메뉴 건너뛰기




Volumn 73, Issue 21, 2013, Pages 6526-6537

Nitric oxide production upregulates Wnt/β-catenin signaling by inhibiting dickkopf-1

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; DICKKOPF 1 PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NITRIC OXIDE; WNT PROTEIN;

EID: 84887179035     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-1620     Document Type: Article
Times cited : (54)

References (50)
  • 2
    • 42549164807 scopus 로고    scopus 로고
    • Wnt signalling and its impact on development and cancer
    • Klaus A, Birchmeier W. Wnt signalling and its impact on development and cancer. Nat Rev Cancer 2008;8: 387-98.
    • (2008) Nat Rev Cancer , vol.8 , pp. 387-398
    • Klaus, A.1    Birchmeier, W.2
  • 5
    • 0031728358 scopus 로고    scopus 로고
    • P53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells
    • Ambs S, Merriam WG, Ogunfusika MO, Bennett WP, Ishibe N, Hussain SP, et al. p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells. Nat Med 1998;4: 1371-6.
    • (1998) Nat Med , vol.4 , pp. 1371-1376
    • Ambs, S.1    Merriam, W.G.2    Ogunfusika, M.O.3    Bennett, W.P.4    Ishibe, N.5    Hussain, S.P.6
  • 6
    • 0031984809 scopus 로고    scopus 로고
    • Frequent nitric oxide synthase-2 expression in human colon adenomas: Implication for tumor angiogenesis and colon cancer progression
    • Ambs S, Merriam WG, Bennett WP, Felley-Bosco E, Ogunfusika MO, Oser SM, et al. Frequent nitric oxide synthase-2 expression in human colon adenomas: implication for tumor angiogenesis and colon cancer progression. Cancer Res 1998;58: 334-41.
    • (1998) Cancer Res , vol.58 , pp. 334-341
    • Ambs, S.1    Merriam, W.G.2    Bennett, W.P.3    Felley-Bosco, E.4    Ogunfusika, M.O.5    Oser, S.M.6
  • 7
    • 79951866285 scopus 로고    scopus 로고
    • Candidate pathways linking inducible nitric oxide synthase to a basal-like transcription pattern and tumor progression in human breast cancer
    • Ambs S, Glynn SA. Candidate pathways linking inducible nitric oxide synthase to a basal-like transcription pattern and tumor progression in human breast cancer. Cell Cycle 2011;10: 619-24.
    • (2011) Cell Cycle , vol.10 , pp. 619-624
    • Ambs, S.1    Glynn, S.A.2
  • 8
    • 78049426509 scopus 로고    scopus 로고
    • Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients
    • Glynn SA, Boersma BJ, Dorsey TH, Yi M, Yfantis HG, Ridnour LA, et al. Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients. J Clin Invest 2010;120: 3843-54.
    • (2010) J Clin Invest , vol.120 , pp. 3843-3854
    • Glynn, S.A.1    Boersma, B.J.2    Dorsey, T.H.3    Yi, M.4    Yfantis, H.G.5    Ridnour, L.A.6
  • 10
    • 59049099999 scopus 로고    scopus 로고
    • Nitric oxide and TNF-alpha trigger colonic inflammation and carcinogenesis in Helicobacter hepaticus-infected, Rag2-deficient mice
    • Erdman SE, Rao VP, Poutahidis T, Rogers AB, Taylor CL, Jackson EA, et al. Nitric oxide and TNF-alpha trigger colonic inflammation and carcinogenesis in Helicobacter hepaticus-infected, Rag2-deficient mice. Proc Natl Acad Sci U S A 2009;106: 1027-32.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 1027-1032
    • Erdman, S.E.1    Rao, V.P.2    Poutahidis, T.3    Rogers, A.B.4    Taylor, C.L.5    Jackson, E.A.6
  • 12
    • 4344691283 scopus 로고    scopus 로고
    • Decreased Helicobacter pylori associated gastric carcinogenesis in mice lacking inducible nitric oxide synthase
    • Nam KT, Oh SY, Ahn B, Kim YB, Jang DD, Yang KH, et al. Decreased Helicobacter pylori associated gastric carcinogenesis in mice lacking inducible nitric oxide synthase. Gut 2004;53: 1250-5.
    • (2004) Gut , vol.53 , pp. 1250-1255
    • Nam, K.T.1    Oh, S.Y.2    Ahn, B.3    Kim, Y.B.4    Jang, D.D.5    Yang, K.H.6
  • 13
    • 0025015168 scopus 로고
    • A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
    • Moser AR, Pitot HC, Dove WF. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 1990; 247: 322-4.
