메뉴 건너뛰기




Volumn 113, Issue , 2015, Pages 108-120

Metabolomics for laboratory diagnostics

Author keywords

Analytical techniques; Biological samples; Biomarkers; Laboratory diagnostics; Metabolomics

Indexed keywords

VOLATILE ORGANIC COMPOUND; BIOLOGICAL MARKER;

EID: 84939266359     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2014.12.017     Document Type: Review
Times cited : (307)

References (100)
  • 2
    • 0036500993 scopus 로고    scopus 로고
    • Systems biology: a brief overview
    • Kitano H. Systems biology: a brief overview. Science 2002, 295:1662-1664.
    • (2002) Science , vol.295 , pp. 1662-1664
    • Kitano, H.1
  • 3
    • 84869469815 scopus 로고    scopus 로고
    • Tandem mass spectrometry: a new platform for fluxomics
    • Peng L. Tandem mass spectrometry: a new platform for fluxomics. J. Proteomics Bioinform. 2012, 5:5-9.
    • (2012) J. Proteomics Bioinform. , vol.5 , pp. 5-9
    • Peng, L.1
  • 5
    • 79251595354 scopus 로고    scopus 로고
    • The role of metabolites and metabolomics in clinically applicable biomarkers of disease
    • Mamas M., Dunn W.B., Neyses L., Goodacre R. The role of metabolites and metabolomics in clinically applicable biomarkers of disease. Arch. Toxicol. 2011, 85:5-17.
    • (2011) Arch. Toxicol. , vol.85 , pp. 5-17
    • Mamas, M.1    Dunn, W.B.2    Neyses, L.3    Goodacre, R.4
  • 7
    • 0015111451 scopus 로고
    • Metabolic profiles: gas-phase methods for analysis of metabolites
    • Horning E.C., Horning M.G. Metabolic profiles: gas-phase methods for analysis of metabolites. Clin. Chem. 1971, 17:802-809.
    • (1971) Clin. Chem. , vol.17 , pp. 802-809
    • Horning, E.C.1    Horning, M.G.2
  • 8
    • 0345470490 scopus 로고
    • Human metabolic profiles obtained by GC and GC/MS
    • Horning E.C., Horning M.G. Human metabolic profiles obtained by GC and GC/MS. J. Chromatogr. Sci. 1971, 9:129-140.
    • (1971) J. Chromatogr. Sci. , vol.9 , pp. 129-140
    • Horning, E.C.1    Horning, M.G.2
  • 9
    • 0015131404 scopus 로고
    • Quantitative analysis of urine vapor and breath by gas-liquid partition chromatography
    • Pauling L., Robinson A.B., Teranishi R., Cary P. Quantitative analysis of urine vapor and breath by gas-liquid partition chromatography. Proc. Natl. Acad. Sci. U.S.A. 1971, 68:2374-2376.
    • (1971) Proc. Natl. Acad. Sci. U.S.A. , vol.68 , pp. 2374-2376
    • Pauling, L.1    Robinson, A.B.2    Teranishi, R.3    Cary, P.4
  • 10
    • 0032694577 scopus 로고    scopus 로고
    • Metabonomics: understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
    • Nicholson J.K., Lindon J.C., Holmes E. Metabonomics: understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 1999, 29:1181-1189.
    • (1999) Xenobiotica , vol.29 , pp. 1181-1189
    • Nicholson, J.K.1    Lindon, J.C.2    Holmes, E.3
  • 11
    • 0034959944 scopus 로고    scopus 로고
    • Combining genomics, metabolome analysis, and biochemical modeling to understand metabolic networks
    • Fiehn O. Combining genomics, metabolome analysis, and biochemical modeling to understand metabolic networks. Comp. Funct. Genom. 2001, 2:155-168.
    • (2001) Comp. Funct. Genom. , vol.2 , pp. 155-168
    • Fiehn, O.1
  • 14
    • 39149126712 scopus 로고    scopus 로고
    • Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts
    • Beckonert O., Keun H.C., Ebbels T.M.D., Bundy J., Holmes E., Lindon J.C., Nicholson J.K. Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts. Nat. Protoc. 2007, 2:2692-2703.
    • (2007) Nat. Protoc. , vol.2 , pp. 2692-2703
    • Beckonert, O.1    Keun, H.C.2    Ebbels, T.M.D.3    Bundy, J.4    Holmes, E.5    Lindon, J.C.6    Nicholson, J.K.7
  • 16
    • 48849084492 scopus 로고    scopus 로고
    • Metabolic footprinting in microbiology: methods and applications in functional genomics and biotechnology
    • Mapelli V., Olsson L., Nielsen J. Metabolic footprinting in microbiology: methods and applications in functional genomics and biotechnology. Trends Biotechnol. 2008, 2008(26):490-497.
