Inhibition of autophagy by 3-methyladenine protects 1321N1 astrocytoma cells against pyocyanin- and 1-hydroxyphenazine-induced toxicity

Archives of Toxicology

Volumn 86, Issue 2, 2012, Pages 275-284

  McFarland, Amelia J ^a,b   Anoopkumar Dukie, Shailendra ^a,b   Perkins, Anthony V ^a,b   Davey, Andrew K ^a,b   Grant, Gary D ^a,b  

^a GRIFFITH UNIVERSITY   (Australia)

^b GRIFFITH UNIVERSITY   (Australia)

Author keywords

1 hydroxyphenazine; 3 methyladenine; Acidic vesicular organelle (AVO); Astrocytes; Pyocyanin

Indexed keywords

1 HYDROXYPHENAZINE; 3 METHYLADENINE; PHENAZINE DERIVATIVE; PYOCYANINE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ASTROCYTOMA CELL; AUTOPHAGY; CELL PROLIFERATION; CELL PROTECTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; NEUROPROTECTION; NEUROTOXICITY; OXIDATIVE STRESS; PRIORITY JOURNAL; SENESCENCE; SYNAPSE VESICLE; TOXICITY TESTING;

ADENINE; ANTIOXIDANTS; APOPTOSIS; ASTROCYTES; ASTROCYTOMA; AUTOPHAGY; CELL AGING; CELL LINE, TUMOR; CELLS, CULTURED; DRUG INTERACTIONS; HUMANS; OXIDATIVE STRESS; PHENAZINES; PYOCYANINE; REACTIVE OXYGEN SPECIES;

MAMMALIA; PSEUDOMONAS AERUGINOSA;

EID: 84856949527     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0755-5     Document Type: Article

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