MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex

Nature Communications

Volumn 6, Issue , 2015, Pages

  Lee, Kyung Yong ^a   Im, Jun Sub ^a   Shibata, Etsuko ^a   Park, Jonghoon ^a   Handa, Naofumi ^b   Kowalczykowski, Stephen C ^b   Dutta, Anindya ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CISPLATIN; DOUBLE STRANDED DNA; ENDONUCLEASE; ENDONUCLEASE I SCEI; MINICHROMOSOME MAINTENANCE PROTEIN 8; MINICHROMOSOME MAINTENANCE PROTEIN 9; MRE11 PROTEIN; NIBRIN; RAD50 PROTEIN; SINGLE STRANDED DNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ABC TRANSPORTER; CARRIER PROTEIN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; DNA LIGASE; MCM8 PROTEIN, HUMAN; MCM8 PROTEIN, MOUSE; MCM8 PROTEIN, XENOPUS; MCM9 PROTEIN, HUMAN; MCM9 PROTEIN, MOUSE; MCM9 PROTEIN, XENOPUS; MINICHROMOSOME MAINTENANCE PROTEIN; MRE11 PROTEIN, XENOPUS; MRE11A PROTEIN, HUMAN; MRE11A PROTEIN, MOUSE; NBN PROTEIN, HUMAN; NBS1 PROTEIN, XENOPUS; NIJMEGEN BREAKAGE SYNDROME 1 PROTEIN, MOUSE; NUCLEAR PROTEIN; RAD50 PROTEIN, HUMAN; RAD50 PROTEIN, MOUSE; RAD50 PROTEIN, XENOPUS; TUMOR SUPPRESSOR PROTEIN; XENOPUS PROTEIN;

CANCER; GENE EXPRESSION; GENETIC ANALYSIS; MUTATION; PROTEIN;

ANIMAL CELL; ARTICLE; CANCER CELL LINE; CELL COUNT; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; DRUG SENSITIVITY; EMBRYO; ENZYME ACTIVITY; ENZYME REPRESSION; FEMALE; GENE DELETION; GENE INACTIVATION; GENE SILENCING; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; POINT MUTATION; PREMATURE OVARIAN FAILURE; PROSTATE CANCER CELL LINE; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RECOMBINATION REPAIR; SINGLE NUCLEOTIDE POLYMORPHISM; SQUAMOUS CELL LUNG CARCINOMA; TRANSIENT TRANSFECTION; U2OS CELL LINE; ANIMAL; CHROMATIN IMMUNOPRECIPITATION; DNA REPAIR; DOUBLE STRANDED DNA BREAK; HEK293 CELL LINE; HELA CELL LINE; METABOLISM; XENOPUS;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CHROMATIN IMMUNOPRECIPITATION; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA REPAIR; DNA REPAIR ENZYMES; DNA, SINGLE-STRANDED; DNA-BINDING PROTEINS; HEK293 CELLS; HELA CELLS; HUMANS; MICE; MINICHROMOSOME MAINTENANCE PROTEINS; NUCLEAR PROTEINS; RECOMBINATIONAL DNA REPAIR; TUMOR SUPPRESSOR PROTEINS; XENOPUS; XENOPUS PROTEINS;

EID: 84938089266     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8744     Document Type: Article

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