    • (2008) Trends Biotechnol. , vol.2008 , Issue.26 , pp. 490-497
    • Mapelli, V.1    Olsson, L.2    Nielsen, J.3
  • 17
    • 41149120469 scopus 로고    scopus 로고
    • Analytical technologies for metabonomics and metabolomics, and multi-omic information recovery
    • Lindon J.C., Nicholson J.K. Analytical technologies for metabonomics and metabolomics, and multi-omic information recovery. TrAC: Trend Anal. Chem. 2008, 27:194-204.
    • (2008) TrAC: Trend Anal. Chem. , vol.27 , pp. 194-204
    • Lindon, J.C.1    Nicholson, J.K.2
  • 19
    • 1642345498 scopus 로고    scopus 로고
    • Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse
    • Coen M., Ruepp S.U., Lindon J.C., Nicholson J.K., Pognan F., Lenz E.M., Wilson I.D. Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse. J. Pharm. Biomed. Anal. 2004, 35:93-105.
    • (2004) J. Pharm. Biomed. Anal. , vol.35 , pp. 93-105
    • Coen, M.1    Ruepp, S.U.2    Lindon, J.C.3    Nicholson, J.K.4    Pognan, F.5    Lenz, E.M.6    Wilson, I.D.7
  • 20
    • 0347380960 scopus 로고    scopus 로고
    • 1H NMR analysis of whole cells of Thalassiosira pseudonana (Bacillariophyceae): broad range analysis of metabolic composition and nutritional value
    • 1H NMR analysis of whole cells of Thalassiosira pseudonana (Bacillariophyceae): broad range analysis of metabolic composition and nutritional value. J. Appl. Phycol. 2003, 15:533-542.
    • (2003) J. Appl. Phycol. , vol.15 , pp. 533-542
    • Chauton, M.S.1    Størseth, T.R.2    Johnsen, G.3
  • 21
    • 66349087823 scopus 로고    scopus 로고
    • Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics
    • Lindon J.C., Nicholson J.K. Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics. Annu. Rev. Anal. Chem. 2008, 1:45-49.
    • (2008) Annu. Rev. Anal. Chem. , vol.1 , pp. 45-49
    • Lindon, J.C.1    Nicholson, J.K.2
  • 23
    • 84889567618 scopus 로고    scopus 로고
    • Current practice of liquid chromatography-mass spectrometry in metabolomics and metabonomics
    • Gika H.G., Theodoridis G.A., Plumb R.S., Wilson I.D. Current practice of liquid chromatography-mass spectrometry in metabolomics and metabonomics. J. Pharm. Biomed. Anal. 2014, 87:12-25.
    • (2014) J. Pharm. Biomed. Anal. , vol.87 , pp. 12-25
    • Gika, H.G.1    Theodoridis, G.A.2    Plumb, R.S.3    Wilson, I.D.4
  • 24
    • 77950811675 scopus 로고    scopus 로고
    • Hydrophilic interaction chromatography coupled to MS for metabonomic/metabolomic studies
    • Spagou K., Tsoukali H., Raikos N., Gika H., Wilson I.D., Theodoridis G. Hydrophilic interaction chromatography coupled to MS for metabonomic/metabolomic studies. J. Sep. Sci. 2010, 33:716-727.
    • (2010) J. Sep. Sci. , vol.33 , pp. 716-727
    • Spagou, K.1    Tsoukali, H.2    Raikos, N.3    Gika, H.4    Wilson, I.D.5    Theodoridis, G.6
  • 25
    • 17444404226 scopus 로고    scopus 로고
    • High resolution ultra performance liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies
    • Wilson I.D., Nicholson J.K., Castro-Perez J., Granger J.H., Johnson K.A., Smith B.W., Plumb R.S. High resolution ultra performance liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies. J. Proteome Res. 2005, 4(March-April (2)):591-598.
    • (2005) J. Proteome Res. , vol.4 , Issue.March April 2 , pp. 591-598
    • Wilson, I.D.1    Nicholson, J.K.2    Castro-Perez, J.3    Granger, J.H.4    Johnson, K.A.5    Smith, B.W.6    Plumb, R.S.7
  • 26
    • 84918815926 scopus 로고    scopus 로고
    • UPLC-Q-TOF/MS based metabolomic profiling of serum and urine of hyperlipidemic rats induced by high fat diet
    • Wu Q., Zhang H., Dong X., Chen X.F., Zhu Z.Y., Hong Z.Y., Chai Y.F. UPLC-Q-TOF/MS based metabolomic profiling of serum and urine of hyperlipidemic rats induced by high fat diet. J. Pharm. Anal. 2014, 4:360-367.
