An epistatic interaction between Themis1 and Vav1 modulates regulatory T cell function and inflammatory bowel disease development

Journal of Immunology

Volumn 195, Issue 4, 2015, Pages 1608-1616

  Pedros, Christophe ^a,b,c   Gaud, Guillaume ^a,b,c   Bernard, Isabelle ^a,b,c   Kassem, Sahar ^a,b,c   Chabod, Marianne ^a,b,c   Lagrange, Dominique ^a,b,c   Andréoletti, Olivier ^d   Dejean, Anne S ^a,b,c   Lesourne, Renaud ^a,b,c   Fournié, Gilbert J ^a,b,c   Saoudi, Abdelhadi ^a,b,c  

^a INSERM   (France)

^b CNRS   (France)

^c UNIVERSITÉ PAUL SABATIER   (France)

^d UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; CYTOKINE; LYMPHOCYTE ANTIGEN RECEPTOR; SIGNAL PEPTIDE; THEMIS1 PROTEIN, RAT; VAV PROTEIN; VAV1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN NORWAY RAT; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENZYME ACTIVATION; EPISTASIS; FEMALE; GENE FUNCTION; GENE INTERACTION; GENETIC CODE; GENETIC POLYMORPHISM; GENETIC STABILITY; GENETIC VARIABILITY; INFLAMMATORY BOWEL DISEASE; LEWIS RAT; LYMPHOCYTE FUNCTION; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; STRAIN DIFFERENCE; THEMIS1 GENE; VAV1 GENE; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; GENETICS; IMMUNOLOGY; INTESTINE MUCOSA; METABOLISM; MUTATION; PATHOLOGY; T LYMPHOCYTE SUBPOPULATION; THYMOCYTE; TRANSGENIC RAT;

ANIMALS; CYTOKINES; DISEASE MODELS, ANIMAL; EPISTASIS, GENETIC; FEMALE; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MUTATION; PROTO-ONCOGENE PROTEINS C-VAV; RATS; RATS, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; THYMOCYTES;

EID: 84938912890     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402562     Document Type: Article

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