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Volumn 28, Issue 7, 2007, Pages 1446-1454

The suppression of aberrant crypt multiplicity in colonic tissue of 1,2-dimethylhydrazine-treated C57BL/6J mice by dietary flavone is associated with an increased expression of Krebs cycle enzymes

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIMETHYLHYDRAZINE; CARCINOGEN; CELL ENZYME; FLAVONE; FLAVONOID; PROTEOME;

EID: 34547771684     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgm040     Document Type: Article
Times cited : (14)

References (42)
  • 2
    • 0034118071 scopus 로고    scopus 로고
    • Colon heat and colon cancer
    • Holmqvist,O.H. (2000) Colon heat and colon cancer. Med. Hypotheses 54, 469-471.
    • (2000) Med. Hypotheses , vol.54 , pp. 469-471
    • Holmqvist, O.H.1
  • 3
    • 0036656220 scopus 로고    scopus 로고
    • Nutritional chemoprevention of colon cancer
    • Mason,J.B. (2002) Nutritional chemoprevention of colon cancer. Semin. Gastrointest. Dis, 13, 143-153.
    • (2002) Semin. Gastrointest. Dis , vol.13 , pp. 143-153
    • Mason, J.B.1
  • 4
    • 0026761445 scopus 로고
    • Intake of vegetables, fruits, beta-carotene, vitamin C and vitamin supplements and cancer incidence among the elderly: A prospective study
    • Shibata,A. et al. (1992) Intake of vegetables, fruits, beta-carotene, vitamin C and vitamin supplements and cancer incidence among the elderly: A prospective study. Br. J. Cancer, 66, 673-679.
    • (1992) Br. J. Cancer , vol.66 , pp. 673-679
    • Shibata, A.1
  • 5
    • 0029912852 scopus 로고    scopus 로고
    • Flavonoids activate wild-type p53
    • Plaumann,B. et al. (1996) Flavonoids activate wild-type p53. Oncogene, 13, 1605-1614.
    • (1996) Oncogene , vol.13 , pp. 1605-1614
    • Plaumann, B.1
  • 6
    • 0031656217 scopus 로고    scopus 로고
    • Flavonoids: Inhibitors of cytokine induced gene expression
    • Gerritsen,M.E. (1998) Flavonoids: Inhibitors of cytokine induced gene expression. Adv. Exp. Med. Biol, 439, 183-190.
    • (1998) Adv. Exp. Med. Biol , vol.439 , pp. 183-190
    • Gerritsen, M.E.1
  • 7
    • 22844436771 scopus 로고    scopus 로고
    • Chemopreventive properties of apple procyanidins on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis
    • Gosse,F. et al. (2005) Chemopreventive properties of apple procyanidins on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis. Carcinogenesis, 26, 1291-1295.
    • (2005) Carcinogenesis , vol.26 , pp. 1291-1295
    • Gosse, F.1
  • 8
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan,D. et al. (2000) The hallmarks of cancer. Cell, 100, 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1
  • 9
    • 0034899450 scopus 로고    scopus 로고
    • Suppression of apoptosis: Role in cell growth and neoplasia
    • White,M.K. et al. (2001) Suppression of apoptosis: Role in cell growth and neoplasia. Leukemia, 15, 1011-1021.
    • (2001) Leukemia , vol.15 , pp. 1011-1021
    • White, M.K.1
  • 10
    • 33644931093 scopus 로고    scopus 로고
    • Colon cancer and apoptosis
    • Huerta,S. et al. (2006) Colon cancer and apoptosis. Am. J. Surg 191, 517-526.
    • (2006) Am. J. Surg , vol.191 , pp. 517-526
    • Huerta, S.1
  • 11
    • 0032815147 scopus 로고    scopus 로고
    • Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines
    • Kuntz,S. et al. (1999) Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines. Eur. J. Nutr, 38, 133-142.