    • (2014) J. Pharm. Anal. , vol.4 , pp. 360-367
    • Wu, Q.1    Zhang, H.2    Dong, X.3    Chen, X.F.4    Zhu, Z.Y.5    Hong, Z.Y.6    Chai, Y.F.7
  • 27
    • 16244402990 scopus 로고    scopus 로고
    • Metabolomics: current analytical platforms and methodologies
    • Dunn W.B., Ellis D.I. Metabolomics: current analytical platforms and methodologies. Trends Anal. Chem. 2005, 24:285-294.
    • (2005) Trends Anal. Chem. , vol.24 , pp. 285-294
    • Dunn, W.B.1    Ellis, D.I.2
  • 28
    • 83455203337 scopus 로고    scopus 로고
    • Modern analytical techniques in metabolomics analysis
    • Zhang A., Sun H., Wang P., Han Y., Wang X. Modern analytical techniques in metabolomics analysis. Analyst 2012, 137:293-300.
    • (2012) Analyst , vol.137 , pp. 293-300
    • Zhang, A.1    Sun, H.2    Wang, P.3    Han, Y.4    Wang, X.5
  • 29
    • 70349106852 scopus 로고    scopus 로고
    • Polar anionic metabolome analysis by nano-LC/MS with a metal chelating agent
    • Myint K.T., Uehara T., Aoshima K., Oda Y. Polar anionic metabolome analysis by nano-LC/MS with a metal chelating agent. Anal. Chem. 2009, 81:7766-7772.
    • (2009) Anal. Chem. , vol.81 , pp. 7766-7772
    • Myint, K.T.1    Uehara, T.2    Aoshima, K.3    Oda, Y.4
  • 31
    • 72449186517 scopus 로고    scopus 로고
    • FiehnLib-mass spectral and retention index libraries for metabolomics based on quadrupole and time-of-flight gas chromatography/mass spectrometry
    • Kind T., Wohlgemuth G., Lee D.Y., Lu Y., Palazoglu M., Shahbaz S., Fiehn O. FiehnLib-mass spectral and retention index libraries for metabolomics based on quadrupole and time-of-flight gas chromatography/mass spectrometry. Anal. Chem. 2009, 81:10038-10048.
    • (2009) Anal. Chem. , vol.81 , pp. 10038-10048
    • Kind, T.1    Wohlgemuth, G.2    Lee, D.Y.3    Lu, Y.4    Palazoglu, M.5    Shahbaz, S.6    Fiehn, O.7
  • 32
    • 33847358695 scopus 로고    scopus 로고
    • Analytical strategies in metabonomics
    • Lenz E.M., Wilson I.D. Analytical strategies in metabonomics. J. Proteome Res. 2007, 6:443-458.
    • (2007) J. Proteome Res. , vol.6 , pp. 443-458
    • Lenz, E.M.1    Wilson, I.D.2
  • 33
    • 22744452937 scopus 로고    scopus 로고
    • Statistical methods for comparing comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry results: metabolomic analysis of mouse tissue extracts
    • Shellie R.A., Welthagen W., Zrostlikova J., Spranger J., Ristow M., Fiehn O., Zimmermann R. Statistical methods for comparing comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry results: metabolomic analysis of mouse tissue extracts. J. Chromatogr. A 2005, 1086:83-90.
    • (2005) J. Chromatogr. A , vol.1086 , pp. 83-90
    • Shellie, R.A.1    Welthagen, W.2    Zrostlikova, J.3    Spranger, J.4    Ristow, M.5    Fiehn, O.6    Zimmermann, R.7
  • 34
    • 84920138029 scopus 로고    scopus 로고
    • CE-MS for metabolomics: developments and applications in the period 2012-2014
    • Ramautar R., Somsen G.W., de Jong G.J. CE-MS for metabolomics: developments and applications in the period 2012-2014. Electrophoresis 2014, 10.1002/elps.201400388.
    • (2014) Electrophoresis
    • Ramautar, R.1    Somsen, G.W.2    de Jong, G.J.3
  • 35
    • 84888371490 scopus 로고    scopus 로고
    • Method development and validation for rat serum fingerprinting with CE-MS: application to ventilator-induced-lung-injury study
    • Naz S., Garcia A., Rusak M., Barbas C. Method development and validation for rat serum fingerprinting with CE-MS: application to ventilator-induced-lung-injury study. Anal. Bioanal. Chem. 2013, 405:4849-4858.
