-
1
-
-
0345099477
-
A prospective, clinical and radiological study of early psoriatic arthritis: An early synovitis clinic experience
-
COI: 1:STN:280:DC%2BD3srntFyhtw%3D%3D
-
Kane D et al. A prospective, clinical and radiological study of early psoriatic arthritis: an early synovitis clinic experience. Rheumatology (Oxford). 2003;42(12):1460–8.
-
(2003)
Rheumatology (Oxford)
, vol.42
, Issue.12
, pp. 1460-1468
-
-
Kane, D.1
-
2
-
-
33751181855
-
Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis
-
PID: 17021763
-
Sommer DM et al. Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis. Arch Dermatol Res. 2006;298(7):321–8.
-
(2006)
Arch Dermatol Res
, vol.298
, Issue.7
, pp. 321-328
-
-
Sommer, D.M.1
-
3
-
-
84899758219
-
Depression and anxiety in psoriatic disease: Prevalence and associated factors
-
PID: 24692521
-
McDonough E et al. Depression and anxiety in psoriatic disease: prevalence and associated factors. J Rheumatol. 2014;41(5):887–96.
-
(2014)
J Rheumatol
, vol.41
, Issue.5
, pp. 887-896
-
-
McDonough, E.1
-
4
-
-
0027215897
-
CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene
-
COI: 1:CAS:528:DyaK3sXmtFylu7c%3D, PID: 8390535
-
Rouvier E et al. CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. J Immunol. 1993;150(12):5445–56.
-
(1993)
J Immunol
, vol.150
, Issue.12
, pp. 5445-5456
-
-
Rouvier, E.1
-
5
-
-
0029555301
-
Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor
-
COI: 1:CAS:528:DyaK28XhtF2gsw%3D%3D, PID: 8777726
-
Yao Z et al. Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity. 1995;3(6):811–21.
-
(1995)
Immunity
, vol.3
, Issue.6
, pp. 811-821
-
-
Yao, Z.1
-
6
-
-
0031282513
-
Molecular characterization of the human interleukin (IL)-17 receptor
-
COI: 1:CAS:528:DyaK2sXnslCjs7s%3D, PID: 9367539
-
Yao Z et al. Molecular characterization of the human interleukin (IL)-17 receptor. Cytokine. 1997;9(11):794–800.
-
(1997)
Cytokine
, vol.9
, Issue.11
, pp. 794-800
-
-
Yao, Z.1
-
7
-
-
84906535154
-
The IL-23-IL-17 immune axis: From mechanisms to therapeutic testing
-
COI: 1:CAS:528:DC%2BC2cXhsVSit7%2FL, PID: 25145755
-
Gaffen Jr SL, Garg AV, Cua DJ. The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing. Nat Rev Immunol. 2014;14(9):585–600.
-
(2014)
Nat Rev Immunol
, vol.14
, Issue.9
, pp. 585-600
-
-
Gaffen, S.L.1
Garg, A.V.2
Cua, D.J.3
-
8
-
-
0031802932
-
Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines
-
COI: 1:CAS:528:DyaK1cXktVynsbs%3D, PID: 9647250
-
Chabaud M et al. Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines. J Immunol. 1998;161(1):409–14.
-
(1998)
J Immunol
, vol.161
, Issue.1
, pp. 409-414
-
-
Chabaud, M.1
-
9
-
-
79953178961
-
Structure and function of interleukin-17 family cytokines
-
PID: 21337007
-
Zhang X et al. Structure and function of interleukin-17 family cytokines. Protein Cell. 2011;2(1):26–40.
-
(2011)
Protein Cell
, vol.2
, Issue.1
, pp. 26-40
-
-
Zhang, X.1
-
10
-
-
17944368518
-
IL-17s adopt a cystine knot fold: Structure and activity of a novel cytokine, IL-17F, and implications for receptor binding
-
COI: 1:CAS:528:DC%2BD38XjtVSrug%3D%3D, PID: 11574464
-
Hymowitz SG et al. IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding. EMBO J. 2001;20(19):5332–41.
-
(2001)
EMBO J
, vol.20
, Issue.19
, pp. 5332-5341
-
-
Hymowitz, S.G.1
-
11
-
-
82255175264
-
Cytokines: Il-17C joins the family firm
-
COI: 1:CAS:528:DC%2BC3MXhsVyktbzI, PID: 22094986
-
Bordon Y. Cytokines: IL-17C joins the family firm. Nat Rev Immunol. 2011;11(12):805.
-
(2011)
Nat Rev Immunol
, vol.11
, Issue.12
, pp. 805
-
-
Bordon, Y.1
-
12
-
-
84918821445
-
Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma
-
PID: 24949298
-
Farahani R et al. Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma. Adv Biomed Res. 2014;3:127.
