Transient activation of microglia following acute alcohol exposure in developing mouse neocortex is primarily driven by BAX-dependent neurodegeneration

GLIA

Volumn 63, Issue 10, 2015, Pages 1694-1713

  Ahlers, Katelin E ^a   Karaçay, Bahri ^b   Fuller, Leah ^a   Bonthius, Daniel J ^b   Dailey, Michael E ^a  

^a University of Iowa   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Apoptosis; Development; Fetal alcohol spectrum disorders; Phagocytosis

Indexed keywords

ALCOHOL; INTERLEUKIN 1BETA; PROTEIN BAX; TUMOR NECROSIS FACTOR ALPHA; CASPASE 3; CD18 ANTIGEN; CENTRAL DEPRESSANT AGENT; CHEMOKINE RECEPTOR; CX3CR1 PROTEIN, MOUSE; CYTOKINE; P2RY12 PROTEIN, MOUSE; PEPTIDE; PREIMPLANTATION FACTOR, MOUSE; PURINERGIC P2Y12 RECEPTOR;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; CELL DEATH; CONTROLLED STUDY; FEMALE; IN VIVO STUDY; MALE; MICROGLIA; MOUSE; NEOCORTEX; NERVE DEGENERATION; NONHUMAN; PERINATAL PERIOD; PRENATAL EXPOSURE; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; CELL COUNT; CHEMICALLY INDUCED; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; NEWBORN; PATHOLOGY; TIME FACTOR; TRANSGENIC MOUSE;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD18; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL COUNT; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CYTOKINES; ETHANOL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; NEOCORTEX; NERVE DEGENERATION; PEPTIDES; RECEPTORS, CHEMOKINE; RECEPTORS, PURINERGIC P2Y12; TIME FACTORS;

EID: 84938956046     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22835     Document Type: Article

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