-
1
-
-
84863702343
-
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
-
T.A. Wynn, and T.R. Ramalingam Mechanisms of fibrosis: therapeutic translation for fibrotic disease Nat. Med. 18 2012 1028 1040
-
(2012)
Nat. Med.
, vol.18
, pp. 1028-1040
-
-
Wynn, T.A.1
Ramalingam, T.R.2
-
2
-
-
38549159026
-
Cellular and molecular mechanisms of fibrosis
-
T.A. Wynn Cellular and molecular mechanisms of fibrosis J. Pathol. 214 2008 199 210
-
(2008)
J. Pathol.
, vol.214
, pp. 199-210
-
-
Wynn, T.A.1
-
4
-
-
84859073207
-
Recent developments in myofibroblast biology: paradigms for connective tissue remodeling
-
B. Hinz, S.H. Phan, V.J. Thannickal, M. Prunotto, A. Desmouliere, J. Varga, O. De Wever, M. Mareel, and G. Gabbiani Recent developments in myofibroblast biology: paradigms for connective tissue remodeling Am. J. Pathol. 180 2012 1340 1355
-
(2012)
Am. J. Pathol.
, vol.180
, pp. 1340-1355
-
-
Hinz, B.1
Phan, S.H.2
Thannickal, V.J.3
Prunotto, M.4
Desmouliere, A.5
Varga, J.6
De Wever, O.7
Mareel, M.8
Gabbiani, G.9
-
5
-
-
33847348491
-
Systemic sclerosis: a prototypic multisystem fibrotic disorder
-
J. Varga, and D. Abraham Systemic sclerosis: a prototypic multisystem fibrotic disorder J. Clin. Invest. 117 2007 557 567
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 557-567
-
-
Varga, J.1
Abraham, D.2
-
6
-
-
84996050651
-
Morphologic changes in the digital arteries of patients with progressive systemic sclerosis (scleroderma) and Raynaud phenomenon
-
G.P. Rodnan, R.L. Myerowitz, and G.O. Justh Morphologic changes in the digital arteries of patients with progressive systemic sclerosis (scleroderma) and Raynaud phenomenon Medicine (Baltimore) 59 1980 393 408
-
(1980)
Medicine (Baltimore)
, vol.59
, pp. 393-408
-
-
Rodnan, G.P.1
Myerowitz, R.L.2
Justh, G.O.3
-
7
-
-
77957668307
-
Animal models of systemic sclerosis: prospects and limitations
-
C. Beyer, G. Schett, O. Distler, and J.H. Distler Animal models of systemic sclerosis: prospects and limitations Arthritis Rheum. 62 2010 2831 2844
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 2831-2844
-
-
Beyer, C.1
Schett, G.2
Distler, O.3
Distler, J.H.4
-
8
-
-
73449115656
-
Transcription factor fos-related antigen-2 induces progressive peripheral vasculopathy in mice closely resembling human systemic sclerosis
-
B. Maurer, N. Busch, A. Jungel, M. Pileckyte, R.E. Gay, B.A. Michel, G. Schett, S. Gay, J. Distler, and O. Distler Transcription factor fos-related antigen-2 induces progressive peripheral vasculopathy in mice closely resembling human systemic sclerosis Circulation 120 2009 2367 2376
-
(2009)
Circulation
, vol.120
, pp. 2367-2376
-
-
Maurer, B.1
Busch, N.2
Jungel, A.3
Pileckyte, M.4
Gay, R.E.5
Michel, B.A.6
Schett, G.7
Gay, S.8
Distler, J.9
Distler, O.10
-
9
-
-
0026439371
-
Significance of plasma endothelin-1 levels in patients with systemic sclerosis
-
K. Yamane, T. Miyauchi, N. Suzuki, T. Yuhara, T. Akama, H. Suzuki, and H. Kashiwagi Significance of plasma endothelin-1 levels in patients with systemic sclerosis J. Rheumatol. 19 1992 1566 1571
-
(1992)
J. Rheumatol.
, vol.19
, pp. 1566-1571
-
-
Yamane, K.1
Miyauchi, T.2
Suzuki, N.3
Yuhara, T.4
Akama, T.5
Suzuki, H.6
Kashiwagi, H.7
-
10
-
-
77649147853
-
Endothelin 1 contributes to the effect of transforming growth factor beta1 on wound repair and skin fibrosis
-
D. Lagares, R.A. Garcia-Fernandez, C.L. Jimenez, N. Magan-Marchal, O. Busnadiego, S. Lamas, and F. Rodriguez-Pascual Endothelin 1 contributes to the effect of transforming growth factor beta1 on wound repair and skin fibrosis Arthritis Rheum. 62 2010 878 889
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 878-889
-
-
Lagares, D.1
Garcia-Fernandez, R.A.2
Jimenez, C.L.3
Magan-Marchal, N.4
Busnadiego, O.5
Lamas, S.6
Rodriguez-Pascual, F.7
-
11
-
-
74449089564
-
Improvement of bleomycin-induced pulmonary hypertension and pulmonary fibrosis by the endothelin receptor antagonist Bosentan
-
S. Schroll, M. Arzt, D. Sebah, M. Nuchterlein, F. Blumberg, and M. Pfeifer Improvement of bleomycin-induced pulmonary hypertension and pulmonary fibrosis by the endothelin receptor antagonist Bosentan Respir. Physiol. Neurobiol. 170 2010 32 36
-
(2010)
Respir. Physiol. Neurobiol.
, vol.170
, pp. 32-36
-
-
Schroll, S.1
Arzt, M.2
Sebah, D.3
Nuchterlein, M.4
Blumberg, F.5
Pfeifer, M.6
-
12
-
-
0032056141
-
Effect of endothelin receptor antagonists (BQ-485, Ro 47-0203) on collagen deposition during the development of bleomycin-induced pulmonary fibrosis in rats
-
S.E. Mutsaers, R.P. Marshall, N.R. Goldsack, G.J. Laurent, and R.J. McAnulty Effect of endothelin receptor antagonists (BQ-485, Ro 47-0203) on collagen deposition during the development of bleomycin-induced pulmonary fibrosis in rats Pulm. Pharmacol. Ther. 11 1998 221 225
-
(1998)
Pulm. Pharmacol. Ther.
, vol.11
, pp. 221-225
-
-
Mutsaers, S.E.1
Marshall, R.P.2
Goldsack, N.R.3
Laurent, G.J.4
McAnulty, R.J.5
-
13
-
-
77954222367
-
Randomized, prospective, placebo-controlled trial of bosentan in interstitial lung disease secondary to systemic sclerosis
-
J.R. Seibold, C.P. Denton, D.E. Furst, L. Guillevin, L.J. Rubin, A. Wells, M. Matucci Cerinic, G. Riemekasten, P. Emery, H. Chadha-Boreham, P. Charef, S. Roux, and C.M. Black Randomized, prospective, placebo-controlled trial of bosentan in interstitial lung disease secondary to systemic sclerosis Arthritis Rheum. 62 2010 2101 2108
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 2101-2108
-
-
Seibold, J.R.1
Denton, C.P.2
Furst, D.E.3
Guillevin, L.4
Rubin, L.J.5
Wells, A.6
Matucci Cerinic, M.7
Riemekasten, G.8
Emery, P.9
Chadha-Boreham, H.10
Charef, P.11
Roux, S.12
Black, C.M.13
-
14
-
-
80053501626
-
Effect of Bosentan on systemic sclerosis-associated interstitial lung disease ineligible for cyclophosphamide therapy: a prospective open-label study
-
Y. Furuya, and M. Kuwana Effect of Bosentan on systemic sclerosis-associated interstitial lung disease ineligible for cyclophosphamide therapy: a prospective open-label study J. Rheumatol. 38 2011 2186 2192
-
(2011)
J. Rheumatol.
, vol.38
, pp. 2186-2192
-
-
Furuya, Y.1
Kuwana, M.2
-
15
-
-
0028147645
-
Intravenous iloprost infusion in patients with Raynaud phenomenon secondary to systemic sclerosis. A multicenter, placebo-controlled, double-blind study
-
F.M. Wigley, R.A. Wise, J.R. Seibold, D.A. McCloskey, G. Kujala, T.A. Medsger Jr., V.D. Steen, J. Varga, S. Jimenez, M. Mayes, P.J. Clements, S.R. Weiner, J. Porter, M. Ellman, C. Wise, L.D. Kaufman, J. Williams, and W. Dole Intravenous iloprost infusion in patients with Raynaud phenomenon secondary to systemic sclerosis. A multicenter, placebo-controlled, double-blind study Ann. Intern. Med. 120 1994 199 206
-
(1994)
Ann. Intern. Med.