    • (1999) Eur. J. Nutr , vol.38 , pp. 133-142
    • Kuntz, S.1
  • 12
    • 0034660863 scopus 로고    scopus 로고
    • Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells
    • Wenzel,U. et al. (2000) Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells. Cancer Res, 60, 3823-3831.
    • (2000) Cancer Res , vol.60 , pp. 3823-3831
    • Wenzel, U.1
  • 13
    • 0345735765 scopus 로고    scopus 로고
    • NO-levels in human preneoplastic colonocytes determine their susceptibility towards anti-neoplastic agents
    • Wenzel,U. et al. (2003) NO-levels in human preneoplastic colonocytes determine their susceptibility towards anti-neoplastic agents. Mol. Pharmacol, 64, 1494-1502.
    • (2003) Mol. Pharmacol , vol.64 , pp. 1494-1502
    • Wenzel, U.1
  • 14
    • 0042524358 scopus 로고    scopus 로고
    • Nitric oxide suppresses apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions
    • Wenzel,U. et al. (2003) Nitric oxide suppresses apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions. Int. J. Cancer, 106, 666-675.
    • (2003) Int. J. Cancer , vol.106 , pp. 666-675
    • Wenzel, U.1
  • 15
    • 2442501565 scopus 로고    scopus 로고
    • Ascorbic acid suppresses drug-induced apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions
    • Wenzel,U. et al. (2004) Ascorbic acid suppresses drug-induced apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions. Carcinogenesis, 25, 703-712.
    • (2004) Carcinogenesis , vol.25 , pp. 703-712
    • Wenzel, U.1
  • 16
    • 11144258924 scopus 로고    scopus 로고
    • Activation of mitochondrial lactate uptake by flavone induces apoptosis in human colon cancer cells
    • Wenzel,U. et al. (2005) Activation of mitochondrial lactate uptake by flavone induces apoptosis in human colon cancer cells. J. Cell. Physiol, 202, 379-390.
    • (2005) J. Cell. Physiol , vol.202 , pp. 379-390
    • Wenzel, U.1
  • 17
    • 22044458158 scopus 로고    scopus 로고
    • Melatonin potentiates flavone-induced apoptosis in human colon cancer cells by increasing the level of glycolytic end products
    • Wenzel,U. et al. (2005) Melatonin potentiates flavone-induced apoptosis in human colon cancer cells by increasing the level of glycolytic end products. Int. J. Cancer, 116, 236-242.
    • (2005) Int. J. Cancer , vol.116 , pp. 236-242
    • Wenzel, U.1
  • 18
    • 0346337126 scopus 로고    scopus 로고
    • Aberrant crypt foci as microscopic precursors of colorectal cancer
    • Cheng,L et al. (2003) Aberrant crypt foci as microscopic precursors of colorectal cancer. World J. Gastroenterol, 9, 2642-2649.
    • (2003) World J. Gastroenterol , vol.9 , pp. 2642-2649
    • Cheng, L.1
  • 19
    • 5144232016 scopus 로고    scopus 로고
    • The potent colon carcinogen, 1,2-dimethylhydrazine induces mutations primarily in the colon
    • Newell,E. et al. (2004) The potent colon carcinogen, 1,2-dimethylhydrazine induces mutations primarily in the colon. Mutat. Res, 564, 1-7.
    • (2004) Mutat. Res , vol.564 , pp. 1-7
    • Newell, E.1
  • 20
    • 0033862118 scopus 로고    scopus 로고
    • Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon
    • Yang,K. et al. (2000) Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon. Carcinogenesis, 21, 1655-1660.
    • (2000) Carcinogenesis , vol.21 , pp. 1655-1660
    • Yang, K.1
  • 21
    • 0034019660 scopus 로고    scopus 로고
    • Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis
    • Mahmoud,N.N. et al. (2000) Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis. Carcinogenesis, 21, 921-927.
    • (2000) Carcinogenesis , vol.21 , pp. 921-927
    • Mahmoud, N.N.1
  • 22
    • 0033863355 scopus 로고    scopus 로고
    • Dietary intake and bioavailability of polyphenols
    • Scalbert,A. et al. (2000) Dietary intake and bioavailability of polyphenols. J. Nutr, 130, 2073S-2085S.
