Toxic effect of different ZnO particles on mouse alveolar macrophages

Journal of Hazardous Materials

Volumn 219-220, Issue , 2012, Pages 148-155

  Zhang, Jinyang ^a,d   Song, Wenhua ^a,b   Guo, Jing ^b   Zhang, Jinhua ^b   Sun, Zengtian ^b   Ding, Feng ^c   Gao, Minling ^b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b TIANJIN POLYTECHNIC UNIVERSITY   (China)

^c NANKAI UNIVERSITY   (China)

^d NEIJIANG NORMAL UNIVERSITY   (China)

Author keywords

Antioxidation; Cell apoptosis; Mouse alveolar macrophages; Synthesis; Toxic effect; ZnO nanoparticles

Indexed keywords

ALVEOLAR MACROPHAGES; ANTI-OXIDATION; CELL APOPTOSIS; TOXIC EFFECT; ZNO NANOPARTICLES;

CELL DEATH; CELL MEMBRANES; DISSOLUTION; INDUSTRIAL POISONS; IONS; MACROPHAGES; MAMMALS; NANOPARTICLES; SYNTHESIS (CHEMICAL); TOXICITY; ZINC;

ZINC OXIDE;

METALLOTHIONEIN; NANOPARTICLE; ZINC OXIDE;

APOPTOSIS; CELL ORGANELLE; CONCENTRATION (COMPOSITION); MEMBRANE; MITOCHONDRION; OXIDE; PARTICULATE MATTER; RODENT; TOXIC SUBSTANCE; TOXICITY;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; IC 50; LUNG ALVEOLUS MACROPHAGE; MOUSE; NONHUMAN; PROTEIN SYNTHESIS; TOXICITY TESTING;

ANIMALS; APOPTOSIS; CALCIUM; CELL LINE; INHIBITORY CONCENTRATION 50; L-LACTATE DEHYDROGENASE; MACROPHAGES, ALVEOLAR; MEMBRANE POTENTIALS; MICE; REACTIVE OXYGEN SPECIES; ZINC OXIDE;

EID: 84860738210     PISSN: 03043894     EISSN: 18733336     Source Type: Journal    
DOI: 10.1016/j.jhazmat.2012.03.069     Document Type: Article

References (35)