    • (1990) Science , vol.247 , pp. 322-324
    • Moser, A.R.1    Pitot, H.C.2    Dove, W.F.3
  • 14
    • 0035577764 scopus 로고    scopus 로고
    • Suppression of intestinal polyposis in Apc(Min/+) mice by inhibiting nitric oxide production
    • Ahn B, Ohshima H. Suppression of intestinal polyposis in Apc(Min/+) mice by inhibiting nitric oxide production. Cancer Res 2001;61: 8357-60.
    • (2001) Cancer Res , vol.61 , pp. 8357-8360
    • Ahn, B.1    Ohshima, H.2
  • 15
    • 33746864818 scopus 로고    scopus 로고
    • Regulation of human nitric oxide synthase 2 expression by Wnt beta-catenin signaling
    • Du Q, Park KS, Guo Z, He P, Nagashima M, Shao L, et al. Regulation of human nitric oxide synthase 2 expression by Wnt beta-catenin signaling. Cancer Res 2006;66: 7024-31.
    • (2006) Cancer Res , vol.66 , pp. 7024-7031
    • Du, Q.1    Park, K.S.2    Guo, Z.3    He, P.4    Nagashima, M.5    Shao, L.6
  • 16
    • 65949106610 scopus 로고    scopus 로고
    • Wnt/betacatenin signaling regulates cytokine-induced human inducible nitric oxide synthase expression by inhibiting nuclear factor-kappaB activation in cancer cells
    • Du Q, Zhang X, Cardinal J, Cao Z, Guo Z, Shao L, et al. Wnt/betacatenin signaling regulates cytokine-induced human inducible nitric oxide synthase expression by inhibiting nuclear factor-kappaB activation in cancer cells. Cancer Res 2009;69: 3764-71.
    • (2009) Cancer Res , vol.69 , pp. 3764-3771
    • Du, Q.1    Zhang, X.2    Cardinal, J.3    Cao, Z.4    Guo, Z.5    Shao, L.6
  • 17
    • 84858706841 scopus 로고    scopus 로고
    • Cross-regulation between Wnt and NF-kappaB signaling pathways
    • Du Q, Geller DA. Cross-regulation between Wnt and NF-kappaB signaling pathways. For Immunopathol Dis Therap 2010;1: 155-81.
    • (2010) For Immunopathol Dis Therap , vol.1 , pp. 155-181
    • Du, Q.1    Geller, D.A.2
  • 19
    • 0142242181 scopus 로고    scopus 로고
    • Nitric oxide activates diverse signaling pathways to regulate gene expression
    • Hemish J, Nakaya N, Mittal V, Enikolopov G. Nitric oxide activates diverse signaling pathways to regulate gene expression. J Biol Chem 2003;278: 42321-9.
    • (2003) J Biol Chem , vol.278 , pp. 42321-42329
    • Hemish, J.1    Nakaya, N.2    Mittal, V.3    Enikolopov, G.4
  • 20
    • 0030584092 scopus 로고    scopus 로고
    • Nitric oxide regulates cell proliferation during Drosophila development
    • Kuzin B, Roberts I, Peunova N, Enikolopov G. Nitric oxide regulates cell proliferation during Drosophila development. Cell 1996;87: 639-49.
    • (1996) Cell , vol.87 , pp. 639-649
    • Kuzin, B.1    Roberts, I.2    Peunova, N.3    Enikolopov, G.4
  • 21
    • 0034485823 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival
    • Ekmekcioglu S, Ellerhorst J, Smid CM, Prieto VG, Munsell M, Buzaid AC, et al. Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival. Clin Cancer Res 2000;6: 4768-75.
    • (2000) Clin Cancer Res , vol.6 , pp. 4768-4775
    • Ekmekcioglu, S.1    Ellerhorst, J.2    Smid, C.M.3    Prieto, V.G.4    Munsell, M.5    Buzaid, A.C.6
  • 23
    • 79959969874 scopus 로고    scopus 로고
    • Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2
    • Eyler CE,WuQ, Yan K, MacSwords JM, Chandler-Militello D, Misuraca KL, et al. Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2. Cell 2011;146: 53-66.
    • (2011) Cell , vol.146 , pp. 53-66
    • Eyler, C.E.1    Wu, Q.2    Yan, K.3    MacSwords, J.M.4    Chandler-Militello, D.5    Misuraca, K.L.6
  • 24
  • 25
    • 33745559710 scopus 로고    scopus 로고
    • The role of nitric oxide in tumour progression
    • Fukumura D, Kashiwagi S, Jain RK. The role of nitric oxide in tumour progression. Nat Rev Cancer 2006;6: 521-34.
    • (2006) Nat Rev Cancer , vol.6 , pp. 521-534
    • Fukumura, D.1    Kashiwagi, S.2    Jain, R.K.3
  • 26
    • 33845359084 scopus 로고    scopus 로고
    • Function and biological roles of the Dickkopf family of Wnt modulators
    • Niehrs C. Function and biological roles of the Dickkopf family of Wnt modulators. Oncogene 2006;25: 7469-81.