    • (2013) Anal. Bioanal. Chem. , vol.405 , pp. 4849-4858
    • Naz, S.1    Garcia, A.2    Rusak, M.3    Barbas, C.4
  • 36
    • 79960732246 scopus 로고    scopus 로고
    • Metabolomic assessment with CE-MS of the nutraceutical effect of Cystoseira spp. extracts in an animal model
    • Moraes E.P., Rupérez F.J., Plaza M., Herrero M., Barbas C. Metabolomic assessment with CE-MS of the nutraceutical effect of Cystoseira spp. extracts in an animal model. Electrophoresis 2011, 32:2055-2062.
    • (2011) Electrophoresis , vol.32 , pp. 2055-2062
    • Moraes, E.P.1    Rupérez, F.J.2    Plaza, M.3    Herrero, M.4    Barbas, C.5
  • 37
    • 18844406001 scopus 로고    scopus 로고
    • Measuring the metabolome: current analytical technologies
    • Dunn W.B., Bailey N.J., Johnson H.E. Measuring the metabolome: current analytical technologies. Analyst 2005, 130:606-625.
    • (2005) Analyst , vol.130 , pp. 606-625
    • Dunn, W.B.1    Bailey, N.J.2    Johnson, H.E.3
  • 39
    • 84860386341 scopus 로고    scopus 로고
    • Double-check: validation of diagnostic statistics for PLS-DA models in metabolomics studies
    • Szymańska E., Saccenti E., Smilde A.K., Westerhuis J.A. Double-check: validation of diagnostic statistics for PLS-DA models in metabolomics studies. Metabolomics 2012, 8:3-16.
    • (2012) Metabolomics , vol.8 , pp. 3-16
    • Szymańska, E.1    Saccenti, E.2    Smilde, A.K.3    Westerhuis, J.A.4
  • 40
    • 84890226269 scopus 로고    scopus 로고
    • Multivariate analysis in metabolomics
    • Worley B., Powers R. Multivariate analysis in metabolomics. Curr. Metabolomics 2013, 1:92-107.
    • (2013) Curr. Metabolomics , vol.1 , pp. 92-107
    • Worley, B.1    Powers, R.2
  • 41
    • 84865593022 scopus 로고    scopus 로고
    • Serum metabolomics as a novel diagnostic approach for disease: a systematic review
    • Zhang A., Sun H., Wang X. Serum metabolomics as a novel diagnostic approach for disease: a systematic review. Anal. Bioanal. Chem. 2012, 404:1239-1245.
    • (2012) Anal. Bioanal. Chem. , vol.404 , pp. 1239-1245
    • Zhang, A.1    Sun, H.2    Wang, X.3
  • 42
    • 84890858348 scopus 로고    scopus 로고
    • A serum nuclear magnetic resonance-based metabolomic signature of advanced metastatic human breast cancer
    • Jobard E., Pontoizeau C., Blaise B.J., Bachelot T., Herrmann B.E., Trédan O. A serum nuclear magnetic resonance-based metabolomic signature of advanced metastatic human breast cancer. Cancer Lett. 2014, 343:33-41.
    • (2014) Cancer Lett. , vol.343 , pp. 33-41
    • Jobard, E.1    Pontoizeau, C.2    Blaise, B.J.3    Bachelot, T.4    Herrmann, B.E.5    Trédan, O.6
  • 44
    • 84902579080 scopus 로고    scopus 로고
    • Biomarker identification and pathway analysis by serum metabolomics of childhood acute lymphoblastic leukemia
    • Bai Y., Zhang H., Sun X., Sunb C., Ren L. Biomarker identification and pathway analysis by serum metabolomics of childhood acute lymphoblastic leukemia. Clin. Chim. Acta 2014, 25:207-216.
    • (2014) Clin. Chim. Acta , vol.25 , pp. 207-216
    • Bai, Y.1    Zhang, H.2    Sun, X.3    Sunb, C.4    Ren, L.5
  • 45
    • 84901639526 scopus 로고    scopus 로고
    • Combination of metabolomic and phospholipid-profiling approaches for the study of Alzheimer's disease
    • González-Domínguez R., García-Barrera T., Luis Gómez-Ariza J. Combination of metabolomic and phospholipid-profiling approaches for the study of Alzheimer's disease. J. Proteomics 2014, 104:37-47.