, vol.120
, pp. 199-206
-
-
Wigley, F.M.1
Wise, R.A.2
Seibold, J.R.3
McCloskey, D.A.4
Kujala, G.5
Medsger, T.A.6
Steen, V.D.7
Varga, J.8
Jimenez, S.9
Mayes, M.10
Clements, P.J.11
Weiner, S.R.12
Porter, J.13
Ellman, M.14
Wise, C.15
Kaufman, L.D.16
Williams, J.17
Dole, W.18
-
16
-
-
84940023827
-
Stimulators of soluble guanylate cyclase (sGC) inhibit experimental skin fibrosis of different aetiologies
-
C. Dees, C. Beyer, A. Distler, A. Soare, Y. Zhang, K. Palumbo-Zerr, O. Distler, G. Schett, P. Sandner, and J.H. Distler Stimulators of soluble guanylate cyclase (sGC) inhibit experimental skin fibrosis of different aetiologies Ann. Rheum. Dis. 2015 1621 1625
-
(2015)
Ann. Rheum. Dis.
, pp. 1621-1625
-
-
Dees, C.1
Beyer, C.2
Distler, A.3
Soare, A.4
Zhang, Y.5
Palumbo-Zerr, K.6
Distler, O.7
Schett, G.8
Sandner, P.9
Distler, J.H.10
-
17
-
-
79956122627
-
Platelet-derived serotonin links vascular disease and tissue fibrosis
-
C. Dees, A. Akhmetshina, P. Zerr, N. Reich, K. Palumbo, A. Horn, A. Jungel, C. Beyer, G. Kronke, J. Zwerina, R. Reiter, N. Alenina, L. Maroteaux, S. Gay, G. Schett, O. Distler, and J.H. Distler Platelet-derived serotonin links vascular disease and tissue fibrosis J. Exp. Med. 208 2011 961 972
-
(2011)
J. Exp. Med.
, vol.208
, pp. 961-972
-
-
Dees, C.1
Akhmetshina, A.2
Zerr, P.3
Reich, N.4
Palumbo, K.5
Horn, A.6
Jungel, A.7
Beyer, C.8
Kronke, G.9
Zwerina, J.10
Reiter, R.11
Alenina, N.12
Maroteaux, L.13
Gay, S.14
Schett, G.15
Distler, O.16
Distler, J.H.17
-
18
-
-
0028835189
-
Role of thrombin in pulmonary fibrosis
-
N.A. Hernandez-Rodriguez, A.D. Cambrey, N.K. Harrison, R.C. Chambers, A.J. Gray, A.M. Southcott, R.M. duBois, C.M. Black, M.F. Scully, R.J. McAnulty, and et al. Role of thrombin in pulmonary fibrosis Lancet 346 1995 1071 1073
-
(1995)
Lancet
, vol.346
, pp. 1071-1073
-
-
Hernandez-Rodriguez, N.A.1
Cambrey, A.D.2
Harrison, N.K.3
Chambers, R.C.4
Gray, A.J.5
Southcott, A.M.6
Dubois, R.M.7
Black, C.M.8
Scully, M.F.9
McAnulty, R.J.10
-
19
-
-
0023886092
-
Plasma free and intraplatelet serotonin in patients with Raynaud's phenomenon
-
M.L. Biondi, B. Marasini, E. Bianchi, and A. Agostoni Plasma free and intraplatelet serotonin in patients with Raynaud's phenomenon Int. J. Cardiol. 19 1988 335 339
-
(1988)
Int. J. Cardiol.
, vol.19
, pp. 335-339
-
-
Biondi, M.L.1
Marasini, B.2
Bianchi, E.3
Agostoni, A.4
-
20
-
-
33745277147
-
Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis
-
S.S. Baroni, M. Santillo, F. Bevilacqua, M. Luchetti, T. Spadoni, M. Mancini, P. Fraticelli, P. Sambo, A. Funaro, A. Kazlauskas, E.V. Avvedimento, and A. Gabrielli Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis N. Engl. J. Med. 354 2006 2667 2676
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 2667-2676
-
-
Baroni, S.S.1
Santillo, M.2
Bevilacqua, F.3
Luchetti, M.4
Spadoni, T.5
Mancini, M.6
Fraticelli, P.7
Sambo, P.8
Funaro, A.9
Kazlauskas, A.10
Avvedimento, E.V.11
Gabrielli, A.12
-
21
-
-
51349167276
-
Growth factors and cytokines in wound healing
-
S. Barrientos, O. Stojadinovic, M.S. Golinko, H. Brem, and M. Tomic-Canic Growth factors and cytokines in wound healing Wound Repair Regen. 16 2008 585 601
-
(2008)
Wound Repair Regen.
, vol.16
, pp. 585-601
-
-
Barrientos, S.1
Stojadinovic, O.2
Golinko, M.S.3
Brem, H.4
Tomic-Canic, M.5
-
22
-
-
80155206225
-
Imatinib in active diffuse cutaneous systemic sclerosis: results of a six-month, randomized, double-blind, placebo-controlled, proof-of-concept pilot study at a single center
-
J. Pope, D. McBain, L. Petrlich, S. Watson, L. Vanderhoek, F. de Leon, S. Seney, and K. Summers Imatinib in active diffuse cutaneous systemic sclerosis: results of a six-month, randomized, double-blind, placebo-controlled, proof-of-concept pilot study at a single center Arthritis Rheum. 63 2011 3547 3551
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 3547-3551
-
-
Pope, J.1
McBain, D.2
Petrlich, L.3
Watson, S.4
Vanderhoek, L.5
De Leon, F.6
Seney, S.7
Summers, K.8
-
23
-
-
79961031252
-
Overexpression of VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, leads to insufficient angiogenesis in patients with systemic sclerosis
-
M. Manetti, S. Guiducci, E. Romano, C. Ceccarelli, S. Bellando-Randone, M.L. Conforti, L. Ibba-Manneschi, and M. Matucci-Cerinic Overexpression of VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, leads to insufficient angiogenesis in patients with systemic sclerosis Circ. Res. 109 2011 e14 e26
-
(2011)
Circ. Res.
, vol.109
, pp. e14-e26
-
-
Manetti, M.1
Guiducci, S.2
Romano, E.3
Ceccarelli, C.4
Bellando-Randone, S.5
Conforti, M.L.6
Ibba-Manneschi, L.7
Matucci-Cerinic, M.8
-
24
-
-
84882464963
-
Vascular endothelial growth factor aggravates fibrosis and vasculopathy in experimental models of systemic sclerosis
-
B. Maurer, A. Distler, Y.A. Suliman, R.E. Gay, B.A. Michel, S. Gay, J.H. Distler, and O. Distler Vascular endothelial growth factor aggravates fibrosis and vasculopathy in experimental models of systemic sclerosis Ann. Rheum. Dis. 73 2014 1880 1887
-
(2014)
Ann. Rheum. Dis.
, vol.73
, pp. 1880-1887
-
-
Maurer, B.1
Distler, A.2
Suliman, Y.A.3
Gay, R.E.4
Michel, B.A.5
Gay, S.6
Distler, J.H.7
Distler, O.8
-
25
-
-
84930387053
-
Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis
-
J. Huang, C. Beyer, K. Palumbo-Zerr, Y. Zhang, A. Ramming, A. Distler, K. Gelse, O. Distler, G. Schett, L. Wollin, and J.H. Distler Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis Ann. Rheum. Dis. 2015 10.1136/annrheumdis-2014-207109
-
(2015)
Ann. Rheum. Dis.
-
-
Huang, J.1
Beyer, C.2
Palumbo-Zerr, K.3
Zhang, Y.4
Ramming, A.5
Distler, A.6
Gelse, K.7
Distler, O.8
Schett, G.9
Wollin, L.10
Distler, J.H.11
-
26
-
-
49649123154
-
BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy
-
F. Hilberg, G.J. Roth, M. Krssak, S. Kautschitsch, W. Sommergruber, U. Tontsch-Grunt, P. Garin-Chesa, G. Bader, A. Zoephel, J. Quant, A. Heckel, and W.J. Rettig BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy Cancer Res. 68 2008 4774 4782
-
(2008)
Cancer Res.
, vol.68
, pp. 4774-4782
-
-
Hilberg, F.1
Roth, G.J.2
Krssak, M.3
Kautschitsch, S.4
Sommergruber, W.5
Tontsch-Grunt, U.6
Garin-Chesa, P.7
Bader, G.8
Zoephel, A.9
Quant, J.10
Heckel, A.11
Rettig, W.J.12
-
27
-
-
84918842765
-
Combination therapy: the future of management for idiopathic pulmonary fibrosis?