-
(2014)
Adv Biomed Res
, vol.3
, pp. 127
-
-
Farahani, R.1
-
13
-
-
84868680647
-
New insight into the functions of the interleukin-17 receptor adaptor protein Act1 in psoriatic arthritis
-
COI: 1:CAS:528:DC%2BC38XhvVKjt73L, PID: 23116200
-
Doyle MS et al. New insight into the functions of the interleukin-17 receptor adaptor protein Act1 in psoriatic arthritis. Arthritis Res Ther. 2012;14(5):226.
-
(2012)
Arthritis Res Ther
, vol.14
, Issue.5
, pp. 226
-
-
Doyle, M.S.1
-
14
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
COI: 1:CAS:528:DC%2BD2MXhtFamsb7J, PID: 16200070
-
Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol. 2005;6(11):1123–32.
-
(2005)
Nat Immunol
, vol.6
, Issue.11
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
-
15
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
COI: 1:CAS:528:DC%2BD2MXot12mtA%3D%3D, PID: 15657292
-
Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med. 2005;201(2):233–40.
-
(2005)
J Exp Med
, vol.201
, Issue.2
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
-
16
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
COI: 1:CAS:528:DC%2BD28XksVGns7g%3D, PID: 16648838
-
Bettelli E et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. 2006;441(7090):235–8.
-
(2006)
Nature
, vol.441
, Issue.7090
, pp. 235-238
-
-
Bettelli, E.1
-
17
-
-
60749107176
-
The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo
-
COI: 1:CAS:528:DC%2BD1MXht1ehtLw%3D, PID: 19182808
-
McGeachy MJ et al. The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo. Nat Immunol. 2009;10(3):314–24.
-
(2009)
Nat Immunol
, vol.10
, Issue.3
, pp. 314-324
-
-
McGeachy, M.J.1
-
18
-
-
84866532132
-
-
Lee Y et al. Induction and molecular signature of pathogenic TH17 cells. Nat Immunol. 2012;13(10):991–9. This study compares the induction and gene expression profile of pathogenic and non pathogenic Th17 cells
-
Lee Y et al. Induction and molecular signature of pathogenic TH17 cells. Nat Immunol. 2012;13(10):991–9. This study compares the induction and gene expression profile of pathogenic and non pathogenic Th17 cells.
-
-
-
-
19
-
-
36248965294
-
TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology
-
COI: 1:CAS:528:DC%2BD2sXhtlajtr7K, PID: 17994024
-
McGeachy MJ et al. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology. Nat Immunol. 2007;8(12):1390–7.
-
(2007)
Nat Immunol
, vol.8
, Issue.12
, pp. 1390-1397
-
-
McGeachy, M.J.1
-
20
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
COI: 1:CAS:528:DC%2BD28XhtVCnsrrE, PID: 16990136
-
Ivanov II et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell. 2006;126(6):1121–33.
-
(2006)
Cell
, vol.126
, Issue.6
, pp. 1121-1133
-
-
Ivanov, I.I.1
-
21
-
-
34548128307
-
The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4
-
PID: 17676043
-
Brüstle A et al. The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat Immunol. 2007;8(9):958–66.
-
(2007)
Nat Immunol
, vol.8
, Issue.9
, pp. 958-966
-
-
Brüstle, A.1
-
22
-
-
34247593586
-
STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
-
COI: 1:CAS:528:DC%2BD2sXjtlCitr4%3D, PID: 17277312
-
Yang XO et al. STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. J Biol Chem. 2007;282(13):9358–63.
-
(2007)
J Biol Chem
, vol.282
, Issue.13
, pp. 9358-9363
-
-
Yang, X.O.1
-
23
-
-
66949180111
-
IL-23 drives pathogenic IL-17-producing CD8+ T cells
-
COI: 1:CAS:528:DC%2BD1MXkslKis7o%3D, PID: 19380776
-
Ciric B et al. IL-23 drives pathogenic IL-17-producing CD8+ T cells. J Immunol. 2009;182(9):5296–305.
-
(2009)
J Immunol
, vol.182
, Issue.9
, pp. 5296-5305
-
-
Ciric, B.1
-
24
-
-
79951677394
-
Fate mapping of IL-17-producing T cells in inflammatory responses
-
COI: 1:CAS:528:DC%2BC3MXht12msL8%3D, PID: 21278737
-
Hirota K et al. Fate mapping of IL-17-producing T cells in inflammatory responses. Nat Immunol. 2011;12(3):255–63.
-
(2011)
Nat Immunol
, vol.12
, Issue.3
, pp. 255-263
-
-
Hirota, K.1
-
25
-
-
82855178902
-
IL-17/IFN-gamma double producing CD8+ T (Tc17/IFN-gamma) cells: A novel cytotoxic T-cell subset converted from Tc17 cells by IL-12
-
COI: 1:CAS:528:DC%2BC3MXhsFKgur7F, PID: 22039016
-
Tajima M et al. IL-17/IFN-gamma double producing CD8+ T (Tc17/IFN-gamma) cells: a novel cytotoxic T-cell subset converted from Tc17 cells by IL-12. Int Immunol. 2011;23(12):751–9.
