메뉴 건너뛰기




Volumn 583, Issue 4, 2009, Pages 643-647

Kaempferol is an estrogen-related receptor α and γ inverse agonist

Author keywords

Estrogen receptor; Estrogen related receptor; Kaempferol

Indexed keywords

ESTROGEN RECEPTOR; ESTROGEN RELATED RECEPTOR ALPHA; ESTROGEN RELATED RECEPTOR GAMMA; KAEMPFEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PYRUVATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE KINASE 2; PYRUVATE DEHYDROGENASE KINASE 4; UNCLASSIFIED DRUG;

EID: 59849083230     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.01.030     Document Type: Article
Times cited : (73)

References (22)
  • 2
    • 0034466972 scopus 로고    scopus 로고
    • Estrogen receptor transcription and transactivation: estrogen receptor-alpha and estrogen receptor beta - regulation by selective estrogen receptor modulators and importance in breast cancer
    • Katzenellenbogen S.B., and Katzenellenbogen J.A. Estrogen receptor transcription and transactivation: estrogen receptor-alpha and estrogen receptor beta - regulation by selective estrogen receptor modulators and importance in breast cancer. Breast Cancer Res. 2 (2000) 335-344
    • (2000) Breast Cancer Res. , vol.2 , pp. 335-344
    • Katzenellenbogen, S.B.1    Katzenellenbogen, J.A.2
  • 3
    • 53049102012 scopus 로고    scopus 로고
    • Separation of quercetin, sexangularetin, kaempferol and isorhamnetin for simultaneous HPLC determination of flavonoid aglycones in inflorescences, leaves and fruits of three Sorbus species
    • Olszewska M. Separation of quercetin, sexangularetin, kaempferol and isorhamnetin for simultaneous HPLC determination of flavonoid aglycones in inflorescences, leaves and fruits of three Sorbus species. J. Pharm. Biomed. Anal. 48 (2008) 629-635
    • (2008) J. Pharm. Biomed. Anal. , vol.48 , pp. 629-635
    • Olszewska, M.1
  • 5
    • 0028068478 scopus 로고
    • Kaempferol-induced nuclear DNA damage and lipid peroxidation
    • Sahu S.C., and Gray G.C. Kaempferol-induced nuclear DNA damage and lipid peroxidation. Cancer Lett. 85 (1994) 159-164
    • (1994) Cancer Lett. , vol.85 , pp. 159-164
    • Sahu, S.C.1    Gray, G.C.2
  • 6
    • 45049088538 scopus 로고    scopus 로고
    • Ginkgo biloba extract kaempferol inhibits cell proliferation and induces apoptosis in pancreatic cancer cells
    • Zhang Y., Chen A.Y., Li M., Chen C., and Yao Q. Ginkgo biloba extract kaempferol inhibits cell proliferation and induces apoptosis in pancreatic cancer cells. J. Surg. Res. 148 (2008) 17-23
    • (2008) J. Surg. Res. , vol.148 , pp. 17-23
    • Zhang, Y.1    Chen, A.Y.2    Li, M.3    Chen, C.4    Yao, Q.5
  • 7
    • 0036400016 scopus 로고    scopus 로고
    • Dietary flavonoids: bioavailability, metabolic effects, and safety
    • Ross J.A., and Kasum C.M. Dietary flavonoids: bioavailability, metabolic effects, and safety. Annu. Rev. Nutr. 22 (2002) 19-34
    • (2002) Annu. Rev. Nutr. , vol.22 , pp. 19-34
    • Ross, J.A.1    Kasum, C.M.2
  • 8
    • 0033305499 scopus 로고    scopus 로고
    • Orphan nuclear receptors: from gene to function
    • 10.1210/er.20.5.689
    • Giguere V. Orphan nuclear receptors: from gene to function. Endocr. Rev. 20 (1999) 689-725 10.1210/er.20.5.689
    • (1999) Endocr. Rev. , vol.20 , pp. 689-725
    • Giguere, V.1
  • 9
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • Mangelsdorf D.J., and Evans R.M. The RXR heterodimers and orphan receptors. Cell 83 (1995) 841-850
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 10
    • 0035902557 scopus 로고    scopus 로고
    • 4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor gamma
    • 10.1073/pnas.151244398
    • Coward P., Lee D., Hull M.V., and Lehmann J.M. 4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor gamma. PNAS 98 (2001) 8880-8884 10.1073/pnas.151244398
    • (2001) PNAS , vol.98 , pp. 8880-8884
    • Coward, P.1    Lee, D.2    Hull, M.V.3    Lehmann, J.M.4
  • 11
    • 0034812571 scopus 로고    scopus 로고
    • 4-Hydroxytamoxifen is an isoform-specific inhibitor of orphan estrogen-receptor-related (ERR) nuclear receptors beta and gamma
    • 10.1210/en.142.10.4572