-
W.A. Wuyts, K.M. Antoniou, K. Borensztajn, U. Costabel, V. Cottin, B. Crestani, J.C. Grutters, T.M. Maher, V. Poletti, L. Richeldi, C. Vancheri, and A.U. Wells Combination therapy: the future of management for idiopathic pulmonary fibrosis? Lancet Respir. Med. 2 2014 933 942
-
(2014)
Lancet Respir. Med.
, vol.2
, pp. 933-942
-
-
Wuyts, W.A.1
Antoniou, K.M.2
Borensztajn, K.3
Costabel, U.4
Cottin, V.5
Crestani, B.6
Grutters, J.C.7
Maher, T.M.8
Poletti, V.9
Richeldi, L.10
Vancheri, C.11
Wells, A.U.12
-
28
-
-
84924702197
-
Nintedanib: first global approval
-
P.L. McCormack Nintedanib: first global approval Drugs 75 2015 129 139
-
(2015)
Drugs
, vol.75
, pp. 129-139
-
-
McCormack, P.L.1
-
29
-
-
84860917655
-
Stimulation of soluble guanylate cyclase reduces experimental dermal fibrosis
-
C. Beyer, N. Reich, S.C. Schindler, A. Akhmetshina, C. Dees, M. Tomcik, C. Hirth-Dietrich, G. von Degenfeld, P. Sandner, O. Distler, G. Schett, and J.H. Distler Stimulation of soluble guanylate cyclase reduces experimental dermal fibrosis Ann. Rheum. Dis. 71 2012 1019 1026
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 1019-1026
-
-
Beyer, C.1
Reich, N.2
Schindler, S.C.3
Akhmetshina, A.4
Dees, C.5
Tomcik, M.6
Hirth-Dietrich, C.7
Von Degenfeld, G.8
Sandner, P.9
Distler, O.10
Schett, G.11
Distler, J.H.12
-
30
-
-
84880721470
-
Riociguat for the treatment of pulmonary arterial hypertension
-
H.A. Ghofrani, N. Galie, F. Grimminger, E. Grunig, M. Humbert, Z.C. Jing, A.M. Keogh, D. Langleben, M.O. Kilama, A. Fritsch, D. Neuser, and L.J. Rubin Riociguat for the treatment of pulmonary arterial hypertension N. Engl. J. Med. 369 2013 330 340
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 330-340
-
-
Ghofrani, H.A.1
Galie, N.2
Grimminger, F.3
Grunig, E.4
Humbert, M.5
Jing, Z.C.6
Keogh, A.M.7
Langleben, D.8
Kilama, M.O.9
Fritsch, A.10
Neuser, D.11
Rubin, L.J.12
-
31
-
-
70349572378
-
Alternatively activated macrophages (M2 macrophages) in the skin of patient with localized scleroderma
-
N. Higashi-Kuwata, T. Makino, Y. Inoue, M. Takeya, and H. Ihn Alternatively activated macrophages (M2 macrophages) in the skin of patient with localized scleroderma Exp. Dermatol. 18 2009 727 729
-
(2009)
Exp. Dermatol.
, vol.18
, pp. 727-729
-
-
Higashi-Kuwata, N.1
Makino, T.2
Inoue, Y.3
Takeya, M.4
Ihn, H.5
-
32
-
-
0041427695
-
Therapeutic attenuation of pulmonary fibrosis via targeting of IL-4- and IL-13-responsive cells
-
C. Jakubzick, E.S. Choi, B.H. Joshi, M.P. Keane, S.L. Kunkel, R.K. Puri, and C.M. Hogaboam Therapeutic attenuation of pulmonary fibrosis via targeting of IL-4- and IL-13-responsive cells J. Immunol. 171 2003 2684 2693
-
(2003)
J. Immunol.
, vol.171
, pp. 2684-2693
-
-
Jakubzick, C.1
Choi, E.S.2
Joshi, B.H.3
Keane, M.P.4
Kunkel, S.L.5
Puri, R.K.6
Hogaboam, C.M.7
-
33
-
-
0032697042
-
An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response
-
M.G. Chiaramonte, D.D. Donaldson, A.W. Cheever, and T.A. Wynn An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response J. Clin. Invest. 104 1999 777 785
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 777-785
-
-
Chiaramonte, M.G.1
Donaldson, D.D.2
Cheever, A.W.3
Wynn, T.A.4
-
34
-
-
84919866420
-
IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice
-
D. Li, R. Guabiraba, A.G. Besnard, M. Komai-Koma, M.S. Jabir, L. Zhang, G.J. Graham, M. Kurowska-Stolarska, F.Y. Liew, C. McSharry, and D. Xu IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice J. Allergy Clin. Immunol. 134 2014 1422-1432 e1411
-
(2014)
J. Allergy Clin. Immunol.
, vol.134
, pp. 1422-1432
-
-
Li, D.1
Guabiraba, R.2
Besnard, A.G.3
Komai-Koma, M.4
Jabir, M.S.5
Zhang, L.6
Graham, G.J.7
Kurowska-Stolarska, M.8
Liew, F.Y.9
McSharry, C.10
Xu, D.11
-
35
-
-
84882580383
-
Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis
-
T. McHedlidze, M. Waldner, S. Zopf, J. Walker, A.L. Rankin, M. Schuchmann, D. Voehringer, A.N. McKenzie, M.F. Neurath, S. Pflanz, and S. Wirtz Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis Immunity 39 2013 357 371
-
(2013)
Immunity
, vol.39
, pp. 357-371
-
-
McHedlidze, T.1
Waldner, M.2
Zopf, S.3
Walker, J.4
Rankin, A.L.5
Schuchmann, M.6
Voehringer, D.7
McKenzie, A.N.8
Neurath, M.F.9
Pflanz, S.10
Wirtz, S.11
-
36
-
-
79959580694
-
Serum IL-33 levels are raised in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosis
-
K. Yanaba, A. Yoshizaki, Y. Asano, T. Kadono, and S. Sato Serum IL-33 levels are raised in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosis Clin. Rheumatol. 30 2011 825 830
-
(2011)
Clin. Rheumatol.
, vol.30
, pp. 825-830
-
-
Yanaba, K.1
Yoshizaki, A.2
Asano, Y.3
Kadono, T.4
Sato, S.5
-
37
-
-
84890084669
-
Interleukin-33 potentiates bleomycin-induced lung injury
-
I.G. Luzina, P. Kopach, V. Lockatell, P.H. Kang, A. Nagarsekar, A.P. Burke, J.D. Hasday, N.W. Todd, and S.P. Atamas Interleukin-33 potentiates bleomycin-induced lung injury Am. J. Respir. Cell Mol. Biol. 49 2013 999 1008
-
(2013)
Am. J. Respir. Cell Mol. Biol.
, vol.49
, pp. 999-1008
-
-
Luzina, I.G.1
Kopach, P.2
Lockatell, V.3
Kang, P.H.4
Nagarsekar, A.5
Burke, A.P.6
Hasday, J.D.7
Todd, N.W.8
Atamas, S.P.9
-
38
-
-
84891943376
-
IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis
-
E. Hams, M.E. Armstrong, J.L. Barlow, S.P. Saunders, C. Schwartz, G. Cooke, R.J. Fahy, T.B. Crotty, N. Hirani, R.J. Flynn, D. Voehringer, A.N. McKenzie, S.C. Donnelly, and P.G. Fallon IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis Proc. Natl. Acad. Sci. U. S. A. 111 2014 367 372
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 367-372
-
-
Hams, E.1
Armstrong, M.E.2
Barlow, J.L.3
Saunders, S.P.4
Schwartz, C.5
Cooke, G.6
Fahy, R.J.7
Crotty, T.B.8
Hirani, N.9
Flynn, R.J.10
Voehringer, D.11
McKenzie, A.N.12
Donnelly, S.C.13
Fallon, P.G.14
-
39
-
-
84873721826
-
Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement
-
M.E. Truchetet, N.C. Brembilla, E. Montanari, P. Lonati, E. Raschi, S. Zeni, L. Fontao, P.L. Meroni, and C. Chizzolini Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement Arthritis Rheum. 65 2013 1347 1356
-
(2013)
Arthritis Rheum.