-
(2011)
Int Immunol
, vol.23
, Issue.12
, pp. 751-759
-
-
Tajima, M.1
-
26
-
-
78650764391
-
Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production
-
PID: 20954258
-
van Hamburg JP et al. Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production. Arthritis Rheum. 2011;63(1):73–83.
-
(2011)
Arthritis Rheum
, vol.63
, Issue.1
, pp. 73-83
-
-
van Hamburg, J.P.1
-
27
-
-
33646049742
-
Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene
-
COI: 1:CAS:528:DC%2BD28Xkt1Ggsrs%3D, PID: 16642438
-
Nair RP et al. Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene. Am J Hum Genet. 2006;78(5):827–51.
-
(2006)
Am J Hum Genet
, vol.78
, Issue.5
, pp. 827-851
-
-
Nair, R.P.1
-
28
-
-
84954215407
-
-
Haroon M., et al. Certain class I HLA alleles and haplotypes implicated in susceptibility play a role in determining specific features of the psoriatic arthritis phenotype. Ann Rheum Dis. 2014. doi:. This GWAS study reports that specific HLA alleles are associated with specific forms of PsA
-
Haroon M., et al. Certain class I HLA alleles and haplotypes implicated in susceptibility play a role in determining specific features of the psoriatic arthritis phenotype. Ann Rheum Dis. 2014. doi:10.1136/annrheumdis-2014-205461. This GWAS study reports that specific HLA alleles are associated with specific forms of PsA.
-
-
-
-
29
-
-
84863838472
-
HLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype
-
COI: 1:CAS:528:DC%2BC38XmvVygtbk%3D, PID: 22006066
-
Winchester R et al. HLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype. Arthritis Rheum. 2012;64(4):1134–44.
-
(2012)
Arthritis Rheum
, vol.64
, Issue.4
, pp. 1134-1144
-
-
Winchester, R.1
-
30
-
-
84865338050
-
The link between HLA-B27 and SpA—new ideas on an old problem
-
McHugh K, Bowness P. The link between HLA-B27 and SpA—new ideas on an old problem. Rheumatology (Oxford). 2012;51(9):1529–39.
-
(2012)
Rheumatology (Oxford)
, vol.51
, Issue.9
, pp. 1529-1539
-
-
McHugh, K.1
Bowness, P.2
-
31
-
-
34547774225
-
Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis
-
COI: 1:CAS:528:DC%2BD2sXoslGhtrs%3D, PID: 17587057
-
Capon F et al. Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis. Hum Genet. 2007;122(2):201–6.
-
(2007)
Hum Genet
, vol.122
, Issue.2
, pp. 201-206
-
-
Capon, F.1
-
32
-
-
67349230808
-
The IL-23/Th17 axis in the immunopathogenesis of psoriasis
-
PID: 19322214
-
Di Cesare A, Di Meglio P, Nestle FO. The IL-23/Th17 axis in the immunopathogenesis of psoriasis. J Invest Dermatol. 2009;129(6):1339–50.
-
(2009)
J Invest Dermatol
, vol.129
, Issue.6
, pp. 1339-1350
-
-
Di Cesare, A.1
Di Meglio, P.2
Nestle, F.O.3
-
33
-
-
78049350350
-
Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis
-
PID: 20953186
-
Huffmeier U et al. Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis. Nat Genet. 2010;42(11):996–9.
-
(2010)
Nat Genet
, vol.42
, Issue.11
, pp. 996-999
-
-
Huffmeier, U.1
-
34
-
-
33751546237
-
IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis
-
COI: 1:CAS:528:DC%2BD28Xht12htLbL, PID: 17074928
-
Chan JR et al. IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J Exp Med. 2006;203(12):2577–87.
-
(2006)
J Exp Med
, vol.203
, Issue.12
, pp. 2577-2587
-
-
Chan, J.R.1
-
35
-
-
66949162673
-
Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis
-
PID: 19380832
-
van der Fits L et al. Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis. J Immunol. 2009;182(9):5836–45.
-
(2009)
J Immunol
, vol.182
, Issue.9
, pp. 5836-5845
-
-
van der Fits, L.1
-
36
-
-
0035877257
-
Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death
-
COI: 1:CAS:528:DC%2BD3MXksVOmsLw%3D, PID: 11390512
-
Wiekowski MT et al. Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death. J Immunol. 2001;166(12):7563–70.