    • (2000) J. Nutr , vol.130
    • Scalbert, A.1
  • 23
    • 0034095972 scopus 로고    scopus 로고
    • The current state of two-dimensional electrophoresis with immobilized pH gradients
    • Görg,A. et al. (2000) The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis, 21, 1037-1053.
    • (2000) Electrophoresis , vol.21 , pp. 1037-1053
    • Görg, A.1
  • 24
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli,U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 25
    • 0028904619 scopus 로고
    • Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon
    • Zaidi,N.H. et al. (1995) Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon. Carcinogenesis, 16, 451-456.
    • (1995) Carcinogenesis , vol.16 , pp. 451-456
    • Zaidi, N.H.1
  • 26
    • 0025999838 scopus 로고
    • Sequential analyses of the growth and morphological characteristics of aberrant crypt foci: Putative preneoplastic lesions
    • McLellan,E.A. et al. (1991) Sequential analyses of the growth and morphological characteristics of aberrant crypt foci: Putative preneoplastic lesions. Cancer Res, 51, 5270-5274.
    • (1991) Cancer Res , vol.51 , pp. 5270-5274
    • McLellan, E.A.1
  • 27
    • 0027023015 scopus 로고
    • Aberrant crypts in human colonic mucosa: Putative preneoplastic lesions
    • Pretlow,T.P. et al. (1992) Aberrant crypts in human colonic mucosa: Putative preneoplastic lesions. J. Cell. Biochem, 16G 55-62.
    • (1992) J. Cell. Biochem , vol.16 G , pp. 55-62
    • Pretlow, T.P.1
  • 28
    • 4344577385 scopus 로고    scopus 로고
    • Clinical management of hereditary colorectal cancer syndromes
    • Half,E.E. et al. (2004) Clinical management of hereditary colorectal cancer syndromes. Curr. Opin. Gastroenterol, 20, 32-42.
    • (2004) Curr. Opin. Gastroenterol , vol.20 , pp. 32-42
    • Half, E.E.1
  • 29
    • 0028576901 scopus 로고
    • Dietary factors and risk of colon cancer
    • Giovannucci,E. et al. (1994) Dietary factors and risk of colon cancer. Ann. Med., 26, 443-452.
    • (1994) Ann. Med , vol.26 , pp. 443-452
    • Giovannucci, E.1
  • 30
    • 0027485394 scopus 로고
    • The effect of dietary quercetin and rutin on AOM-induced acute colonic epithelial abnormalities in mice fed a high-fat diet
    • Deschner,E.E. et al. (1993) The effect of dietary quercetin and rutin on AOM-induced acute colonic epithelial abnormalities in mice fed a high-fat diet. Nutr. Cancer, 20, 199-204.
    • (1993) Nutr. Cancer , vol.20 , pp. 199-204
    • Deschner, E.E.1
  • 31
    • 0027361049 scopus 로고
    • Ability of aberrant crypt foci characteristics to predict colonic tumor incidence in rats fed cholic acid
    • Magnuson,B.A. et al. (1993) Ability of aberrant crypt foci characteristics to predict colonic tumor incidence in rats fed cholic acid. Cancer Res, 53, 4499-4504.
    • (1993) Cancer Res , vol.53 , pp. 4499-4504
    • Magnuson, B.A.1
  • 32
    • 33751116839 scopus 로고    scopus 로고
    • Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats
    • Dihal,A.A. et al. (2006) Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats. J. Nutr, 136, 2862-2867.
    • (2006) J. Nutr , vol.136 , pp. 2862-2867
    • Dihal, A.A.1
  • 33
    • 33646240050 scopus 로고    scopus 로고
    • Functional proteomics of resveratrol-induced colon cancer cell apoptosis: Caspase-6-mediated cleavage of lamin A is a major signaling loop
    • Lee,S.C. et al. (2006) Functional proteomics of resveratrol-induced colon cancer cell apoptosis: Caspase-6-mediated cleavage of lamin A is a major signaling loop. Proteomics, 6 2386-2394.