, vol.65
, pp. 1347-1356
-
-
Truchetet, M.E.1
Brembilla, N.C.2
Montanari, E.3
Lonati, P.4
Raschi, E.5
Zeni, S.6
Fontao, L.7
Meroni, P.L.8
Chizzolini, C.9
-
40
-
-
77949516122
-
Bleomycin and IL-1beta-mediated pulmonary fibrosis is IL-17A dependent
-
M.S. Wilson, S.K. Madala, T.R. Ramalingam, B.R. Gochuico, I.O. Rosas, A.W. Cheever, and T.A. Wynn Bleomycin and IL-1beta-mediated pulmonary fibrosis is IL-17A dependent J. Exp. Med. 207 2010 535 552
-
(2010)
J. Exp. Med.
, vol.207
, pp. 535-552
-
-
Wilson, M.S.1
Madala, S.K.2
Ramalingam, T.R.3
Gochuico, B.R.4
Rosas, I.O.5
Cheever, A.W.6
Wynn, T.A.7
-
41
-
-
84871922946
-
Differential role of regulatory T cells in early and late stages of pulmonary fibrosis
-
D. Boveda-Ruiz, C.N. D'Alessandro-Gabazza, M. Toda, T. Takagi, M. Naito, Y. Matsushima, T. Matsumoto, T. Kobayashi, P. Gil-Bernabe, A.L. Chelakkot-Govindalayathil, Y. Miyake, A. Yasukawa, J. Morser, O. Taguchi, and E.C. Gabazza Differential role of regulatory T cells in early and late stages of pulmonary fibrosis Immunobiology 218 2013 245 254
-
(2013)
Immunobiology
, vol.218
, pp. 245-254
-
-
Boveda-Ruiz, D.1
D'Alessandro-Gabazza, C.N.2
Toda, M.3
Takagi, T.4
Naito, M.5
Matsushima, Y.6
Matsumoto, T.7
Kobayashi, T.8
Gil-Bernabe, P.9
Chelakkot-Govindalayathil, A.L.10
Miyake, Y.11
Yasukawa, A.12
Morser, J.13
Taguchi, O.14
Gabazza, E.C.15
-
42
-
-
84920285641
-
IL-6 biology: implications for clinical targeting in rheumatic disease
-
L.H. Calabrese, and S. Rose-John IL-6 biology: implications for clinical targeting in rheumatic disease Nat. Rev. Rheumatol. 10 2014 720 727
-
(2014)
Nat. Rev. Rheumatol.
, vol.10
, pp. 720-727
-
-
Calabrese, L.H.1
Rose-John, S.2
-
43
-
-
0032746822
-
Enhanced production of interleukin-6 (IL-6), oncostatin M and soluble IL-6 receptor by cultured peripheral blood mononuclear cells from patients with systemic sclerosis
-
M. Hasegawa, S. Sato, H. Ihn, and K. Takehara Enhanced production of interleukin-6 (IL-6), oncostatin M and soluble IL-6 receptor by cultured peripheral blood mononuclear cells from patients with systemic sclerosis Rheumatology (Oxford) 38 1999 612 617
-
(1999)
Rheumatology (Oxford)
, vol.38
, pp. 612-617
-
-
Hasegawa, M.1
Sato, S.2
Ihn, H.3
Takehara, K.4
-
44
-
-
0034856397
-
Serum levels of interleukin-6 and interleukin-10 correlate with total skin thickness score in patients with systemic sclerosis
-
S. Sato, M. Hasegawa, and K. Takehara Serum levels of interleukin-6 and interleukin-10 correlate with total skin thickness score in patients with systemic sclerosis J. Dermatol. Sci. 27 2001 140 146
-
(2001)
J. Dermatol. Sci.
, vol.27
, pp. 140-146
-
-
Sato, S.1
Hasegawa, M.2
Takehara, K.3
-
45
-
-
33751541710
-
Mechanisms of disease: the role of immune cells in the pathogenesis of systemic sclerosis
-
L.I. Sakkas, I.C. Chikanza, and C.D. Platsoucas Mechanisms of disease: the role of immune cells in the pathogenesis of systemic sclerosis Nat. Clin. Pract. Rheumatol. 2 2006 679 685
-
(2006)
Nat. Clin. Pract. Rheumatol.
, vol.2
, pp. 679-685
-
-
Sakkas, L.I.1
Chikanza, I.C.2
Platsoucas, C.D.3
-
47
-
-
0027717313
-
In situ expression of cytokines and cellular adhesion molecules in the skin of patients with systemic sclerosis. Their role in early and late disease
-
A.E. Koch, L.B. Kronfeld-Harrington, Z. Szekanecz, M.M. Cho, G.K. Haines, L.A. Harlow, R.M. Strieter, S.L. Kunkel, M.C. Massa, W.G. Barr, and et al. In situ expression of cytokines and cellular adhesion molecules in the skin of patients with systemic sclerosis. Their role in early and late disease Pathobiology: J. Immunopathol. Mol. Cell. Biol. 61 1993 239 246
-
(1993)
Pathobiology: J. Immunopathol. Mol. Cell. Biol.
, vol.61
, pp. 239-246
-
-
Koch, A.E.1
Kronfeld-Harrington, L.B.2
Szekanecz, Z.3
Cho, M.M.4
Haines, G.K.5
Harlow, L.A.6
Strieter, R.M.7
Kunkel, S.L.8
Massa, M.C.9
Barr, W.G.10
-
49
-
-
34848833579
-
B cell infiltration in systemic sclerosis-associated interstitial lung disease
-
R. Lafyatis, C. O'Hara, C.A. Feghali-Bostwick, and E. Matteson B cell infiltration in systemic sclerosis-associated interstitial lung disease Arthritis Rheum. 56 2007 3167 3168
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 3167-3168
-
-
Lafyatis, R.1
O'Hara, C.2
Feghali-Bostwick, C.A.3
Matteson, E.4
-
50
-
-
0142059804
-
Systemic and cell type-specific gene expression patterns in scleroderma skin
-
M.L. Whitfield, D.R. Finlay, J.I. Murray, O.G. Troyanskaya, J.T. Chi, A. Pergamenschikov, T.H. McCalmont, P.O. Brown, D. Botstein, and M.K. Connolly Systemic and cell type-specific gene expression patterns in scleroderma skin Proc. Natl. Acad. Sci. U. S. A. 100 2003 12319 12324
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 12319-12324
-
-
Whitfield, M.L.1
Finlay, D.R.2
Murray, J.I.3
Troyanskaya, O.G.4
Chi, J.T.5
Pergamenschikov, A.6
McCalmont, T.H.7
Brown, P.O.8
Botstein, D.9
Connolly, M.K.10
-
51
-
-
84934991714
-
Effects and safety of rituximab in systemic sclerosis: an analysis from the European Scleroderma Trial and Research (EUSTAR) group
-
S. Jordan, J.H. Distler, B. Maurer, D. Huscher, J.M. van Laar, Y. Allanore, and O. Distler Effects and safety of rituximab in systemic sclerosis: an analysis from the European Scleroderma Trial and Research (EUSTAR) group Ann. Rheum. Dis. 74 2015 1188 1194
-
(2015)
Ann. Rheum. Dis.
, vol.74
, pp. 1188-1194
-
-
Jordan, S.1
Distler, J.H.2
Maurer, B.3
Huscher, D.4
Van Laar, J.M.5
Allanore, Y.6
Distler, O.7
-
52
-
-
84927176114
-
Transforming growth factor beta - at the centre of systemic sclerosis
-
R. Lafyatis Transforming growth factor beta - at the centre of systemic sclerosis Nat. Rev. Rheumatol. 10 2014 706 719
-
(2014)
Nat. Rev. Rheumatol.
, vol.10
, pp. 706-719
-
-
Lafyatis, R.1
-
53
-
-
33846250366
-
Recombinant human anti-transforming growth factor beta1 antibody therapy in systemic sclerosis: a multicenter, randomized, placebo-controlled phase I/II trial of CAT-192
-
C.P. Denton, P.A. Merkel, D.E. Furst, D. Khanna, P. Emery, V.M. Hsu, N. Silliman, J. Streisand, J. Powell, A. Akesson, J. Coppock, F. Hoogen, A. Herrick, M.D. Mayes, D. Veale, J. Haas, S. Ledbetter, J.H. Korn, C.M. Black, and J.R. Seibold Recombinant human anti-transforming growth factor beta1 antibody therapy in systemic sclerosis: a multicenter, randomized, placebo-controlled phase I/II trial of CAT-192 Arthritis Rheum. 56 2007 323 333
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 323-333
-
-
Denton, C.P.1
Merkel, P.A.2
Furst, D.E.3
Khanna, D.4
Emery, P.5
Hsu, V.M.6
Silliman, N.7
Streisand, J.8
Powell, J.9
Akesson, A.10
Coppock, J.11
Hoogen, F.12
Herrick, A.13
Mayes, M.D.14
Veale, D.15
Haas, J.16
Ledbetter, S.17
Korn, J.H.18
Black, C.M.19
Seibold, J.R.20
more..