    • (2014) J. Proteomics , vol.104 , pp. 37-47
    • González-Domínguez, R.1    García-Barrera, T.2    Luis Gómez-Ariza, J.3
  • 46
    • 84913592920 scopus 로고    scopus 로고
    • Metabolomic profiling of serum in the progression of Alzheimer's disease by capillary electrophoresis-mass spectrometry
    • Gonzalez-Dominguez R., Garcia A., Garcia-Barrera T., Barbas C., Gomez-Ariza J.L. Metabolomic profiling of serum in the progression of Alzheimer's disease by capillary electrophoresis-mass spectrometry. Electrophoresis 2014, 35:3321-3330.
    • (2014) Electrophoresis , vol.35 , pp. 3321-3330
    • Gonzalez-Dominguez, R.1    Garcia, A.2    Garcia-Barrera, T.3    Barbas, C.4    Gomez-Ariza, J.L.5
  • 51
    • 84857527060 scopus 로고    scopus 로고
    • Metabolomics with LC-QTOF-MS permits the prediction of disease stage in aortic abdominal aneurysm based on plasma metabolic fingerprint
    • Ciborowski M., Teul J., Martin-Ventura J.L., Egido J., Barbas C. Metabolomics with LC-QTOF-MS permits the prediction of disease stage in aortic abdominal aneurysm based on plasma metabolic fingerprint. PLoS ONE 2012, 7:e31982. 10.1371/journal.pone.0031982.
    • (2012) PLoS ONE , vol.7 , pp. e31982
    • Ciborowski, M.1    Teul, J.2    Martin-Ventura, J.L.3    Egido, J.4    Barbas, C.5
  • 54
    • 84877888815 scopus 로고    scopus 로고
    • Identification of altered metabolic pathways in plasma and CSF in mild cognitive impairment and Alzheimer's Disease using metabolomics
    • Trushina E., Dutta T., Persson X.M.T., Mielke M.M., Petersen R.C. Identification of altered metabolic pathways in plasma and CSF in mild cognitive impairment and Alzheimer's Disease using metabolomics. PLoS ONE 2013, 8:e63644. 10.1371/journal.pone.0063644.
    • (2013) PLoS ONE , vol.8 , pp. e63644
    • Trushina, E.1    Dutta, T.2    Persson, X.M.T.3    Mielke, M.M.4    Petersen, R.C.5
  • 55
    • 79953737346 scopus 로고    scopus 로고
    • Saliva: diagnostics and therapeutic perspectives
    • Spielmann N., Wong D.T. Saliva: diagnostics and therapeutic perspectives. Oral Dis. 2011, 17:345-354.
    • (2011) Oral Dis. , vol.17 , pp. 345-354
    • Spielmann, N.1    Wong, D.T.2
  • 57
    • 0033920686 scopus 로고    scopus 로고
    • Biochemical composition and electrolyte balance of uinstimulated whole human saliva
    • Rehak N.N., Cecco S.A., Csako G. Biochemical composition and electrolyte balance of uinstimulated whole human saliva. Clin. Chem. Lab. Med. 2000, 38:335-343.
    • (2000) Clin. Chem. Lab. Med. , vol.38 , pp. 335-343
    • Rehak, N.N.1    Cecco, S.A.2    Csako, G.3
  • 58
    • 84862807259 scopus 로고    scopus 로고
    • Saliva: a potential media for disease diagnostics and monitoring
    • Liu J., Duan Y. Saliva: a potential media for disease diagnostics and monitoring. Oral Oncol. 2012, 48:569-577.
    • (2012) Oral Oncol. , vol.48 , pp. 569-577
    • Liu, J.1    Duan, Y.2
  • 59
    • 84907164016 scopus 로고    scopus 로고
    • Emerging salivary biomarkers by mass spectrometry
    • Wang Q., Yu Q., Lin Q., Duan Y. Emerging salivary biomarkers by mass spectrometry. Clin. Chim. Acta 2015, 438:214-221.
    • (2015) Clin. Chim. Acta , vol.438 , pp. 214-221
    • Wang, Q.1    Yu, Q.2    Lin, Q.3    Duan, Y.4
  • 60
    • 84871266558 scopus 로고    scopus 로고
    • Development of isotope labeling LC-MS for human salivary metabolomics and application to profiling metabolome changes associated with mild cognitive impairment
    • Zheng J., Dixon R.A., Li J. Development of isotope labeling LC-MS for human salivary metabolomics and application to profiling metabolome changes associated with mild cognitive impairment. Anal. Chem. 2012, 84:10802-10811.
    • (2012) Anal. Chem. , vol.84 , pp. 10802-10811
    • Zheng, J.1    Dixon, R.A.2    Li, J.3
  • 61
    • 70449708959 scopus 로고    scopus 로고
    • Saliva as a tool for oral cancer diagnosis and prognosis
    • Nagler R.M. Saliva as a tool for oral cancer diagnosis and prognosis. Oral Oncol. 2009, 45:1006-1010.