    • (2006) Oncogene , vol.25 , pp. 7469-7481
    • Niehrs, C.1
  • 27
    • 0032556910 scopus 로고    scopus 로고
    • Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
    • Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 1998;391: 357-62.
    • (1998) Nature , vol.391 , pp. 357-362
    • Glinka, A.1    Wu, W.2    Delius, H.3    Monaghan, A.P.4    Blumenstock, C.5    Niehrs, C.6
  • 28
    • 2342430345 scopus 로고    scopus 로고
    • LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: Arrows point the way
    • He X, Semenov M, Tamai K, Zeng X. LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development 2004;131: 1663-77.
    • (2004) Development , vol.131 , pp. 1663-1677
    • He, X.1    Semenov, M.2    Tamai, K.3    Zeng, X.4
  • 29
    • 13244299109 scopus 로고    scopus 로고
    • FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development
    • Chamorro MN, Schwartz DR, Vonica A, Brivanlou AH, Cho KR, Varmus HE. FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development. EMBO J 2005; 24: 73-84.
    • (2005) EMBO J , vol.24 , pp. 73-84
    • Chamorro, M.N.1    Schwartz, D.R.2    Vonica, A.3    Brivanlou, A.H.4    Cho, K.R.5    Varmus, H.E.6
  • 30
    • 2442680430 scopus 로고    scopus 로고
    • Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin
    • Gonzalez-Sancho JM, Brennan KR, Castelo-Soccio LA, Brown AM. Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin. Mol Cell Biol 2004;24: 4757-68.
    • (2004) Mol Cell Biol , vol.24 , pp. 4757-4768
    • Gonzalez-Sancho, J.M.1    Brennan, K.R.2    Castelo-Soccio, L.A.3    Brown, A.M.4
  • 31
    • 9144240010 scopus 로고    scopus 로고
    • DKK1, a negative regulator of Wnt signaling, is a target of the betacatenin/TCF pathway
    • Niida A, Hiroko T, Kasai M, Furukawa Y, Nakamura Y, Suzuki Y, et al. DKK1, a negative regulator of Wnt signaling, is a target of the betacatenin/TCF pathway. Oncogene 2004;23: 8520-6.
    • (2004) Oncogene , vol.23 , pp. 8520-8526
    • Niida, A.1    Hiroko, T.2    Kasai, M.3    Furukawa, Y.4    Nakamura, Y.5    Suzuki, Y.6
  • 32
    • 0032904239 scopus 로고    scopus 로고
    • Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics
    • Carlesso N, Aster JC, Sklar J, Scadden DT. Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics. Blood 1999;93: 838-48.
    • (1999) Blood , vol.93 , pp. 838-848
    • Carlesso, N.1    Aster, J.C.2    Sklar, J.3    Scadden, D.T.4
  • 33
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    • Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997;275: 1787-90.
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3    Barker, N.4    Clevers, H.5    Vogelstein, B.6
  • 34
    • 32844454531 scopus 로고    scopus 로고
    • Wnt/Frizzled signaling in hepatocellular carcinoma
    • Lee HC, Kim M, Wands JR. Wnt/Frizzled signaling in hepatocellular carcinoma. Front Biosci 2006;11: 1901-15.
    • (2006) Front Biosci , vol.11 , pp. 1901-1915
    • Lee, H.C.1    Kim, M.2    Wands, J.R.3
  • 35
    • 0031694577 scopus 로고    scopus 로고
    • Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6JAPCMin/+ mice
    • Lefebvre AM, Chen I, Desreumaux P, Najib J, Fruchart JC, Geboes K, et al. Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6JAPCMin/+ mice. Nat Med 1998;4: 1053-7.
    • (1998) Nat Med , vol.4 , pp. 1053-1057
    • Lefebvre, A.M.1    Chen, I.2    Desreumaux, P.3    Najib, J.4    Fruchart, J.C.5    Geboes, K.6
  • 38
    • 33745765883 scopus 로고    scopus 로고
    • Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer
    • Aguilera O, Fraga MF, Ballestar E, Paz MF, Herranz M, Espada J, et al. Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer. Oncogene 2006;25: 4116-21.
    • (2006) Oncogene , vol.25 , pp. 4116-4121
    • Aguilera, O.1    Fraga, M.F.2    Ballestar, E.3    Paz, M.F.4    Herranz, M.5    Espada, J.6
  • 39
    • 0035902050 scopus 로고    scopus 로고
    • LDL-receptorrelated protein 6 is a receptor for Dickkopf proteins
    • Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, et al. LDL-receptorrelated protein 6 is a receptor for Dickkopf proteins. Nature 2001; 411: 321-5.