-
54
-
-
84859247939
-
Innovative antifibrotic therapies in systemic sclerosis
-
C. Beyer, O. Distler, and J.H. Distler Innovative antifibrotic therapies in systemic sclerosis Curr. Opin. Rheumatol. 24 2012 274 280
-
(2012)
Curr. Opin. Rheumatol.
, vol.24
, pp. 274-280
-
-
Beyer, C.1
Distler, O.2
Distler, J.H.3
-
55
-
-
3543094383
-
Augmented production of transforming growth factor-beta by cultured peripheral blood mononuclear cells from patients with systemic sclerosis
-
M. Hasegawa, S. Sato, and K. Takehara Augmented production of transforming growth factor-beta by cultured peripheral blood mononuclear cells from patients with systemic sclerosis Arch. Dermatol. Res. 296 2004 89 93
-
(2004)
Arch. Dermatol. Res.
, vol.296
, pp. 89-93
-
-
Hasegawa, M.1
Sato, S.2
Takehara, K.3
-
56
-
-
0033524949
-
The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis
-
J.S. Munger, X. Huang, H. Kawakatsu, M.J. Griffiths, S.L. Dalton, J. Wu, J.F. Pittet, N. Kaminski, C. Garat, M.A. Matthay, D.B. Rifkin, and D. Sheppard The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis Cell 96 1999 319 328
-
(1999)
Cell
, vol.96
, pp. 319-328
-
-
Munger, J.S.1
Huang, X.2
Kawakatsu, H.3
Griffiths, M.J.4
Dalton, S.L.5
Wu, J.6
Pittet, J.F.7
Kaminski, N.8
Garat, C.9
Matthay, M.A.10
Rifkin, D.B.11
Sheppard, D.12
-
57
-
-
84889886646
-
Targeting of alphav integrin identifies a core molecular pathway that regulates fibrosis in several organs
-
N.C. Henderson, T.D. Arnold, Y. Katamura, M.M. Giacomini, J.D. Rodriguez, J.H. McCarty, A. Pellicoro, E. Raschperger, C. Betsholtz, P.G. Ruminski, D.W. Griggs, M.J. Prinsen, J.J. Maher, J.P. Iredale, A. Lacy-Hulbert, R.H. Adams, and D. Sheppard Targeting of alphav integrin identifies a core molecular pathway that regulates fibrosis in several organs Nat. Med. 19 2013 1617 1624
-
(2013)
Nat. Med.
, vol.19
, pp. 1617-1624
-
-
Henderson, N.C.1
Arnold, T.D.2
Katamura, Y.3
Giacomini, M.M.4
Rodriguez, J.D.5
McCarty, J.H.6
Pellicoro, A.7
Raschperger, E.8
Betsholtz, C.9
Ruminski, P.G.10
Griggs, D.W.11
Prinsen, M.J.12
Maher, J.J.13
Iredale, J.P.14
Lacy-Hulbert, A.15
Adams, R.H.16
Sheppard, D.17
-
58
-
-
84893081873
-
Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis
-
L. van Bon, A.J. Affandi, J. Broen, R.B. Christmann, R.J. Marijnissen, L. Stawski, G.A. Farina, G. Stifano, A.L. Mathes, M. Cossu, M. York, C. Collins, M. Wenink, R. Huijbens, R. Hesselstrand, T. Saxne, M. DiMarzio, D. Wuttge, S.K. Agarwal, J.D. Reveille, S. Assassi, M. Mayes, Y. Deng, J.P. Drenth, J. de Graaf, M. den Heijer, C.G. Kallenberg, M. Bijl, A. Loof, W.B. van den Berg, L.A. Joosten, V. Smith, F. de Keyser, R. Scorza, C. Lunardi, P.L. van Riel, M. Vonk, W. van Heerde, S. Meller, B. Homey, L. Beretta, M. Roest, M. Trojanowska, R. Lafyatis, and T.R. Radstake Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis N. Engl. J. Med. 370 2014 433 443
-
(2014)
N. Engl. J. Med.
, vol.370
, pp. 433-443
-
-
Van Bon, L.1
Affandi, A.J.2
Broen, J.3
Christmann, R.B.4
Marijnissen, R.J.5
Stawski, L.6
Farina, G.A.7
Stifano, G.8
Mathes, A.L.9
Cossu, M.10
York, M.11
Collins, C.12
Wenink, M.13
Huijbens, R.14
Hesselstrand, R.15
Saxne, T.16
Dimarzio, M.17
Wuttge, D.18
Agarwal, S.K.19
Reveille, J.D.20
Assassi, S.21
Mayes, M.22
Deng, Y.23
Drenth, J.P.24
De Graaf, J.25
Den Heijer, M.26
Kallenberg, C.G.27
Bijl, M.28
Loof, A.29
Van Den Berg, W.B.30
Joosten, L.A.31
Smith, V.32
De Keyser, F.33
Scorza, R.34
Lunardi, C.35
Van Riel, P.L.36
Vonk, M.37
Van Heerde, W.38
Meller, S.39
Homey, B.40
Beretta, L.41
Roest, M.42
Trojanowska, M.43
Lafyatis, R.44
Radstake, T.R.45
more..
-
59
-
-
84925537240
-
Orphan nuclear receptor NR4A1 regulates transforming growth factor-beta signaling and fibrosis
-
K. Palumbo-Zerr, P. Zerr, A. Distler, J. Fliehr, R. Mancuso, J. Huang, D. Mielenz, M. Tomcik, B.G. Furnrohr, C. Scholtysek, C. Dees, C. Beyer, G. Kronke, D. Metzger, O. Distler, G. Schett, and J.H. Distler Orphan nuclear receptor NR4A1 regulates transforming growth factor-beta signaling and fibrosis Nat. Med. 21 2015 150 158
-
(2015)
Nat. Med.
, vol.21
, pp. 150-158
-
-
Palumbo-Zerr, K.1
Zerr, P.2
Distler, A.3
Fliehr, J.4
Mancuso, R.5
Huang, J.6
Mielenz, D.7
Tomcik, M.8
Furnrohr, B.G.9
Scholtysek, C.10
Dees, C.11
Beyer, C.12
Kronke, G.13
Metzger, D.14
Distler, O.15
Schett, G.16
Distler, J.H.17
-
60
-
-
84934972568
-
Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages
-
C. Beyer, J. Huang, J. Beer, Y. Zhang, K. Palumbo-Zerr, P. Zerr, A. Distler, C. Dees, C. Maier, L. Munoz, G. Kronke, S. Uderhardt, O. Distler, S. Jones, S. Rose-John, T. Oravecz, G. Schett, and J.H. Distler Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages Ann. Rheum. Dis. 74 2015 1317 1324
-
(2015)
Ann. Rheum. Dis.
, vol.74
, pp. 1317-1324
-
-
Beyer, C.1
Huang, J.2
Beer, J.3
Zhang, Y.4
Palumbo-Zerr, K.5
Zerr, P.6
Distler, A.7
Dees, C.8
Maier, C.9
Munoz, L.10
Kronke, G.11
Uderhardt, S.12
Distler, O.13
Jones, S.14
Rose-John, S.15
Oravecz, T.16
Schett, G.17
Distler, J.H.18
-
61
-
-
84874412823
-
Activation of pregnane X receptor inhibits experimental dermal fibrosis
-
C. Beyer, A. Skapenko, A. Distler, C. Dees, H. Reichert, L. Munoz, J. Leipe, H. Schulze-Koops, O. Distler, G. Schett, and J.H. Distler Activation of pregnane X receptor inhibits experimental dermal fibrosis Ann. Rheum. Dis. 72 2013 621 625
-
(2013)
Ann. Rheum. Dis.