    • (2009) Oral Oncol. , vol.45 , pp. 1006-1010
    • Nagler, R.M.1
  • 62
    • 84871784703 scopus 로고    scopus 로고
    • Saliva metabolomics opens door to biomarker discovery, disease diagnosis and treatment
    • Zhang A., Sun H., Wang X. Saliva metabolomics opens door to biomarker discovery, disease diagnosis and treatment. Appl. Biochem. Biotechnol. 2012, 168:1718-1727.
    • (2012) Appl. Biochem. Biotechnol. , vol.168 , pp. 1718-1727
    • Zhang, A.1    Sun, H.2    Wang, X.3
  • 63
    • 77949297718 scopus 로고    scopus 로고
    • Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles
    • Sugimoto M., Wong D.T., Hirayama A., Soga T., Tomita M. Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles. Metabolomics 2010, 6:78-95.
    • (2010) Metabolomics , vol.6 , pp. 78-95
    • Sugimoto, M.1    Wong, D.T.2    Hirayama, A.3    Soga, T.4    Tomita, M.5
  • 64
    • 84888872781 scopus 로고    scopus 로고
    • Measurement of salivary metabolite biomarkers for early monitoring of oral cancer with ultra-performance liquid chromatography-mass spectrometry
    • Wang Q., Gao P., Cheng F., Wang X., Duan Y. Measurement of salivary metabolite biomarkers for early monitoring of oral cancer with ultra-performance liquid chromatography-mass spectrometry. Talanta 2014, 119:299-305.
    • (2014) Talanta , vol.119 , pp. 299-305
    • Wang, Q.1    Gao, P.2    Cheng, F.3    Wang, X.4    Duan, Y.5
  • 65
    • 84923383232 scopus 로고    scopus 로고
    • The early diagnosis and monitoring of oral squamous cell carcinoma via saliva metabolomics
    • Wang Q., Gao P., Wang X., Duan Y. The early diagnosis and monitoring of oral squamous cell carcinoma via saliva metabolomics. Sci. Rep. 2014, 10.1038/srep06802.
    • (2014) Sci. Rep.
    • Wang, Q.1    Gao, P.2    Wang, X.3    Duan, Y.4
  • 69
    • 84884986515 scopus 로고    scopus 로고
    • Capillary electrophoresis-mass spectrometry-based metabolome analysis of serum and saliva from neurogenerative dementia patients
    • Tsuruoka M., Hara J., Hirayama A., Sugimoto M., Soga T., Shankle W.R., Tomita M. Capillary electrophoresis-mass spectrometry-based metabolome analysis of serum and saliva from neurogenerative dementia patients. Electrophoresis 2013, 34:2865-2872.
    • (2013) Electrophoresis , vol.34 , pp. 2865-2872
    • Tsuruoka, M.1    Hara, J.2    Hirayama, A.3    Sugimoto, M.4    Soga, T.5    Shankle, W.R.6    Tomita, M.7
  • 70
    • 84863992311 scopus 로고    scopus 로고
    • Dynamics of salivary proteins and metabolites during extreme endurance sports - a case study
    • Zauber H., Mosler S., von Hesberg A., Schulze W.X. Dynamics of salivary proteins and metabolites during extreme endurance sports - a case study. Proteomics 2012, 12:2221-2235.
    • (2012) Proteomics , vol.12 , pp. 2221-2235
    • Zauber, H.1    Mosler, S.2    von Hesberg, A.3    Schulze, W.X.4
  • 73
    • 84863094398 scopus 로고    scopus 로고
    • Study of sample preparation for metabolomics profiling of human saliva liquid chromatography-time of flight/mass spectrometry
    • Alvarez-Sanchez B., Priego-Capote F., Luque de Castro M.D. Study of sample preparation for metabolomics profiling of human saliva liquid chromatography-time of flight/mass spectrometry. J. Chromatogr. A 2012, 1248:178-181.
    • (2012) J. Chromatogr. A , vol.1248 , pp. 178-181
    • Alvarez-Sanchez, B.1    Priego-Capote, F.2    Luque de Castro, M.D.3
  • 76
    • 84869195682 scopus 로고    scopus 로고
    • Preparation of urine samples prior to targeted or untargeted metabolomics mass-spectrometry analysis
    • Fernández-Peralbo M.A., Luque de Castro M.D. Preparation of urine samples prior to targeted or untargeted metabolomics mass-spectrometry analysis. Trends Anal. Chem. 2012, 41:75-85.