    • Tremblay G.B., Bergeron D., and Giguere V. 4-Hydroxytamoxifen is an isoform-specific inhibitor of orphan estrogen-receptor-related (ERR) nuclear receptors beta and gamma. Endocrinology 142 (2001) 4572-4575 10.1210/en.142.10.4572
    • (2001) Endocrinology , vol.142 , pp. 4572-4575
    • Tremblay, G.B.1    Bergeron, D.2    Giguere, V.3
  • 12
    • 13944270955 scopus 로고    scopus 로고
    • Identification of an agonist ligand for estrogen-related receptors ERR[beta]/[gamma]
    • Yu D.D., and Forman B.M. Identification of an agonist ligand for estrogen-related receptors ERR[beta]/[gamma]. Bioorg. Med. Chem. Lett. 15 (2005) 1311-1313
    • (2005) Bioorg. Med. Chem. Lett. , vol.15 , pp. 1311-1313
    • Yu, D.D.1    Forman, B.M.2
  • 13
    • 0035312745 scopus 로고    scopus 로고
    • Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERR{beta}
    • 10.1101/gad.873401
    • Tremblay G.B., Kunath T., Bergeron D., Lapointe L., Champigny C., Bader J.-A., Rossant J., and Giguere V. Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERR{beta}. Genes Dev. 15 (2001) 833-838 10.1101/gad.873401
    • (2001) Genes Dev. , vol.15 , pp. 833-838
    • Tremblay, G.B.1    Kunath, T.2    Bergeron, D.3    Lapointe, L.4    Champigny, C.5    Bader, J.-A.6    Rossant, J.7    Giguere, V.8
  • 14
    • 28544438180 scopus 로고    scopus 로고
    • PGC-1{alpha} coactivates PDK4 gene expression via the orphan nuclear receptor ERR{alpha}: a mechanism for transcriptional control of muscle glucose metabolism
    • Wende A.R., Huss J.M., Schaeffer P.J., Giguere V., and Kelly D.P. PGC-1{alpha} coactivates PDK4 gene expression via the orphan nuclear receptor ERR{alpha}: a mechanism for transcriptional control of muscle glucose metabolism. Mol. Cell. Biol. 25 (2005) 10684-10694
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 10684-10694
    • Wende, A.R.1    Huss, J.M.2    Schaeffer, P.J.3    Giguere, V.4    Kelly, D.P.5
  • 15
    • 0038660688 scopus 로고    scopus 로고
    • The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor-alpha (ERRalpha)
    • Schreiber S.N., Knutti D., Brogli K., Uhlmann T., and Kralli A. The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor-alpha (ERRalpha). J. Biol. Chem. 278 (2003) 9013-9018
    • (2003) J. Biol. Chem. , vol.278 , pp. 9013-9018
    • Schreiber, S.N.1    Knutti, D.2    Brogli, K.3    Uhlmann, T.4    Kralli, A.5
  • 17
    • 0037174798 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha
    • 10.1074/jbc.M206324200
    • Huss J.M., Kopp R.P., and Kelly D.P. Peroxisome proliferator-activated receptor-coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha. J. Biol. Chem 277 (2002) 40265-40274 10.1074/jbc.M206324200
    • (2002) J. Biol. Chem , vol.277 , pp. 40265-40274
    • Huss, J.M.1    Kopp, R.P.2    Kelly, D.P.3
  • 18
    • 33845973409 scopus 로고    scopus 로고
    • Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 (PDK4) gene expressions
    • 10.1074/jbc.M608657200
    • Zhang Y., et al. Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 (PDK4) gene expressions. J. Biol. Chem. 2 (2006) M608657200 10.1074/jbc.M608657200
    • (2006) J. Biol. Chem. , vol.2
    • Zhang, Y.1
  • 19
    • 0033564553 scopus 로고    scopus 로고
    • Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially
    • Ciolino H.P., Daschner P.J., and Yeh G.C. Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially. Biochem. J. 340 (1999) 715-722
    • (1999) Biochem. J. , vol.340 , pp. 715-722
    • Ciolino, H.P.1    Daschner, P.J.2    Yeh, G.C.3
  • 20
  • 21
    • 53849088227 scopus 로고    scopus 로고
    • Transcriptional control of energy homeostasis by the estrogen-related receptors
    • Giguere V. Transcriptional control of energy homeostasis by the estrogen-related receptors. Endocr. Rev. 29 (2008) 677-696
    • (2008) Endocr. Rev. , vol.29 , pp. 677-696
    • Giguere, V.1
  • 22
    • 33846876099 scopus 로고    scopus 로고
    • Estrogen-related receptor as a therapeutic target in cancer
    • Stein R.A., and McDonnell D.P. Estrogen-related receptor as a therapeutic target in cancer. Endocr. Rel. Cancer 13 (2006) S25-S32
    • (2006) Endocr. Rel. Cancer , vol.13
    • Stein, R.A.1    McDonnell, D.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.