-
(2001)
J Immunol
, vol.166
, Issue.12
, pp. 7563-7570
-
-
Wiekowski, M.T.1
-
37
-
-
84863697312
-
IL-23 induces spondyloarthropathy by acting on ROR-gammat + CD3 + CD4-CD8- entheseal resident T cells
-
COI: 1:CAS:528:DC%2BC38XpsVWjtLk%3D, PID: 22772566
-
Sherlock JP et al. IL-23 induces spondyloarthropathy by acting on ROR-gammat + CD3 + CD4-CD8- entheseal resident T cells. Nat Med. 2012;18(7):1069–76.
-
(2012)
Nat Med
, vol.18
, Issue.7
, pp. 1069-1076
-
-
Sherlock, J.P.1
-
38
-
-
0346962972
-
Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
-
COI: 1:CAS:528:DC%2BD3sXpvFakur4%3D, PID: 14662908
-
Murphy CA et al. Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J Exp Med. 2003;198(12):1951–7.
-
(2003)
J Exp Med
, vol.198
, Issue.12
, pp. 1951-1957
-
-
Murphy, C.A.1
-
39
-
-
0344585384
-
Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
-
COI: 1:CAS:528:DC%2BD3sXptFOktrg%3D, PID: 14634133
-
Nakae S et al. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol. 2003;171(11):6173–7.
-
(2003)
J Immunol
, vol.171
, Issue.11
, pp. 6173-6177
-
-
Nakae, S.1
-
40
-
-
84858664948
-
Beta-glucan triggers spondylarthritis and Crohn’s disease-like ileitis in SKG mice
-
COI: 1:CAS:528:DC%2BC38XptFCgurw%3D, PID: 22328069
-
Ruutu M et al. Beta-glucan triggers spondylarthritis and Crohn’s disease-like ileitis in SKG mice. Arthritis Rheum. 2012;64(7):2211–22.
-
(2012)
Arthritis Rheum
, vol.64
, Issue.7
, pp. 2211-2222
-
-
Ruutu, M.1
-
41
-
-
84903473100
-
Interleukin-23 mediates the intestinal response to microbial beta-1,3-glucan and the development of spondyloarthritis pathology in SKG mice
-
COI: 1:CAS:528:DC%2BC2cXhsVCiu7rN, PID: 24664521
-
Benham H et al. Interleukin-23 mediates the intestinal response to microbial beta-1,3-glucan and the development of spondyloarthritis pathology in SKG mice. Arthritis Rheumatol. 2014;66(7):1755–67.
-
(2014)
Arthritis Rheumatol
, vol.66
, Issue.7
, pp. 1755-1767
-
-
Benham, H.1
-
42
-
-
33847077596
-
Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis
-
PID: 17265484
-
Lories RJ et al. Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis. Arthritis Rheum. 2007;56(2):489–97.
-
(2007)
Arthritis Rheum
, vol.56
, Issue.2
, pp. 489-497
-
-
Lories, R.J.1
-
43
-
-
84891747499
-
Proof of concept: Enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells
-
PID: 23921997
-
Jacques P et al. Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells. Ann Rheum Dis. 2014;73(2):437–45.
-
(2014)
Ann Rheum Dis
, vol.73
, Issue.2
, pp. 437-445
-
-
Jacques, P.1
-
44
-
-
54249130813
-
Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways
-
COI: 1:CAS:528:DC%2BD1cXhsV2ksLfP, PID: 18684158
-
Nograles KE et al. Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways. Br J Dermatol. 2008;159(5):1092–102.
-
(2008)
Br J Dermatol
, vol.159
, Issue.5
, pp. 1092-1102
-
-
Nograles, K.E.1
-
45
-
-
33749318470
-
Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
-
COI: 1:CAS:528:DC%2BD28XhtVGls7fF, PID: 16982811
-
Liang SC et al. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med. 2006;203(10):2271–9.
-
(2006)
J Exp Med
, vol.203
, Issue.10
, pp. 2271-2279
-
-
Liang, S.C.1
-
46
-
-
83555174764
-
IL-17 receptor and its functional significance in psoriatic arthritis
-
COI: 1:CAS:528:DC%2BC3MXhsV2hsrnJ, PID: 21894442
-
Raychaudhuri SP, Raychaudhuri SK, Genovese MC. IL-17 receptor and its functional significance in psoriatic arthritis. Mol Cell Biochem. 2012;359(1-2):419–29.
-
(2012)
Mol Cell Biochem
, vol.359
, Issue.1-2
, pp. 419-429
-
-
Raychaudhuri, S.P.1
Raychaudhuri, S.K.2
Genovese, M.C.3
-
47
-
-
84880664114
-
Synovial fibroblasts directly induce Th17 pathogenicity via the cyclooxygenase/prostaglandin E2 pathway, independent of IL-23
-
COI: 1:CAS:528:DC%2BC3sXhtFCjsr%2FF, PID: 23817417
-
Paulissen SM et al. Synovial fibroblasts directly induce Th17 pathogenicity via the cyclooxygenase/prostaglandin E2 pathway, independent of IL-23. J Immunol. 2013;191(3):1364–72.