    • (2006) Proteomics , vol.6 , pp. 2386-2394
    • Lee, S.C.1
  • 34
    • 13244249555 scopus 로고    scopus 로고
    • Assessment of apoptosis by immunohistochemical markers compared to cellular morphology in ex vivo-stressed colonic mucosa
    • Holubec,H. et al. (2005) Assessment of apoptosis by immunohistochemical markers compared to cellular morphology in ex vivo-stressed colonic mucosa. J. Histochem. Cytochem, 53, 229-235.
    • (2005) J. Histochem. Cytochem , vol.53 , pp. 229-235
    • Holubec, H.1
  • 35
    • 0036545332 scopus 로고    scopus 로고
    • Lactate shuttles in nature
    • Brooks,G.A. (2002) Lactate shuttles in nature. Biochem. Soc. Trans 30, 258-264.
    • (2002) Biochem. Soc. Trans , vol.30 , pp. 258-264
    • Brooks, G.A.1
  • 36
    • 0029081536 scopus 로고
    • The potential role of transformation-induced metabolic changes in tumor-host interaction
    • Gatenby,R.A. (1995) The potential role of transformation-induced metabolic changes in tumor-host interaction. Cancer Res, 55, 4151-4156.
    • (1995) Cancer Res , vol.55 , pp. 4151-4156
    • Gatenby, R.A.1
  • 37
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • Gatenby,R.A. et al. (2004) Why do cancers have high aerobic glycolysis? Nat. Rev. Cancer, 4, 891-899.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 891-899
    • Gatenby, R.A.1
  • 38
    • 3543058843 scopus 로고    scopus 로고
    • Pleiotropic molecular effects of the pro-apoptotic dietary constituent flavone in human colon cancer cells identified by protein and mRNA expression profiling
    • Herzog,A. et al. (2004) Pleiotropic molecular effects of the pro-apoptotic dietary constituent flavone in human colon cancer cells identified by protein and mRNA expression profiling. Proteomics, 4, 2455-2464.
    • (2004) Proteomics , vol.4 , pp. 2455-2464
    • Herzog, A.1
  • 39
    • 20444408453 scopus 로고    scopus 로고
    • Increased carnitine-dependent fatty acid uptake into mitochondria of human colon cancer cells induces apoptosis
    • Wenzel,U. et al. (2005) Increased carnitine-dependent fatty acid uptake into mitochondria of human colon cancer cells induces apoptosis. J. Nutr, 135, 1510-1514.
    • (2005) J. Nutr , vol.135 , pp. 1510-1514
    • Wenzel, U.1
  • 40
    • 0025004005 scopus 로고
    • Subunit location and sequences of the cysteinyl peptides of pig heart NAD-dependent isocitrate dehydrogenase
    • Huang,Y.C. et al. (1990) Subunit location and sequences of the cysteinyl peptides of pig heart NAD-dependent isocitrate dehydrogenase. Biochemistry, 29, 8266-8273.
    • (1990) Biochemistry , vol.29 , pp. 8266-8273
    • Huang, Y.C.1
  • 41
    • 0018972968 scopus 로고
    • Enzyme activities in human fetal and neoplastic tissues
    • Herzfeld,A. et al. (1980) Enzyme activities in human fetal and neoplastic tissues. Cancer, 46, 2047-2054.
    • (1980) Cancer , vol.46 , pp. 2047-2054
    • Herzfeld, A.1
  • 42
    • 33845273100 scopus 로고    scopus 로고
    • Pro-oxidant activity of flavonoids induces EpRE-mediated gene expression
    • Lee-Hilz,Y.Y. et al. (2006) Pro-oxidant activity of flavonoids induces EpRE-mediated gene expression. Chem. Res. Toxicol, 19 1499-1505.
    • (2006) Chem. Res. Toxicol , vol.19 , pp. 1499-1505
    • Lee-Hilz, Y.Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.