Polyphenols as mitochondria-targeted anticancer drugs

Cancer Letters

Volumn 366, Issue 2, 2015, Pages 141-149

  Gorlach, Sylwia ^a   Fichna, Jakub ^a   Lewandowska, Urszula ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Cancer; Chemoprevention; Derivative; Flavonoid

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; ADENINE NUCLEOTIDE TRANSLOCASE; ANTINEOPLASTIC AGENT; BH3 PROTEIN; CATION; GOSSYPOL; HEXOKINASE; HEXOKINASE INHIBITOR; MITOCAN DERIVATIVE; MITOCHONDRIAL DNA; MITOCHONDRIOTROPIC DERIVATIVE; NAVITOCLAX; POLYPHENOL DERIVATIVE; THIOL REDOX INHIBITOR; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL; N [2 [(4 HYDROXYPHENYL)AMINO] 3 PYRIDINYL] 4 METHOXYBENZENESULFONAMIDE; POLYPHENOL; PROTEIN BCL 2; SULFONAMIDE; VDAC1 PROTEIN, HUMAN; VOLTAGE DEPENDENT ANION CHANNEL 1;

APOPTOSIS; BIOLOGICAL ACTIVITY; BREAST CARCINOMA; CANCER CELL; CELL DEATH; CITRIC ACID CYCLE; HUMAN; IN VITRO STUDY; LEUKEMIA; LIPOPHILICITY; MEMBRANE STRUCTURE; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOLECULARLY TARGETED THERAPY; NONHUMAN; OXIDATION REDUCTION REACTION; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN DOMAIN; RESPIRATORY CHAIN; SHORT SURVEY; SIGNAL TRANSDUCTION; TARGET CELL DESTRUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; METABOLISM;

ANIMALS; ANTINEOPLASTIC AGENTS; CITRIC ACID CYCLE; DNA, MITOCHONDRIAL; GOSSYPOL; HEXOKINASE; HUMANS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; OXIDATION-REDUCTION; POLYPHENOLS; PROTO-ONCOGENE PROTEINS C-BCL-2; SULFONAMIDES; VOLTAGE-DEPENDENT ANION CHANNEL 1;

EID: 84937913443     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2015.07.004     Document Type: Review

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