    • (2012) Trends Anal. Chem. , vol.41 , pp. 75-85
    • Fernández-Peralbo, M.A.1    Luque de Castro, M.D.2
  • 77
    • 84891908343 scopus 로고    scopus 로고
    • Determination of pterins in urine by HPLC with UV and fluorescent detection using different types of chromatographic stationary phases (HILIC, RP C8, RP C18)
    • Kośliński P., Jarzemski P., Markuszewski M.J., Kaliszan R. Determination of pterins in urine by HPLC with UV and fluorescent detection using different types of chromatographic stationary phases (HILIC, RP C8, RP C18). J. Pharm. Biomed. Anal. 2014, 91:37-45.
    • (2014) J. Pharm. Biomed. Anal. , vol.91 , pp. 37-45
    • Kośliński, P.1    Jarzemski, P.2    Markuszewski, M.J.3    Kaliszan, R.4
  • 80
    • 84877140209 scopus 로고    scopus 로고
    • Quantification of candidate prostate cancer metabolite biomarkers in urine using dispersive derivatization liquid-liquid microextraction followed by gas and liquid chromatography-mass spectrometry
    • Shamsipur M., Naseri M.T., Babri M. Quantification of candidate prostate cancer metabolite biomarkers in urine using dispersive derivatization liquid-liquid microextraction followed by gas and liquid chromatography-mass spectrometry. J. Pharm. Biomed. Anal. 2013, 81-82:65-75.
    • (2013) J. Pharm. Biomed. Anal. , vol.81-82 , pp. 65-75
    • Shamsipur, M.1    Naseri, M.T.2    Babri, M.3
  • 81
    • 84869084661 scopus 로고    scopus 로고
    • Monitoring potential prostate cancer biomarkers in urine by capillary electrophoresis-tandem mass spectrometry
    • Soliman L.C., Hui Y., Hewavitharana A.K., Chen D.D.Y. Monitoring potential prostate cancer biomarkers in urine by capillary electrophoresis-tandem mass spectrometry. J. Chromatogr. A 2012, 1267:162-169.
    • (2012) J. Chromatogr. A , vol.1267 , pp. 162-169
    • Soliman, L.C.1    Hui, Y.2    Hewavitharana, A.K.3    Chen, D.D.Y.4
  • 82
    • 84887202472 scopus 로고    scopus 로고
    • Searching for urine biomarkers of bladder cancer recurrence using a liquid chromatography-mass spectrometry and capillary electrophoresis-mass spectrometry metabolomics approach
    • Alberice J.V., Amaral A.F.S., Armitage E.G., Lorente J.A., Algaba F., Carrilho E., Marquez M., Garcia A., Malats N., Barbas C. Searching for urine biomarkers of bladder cancer recurrence using a liquid chromatography-mass spectrometry and capillary electrophoresis-mass spectrometry metabolomics approach. J. Chromatogr. A 2013, 1318:163-170.
    • (2013) J. Chromatogr. A , vol.1318 , pp. 163-170
    • Alberice, J.V.1    Amaral, A.F.S.2    Armitage, E.G.3    Lorente, J.A.4    Algaba, F.5    Carrilho, E.6    Marquez, M.7    Garcia, A.8    Malats, N.9    Barbas, C.10
  • 85
    • 84892805927 scopus 로고    scopus 로고
    • Pancreatic ductal adenocarcinoma is associated with a distinct urinary metabolomics signature
    • Davis V.W., Schiller D.E., Eurich D., Bathe O.F., Sawyer M.B. Pancreatic ductal adenocarcinoma is associated with a distinct urinary metabolomics signature. Ann. Surg. Oncol. 2013, 20:415-423.
    • (2013) Ann. Surg. Oncol. , vol.20 , pp. 415-423
    • Davis, V.W.1    Schiller, D.E.2    Eurich, D.3    Bathe, O.F.4    Sawyer, M.B.5
  • 87
    • 84856355144 scopus 로고    scopus 로고
    • Solid phase microextraction, mass spectrometry and metabolomic approaches for detection of potential urinary cancer biomarkers - a powerful strategy for breast cancer diagnosis
    • Silva C.L., Passos M., Câmara J.S. Solid phase microextraction, mass spectrometry and metabolomic approaches for detection of potential urinary cancer biomarkers - a powerful strategy for breast cancer diagnosis. Talanta 2012, 89:360-368.