, vol.72
, pp. 621-625
-
-
Beyer, C.1
Skapenko, A.2
Distler, A.3
Dees, C.4
Reichert, H.5
Munoz, L.6
Leipe, J.7
Schulze-Koops, H.8
Distler, O.9
Schett, G.10
Distler, J.H.11
-
62
-
-
45849149234
-
PPAR-gamma agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis
-
J.E. Milam, V.G. Keshamouni, S.H. Phan, B. Hu, S.R. Gangireddy, C.M. Hogaboam, T.J. Standiford, V.J. Thannickal, and R.C. Reddy PPAR-gamma agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis Am. J. Physiol. Lung Cell. Mol. Physiol. 294 2008 L891 L901
-
(2008)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.294
, pp. L891-L901
-
-
Milam, J.E.1
Keshamouni, V.G.2
Phan, S.H.3
Hu, B.4
Gangireddy, S.R.5
Hogaboam, C.M.6
Standiford, T.J.7
Thannickal, V.J.8
Reddy, R.C.9
-
63
-
-
79951713169
-
Cooperative interaction of CTGF and TGF-beta in animal models of fibrotic disease
-
Q. Wang, W. Usinger, B. Nichols, J. Gray, L. Xu, T.W. Seeley, M. Brenner, G. Guo, W. Zhang, N. Oliver, A. Lin, and D. Yeowell Cooperative interaction of CTGF and TGF-beta in animal models of fibrotic disease Fibrogenesis Tissue Repair 4 2011 4
-
(2011)
Fibrogenesis Tissue Repair
, vol.4
, pp. 4
-
-
Wang, Q.1
Usinger, W.2
Nichols, B.3
Gray, J.4
Xu, L.5
Seeley, T.W.6
Brenner, M.7
Guo, G.8
Zhang, W.9
Oliver, N.10
Lin, A.11
Yeowell, D.12
-
64
-
-
84875779325
-
CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis
-
K.E. Lipson, C. Wong, Y. Teng, and S. Spong CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis Fibrogenesis Tissue Repair 5 2012 S24
-
(2012)
Fibrogenesis Tissue Repair
, vol.5
, pp. S24
-
-
Lipson, K.E.1
Wong, C.2
Teng, Y.3
Spong, S.4
-
65
-
-
38049091636
-
The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak
-
A.M. Tager, P. LaCamera, B.S. Shea, G.S. Campanella, M. Selman, Z. Zhao, V. Polosukhin, J. Wain, B.A. Karimi-Shah, N.D. Kim, W.K. Hart, A. Pardo, T.S. Blackwell, Y. Xu, J. Chun, and A.D. Luster The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak Nat. Med. 14 2008 45 54
-
(2008)
Nat. Med.
, vol.14
, pp. 45-54
-
-
Tager, A.M.1
Lacamera, P.2
Shea, B.S.3
Campanella, G.S.4
Selman, M.5
Zhao, Z.6
Polosukhin, V.7
Wain, J.8
Karimi-Shah, B.A.9
Kim, N.D.10
Hart, W.K.11
Pardo, A.12
Blackwell, T.S.13
Xu, Y.14
Chun, J.15
Luster, A.D.16
-
66
-
-
84859179083
-
Activation of canonical Wnt signalling is required for TGF-beta-mediated fibrosis
-
A. Akhmetshina, K. Palumbo, C. Dees, C. Bergmann, P. Venalis, P. Zerr, A. Horn, T. Kireva, C. Beyer, J. Zwerina, H. Schneider, A. Sadowski, M.O. Riener, O.A. MacDougald, O. Distler, G. Schett, and J.H. Distler Activation of canonical Wnt signalling is required for TGF-beta-mediated fibrosis Nat. Commun. 3 2012 735
-
(2012)
Nat. Commun.
, vol.3
, pp. 735
-
-
Akhmetshina, A.1
Palumbo, K.2
Dees, C.3
Bergmann, C.4
Venalis, P.5
Zerr, P.6
Horn, A.7
Kireva, T.8
Beyer, C.9
Zwerina, J.10
Schneider, H.11
Sadowski, A.12
Riener, M.O.13
MacDougald, O.A.14
Distler, O.15
Schett, G.16
Distler, J.H.17
-
67
-
-
65249134946
-
Wnt/beta-catenin signaling promotes renal interstitial fibrosis
-
W. He, C. Dai, Y. Li, G. Zeng, S.P. Monga, and Y. Liu Wnt/beta-catenin signaling promotes renal interstitial fibrosis J. Am. Soc. Nephrol. 20 2009 765 776
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 765-776
-
-
He, W.1
Dai, C.2
Li, Y.3
Zeng, G.4
Monga, S.P.5
Liu, Y.6
-
68
-
-
58149333154
-
Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction
-
K. Kobayashi, M. Luo, Y. Zhang, D.C. Wilkes, G. Ge, T. Grieskamp, C. Yamada, T.C. Liu, G. Huang, C.T. Basson, A. Kispert, D.S. Greenspan, and T.N. Sato Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction Nat. Cell Biol. 11 2009 46 55
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 46-55
-
-
Kobayashi, K.1
Luo, M.2
Zhang, Y.3
Wilkes, D.C.4
Ge, G.5
Grieskamp, T.6
Yamada, C.7
Liu, T.C.8
Huang, G.9
Basson, C.T.10
Kispert, A.11
Greenspan, D.S.12
Sato, T.N.13
-
69
-
-
65249088418
-
WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis
-
M. Konigshoff, M. Kramer, N. Balsara, J. Wilhelm, O.V. Amarie, A. Jahn, F. Rose, L. Fink, W. Seeger, L. Schaefer, A. Gunther, and O. Eickelberg WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis J. Clin. Invest. 119 2009 772 787
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 772-787
-
-
Konigshoff, M.1
Kramer, M.2
Balsara, N.3
Wilhelm, J.4
Amarie, O.V.5
Jahn, A.6
Rose, F.7
Fink, L.8
Seeger, W.9
Schaefer, L.10
Gunther, A.11
Eickelberg, O.12
-
70
-
-
79958077377
-
Nuclear beta-catenin is increased in systemic sclerosis pulmonary fibrosis and promotes lung fibroblast migration and proliferation
-
A.P. Lam, A.S. Flozak, S. Russell, J. Wei, M. Jain, G.M. Mutlu, G.R. Budinger, C.A. Feghali-Bostwick, J. Varga, and C.J. Gottardi Nuclear beta-catenin is increased in systemic sclerosis pulmonary fibrosis and promotes lung fibroblast migration and proliferation Am. J. Respir. Cell Mol. Biol. 45 2011 915 922
-
(2011)
Am. J. Respir. Cell Mol. Biol.
, vol.45
, pp. 915-922
-
-
Lam, A.P.1
Flozak, A.S.2
Russell, S.3
Wei, J.4
Jain, M.5
Mutlu, G.M.6
Budinger, G.R.7
Feghali-Bostwick, C.A.8
Varga, J.9
Gottardi, C.J.10
-
71
-
-
33746513742
-
Upregulation of the Wnt/beta-catenin pathway induced by transforming growth factor-beta in hypertrophic scars and keloids
-
M. Sato Upregulation of the Wnt/beta-catenin pathway induced by transforming growth factor-beta in hypertrophic scars and keloids Acta Derm. Venereol. 86 2006 300 307
-
(2006)
Acta Derm. Venereol.
, vol.86
, pp. 300-307
-
-
Sato, M.1
-
72
-
-
28444468088
-
Wnt-dependent beta-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis
-
K. Surendran, S. Schiavi, and K.A. Hruska Wnt-dependent beta-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis J. Am. Soc. Nephrol. 16 2005 2373 2384
-
(2005)
J. Am. Soc. Nephrol.
, vol.16
, pp. 2373-2384
-
-
Surendran, K.1
Schiavi, S.2
Hruska, K.A.3
-
73
-
-
84863133508
-
Axin pathway activity regulates in vivo pY654-beta-catenin accumulation and pulmonary fibrosis
-
A. Ulsamer, Y. Wei, K.K. Kim, K. Tan, S. Wheeler, Y. Xi, R.S. Thies, and H.A. Chapman Axin pathway activity regulates in vivo pY654-beta-catenin accumulation and pulmonary fibrosis J. Biol. Chem. 287 2012 5164 5172
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 5164-5172
-
-
Ulsamer, A.1
Wei, Y.2
Kim, K.K.3
Tan, K.4
Wheeler, S.5
Xi, Y.6
Thies, R.S.7
Chapman, H.A.8
-
74
-
-
84863923526
-
Wnt/beta-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells
-
J. Wei, F. Fang, A.P. Lam, J.L. Sargent, E. Hamburg, M.E. Hinchcliff, C.J. Gottardi, R. Atit, M.L. Whitfield, and J. Varga Wnt/beta-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells Arthritis Rheum. 64 2012 2734 2745
-
(2012)
Arthritis Rheum.
, vol.64
, pp. 2734-2745
-
-
Wei, J.1
Fang, F.2
Lam, A.P.3
Sargent, J.L.4
Hamburg, E.5
Hinchcliff, M.E.6
Gottardi, C.J.7
Atit, R.8
Whitfield, M.L.9
Varga, J.10
-
75
-
-
79958036406
-
Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma?
