Acute exposure to ZnO nanoparticles induces autophagic immune cell death

Nanotoxicology

Volumn 9, Issue 6, 2015, Pages 737-748

  Johnson, Brandon M ^a   Fraietta, Joseph A ^b   Gracias, Donald T ^c,e   Hope, Jennifer L ^c   Stairiker, Christopher J ^c   Patel, Prachi R ^b   Mueller, Yvonne M ^c,d   McHugh, Michael D ^a,f   Jablonowski, Lauren J ^a   Wheatley, Margaret A ^a   Katsikis, Peter D ^c,d  

^a DREXEL UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^f Yale University   (United States)

Author keywords

Autophagy; nanoparticles; ROS; toxicity; ZnO

Indexed keywords

CALCIUM CHLORIDE; GLUTATHIONE DISULFIDE; INTERLEUKIN 1BETA CONVERTING ENZYME; LIGHT CHAIN 3A; PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ZINC ION; ZINC OXIDE NANOPARTICLE; NANOPARTICLE; ZINC OXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; B LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DEATH; CELL SURVIVAL; CELL VACUOLE; CONTROLLED STUDY; CYTOTOXICITY; DENDRITIC CELL; DISSOLUTION; DNA DEGRADATION; DNA FRAGMENTATION; FEMALE; HUMAN; HUMAN CELL; HYDROLYSIS; IMMUNOCOMPETENT CELL; IMMUNOTOXICITY; IN VITRO STUDY; JURKAT CELL LINE; LYMPHOCYTE SUBPOPULATION; MACROPHAGE; MONOCYTE; MOUSE; NATURAL KILLER CELL; NECROPTOSIS; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SOLUBILITY; SPLEEN CELL; STEADY STATE; T CELL CULTURE; UPREGULATION; ZETA POTENTIAL; ANIMAL; C57BL MOUSE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; FLOW CYTOMETRY; IMMUNOLOGY; METABOLISM; PARTICLE SIZE; PATHOLOGY; SPLEEN; SURFACE PROPERTY; T LYMPHOCYTE;

MUS;

ANIMALS; AUTOPHAGY; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLOW CYTOMETRY; HUMANS; JURKAT CELLS; MICE, INBRED C57BL; NANOPARTICLES; PARTICLE SIZE; REACTIVE OXYGEN SPECIES; SPLEEN; SURFACE PROPERTIES; T-LYMPHOCYTES; ZINC OXIDE;

EID: 84938384258     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2014.974709     Document Type: Article

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