    • (2001) Nature , vol.411 , pp. 321-325
    • Mao, B.1    Wu, W.2    Li, Y.3    Hoppe, D.4    Stannek, P.5    Glinka, A.6
  • 40
    • 0029011129 scopus 로고
    • Induction and stabilization of i kappa B alpha by nitric oxide mediates inhibition of NF-kappa B
    • Peng HB, Libby P, Liao JK. Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B. J Biol Chem 1995;270: 14214-9.
    • (1995) J Biol Chem , vol.270 , pp. 14214-14219
    • Peng, H.B.1    Libby, P.2    Liao, J.K.3
  • 41
    • 0030658979 scopus 로고    scopus 로고
    • Nitric oxide down-regulates hepatocyte-inducible nitric oxide synthase gene expression
    • Taylor BS, Kim YM, Wang Q, Shapiro RA, Billiar TR, Geller DA. Nitric oxide down-regulates hepatocyte-inducible nitric oxide synthase gene expression. Arch Surg 1997;132: 1177-83.
    • (1997) Arch Surg , vol.132 , pp. 1177-1183
    • Taylor, B.S.1    Kim, Y.M.2    Wang, Q.3    Shapiro, R.A.4    Billiar, T.R.5    Geller, D.A.6
  • 42
    • 84867332710 scopus 로고    scopus 로고
    • Helicobacter pylori induces promoter methylation of E-cadherin via interleukin- 1beta activation of nitric oxide production in gastric cancer cells
    • Huang FY, Chan AO, Rashid A, Wong DK, Cho CH, Yuen MF. Helicobacter pylori induces promoter methylation of E-cadherin via interleukin- 1beta activation of nitric oxide production in gastric cancer cells. Cancer 2012;118: 4969-80.
    • (2012) Cancer , vol.118 , pp. 4969-4980
    • Huang, F.Y.1    Chan, A.O.2    Rashid, A.3    Wong, D.K.4    Cho, C.H.5    Yuen, M.F.6
  • 43
    • 67349139181 scopus 로고    scopus 로고
    • Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma
    • Akiri G, Cherian MM, Vijayakumar S, Liu G, Bafico A, Aaronson SA. Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma. Oncogene 2009; 28: 2163-72.
    • (2009) Oncogene , vol.28 , pp. 2163-2172
    • Akiri, G.1    Cherian, M.M.2    Vijayakumar, S.3    Liu, G.4    Bafico, A.5    Aaronson, S.A.6
  • 44
    • 7944230668 scopus 로고    scopus 로고
    • An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells
    • Bafico A, Liu G, Goldin L, Harris V, Aaronson SA. An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells. Cancer Cell 2004;6: 497-506.
    • (2004) Cancer Cell , vol.6 , pp. 497-506
    • Bafico, A.1    Liu, G.2    Goldin, L.3    Harris, V.4    Aaronson, S.A.5
  • 46
    • 0037829660 scopus 로고    scopus 로고
    • Canonical Wnt signals are essential for homeostasis of the intestinal epithelium
    • Pinto D, Gregorieff A, Begthel H, Clevers H. Canonical Wnt signals are essential for homeostasis of the intestinal epithelium. Genes Dev 2003;17: 1709-13.
    • (2003) Genes Dev , vol.17 , pp. 1709-1713
    • Pinto, D.1    Gregorieff, A.2    Begthel, H.3    Clevers, H.4
  • 48
    • 0029658030 scopus 로고    scopus 로고
    • The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression
    • Missero C, Di CF, Kiyokawa H, Koff A, Dotto GP. The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression. Genes Dev 1996;10: 3065-75.
    • (1996) Genes Dev , vol.10 , pp. 3065-3075
    • Missero, C.1    Di, C.F.2    Kiyokawa, H.3    Koff, A.4    Dotto, G.P.5
  • 49
    • 0036532056 scopus 로고    scopus 로고
    • Differential effects of p21(WAF1/CIP1) deficiency on MMTV-ras and MMTV-myc mammary tumor properties
    • Bearss DJ, Lee RJ, Troyer DA, Pestell RG, Windle JJ. Differential effects of p21(WAF1/CIP1) deficiency on MMTV-ras and MMTV-myc mammary tumor properties. Cancer Res 2002;62: 2077-84.
    • (2002) Cancer Res , vol.62 , pp. 2077-2084
    • Bearss, D.J.1    Lee, R.J.2    Troyer, D.A.3    Pestell, R.G.4    Windle, J.J.5
  • 50
    • 18644373146 scopus 로고    scopus 로고
    • The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
    • van de WM, Sancho E, Verweij C, de LW, Oving I, Hurlstone A, et al. The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 2002;111: 241-50.
    • (2002) Cell , vol.111 , pp. 241-250
    • Van De, W.M.1    Sancho, E.2    Verweij, C.3    De, L.W.4    Oving, I.5    Hurlstone, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.