-
J. Wei, D. Melichian, K. Komura, M. Hinchcliff, A.P. Lam, R. Lafyatis, C.J. Gottardi, O.A. MacDougald, and J. Varga Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma? Arthritis Rheum. 63 2011 1707 1717
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 1707-1717
-
-
Wei, J.1
Melichian, D.2
Komura, K.3
Hinchcliff, M.4
Lam, A.P.5
Lafyatis, R.6
Gottardi, C.J.7
MacDougald, O.A.8
Varga, J.9
-
77
-
-
40649105572
-
Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis
-
J. Bayle, J. Fitch, K. Jacobsen, R. Kumar, R. Lafyatis, and R. Lemaire Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis J. Invest. Dermatol. 128 2008 871 881
-
(2008)
J. Invest. Dermatol.
, vol.128
, pp. 871-881
-
-
Bayle, J.1
Fitch, J.2
Jacobsen, K.3
Kumar, R.4
Lafyatis, R.5
Lemaire, R.6
-
78
-
-
82755197822
-
Inhibition of glycogen synthase kinase 3beta induces dermal fibrosis by activation of the canonical Wnt pathway
-
C. Bergmann, A. Akhmetshina, C. Dees, K. Palumbo, P. Zerr, C. Beyer, J. Zwerina, O. Distler, G. Schett, and J.H. Distler Inhibition of glycogen synthase kinase 3beta induces dermal fibrosis by activation of the canonical Wnt pathway Ann. Rheum. Dis. 70 2011 2191 2198
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 2191-2198
-
-
Bergmann, C.1
Akhmetshina, A.2
Dees, C.3
Palumbo, K.4
Zerr, P.5
Beyer, C.6
Zwerina, J.7
Distler, O.8
Schett, G.9
Distler, J.H.10
-
79
-
-
84859500585
-
Beta-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis
-
C. Beyer, A. Schramm, A. Akhmetshina, C. Dees, T. Kireva, K. Gelse, S. Sonnylal, B. de Crombrugghe, M.M. Taketo, O. Distler, G. Schett, and J.H. Distler Beta-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis Ann. Rheum. Dis. 71 2012 761 767
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 761-767
-
-
Beyer, C.1
Schramm, A.2
Akhmetshina, A.3
Dees, C.4
Kireva, T.5
Gelse, K.6
Sonnylal, S.7
De Crombrugghe, B.8
Taketo, M.M.9
Distler, O.10
Schett, G.11
Distler, J.H.12
-
80
-
-
84866393033
-
Sustained beta-catenin activity in dermal fibroblasts is sufficient for skin fibrosis
-
E.J. Hamburg, and R.P. Atit Sustained beta-catenin activity in dermal fibroblasts is sufficient for skin fibrosis J. Invest. Dermatol. 132 2012 2469 2472
-
(2012)
J. Invest. Dermatol.
, vol.132
, pp. 2469-2472
-
-
Hamburg, E.J.1
Atit, R.P.2
-
81
-
-
84862170024
-
Drugging Wnt signalling in cancer
-
P. Polakis Drugging Wnt signalling in cancer EMBO J. 31 2012 2737 2746
-
(2012)
EMBO J.
, vol.31
, pp. 2737-2746
-
-
Polakis, P.1
-
82
-
-
84881480768
-
Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling
-
A. Distler, L. Deloch, J. Huang, C. Dees, N.Y. Lin, K. Palumbo-Zerr, C. Beyer, A. Weidemann, O. Distler, G. Schett, and J.H. Distler Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling Ann. Rheum. Dis. 72 2013 1575 1580
-
(2013)
Ann. Rheum. Dis.
, vol.72
, pp. 1575-1580
-
-
Distler, A.1
Deloch, L.2
Huang, J.3
Dees, C.4
Lin, N.Y.5
Palumbo-Zerr, K.6
Beyer, C.7
Weidemann, A.8
Distler, O.9
Schett, G.10
Distler, J.H.11
-
83
-
-
84878406860
-
Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis
-
C. Beyer, H. Reichert, H. Akan, T. Mallano, A. Schramm, C. Dees, K. Palumbo-Zerr, N.Y. Lin, A. Distler, K. Gelse, J. Varga, O. Distler, G. Schett, and J.H. Distler Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis Ann. Rheum. Dis. 72 2013 1255 1258
-
(2013)
Ann. Rheum. Dis.
, vol.72
, pp. 1255-1258
-
-
Beyer, C.1
Reichert, H.2
Akan, H.3
Mallano, T.4
Schramm, A.5
Dees, C.6
Palumbo-Zerr, K.7
Lin, N.Y.8
Distler, A.9
Gelse, K.10
Varga, J.11
Distler, O.12
Schett, G.13
Distler, J.H.14
-
84
-
-
84899914231
-
The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis
-
C. Dees, I. Schlottmann, R. Funke, A. Distler, K. Palumbo-Zerr, P. Zerr, N.Y. Lin, C. Beyer, O. Distler, G. Schett, and J.H. Distler The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis Ann. Rheum. Dis. 73 2014 1232 1239
-
(2014)
Ann. Rheum. Dis.
, vol.73
, pp. 1232-1239
-
-
Dees, C.1
Schlottmann, I.2
Funke, R.3
Distler, A.4
Palumbo-Zerr, K.5
Zerr, P.6
Lin, N.Y.7
Beyer, C.8
Distler, O.9
Schett, G.10
Distler, J.H.11
-
85
-
-
33646071894
-
Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study
-
H. Kantarjian, J.P. Issa, C.S. Rosenfeld, J.M. Bennett, M. Albitar, J. DiPersio, V. Klimek, J. Slack, C. de Castro, F. Ravandi, R. Helmer 3rd, L. Shen, S.D. Nimer, R. Leavitt, A. Raza, and H. Saba Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study Cancer 106 2006 1794 1803
-
(2006)
Cancer
, vol.106
, pp. 1794-1803
-
-
Kantarjian, H.1
Issa, J.P.2
Rosenfeld, C.S.3
Bennett, J.M.4
Albitar, M.5
Dipersio, J.6
Klimek, V.7
Slack, J.8
De Castro, C.9
Ravandi, F.10
Helmer, R.11
Shen, L.12
Nimer, S.D.13
Leavitt, R.14
Raza, A.15
Saba, H.16
-
86
-
-
33846011361
-
Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia
-
H. Kantarjian, Y. Oki, G. Garcia-Manero, X. Huang, S. O'Brien, J. Cortes, S. Faderl, C. Bueso-Ramos, F. Ravandi, Z. Estrov, A. Ferrajoli, W. Wierda, J. Shan, J. Davis, F. Giles, H.I. Saba, and J.P. Issa Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia Blood 109 2007 52 57
-
(2007)
Blood
, vol.109
, pp. 52-57
-
-
Kantarjian, H.1
Oki, Y.2
Garcia-Manero, G.3
Huang, X.4
O'Brien, S.5
Cortes, J.6
Faderl, S.7
Bueso-Ramos, C.8
Ravandi, F.9
Estrov, Z.10
Ferrajoli, A.11
Wierda, W.12
Shan, J.13
Davis, J.14
Giles, F.15
Saba, H.I.16
Issa, J.P.17
-
87
-
-
34248329903
-
Review: recent clinical trials in epigenetic therapy
-
Y. Oki, and J.P. Issa Review: recent clinical trials in epigenetic therapy Rev. Recent Clin. Trials 1 2006 169 182
-
(2006)
Rev. Recent Clin. Trials
, vol.1
, pp. 169-182
-
-
Oki, Y.1
Issa, J.P.2
-
88
-
-
79956308325
-
Mechanisms and functions of Hedgehog signalling across the metazoa
-
P.W. Ingham, Y. Nakano, and C. Seger Mechanisms and functions of Hedgehog signalling across the metazoa Nat. Rev. Genet. 12 2011 393 406
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 393-406
-
-
Ingham, P.W.1
Nakano, Y.2
Seger, C.3
-
89
-
-
84859503196
-
Inhibition of hedgehog signalling prevents experimental fibrosis and induces regression of established fibrosis
-
A. Horn, T. Kireva, K. Palumbo-Zerr, C. Dees, M. Tomcik, C. Cordazzo, P. Zerr, A. Akhmetshina, M. Ruat, O. Distler, C. Beyer, G. Schett, and J.H. Distler Inhibition of hedgehog signalling prevents experimental fibrosis and induces regression of established fibrosis Ann. Rheum. Dis. 71 2012 785 789
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 785-789
-
-
Horn, A.1
Kireva, T.2
Palumbo-Zerr, K.3
Dees, C.4
Tomcik, M.5
Cordazzo, C.6
Zerr, P.7
Akhmetshina, A.8
Ruat, M.9
Distler, O.10
Beyer, C.11
Schett, G.12
Distler, J.H.13
-
90
-
-
84859260199
-
Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis
-
A. Horn, K. Palumbo, C. Cordazzo, C. Dees, A. Akhmetshina, M. Tomcik, P. Zerr, J. Avouac, J. Gusinde, J. Zwerina, H. Roudaut, E. Traiffort, M. Ruat, O. Distler, G. Schett, and J.H. Distler Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis Arthritis Rheum. 64 2012 2724 2733
-
(2012)
Arthritis Rheum.
