Vitamin D3 enhances the tumouricidal effects of 5-Fluorouracil through multipathway mechanisms in azoxymethane rat model of colon cancer

Journal of Experimental and Clinical Cancer Research

Volumn 34, Issue 1, 2015, Pages

  Refaat, Bassem ^a   El Shemi, Adel Galal ^a,b   Kensara, Osama Adnan ^a   Mohamed, Amr Mohamed ^a,c   Idris, Shakir ^a   Ahmad, Jawwad ^a   Khojah, Athar ^a  

^a UMM AL QURA UNIVERSITY   (Saudi Arabia)

^b Assiut University Faculty of Medicine   (Egypt)

^c Assiut University   (Egypt)

Author keywords

Colon cancer; COX 2; HSP 90; iNOS; TGF ; Therapeutic efficacy; Vitamin D3; catenin

Indexed keywords

AZOXYMETHANE; BETA CATENIN; COLECALCIFEROL; CYCLOOXYGENASE 2; DICKKOPF 1 PROTEIN; FLUOROURACIL; HEAT SHOCK PROTEIN 90; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; COLON; COLON CANCER; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT MODEL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE HOMOGENATE; WISTAR RAT; ANALOGS AND DERIVATIVES; ANIMAL; COLONIC NEOPLASMS; DISEASE MODEL; DRUG SCREENING; HUMAN; METABOLISM; MOUSE;

ANIMALS; BETA CATENIN; CHOLECALCIFEROL; COLONIC NEOPLASMS; DISEASE MODELS, ANIMAL; FLUOROURACIL; HUMANS; MALE; MICE; RATS; RATS, WISTAR; TRANSFORMING GROWTH FACTOR BETA; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84937933536     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/s13046-015-0187-9     Document Type: Article

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