-
(2013)
J Immunol
, vol.191
, Issue.3
, pp. 1364-1372
-
-
Paulissen, S.M.1
-
48
-
-
70350510860
-
IL-17 induces osteoclastogenesis from human monocytes alone in the absence of osteoblasts, which is potently inhibited by anti-TNF-alpha antibody: A novel mechanism of osteoclastogenesis by IL-17
-
COI: 1:CAS:528:DC%2BD1MXhtlSqs7rN, PID: 19728295
-
Yago T et al. IL-17 induces osteoclastogenesis from human monocytes alone in the absence of osteoblasts, which is potently inhibited by anti-TNF-alpha antibody: a novel mechanism of osteoclastogenesis by IL-17. J Cell Biochem. 2009;108(4):947–55.
-
(2009)
J Cell Biochem
, vol.108
, Issue.4
, pp. 947-955
-
-
Yago, T.1
-
49
-
-
84859833805
-
Role of osteoclasts and interleukin-17 in the pathogenesis of rheumatoid arthritis: Crucial ‘human osteoclastology’
-
COI: 1:CAS:528:DC%2BC38XjvFKrs7c%3D, PID: 21960179
-
Kotake S et al. Role of osteoclasts and interleukin-17 in the pathogenesis of rheumatoid arthritis: crucial ‘human osteoclastology’. J Bone Miner Metab. 2012;30(2):125–35.
-
(2012)
J Bone Miner Metab
, vol.30
, Issue.2
, pp. 125-135
-
-
Kotake, S.1
-
50
-
-
78649666553
-
Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis
-
PID: 21124836
-
Res PC et al. Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis. PLoS One. 2010;5(11), e14108.
-
(2010)
PLoS One
, vol.5
, Issue.11
-
-
Res, P.C.1
-
51
-
-
69449095507
-
IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines
-
COI: 1:CAS:528:DC%2BD1MXps1elsrc%3D, PID: 19487306
-
Ortega C et al. IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines. J Leukoc Biol. 2009;86(2):435–43.
-
(2009)
J Leukoc Biol
, vol.86
, Issue.2
, pp. 435-443
-
-
Ortega, C.1
-
52
-
-
79959584686
-
Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis
-
COI: 1:CAS:528:DC%2BC3MXnvValtbY%3D, PID: 21606249
-
Lin AM et al. Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis. J Immunol. 2011;187(1):490–500.
-
(2011)
J Immunol
, vol.187
, Issue.1
, pp. 490-500
-
-
Lin, A.M.1
-
53
-
-
58149331211
-
Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells
-
COI: 1:CAS:528:DC%2BD1cXhsVymu7%2FK, PID: 18633443
-
Zaba LC et al. Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells. J Invest Dermatol. 2009;129(1):79–88.
-
(2009)
J Invest Dermatol
, vol.129
, Issue.1
, pp. 79-88
-
-
Zaba, L.C.1
-
54
-
-
71749085498
-
Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes
-
PID: 19895991
-
Zaba LC et al. Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes. J Allergy Clin Immunol. 2009;124(5):1022-10 e1–395.
-
(2009)
J Allergy Clin Immunol
, vol.124
, Issue.5
-
-
Zaba, L.C.1
-
55
-
-
84899717815
-
-
Menon B et al. Interleukin-17 + CD8+ T cells are enriched in the joints of patients with psoriatic arthritis and correlate with disease activity and joint damage progression. Arthritis Rheumatol. 2014;66(5):1272–81. The first study reporting the presence of Tc17 cells in the synovial fluid of patients with PsA but not RA
-
Menon B et al. Interleukin-17 + CD8+ T cells are enriched in the joints of patients with psoriatic arthritis and correlate with disease activity and joint damage progression. Arthritis Rheumatol. 2014;66(5):1272–81. The first study reporting the presence of Tc17 cells in the synovial fluid of patients with PsA but not RA.
-
-
-
-
56
-
-
77957689108
-
Role of Th17 cells in human autoimmune arthritis
-
COI: 1:CAS:528:DC%2BC3cXhsVSqtrrK, PID: 20583102
-
Leipe J et al. Role of Th17 cells in human autoimmune arthritis. Arthritis Rheum. 2010;62(10):2876–85.
-
(2010)
Arthritis Rheum
, vol.62
, Issue.10
, pp. 2876-2885
-
-
Leipe, J.1
-
57
-
-
84904545875
-
-
Langley RG et al. Secukinumab in plaque psoriasis—results of two phase 3 trials. N Engl J Med. 2014;371(4):326–38. This paper reports the results of the first phase III clinical trial of a monoclonal antibody blocking IL-17A in PsO
-
Langley RG et al. Secukinumab in plaque psoriasis—results of two phase 3 trials. N Engl J Med. 2014;371(4):326–38. This paper reports the results of the first phase III clinical trial of a monoclonal antibody blocking IL-17A in PsO.