, vol.64
, pp. 2724-2733
-
-
Horn, A.1
Palumbo, K.2
Cordazzo, C.3
Dees, C.4
Akhmetshina, A.5
Tomcik, M.6
Zerr, P.7
Avouac, J.8
Gusinde, J.9
Zwerina, J.10
Roudaut, H.11
Traiffort, E.12
Ruat, M.13
Distler, O.14
Schett, G.15
Distler, J.H.16
-
91
-
-
84867254044
-
Inhibition of hedgehog signaling for the treatment of murine sclerodermatous chronic graft-versus-host disease
-
P. Zerr, K. Palumbo-Zerr, A. Distler, M. Tomcik, S. Vollath, L.E. Munoz, C. Beyer, C. Dees, F. Egberts, I. Tinazzi, F. Del Galdo, O. Distler, G. Schett, B.M. Spriewald, and J.H. Distler Inhibition of hedgehog signaling for the treatment of murine sclerodermatous chronic graft-versus-host disease Blood 120 2012 2909 2917
-
(2012)
Blood
, vol.120
, pp. 2909-2917
-
-
Zerr, P.1
Palumbo-Zerr, K.2
Distler, A.3
Tomcik, M.4
Vollath, S.5
Munoz, L.E.6
Beyer, C.7
Dees, C.8
Egberts, F.9
Tinazzi, I.10
Del Galdo, F.11
Distler, O.12
Schett, G.13
Spriewald, B.M.14
Distler, J.H.15
-
92
-
-
65549121943
-
Notch signaling: the core pathway and its posttranslational regulation
-
M.E. Fortini Notch signaling: the core pathway and its posttranslational regulation Dev. Cell 16 2009 633 647
-
(2009)
Dev. Cell
, vol.16
, pp. 633-647
-
-
Fortini, M.E.1
-
93
-
-
78049449123
-
Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans
-
B. Bielesz, Y. Sirin, H. Si, T. Niranjan, A. Gruenwald, S. Ahn, H. Kato, J. Pullman, M. Gessler, V.H. Haase, and K. Susztak Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans J. Clin. Invest. 120 2010 4040 4054
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 4040-4054
-
-
Bielesz, B.1
Sirin, Y.2
Si, H.3
Niranjan, T.4
Gruenwald, A.5
Ahn, S.6
Kato, H.7
Pullman, J.8
Gessler, M.9
Haase, V.H.10
Susztak, K.11
-
94
-
-
79957637197
-
Notch signalling regulates fibroblast activation and collagen release in systemic sclerosis
-
C. Dees, M. Tomcik, P. Zerr, A. Akhmetshina, A. Horn, K. Palumbo, C. Beyer, J. Zwerina, O. Distler, G. Schett, and J.H. Distler Notch signalling regulates fibroblast activation and collagen release in systemic sclerosis Ann. Rheum. Dis. 70 2011 1304 1310
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 1304-1310
-
-
Dees, C.1
Tomcik, M.2
Zerr, P.3
Akhmetshina, A.4
Horn, A.5
Palumbo, K.6
Beyer, C.7
Zwerina, J.8
Distler, O.9
Schett, G.10
Distler, J.H.11
-
95
-
-
78249268282
-
Targeting ADAM-17/notch signaling abrogates the development of systemic sclerosis in a murine model
-
N. Kavian, A. Servettaz, C. Mongaret, A. Wang, C. Nicco, C. Chereau, P. Grange, V. Vuiblet, P. Birembaut, M.D. Diebold, B. Weill, N. Dupin, and F. Batteux Targeting ADAM-17/notch signaling abrogates the development of systemic sclerosis in a murine model Arthritis Rheum. 62 2010 3477 3487
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 3477-3487
-
-
Kavian, N.1
Servettaz, A.2
Mongaret, C.3
Wang, A.4
Nicco, C.5
Chereau, C.6
Grange, P.7
Vuiblet, V.8
Birembaut, P.9
Diebold, M.D.10
Weill, B.11
Dupin, N.12
Batteux, F.13
-
96
-
-
79955567838
-
Inhibition of Notch signaling prevents experimental fibrosis and induces regression of established fibrosis
-
C. Dees, P. Zerr, M. Tomcik, C. Beyer, A. Horn, A. Akhmetshina, K. Palumbo, N. Reich, J. Zwerina, M. Sticherling, M.P. Mattson, O. Distler, G. Schett, and J.H. Distler Inhibition of Notch signaling prevents experimental fibrosis and induces regression of established fibrosis Arthritis Rheum. 63 2011 1396 1404
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 1396-1404
-
-
Dees, C.1
Zerr, P.2
Tomcik, M.3
Beyer, C.4
Horn, A.5
Akhmetshina, A.6
Palumbo, K.7
Reich, N.8
Zwerina, J.9
Sticherling, M.10
Mattson, M.P.11
Distler, O.12
Schett, G.13
Distler, J.H.14
-
97
-
-
84899626029
-
Therapeutic modulation of Notch signalling - are we there yet?
-
E.R. Andersson, and U. Lendahl Therapeutic modulation of Notch signalling - are we there yet? Nat. Rev. Drug Discov. 13 2014 357 378
-
(2014)
Nat. Rev. Drug Discov.
, vol.13
, pp. 357-378
-
-
Andersson, E.R.1
Lendahl, U.2
-
98
-
-
84861968011
-
Therapeutic approaches to modulating Notch signaling: current challenges and future prospects
-
C. Groth, and M.E. Fortini Therapeutic approaches to modulating Notch signaling: current challenges and future prospects Semin. Cell Dev. Biol. 23 2012 465 472
-
(2012)
Semin. Cell Dev. Biol.
, vol.23
, pp. 465-472
-
-
Groth, C.1
Fortini, M.E.2
-
99
-
-
0242412482
-
Adipsin, a biomarker of gastrointestinal toxicity mediated by a functional gamma-secretase inhibitor
-
G.H. Searfoss, W.H. Jordan, D.O. Calligaro, E.J. Galbreath, L.M. Schirtzinger, B.R. Berridge, H. Gao, M.A. Higgins, P.C. May, and T.P. Ryan Adipsin, a biomarker of gastrointestinal toxicity mediated by a functional gamma-secretase inhibitor J. Biol. Chem. 278 2003 46107 46116
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 46107-46116
-
-
Searfoss, G.H.1
Jordan, W.H.2
Calligaro, D.O.3
Galbreath, E.J.4
Schirtzinger, L.M.5
Berridge, B.R.6
Gao, H.7
Higgins, M.A.8
May, P.C.9
Ryan, T.P.10
-
100
-
-
20544460148
-
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
-
J.H. van Es, M.E. van Gijn, O. Riccio, M. van den Born, M. Vooijs, H. Begthel, M. Cozijnsen, S. Robine, D.J. Winton, F. Radtke, and H. Clevers Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells Nature 435 2005 959 963
-
(2005)
Nature
, vol.435
, pp. 959-963
-
-
Van Es, J.H.1
Van Gijn, M.E.2
Riccio, O.3
Van Den Born, M.4
Vooijs, M.5
Begthel, H.6
Cozijnsen, M.7
Robine, S.8
Winton, D.J.9
Radtke, F.10
Clevers, H.11
-
101
-
-
77955331793
-
Cellular and molecular aspects of vascular dysfunction in systemic sclerosis
-
M. Trojanowska Cellular and molecular aspects of vascular dysfunction in systemic sclerosis Nat. Rev. Rheumatol. 6 2010 453 460
-
(2010)
Nat. Rev. Rheumatol.
, vol.6
, pp. 453-460
-
-
Trojanowska, M.1
-
102
-
-
77952946050
-
MicroRNA-29, a key regulator of collagen expression in systemic sclerosis
-
B. Maurer, J. Stanczyk, A. Jungel, A. Akhmetshina, M. Trenkmann, M. Brock, O. Kowal-Bielecka, R.E. Gay, B.A. Michel, J.H. Distler, S. Gay, and O. Distler MicroRNA-29, a key regulator of collagen expression in systemic sclerosis Arthritis Rheum. 62 2010 1733 1743
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 1733-1743
-
-
Maurer, B.1
Stanczyk, J.2
Jungel, A.3
Akhmetshina, A.4
Trenkmann, M.5
Brock, M.6
Kowal-Bielecka, O.7
Gay, R.E.8
Michel, B.A.9
Distler, J.H.10
Gay, S.11
Distler, O.12
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