    • (2012) Talanta , vol.89 , pp. 360-368
    • Silva, C.L.1    Passos, M.2    Câmara, J.S.3
  • 88
    • 84902252993 scopus 로고    scopus 로고
    • Analysis of volatile human urinary metabolome by solid-phase microextraction in combination with gas chromatography-mass spectrometry for biomarker discovery: application in a pilot study to discriminate patients with renal cell carcinoma
    • Monteiro M., Carvalho M., Henrique R., Jeronimo C., Moreira N., Bastos M.L., de Pinho P.G. Analysis of volatile human urinary metabolome by solid-phase microextraction in combination with gas chromatography-mass spectrometry for biomarker discovery: application in a pilot study to discriminate patients with renal cell carcinoma. Eur. J. Cancer 2014, 50:1993-2002.
    • (2014) Eur. J. Cancer , vol.50 , pp. 1993-2002
    • Monteiro, M.1    Carvalho, M.2    Henrique, R.3    Jeronimo, C.4    Moreira, N.5    Bastos, M.L.6    de Pinho, P.G.7
  • 89
    • 84885006315 scopus 로고    scopus 로고
    • Detection of volatile organic compounds as biomarkers in breath analysis by different analytical techniques
    • Buszewski B., Grzywinski D., Ligor T., Stacewicz T., Bielecki Z., Wojtas J. Detection of volatile organic compounds as biomarkers in breath analysis by different analytical techniques. Bioanalysis 2013, 5:2287-2306.
    • (2013) Bioanalysis , vol.5 , pp. 2287-2306
    • Buszewski, B.1    Grzywinski, D.2    Ligor, T.3    Stacewicz, T.4    Bielecki, Z.5    Wojtas, J.6
  • 92
    • 84903160331 scopus 로고    scopus 로고
    • Volatile organic metabolites identify patients with breast cancer, cyclomastopathy, and mammary gland fibroma
    • Wang Ch., Sun B., Guo L., Wang X., Ke Ch., Liu S., Zhao W., Luo S., Guo Z., Zhang Y., Xu G., Li E. Volatile organic metabolites identify patients with breast cancer, cyclomastopathy, and mammary gland fibroma. Sci. Rep. 2014, 4. 10.1038/srep05383.
    • (2014) Sci. Rep. , vol.4
    • Wang, C.1    Sun, B.2    Guo, L.3    Wang, X.4    Ke, C.5    Liu, S.6    Zhao, W.7    Luo, S.8    Guo, Z.9    Zhang, Y.10    Xu, G.11    Li, E.12
  • 93
    • 84885011607 scopus 로고    scopus 로고
    • Metabolomics pilot study to identify volatile organic compound markers of childhood asthma in exhaled breath
    • Gahleitner F., Guallar-Hoyas C., Beardsmore C.S., Pandya H.C., Thomas C.L.P. Metabolomics pilot study to identify volatile organic compound markers of childhood asthma in exhaled breath. Bioanalysis 2014, 5:2239-2247.
    • (2014) Bioanalysis , vol.5 , pp. 2239-2247
    • Gahleitner, F.1    Guallar-Hoyas, C.2    Beardsmore, C.S.3    Pandya, H.C.4    Thomas, C.L.P.5
  • 94
    • 84956584662 scopus 로고    scopus 로고
    • Noninvasive detection of lung cancer using exhaled breath
    • Fu X-A., Li M., Knipp R.J., Nantz M.H., Bousamra M. Noninvasive detection of lung cancer using exhaled breath. Cancer Med. 2014, 3:174-181.
    • (2014) Cancer Med. , vol.3 , pp. 174-181
    • Fu, X.-A.1    Li, M.2    Knipp, R.J.3    Nantz, M.H.4    Bousamra, M.5
  • 96
    • 84882632229 scopus 로고    scopus 로고
    • Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics
    • Huang Q., Tan Y., Yin P., Ye G., Gao P., Lu X., Wang H., Xu G. Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics. Cancer Res. 2013, 73:4992-5002.
    • (2013) Cancer Res. , vol.73 , pp. 4992-5002
    • Huang, Q.1    Tan, Y.2    Yin, P.3    Ye, G.4    Gao, P.5    Lu, X.6    Wang, H.7    Xu, G.8
  • 98
    • 84928165363 scopus 로고    scopus 로고
    • Metabolic profiles are principally different between cancers of the liver pancreas and breast
    • Budhu A., Terenuma A., Zhang G., Hussain S.P., Ambs S., Wang X.W. Metabolic profiles are principally different between cancers of the liver pancreas and breast. Int. J. Biol. Sci. 2014, 10:966-972.
    • (2014) Int. J. Biol. Sci. , vol.10 , pp. 966-972
    • Budhu, A.1    Terenuma, A.2    Zhang, G.3    Hussain, S.P.4    Ambs, S.5    Wang, X.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.