-
-
-
-
58
-
-
84859073115
-
Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis
-
COI: 1:CAS:528:DC%2BC38XlsVClu7o%3D, PID: 22455413
-
Leonardi C et al. Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis. N Engl J Med. 2012;366(13):1190–9.
-
(2012)
N Engl J Med
, vol.366
, Issue.13
, pp. 1190-1199
-
-
Leonardi, C.1
-
59
-
-
84902209516
-
Brodalumab, an anti-IL17RA monoclonal antibody, in psoriatic arthritis
-
PID: 24918373
-
Mease PJ et al. Brodalumab, an anti-IL17RA monoclonal antibody, in psoriatic arthritis. N Engl J Med. 2014;370(24):2295–306.
-
(2014)
N Engl J Med
, vol.370
, Issue.24
, pp. 2295-2306
-
-
Mease, P.J.1
-
60
-
-
84891740105
-
Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: A 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial
-
COI: 1:CAS:528:DC%2BC2cXltFKhs70%3D, PID: 23361084
-
McInnes IB et al. Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial. Ann Rheum Dis. 2014;73(2):349–56.
-
(2014)
Ann Rheum Dis
, vol.73
, Issue.2
, pp. 349-356
-
-
McInnes, I.B.1
-
61
-
-
84898658026
-
Gene expression profiles normalized in psoriatic skin by treatment with brodalumab, a human anti-IL-17 receptor monoclonal antibody
-
COI: 1:CAS:528:DC%2BC2cXls1Gmt7s%3D, PID: 24646743
-
Russell CB et al. Gene expression profiles normalized in psoriatic skin by treatment with brodalumab, a human anti-IL-17 receptor monoclonal antibody. J Immunol. 2014;192(8):3828–36.
-
(2014)
J Immunol
, vol.192
, Issue.8
, pp. 3828-3836
-
-
Russell, C.B.1
-
62
-
-
0036733724
-
The T cell receptor repertoire in psoriatic synovitis is restricted and T lymphocytes expressing the same TCR are present in joint and skin lesions
-
COI: 1:CAS:528:DC%2BD38Xns1aksLk%3D, PID: 12233886
-
Borgato L et al. The T cell receptor repertoire in psoriatic synovitis is restricted and T lymphocytes expressing the same TCR are present in joint and skin lesions. J Rheumatol. 2002;29(9):1914–9.
-
(2002)
J Rheumatol
, vol.29
, Issue.9
, pp. 1914-1919
-
-
Borgato, L.1
-
63
-
-
0035865217
-
Psoriatic arthritis joint fluids are characterised by CD8 and CD4 T cell clonal expansions appear antigen driven
-
COI: 1:CAS:528:DC%2BD3MXht1Ghsbo%3D, PID: 11160357
-
Costello PJ, Winchester RJ, Curran SA, Peterson KS, Kane DJ, Bresnihan B, et al. Psoriatic arthritis joint fluids are characterised by CD8 and CD4 T cell clonal expansions appear antigen driven. J Immunol. 2001;166(4):2878–86.
-
(2001)
J Immunol
, vol.166
, Issue.4
, pp. 2878-2886
-
-
Costello, P.J.1
Winchester, R.J.2
Curran, S.A.3
Peterson, K.S.4
Kane, D.J.5
Bresnihan, B.6
-
64
-
-
84925831707
-
-
Belasco J et al. Comparative genomic profiling of synovium versus skin lesions in psoriatic arthritis. Arthritis Rheumatol. 2015;67(4):934–44. This study reports differences between gene expression profiles between the skin and synovial tissue of patients with PsO and PsA suggesting the presence of underlying differences in the pathogenesis of these diseases
-
Belasco J et al. Comparative genomic profiling of synovium versus skin lesions in psoriatic arthritis. Arthritis Rheumatol. 2015;67(4):934–44. This study reports differences between gene expression profiles between the skin and synovial tissue of patients with PsO and PsA suggesting the presence of underlying differences in the pathogenesis of these diseases.
-
-
-
-
65
-
-
77953648234
-
HIV-associated psoriasis: Pathogenesis, clinical features, and management
-
COI: 1:CAS:528:DC%2BC3cXpslKnt7w%3D, PID: 20610329
-
Morar N et al. HIV-associated psoriasis: pathogenesis, clinical features, and management. Lancet Infect Dis. 2010;10(7):470–8.
