
69
-
-
0024533034
-
Insulin secretion and cAMP metabolism in HIT cells. Reciprocal and serial passage-dependent relationships
-
Zhang H.J., Walseth T.F., Robertson R.P. Insulin secretion and cAMP metabolism in HIT cells. Reciprocal and serial passage-dependent relationships. Diabetes. 38:1989;44-48
-
(1989)
Diabetes
, vol.38
, pp. 44-48
-
-
Zhang, H.J.1
Walseth, T.F.2
Robertson, R.P.3
-
70
-
-
0031802880
-
In vitro and in vivo evaluation of insulin-producing beta TC6-F7 cells in microcapsules
-
Zhou D., Sun A.M., Li X., Mamujee S.N., Vacek I., Georgiou J., Wheeler M.B. In vitro and in vivo evaluation of insulin-producing beta TC6-F7 cells in microcapsules. Am. J. Physiol. 274:1998;C1356-C1362
-
(1998)
Am. J. Physiol.
, vol.274
-
-
Zhou, D.1
Sun, A.M.2
Li, X.3
Mamujee, S.N.4
Vacek, I.5
Georgiou, J.6
Wheeler, M.B.7
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