Increased level of exogenous zinc induces cytotoxicity and up-regulates the expression of the ZnT-1 zinc transporter gene in pancreatic cancer cells

Journal of Nutritional Biochemistry

Volumn 22, Issue 1, 2011, Pages 79-88

  Jayaraman, Arathi K ^a   Jayaraman, Sundararajan ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

Cytotoxicity; Islets; Mitochondria; Pancreatic carcinoma; Zinc transporters

Indexed keywords

ANTIOXIDANT; CASPASE; GLUTATHIONE; PROTEIN ZNT 1; SUPEROXIDE; THIOL DERIVATIVE; UNCLASSIFIED DRUG; ZINC; ZINC TRANSPORTER;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; INSULINOMA; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; NONHUMAN; PANCREAS ADENOCARCINOMA; PROTEIN EXPRESSION; RAT; UBIQUITINATION; UPREGULATION;

ANIMALS; ANTIOXIDANTS; CASPASES; CATION TRANSPORT PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; DRUG DESIGN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYDROGEN-ION CONCENTRATION; INSULIN-SECRETING CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; OSMOLAR CONCENTRATION; PANCREATIC NEOPLASMS; RATS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SULFHYDRYL COMPOUNDS; UBIQUITINATION; ZINC;

RATTUS;

EID: 78649912171     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2009.12.001     Document Type: Article

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