Traumatic Brain Injury Increases Cortical Glutamate Network Activity by Compromising GABAergic Control

Cerebral Cortex

Volumn 25, Issue 8, 2015, Pages 2306-2320

  Cantu, David ^a   Walker, Kendall ^a   Andresen, Lauren ^a,b   Taylor Weiner, Amaro ^a,c   Hampton, David ^a   Tesco, Giuseppina ^a   Dulla, Chris G ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS UNIVERSITY   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

cortical hyperexcitability; epilepsy; glutamate signaling; network reorganization; traumatic brain injury

Indexed keywords

3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 4 AMINOBUTYRIC ACID A RECEPTOR; GLUTAMIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; EXCITATORY AMINO ACID TRANSPORTER 1; EXCITATORY AMINO ACID TRANSPORTER 2; PARVALBUMIN; SLC1A2 PROTEIN, MOUSE; SLC1A3 PROTEIN, MOUSE; SOMATOSTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSENSOR; BRAIN SLICE; CONTROLLED STUDY; CORTICAL HYPEREXCITABILITY; DRUG RESISTANT EPILEPSY; EPILEPSY; EVOKED RESPONSE; EXCITATORY POSTSYNAPTIC POTENTIAL; FLUORESCENCE RESONANCE ENERGY TRANSFER; GABAERGIC SYSTEM; MALE; MOUSE; NERVE CELL EXCITABILITY; NONHUMAN; PATCH CLAMP TECHNIQUE; PRIORITY JOURNAL; RISK FACTOR; TRAUMATIC BRAIN INJURY; ANIMAL; ASTROCYTE; BRAIN CORTEX; BRAIN INJURY; C57BL MOUSE; DISEASE MODEL; INHIBITORY POSTSYNAPTIC POTENTIAL; METABOLISM; NERVE TRACT; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TISSUE CULTURE TECHNIQUE;

ANIMALS; ASTROCYTES; BRAIN INJURIES; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; EPILEPSY; EXCITATORY AMINO ACID TRANSPORTER 1; EXCITATORY AMINO ACID TRANSPORTER 2; EXCITATORY POSTSYNAPTIC POTENTIALS; GABAERGIC NEURONS; GLUTAMIC ACID; INHIBITORY POSTSYNAPTIC POTENTIALS; MALE; MICE, INBRED C57BL; NEURAL PATHWAYS; PARVALBUMINS; SOMATOSTATIN; TISSUE CULTURE TECHNIQUES;

EID: 84938631844     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhu041     Document Type: Article

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