1. Jeng H.A., Swanson J. Toxicity of metal oxide nanoparticles in mammalian cells. J. Environ. Sci. Health Part A: Toxic/Hazard. Subst. Environ. Eng. 2006, 41:2699-2711.
2. Lai J.C.K., Lai M.B., Jandhyam S., Dukhande V.V., Bhushan A., Daniels C.K., Leung S.W. Exposure to titanium dioxide and other metallic oxide nanoparticles induces cytotoxicity on human neural cells and fibroblasts. Int. J. Nanomed. 2008, 3:533-545.
3. Horie M., Nishio K., Fujita K., Endoh S., Miyauchi A., Saito Y., Iwahashi H., Yamamoto K., Murayama H., Nakano H., Nanashima N., Niki E., Yoshida Y. Protein adsorption of ultrafine metal oxide and its influence on cytotoxicity toward cultured cells. Chem. Res. Toxicol. 2009, 22:543-553.
4. Brunner T.J., Wick P., Manser P., Spohn P., Grass P.N., Limbach L., Bruinink A., Stark W.J. In vitro cytotoxicity of oxide nanoparticles: comparison to asbestos, silica, and the effect of particle solubility. Environ. Sci. Technol. 2006, 40:4374-4381.
5. Karlsson H.L., Cronholm P., Gustafsson J., Möller L. Copper oxide nanoparticles are highly toxic: a comparison between metal oxide nanoparticles and carbon nanotubes. Chem. Res. Toxicol. 2008, 21:1726-1732.
6. Xia T., Kovochich M., Liong M., Ma dler L., Gilbert B., Shi H., Yeh J.I., Zink J.I., Nel A.E. Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. ACS Nano 2008, 2:2121-2134.
7. Lin W., Xu Y., Huang C.C., Ma Y., Shannon K.B., Chen D.R., Huang Y.W. Toxicity of nano- and micro-sized ZnO particles in human lung epithelial cells. J. Nanopart. Res. 2009, 11:25-39.
8. Kim Y.H., Fazlollahi F., Kennedy I.M., Yacobi N.R., Hamm-Alvarez S.F., Borok Z., Kim K.J., Crandall E.D. Alveolar epithelial cell injury due to zinc oxide nanoparticle exposure. Am. J. Respir. Crit. Care Med. 2010, 182:1398-1409.
9. Song W., Zhang J., Guo J., Zhang J., Ding F., Li L., Sun Z. Role of the dissolved zinc ion and reactive oxygen species in cytotoxicity of ZnO nanoparticles. Toxicol. Lett. 2010, 199:389-397.
10. Baird S.K., Kurz T., Brunk U.T. Metallothionein protects against oxidative stress-induced lysosomal destabilization. Biochem. J. 2006, 394:275-283.
11. Morio L.A., Hooper K.A., Brittingham J., Li T.H., Gordon R.E., Turpin B.J., Laskin D.L. Tissue injury following inhalation of fine particulate matter and hydrogen peroxide is associated with altered production of inflammatory mediators and antioxidants by alveolar macrophages. Toxicol. Appl. Pharm. 2001, 177:188-199.
12. Beyerle A., Holger S., Kissel T., Stoeger T. Screening strategy to avoid toxicological hazards of inhaled nanoparticles for drug delivery: the use of α-quartz and nano zinc oxide particles as benchmark. J. Phys.: Conf. Ser. 2009, 151:012034.
13. Wan C.P., Myung E., Lau B.H. An automated micro-fluorometric assay for monitoring oxidative burst activity of phagocytes. J. Immunol. Methods 1993, 159:131-138.
14. Limbach L.K., Li Y., Grass R.N., Brunner T.J., Hintermann M.A., Muller M., Gunther D., Stark W.J. Oxide nanoparticle uptake in human lung fibroblasts: effects of particle size, agglomeration, and diffusion at low concentrations. Environ. Sci. Technol. 2005, 39:9370-9376.
15. Yang H., Liu C., Yang D., Zhang H., Xi Z. Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition. J. Appl. Toxicol. 2009, 29:69-78.
16. Huang C.C., Aronstam R.S., Chen D.R., Huang Y.W. Oxidative stress, calcium homeostasis, and altered gene expression in human lung epithelial cells exposed to ZnO nanoparticles. Toxicol. In Vitro 2010, 24:45-55.
17. Foley S., Crowley C., Smaihi M., Bonfils C., Erlanger F.B., Seta P., Larroque C. Cellular localization of a water-soluble fullerene derivatives. Biochem. Biophys. Res. Commun. 2002, 294:116-119.
18. Li N., Sioutas C., Cho A., Schmitz D., Misra C., Sempf J., Wang M., Oberley T., Froines J., Nel A. Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Environ. Health Perspect. 2003, 111:455-460.
19. Savic R., Luo L., Eisenberg A., Maysinger D. Micellar nanocontainers distribute to defined cytoplasmic organelles. Science 2003, 300:615-618.
20. Wiseman D.A., Wells S.M., Hubbard M., Welker J.E., Black S.M. Alterations in zinc homeostasis underlie endothelial cell death induced by oxidative stress from acute exposure to hydrogen peroxide. Am. J. Physiol. Lung Cell. Mol. Physiol. 2007, 292:L165-L177.
21. Marin P., Israel M., Glowinske J., Premont J. Routes of zinc entry in mouse cortical neurons: role in zinc-induced neurotoxicity. Eur. J. Neurosci. 2000, 12:8-18.
22. Daniels W.M.U., Hendricks J., Salie R., van Rensburg S.J. Amechanism for zinc toxicity in neuroblastoma cells. Metab. Brain Dis. 2004, 19:79-88.
23. Berardis B.D., Civitelli G., Condello M., Lista P., Pozzi R., Arancia G., Meschini S. Exposure to ZnO nanoparticles induces oxidative stress and cytotoxicity in human colon carcinoma cells. Toxicol. Appl. Pharmacol. 2010, 246:116-127.
24. Nair S., Sasidharan A., Divya Rani V.V., Menon D., Nair S., Manzoor K., Raina S. Role of size scale of ZnO nanoparticles and microparticles on toxicity toward bacteria and osteoblast cancer cells. J. Mater Sci.: Mater Med. 2009, 20:S235-S241.
25. 2 nanoparticles toward human lung epithelial cells. Sci. Total Environ. 2011, 409:1219-1228.
26. Sharma R., Sharma M., Datta P.K., Savin V.J. Induction of metallothionein-I protects glomeruli from superoxide-mediated increase in albumin permeability. Exp. Biol. Med. 2002, 227:26-31.
27. Li X., Chen H., Epstein P.N. Metallothionein protects islets from hypoxia and extends islet graft survival by scavenging most kinds of reactive oxygen species. J. Biol. Chem. 2004, 279:765-771.
28. Alscher D.M., Braun N., Biegger D., Stuelten C., Gawronski K., Mürdter T.E., Kuhlmann U., Fritz P. Induction of metallothionein in proximal tubular cells by zinc and its potential as an endogenous antioxidant. Kidney Blood Press. Res. 2005, 28:127-133.
29. Suntres Z.E., Lui E.M.K. Antioxidant effect of zinc and zinc-metallothionein in the acute cytotoxicity of hydrogen peroxide in Ehrlich ascites tumour cells. Chem. Biol. Interact. 2006, 162:11-23.
30. Davis S.R., Cousins R.J. Metallothionein expression in animals: a physiological perspective on function. J. Nutr. 2000, 130:1085-1088.
31. Davis S.R., Samuelson D.A., Cousins R.J. Metallothionein expression protects against carbon tetrachloride-induced hepatotoxicity, but overexpression and dietary zinc supplementation provide no further protection in metallothionein transgenic and knockout mice. J. Nutr. 2001, 131:215-222.
32. Medici V., Santon A., Sturniolo G.C., D'Incà R., Giannetto S., Albergoni V., Irato P. Metallothionein and antioxidant enzymes in Long-Evans cinnamon rats treated with zinc. Arch. Toxicol. 2002, 76:509-516.
33. Markant A., Pallaup I. Metallothionein and zinc as potential antioxidants in radical-induced lipid peroxidation in cultured hepatocytes. J. Trace Elem. Med. Biol. 1996, 10:88-95.
34. Formigari A., Irato P., Santon A. Zinc, antioxidant systems and metallothionein in metal mediated-apoptosis: biochemical and cytochemical aspects. Comp. Biochem. Physiol.: Part C 2007, 146:443-459.
35. Andrews G.K. Regulation of metallothionein gene expression by oxidative stress and metal ions. Biochem. Pharmacol. 2000, 59:95-104.