SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation

PLoS Genetics

Volumn 11, Issue 7, 2015, Pages

  Hu, Siqi ^a   Li, Jian ^a   Xu, Fengwen ^a   Mei, Shan ^a   Le Duff, Yann ^b   Yin, Lijuan ^a   Pang, Xiaojing ^a   Cen, Shan ^c   Jin, Qi ^a   Liang, Chen ^b   Guo, Fei ^a  

^a INSTITUTE OF PATHOGEN BIOLOGY   (China)

^b MCGILL UNIVERSITY   (Canada)

^c INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; G3BP1 PROTEIN; LONG INTERSPERSED ELEMENT 1; ORF1 PROTEIN; SAMHD1 PROTEIN; TIA 1 PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; EIF2AK1 PROTEIN, HUMAN; EIF4G1 PROTEIN, HUMAN; G3BP PROTEIN, HUMAN; INITIATION FACTOR 4G; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; POLYADENYLIC ACID BINDING PROTEIN; PROTEIN KINASE R; SAMHD1 PROTEIN, HUMAN; SMALL INTERFERING RNA; TIA1 PROTEIN, HUMAN;

ARTICLE; CELL COUNT; CELL GRANULE; CELL SIZE; CELL STRESS; CELLULAR PARAMETERS; CONTROLLED STUDY; CORRELATIONAL STUDY; CYTOPLASM; EMBRYO; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INHIBITION KINETICS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN RETROTRANSPOSITION; SIGNAL TRANSDUCTION; STRESS GRANULE FORMATION; CELL LINE; CELL PROLIFERATION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; LONG INTERSPERSED REPEAT; METABOLISM; PHOSPHORYLATION; RNA INTERFERENCE;

DNA VIRUSES;

CARRIER PROTEINS; CELL LINE; CELL PROLIFERATION; CYTOPLASMIC GRANULES; EIF-2 KINASE; EUKARYOTIC INITIATION FACTOR-4G; HEK293 CELLS; HELA CELLS; HUMANS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MONOMERIC GTP-BINDING PROTEINS; PHOSPHORYLATION; POLY(A)-BINDING PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84938783916     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005367     Document Type: Article

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