-
(2010)
Lancet Infect Dis
, vol.10
, Issue.7
, pp. 470-478
-
-
Morar, N.1
-
66
-
-
0031821047
-
Dermatological findings correlated with CD4 lymphocyte counts in a prospective 3 year study of 1161 patients with human immunodeficiency virus disease predominantly acquired through intravenous drug abuse
-
COI: 1:STN:280:DyaK1cvjs1KgtQ%3D%3D, PID: 9764146
-
Munoz-Perez MA et al. Dermatological findings correlated with CD4 lymphocyte counts in a prospective 3 year study of 1161 patients with human immunodeficiency virus disease predominantly acquired through intravenous drug abuse. Br J Dermatol. 1998;139(1):33–9.
-
(1998)
Br J Dermatol
, vol.139
, Issue.1
, pp. 33-39
-
-
Munoz-Perez, M.A.1
-
67
-
-
84873825806
-
IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis
-
COI: 1:CAS:528:DC%2BC3sXnsFGntQ%3D%3D, PID: 23221338
-
Huber M et al. IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis. J Clin Invest. 2013;123(1):247–60.
-
(2013)
J Clin Invest
, vol.123
, Issue.1
, pp. 247-260
-
-
Huber, M.1
-
68
-
-
84861801523
-
Rorgammat + innate lymphocytes and gammadelta T cells initiate psoriasiform plaque formation in mice
-
COI: 1:CAS:528:DC%2BC38XosFaqsrg%3D, PID: 22546855
-
Pantelyushin S et al. Rorgammat + innate lymphocytes and gammadelta T cells initiate psoriasiform plaque formation in mice. J Clin Invest. 2012;122(6):2252–6.
-
(2012)
J Clin Invest
, vol.122
, Issue.6
, pp. 2252-2256
-
-
Pantelyushin, S.1
-
69
-
-
84900868717
-
In vivo induction of cutaneous inflammation results in the accumulation of extracellular trap-forming neutrophils expressing RORgammat and IL-17
-
COI: 1:CAS:528:DC%2BC2cXltVyhuw%3D%3D, PID: 24317395
-
Keijsers RR et al. In vivo induction of cutaneous inflammation results in the accumulation of extracellular trap-forming neutrophils expressing RORgammat and IL-17. J Invest Dermatol. 2014;134(5):1276–84.
-
(2014)
J Invest Dermatol
, vol.134
, Issue.5
, pp. 1276-1284
-
-
Keijsers, R.R.1
-
70
-
-
84855291352
-
Interleukin-17-positive mast cells contribute to synovial inflammation in spondylarthritis
-
COI: 1:CAS:528:DC%2BC3MXhs12mtbvJ, PID: 21968742
-
Noordenbos T et al. Interleukin-17-positive mast cells contribute to synovial inflammation in spondylarthritis. Arthritis Rheum. 2012;64(1):99–109.
-
(2012)
Arthritis Rheum
, vol.64
, Issue.1
, pp. 99-109
-
-
Noordenbos, T.1
-
71
-
-
73349101421
-
Tc17 CD8 T cells: Functional plasticity and subset diversity
-
COI: 1:CAS:528:DC%2BD1MXhsVehsbrE, PID: 19917680
-
Yen HR et al. Tc17 CD8 T cells: functional plasticity and subset diversity. J Immunol. 2009;183(11):7161–8.
-
(2009)
J Immunol
, vol.183
, Issue.11
, pp. 7161-7168
-
-
Yen, H.R.1
-
72
-
-
77953238901
-
Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage
-
COI: 1:CAS:528:DC%2BC3cXnt1Kls70%3D, PID: 20471290
-
Mukasa R et al. Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage. Immunity. 2010;32(5):616–27.
-
(2010)
Immunity
, vol.32
, Issue.5
, pp. 616-627
-
-
Mukasa, R.1
-
73
-
-
84865796294
-
The development of IL-17/IFN-gamma-double producing CTLs from Tc17 cells is driven by epigenetic suppression of Socs3 gene promoter
-
COI: 1:CAS:528:DC%2BC38XpvVelsr0%3D, PID: 22674086
-
Satoh T et al. The development of IL-17/IFN-gamma-double producing CTLs from Tc17 cells is driven by epigenetic suppression of Socs3 gene promoter. Eur J Immunol. 2012;42(9):2329–42.
-
(2012)
Eur J Immunol
, vol.42
, Issue.9
, pp. 2329-2342
-
-
Satoh, T.1
-
74
-
-
82355169754
-
A critical role for regulatory T cells in driving cytokine profiles of Th17 cells and their modulation of glioma microenvironment
-
COI: 1:CAS:528:DC%2BC3MXhsFantrrE, PID: 21779877
-
Cantini G et al. A critical role for regulatory T cells in driving cytokine profiles of Th17 cells and their modulation of glioma microenvironment. Cancer Immunol Immunother. 2011;60(12):1739–50.
-
(2011)
Cancer Immunol Immunother
, vol.60
, Issue.12
, pp. 1739-1750
-
-
Cantini, G.1
-
75
-
-
84893850913
-
TNF-alpha blockade induces IL-10 expression in human CD4+ T cells
-
PID: 24492460
-
Evans HG et al. TNF-alpha blockade induces IL-10 expression in human CD4+ T cells. Nat Commun. 2014;5:3199.
-
(2014)
Nat Commun
, vol.5
, pp. 3199
-
-
Evans, H.G.1
-
76
-
-
79954620910
-
Th17 cells express interleukin-10 receptor and are controlled by Foxp3(−) and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner
-
COI: 1:CAS:528:DC%2BC3MXltVGmsb4%3D, PID: 21511184
-
Huber S et al. Th17 cells express interleukin-10 receptor and are controlled by Foxp3(−) and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner. Immunity. 2011;34(4):554–65.
-
(2011)
Immunity
, vol.34
, Issue.4
, pp. 554-565
-
-
Huber, S.1
-
77
-
-
43449111187
-
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
-
COI: 1:CAS:528:DC%2BD1cXlvFymt7o%3D, PID: 18486739
-
Leonardi CL et al. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1). Lancet. 2008;371(9625):1665–74.
-
(2008)
Lancet
, vol.371
, Issue.9625
, pp. 1665-1674
-
-
Leonardi, C.L.1
-
78
-
-
84883134297
-
Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial
-
COI: 1:CAS:528:DC%2BC3sXpsV2ksbw%3D, PID: 23769296
-
McInnes IB et al. Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial. Lancet. 2013;382(9894):780–9.
-
(2013)
Lancet
, vol.382
, Issue.9894
, pp. 780-789
-
-
McInnes, I.B.1
-
79
-
-
43449139402
-
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)
-
COI: 1:CAS:528:DC%2BD1cXlvFymt7s%3D, PID: 18486740
-
Papp KA et al. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2). Lancet. 2008;371(9625):1675–84.
-
(2008)
Lancet
, vol.371
, Issue.9625
, pp. 1675-1684
-
-
Papp, K.A.1
-
80
-
-
84899991797
-
Efficacy and safety of the anti-IL-12/23 p40 monoclonal antibody, ustekinumab, in patients with active psoriatic arthritis despite conventional non-biological and biological anti-tumour necrosis factor therapy: 6-month and 1-year results of the phase 3, multicentre, double-blind, placebo-controlled, randomised PSUMMIT 2 trial
-
COI: 1:CAS:528:DC%2BC2cXhtV2isLzF, PID: 24482301
-
Ritchlin C et al. Efficacy and safety of the anti-IL-12/23 p40 monoclonal antibody, ustekinumab, in patients with active psoriatic arthritis despite conventional non-biological and biological anti-tumour necrosis factor therapy: 6-month and 1-year results of the phase 3, multicentre, double-blind, placebo-controlled, randomised PSUMMIT 2 trial. Ann Rheum Dis. 2014;73(6):990–9.
-
(2014)
Ann Rheum Dis
, vol.73
, Issue.6
, pp. 990-999
-
-
Ritchlin, C.1
-
81
-
-
84859017988
-
Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis
-
COI: 1:CAS:528:DC%2BC38XlsVClu70%3D, PID: 22455412
-
Papp KA et al. Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis. N Engl J Med. 2012;366(13):1181–9.
-
(2012)
N Engl J Med
, vol.366
, Issue.13
, pp. 1181-1189
-
-
Papp, K.A.1
-
82
-
-
84938112060
-
-
McInnes IB, et al. Secukinumab, a human anti-interleukin-17A monoclonal antibody, improves active psoriatic arthritis: 24-week efficacy and safety data from a phase 3 randomized, multicenter, double-blind, placebo-controlled study using subcutaneous dosing. ACR 2014 Meeting Abstract, This abstract from the ACR 2014 meeting reports the results of the first phase III clinical trial of a monoclonal antibody blocking IL-17A in PsA. This abstract from the ACR 2014 meeting reports the results of the first phase III clinical trial of a monoclonal antibody blocking IL-17A in PsA
-
McInnes IB, et al. Secukinumab, a human anti-interleukin-17A monoclonal antibody, improves active psoriatic arthritis: 24-week efficacy and safety data from a phase 3 randomized, multicenter, double-blind, placebo-controlled study using subcutaneous dosing. ACR 2014 Meeting Abstract, http://acrabstracts.org/abstracts/secukinumab-a-human-anti-interleukin-17a-monoclonal-antibody-improves-active-psoriatic-arthritis-24-week-efficacy-and-safety-data-from-a-phase-3-randomized-multicenter-double-blind-placebo-contr/This abstract from the ACR 2014 meeting reports the results of the first phase III clinical trial of a monoclonal antibody blocking IL-17A in PsA. This abstract from the ACR 2014 meeting reports the results of the first phase III clinical trial of a monoclonal antibody blocking IL-17A in PsA.
-
-
-
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